Add3 (adducin 3) - Rat Genome Database
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Gene: Add3 (adducin 3) Rattus norvegicus
Analyze
Symbol: Add3
Name: adducin 3
RGD ID: 2043
Description: Exhibits protein kinase C binding activity. Involved in positive regulation of vasoconstriction and response to drug. Localizes to cytoskeleton. Used to study hypertension. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 50. Orthologous to human ADD3 (adducin 3); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: adducin 3 (gamma); adducin 3, gamma; adducin-like protein 70; gamma-adducin; potein kinase C binding protein 35H; protein kinase C-binding protein 35H
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21252,147,341 - 252,255,126 (+)NCBI
Rnor_6.0 Ensembl1273,854,248 - 273,961,982 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01273,854,195 - 273,961,982 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01281,267,424 - 281,375,203 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41259,347,673 - 259,455,407 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11259,560,471 - 259,923,891 (-)NCBI
Celera1247,872,140 - 247,979,623 (+)NCBICelera
Cytogenetic Map1q55NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrotoluene  (EXP)
2-methylcholine  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
bexarotene  (ISO)
bisphenol A  (EXP,ISO)
carbon nanotube  (ISO)
chloroprene  (EXP)
choline  (ISO)
chrysene  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
dibutyl phthalate  (EXP)
diuron  (EXP)
doxorubicin  (ISO)
elemental selenium  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
ethanol  (ISO)
flavonoids  (EXP)
flusilazole  (EXP)
folic acid  (ISO)
furan  (EXP)
gamma-hexachlorocyclohexane  (EXP)
gentamycin  (EXP)
glyphosate  (EXP)
hydrogen peroxide  (ISO)
indometacin  (ISO)
irinotecan  (ISO)
isoprenaline  (ISO)
L-methionine  (ISO)
malathion  (EXP)
menadione  (ISO)
methylseleninic acid  (ISO)
N-nitrosodimethylamine  (EXP)
nickel sulfate  (ISO)
paclitaxel  (ISO)
paracetamol  (ISO)
parathion  (EXP)
parathion-methyl  (EXP)
phenobarbital  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
succimer  (ISO)
sunitinib  (ISO)
tamoxifen  (EXP)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (ISO)
tetraphene  (ISO)
topotecan  (ISO)
trichostatin A  (EXP)
valproic acid  (ISO)
vincaleukoblastine  (ISO)
vinclozolin  (EXP)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
brush border  (IEA,ISO)
cell cortex  (IEA,ISO)
cell-cell junction  (IEA,ISO)
condensed nuclear chromosome  (IEA,ISO)
cytoplasm  (ISO)
cytoskeleton  (IBA,IDA,IEA,ISO)
membrane  (ISO)
plasma membrane  (IBA,IEA)
plasma membrane raft  (IBA)
postsynaptic density  (IBA,IEA,ISO)

Molecular Function

References

Additional References at PubMed
PMID:1864459   PMID:8889548   PMID:9299427   PMID:12947022   PMID:17114649   PMID:22114352   PMID:31505169   PMID:32029431   PMID:33308016  


Genomics

Comparative Map Data
Add3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21252,147,341 - 252,255,126 (+)NCBI
Rnor_6.0 Ensembl1273,854,248 - 273,961,982 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01273,854,195 - 273,961,982 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01281,267,424 - 281,375,203 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41259,347,673 - 259,455,407 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11259,560,471 - 259,923,891 (-)NCBI
Celera1247,872,140 - 247,979,623 (+)NCBICelera
Cytogenetic Map1q55NCBI
ADD3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl10109,996,368 - 110,135,565 (+)EnsemblGRCh38hg38GRCh38
GRCh3810109,996,365 - 110,135,565 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3710111,756,131 - 111,895,323 (+)NCBIGRCh37GRCh37hg19GRCh37
GRCh3710111,765,627 - 111,895,323 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610111,755,716 - 111,885,313 (+)NCBINCBI36hg18NCBI36
Build 3410111,755,793 - 111,885,313NCBI
Celera10105,497,404 - 105,626,995 (+)NCBI
Cytogenetic Map10q25.1-q25.2NCBI
HuRef10105,396,619 - 105,526,176 (+)NCBIHuRef
CHM1_110112,037,774 - 112,177,067 (+)NCBICHM1_1
Add3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391953,128,874 - 53,235,757 (+)NCBIGRCm39mm39
GRCm381953,140,443 - 53,247,326 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1953,140,443 - 53,247,399 (+)EnsemblGRCm38mm10GRCm38
MGSCv371953,214,935 - 53,321,889 (+)NCBIGRCm37mm9NCBIm37
MGSCv361953,256,726 - 53,300,399 (+)NCBImm8
Celera1955,321,358 - 55,428,774 (+)NCBICelera
Cytogenetic Map19D2NCBI
cM Map1947.18NCBI
Add3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554851,216,435 - 1,353,953 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554851,216,435 - 1,273,275 (-)NCBIChiLan1.0ChiLan1.0
ADD3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.110110,048,680 - 110,178,671 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10110,123,270 - 110,178,671 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v010106,597,693 - 106,727,494 (+)NCBIMhudiblu_PPA_v0panPan3
ADD3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2821,403,680 - 21,525,063 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12821,402,068 - 21,527,006 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Add3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936486928,956 - 1,042,168 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADD3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14120,451,573 - 120,583,723 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114120,451,421 - 120,583,725 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214131,288,509 - 131,420,807 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ADD3
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19102,930,270 - 103,056,558 (+)NCBI
ChlSab1.1 Ensembl9103,010,713 - 103,057,101 (+)Ensembl
Add3
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473736,091,671 - 36,256,398 (-)NCBI

