Strain: SD-Cntnap2em1Sage

Symbol: SD-Cntnap2em1Sage
Strain: SD-Cntnap2em1
Substrain: Sage
Ontology ID: RS:0004310
Alleles: Cntnap2em1Sage
Also known as: SD-Cntnap2tm1Sage; TGRS8820; SD-Cntnap2em1Sage
Type: mutant
Source: Horizon Discovery
Origin: The ZFN mutant rat strain was produced by injecting zinc finger nuclease targeting rat Met into Sprague Dawley embryos. The resulting mutation was a 5-bp deletion in exon 6 of Cntnap2. Homozygous knockout rats exhibit complete loss of target protein as demonstrated by Western blot.
Genetic Status: Heterozygous
Last Known Status: Live Animals (as of 2017-05-05)
Research Usage Autism Spectrum Disorders, Synaptic Plasticity, Language disorders
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0474,700,539 - 77,025,463RGD_MAPPER_PIPELINERnor6.0
Rnor_5.04140,006,078 - 141,697,964RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4474,277,978 - 75,440,178RGD_MAPPER_PIPELINERGSC3.4

Disease Annotations
Phenotype Annotations
Experimental Data Annotations
References - curated
RGD Disease Portals


Additional Information

More on this Strain
Strain Nomenclature
Strain Registration

RGD Object Information
RGD ID: 11568646
Created: 2016-12-08
Species: Rattus norvegicus
Last Modified: 2016-12-08
Status: ACTIVE