Position Markers
D1Got253  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01273,930,544 - 273,930,686NCBIRnor6.0
Rnor_5.01281,343,765 - 281,343,907UniSTSRnor5.0
RGSC_v3.41259,378,968 - 259,379,111RGDRGSC3.4
RGSC_v3.41259,378,969 - 259,379,111UniSTSRGSC3.4
RGSC_v3.11259,590,014 - 259,590,156RGD
Celera1247,948,325 - 247,948,467UniSTS
RH 3.4 Map11665.0RGD
RH 3.4 Map11665.0UniSTS
RH 2.0 Map11286.0999RGD
Cytogenetic Map1q55UniSTS
RH127841  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01273,961,661 - 273,961,879NCBIRnor6.0
Rnor_5.01281,374,882 - 281,375,100UniSTSRnor5.0
RGSC_v3.41259,347,776 - 259,347,994UniSTSRGSC3.4
Celera1247,979,302 - 247,979,520UniSTS
RH 3.4 Map11664.5UniSTS
Cytogenetic Map1q55UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70211Niddm24Non-insulin dependent diabetes mellitus QTL 243.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1236795785281795785Rat
631215Stl8Serum triglyceride level QTL 89.270.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1245529606282763074Rat
2302040Pia35Pristane induced arthritis QTL 353.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)1236265430281265430Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1156446196274977688Rat
724533Rf51Renal function QTL 515.30.0002kidney plasma flow trait (VT:0005524)renal plasma flow (CMO:0001914)1238830534278228767Rat
724552Glom2Glomerulus QTL 23.30.0001kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)1243272341282763074Rat
734767Niddm57Non-insulin dependent diabetes mellitus QTL 57body mass (VT:0001259)body weight (CMO:0000012)1244401175282365384Rat
734768Niddm59Non-insulin dependent diabetes mellitus QTL 59body mass (VT:0001259)body weight (CMO:0000012)1235850810280850810Rat
734769Niddm58Non-insulin dependent diabetes mellitus QTL 58body mass (VT:0001259)body weight (CMO:0000012)1244992467282365384Rat
631669Iddm9Insulin dependent diabetes mellitus QTL 92.80.039blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1252955158280632620Rat
631690Scl5Serum cholesterol level QTL 52.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1258132568282763074Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1167394665278228889Rat
1581544Rf52Renal function QTL 520.05total urine protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)1252948438281795785Rat
731175Uae20Urinary albumin excretion QTL 203.50.0018urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1241482188281795785Rat
738032Hcas5Hepatocarcinoma susceptibility QTL 53.12liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1191825895279986079Rat
631536Lnnr2Liver neoplastic nodule remodeling QTL 22.90.0005liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)1255728828282763074Rat
1598821Rf55Renal function QTL 556.3renal blood flow trait (VT:2000006)ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)1238824734279986079Rat
1598839Rf56Renal function QTL 56renal blood flow trait (VT:2000006)ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)1266793821279986079Rat
631836Stl31Serum triglyceride level QTL 314.640.00000487blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)1259295704282763074Rat
631837Niddm35Non-insulin dependent diabetes mellitus QTL 350.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1258709726281795785Rat
631843Bw116Body weight QTL 1164.10.016abdominal adipose amount (VT:1000220)abdominal fat pad weight (CMO:0000088)1244401175282365384Rat
634313Niddm43Non-insulin dependent diabetes mellitus QTL 43blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1217054291281795785Rat
1600388Niddm67Non-insulin dependent diabetes mellitus QTL 675.840.000004blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1213476630278978026Rat
1600392Bw123Body weight QTL 1230.001body mass (VT:0001259)body weight (CMO:0000012)1244087148282763074Rat
1600395Niddm69Non-insulin dependent diabetes mellitus QTL 694.140.0002blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1213476630278978026Rat
1600396Niddm68Non-insulin dependent diabetes mellitus QTL 684.970.0003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1213476630278978026Rat
1578763Kidm29Kidney mass QTL 293.30.0001kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1196395041282763074Rat
1300108Rf8Renal function QTL 83.75renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)1249206242281795785Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1161784169278228889Rat
1354624Cm35Cardiac mass QTL355.7heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1192639698278228889Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1161784169278228889Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1192639698278228889Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1161784169278228889Rat
1549910Bw54Body weight QTL 540.05body mass (VT:0001259)body weight (CMO:0000012)1236795785281795785Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1163796316282763074Rat
1358890Bp259Blood pressure QTL 2593.06arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1230420627282645769Rat
61327Eae7Experimental allergic encephalomyelitis QTL 75.6body mass (VT:0001259)change in body weight (CMO:0002045)1236265430281265430Rat
7387289Uae45Urinary albumin excretion QTL 452.860.0021urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1244148899282763074Rat
10053715Scort24Serum corticosterone level QTL 242.130.0088blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1242302911282763074Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:964
Count of miRNA genes:301
Interacting mature miRNAs:394
Transcripts:ENSRNOT00000017600, ENSRNOT00000044827
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 46 30 19 30 6 7 74 35 41 11 6
Low 11 11 11 2 4 2
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001164103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_031552 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006231599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006231600 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006231601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008760510 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039101448 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA899625 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC106606 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC119371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW141606 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB725075 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB757924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF111029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK596161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO402732 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM038946 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM059497 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM072500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234561 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U35775 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000017600   ⟹   ENSRNOP00000017600
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1273,854,248 - 273,961,982 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000044827   ⟹   ENSRNOP00000043399
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1273,854,248 - 273,961,982 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000086496   ⟹   ENSRNOP00000069717
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1273,854,342 - 273,960,228 (+)Ensembl
RefSeq Acc Id: NM_001164103   ⟹   NP_001157575
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21252,147,386 - 252,255,126 (+)NCBI
Rnor_6.01273,854,248 - 273,961,982 (+)NCBI
Rnor_5.01281,267,424 - 281,375,203 (+)NCBI
RGSC_v3.41259,347,673 - 259,455,407 (-)RGD
Celera1247,872,140 - 247,979,623 (+)RGD
Sequence:
RefSeq Acc Id: NM_031552   ⟹   NP_113740
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21252,147,386 - 252,255,126 (+)NCBI
Rnor_6.01273,854,248 - 273,961,982 (+)NCBI
Rnor_5.01281,267,424 - 281,375,203 (+)NCBI
RGSC_v3.41259,347,673 - 259,455,407 (-)RGD
Celera1247,872,140 - 247,979,623 (+)RGD
Sequence:
RefSeq Acc Id: XM_006231599   ⟹   XP_006231661
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21252,149,574 - 252,255,108 (+)NCBI
Rnor_6.01273,856,706 - 273,961,964 (+)NCBI
Rnor_5.01281,267,424 - 281,375,203 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006231600   ⟹   XP_006231662
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21252,147,341 - 252,255,108 (+)NCBI
Rnor_6.01273,854,195 - 273,961,964 (+)NCBI
Rnor_5.01281,267,424 - 281,375,203 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006231601   ⟹   XP_006231663
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21252,200,750 - 252,255,108 (+)NCBI
Rnor_6.01273,906,949 - 273,961,964 (+)NCBI
Rnor_5.01281,267,424 - 281,375,203 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006231602   ⟹   XP_006231664
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01273,910,830 - 273,961,964 (+)NCBI
Rnor_5.01281,267,424 - 281,375,203 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008760510   ⟹   XP_008758732
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21252,149,602 - 252,255,108 (+)NCBI
Rnor_6.01273,856,695 - 273,961,964 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017588809   ⟹   XP_017444298
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01273,907,765 - 273,961,964 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017588810   ⟹   XP_017444299
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01273,907,765 - 273,961,964 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039101448   ⟹   XP_038957376
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21252,148,037 - 252,255,108 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_113740   ⟸   NM_031552
- Peptide Label: isoform 2
- UniProtKB: Q62847 (UniProtKB/Swiss-Prot),   D3ZCH7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001157575   ⟸   NM_001164103
- Peptide Label: isoform 1
- UniProtKB: Q62847 (UniProtKB/Swiss-Prot),   G3V9D7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006231662   ⟸   XM_006231600
- Peptide Label: isoform X1
- UniProtKB: G3V9D7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006231661   ⟸   XM_006231599
- Peptide Label: isoform X1
- UniProtKB: G3V9D7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006231663   ⟸   XM_006231601
- Peptide Label: isoform X1
- UniProtKB: G3V9D7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006231664   ⟸   XM_006231602
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008758732   ⟸   XM_008760510
- Peptide Label: isoform X1
- UniProtKB: G3V9D7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017444298   ⟸   XM_017588809
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017444299   ⟸   XM_017588810
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSRNOP00000043399   ⟸   ENSRNOT00000044827
RefSeq Acc Id: ENSRNOP00000069717   ⟸   ENSRNOT00000086496
RefSeq Acc Id: ENSRNOP00000017600   ⟸   ENSRNOT00000017600
RefSeq Acc Id: XP_038957376   ⟸   XM_039101448
- Peptide Label: isoform X1
Protein Domains
Aldolase_II

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13690988
Promoter ID:EPDNEW_R1513
Type:initiation region
Name:Add3_1
Description:adducin 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01273,854,244 - 273,854,304EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Damaging Variants


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
1 281353933 281353934 G A snv LE/Stm (Illumina) (KNAW), LEC/Tj (KyushuU), GK/Ox (KNAW), LE/Stm (KyushuU), LE/Stm (SOLiD) (KNAW)
1 281370630 281370631 A C snv SBH/Ygl (KNAW), WKY/Gcrc (KNAW), WKY/N (KNAW), WKY/NCrl (KNAW), WKY/NHsd (KNAW), BUF/N (KNAW), FHH/EurMcwi (KNAW), FHL/EurMcwi (KNAW), LEW/Crl (KNAW), LEW/NCrl (KNAW), MNS/Gib (KNAW), WN/N (KNAW), SDLEF7/Barth (UDEL), BUF/MNa (KyushuU), HWY/Slc (KyushuU), ZF (KyushuU), BBDP/WorN (KNAW), MR/N (KNAW), FHL/EurMcwi (MCW), ZFDM (KyushuU), SBH/Ygl (MCW), FHH/EurMcwi (MCW)


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
1 273931066 273931067 G A snv MR/N (MCW), WKY/N (MCW), M520/N (MCW), F344/NRrrc (MCW), ACI/N (MCW), Buf/N (MCW), WN/N (MCW)
1 273931108 273931109 C T snv ACI/N (MCW)
1 273940712 273940713 G A snv GK/Ox (RGD), LE/Stm (RGD)
1 273947099 273947100 A G snv Buf/N (MCW), WKY/N (MCW), MR/N (MCW), WN/N (MCW)
1 273950932 273950933 A G snv MR/N (MCW), WKY/N (MCW), Buf/N (MCW), WN/N (MCW)
1 273957409 273957410 A C snv WKY/Gcrc (RGD), WKY/NCrl (RGD), SBH/Ygl (RGD), MNS/Gib (RGD), LEW/NCrlBR (RGD), LEW/Crl (RGD), FHH/EurMcwi (RGD), BBDP/Wor (RGD), FHL/EurMcwi (RGD), CDR, FHL/EurMcwi (MCW), WKY/NHsd (RGD), SBH/Ygl (MCW), FHH/EurMcwi (MCW)


Assembly: RGSC_v3.4

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
1 259352246 259352247 T G snv FHH/EurMcwi (MDC), LCR/2Mco (UMich), BUF/N (KNAW), HCR/2Mco (UMich), LCR/1Mco (UMich), MR/N (KNAW), WKY/N (KNAW), WN/N (KNAW), FHH/EurMcwi (MCW), FHL/EurMcwi (MCW), BBDP/WorN (ICL), FHH/EurMcwi (ICL), FHL/EurMcwi (ICL), LEW/Crl (ICL), LEW/NCrl (ICL), MNS/Gib (ICL), SBH/Ygl (ICL), WKY/Gcrc (ICL), WKY/NHsd (ICL), WKY/NCrl (ICL), HCR/1Mco (UMich)
1 259368943 259368944 C T snv GK/Ox (ICL), LE/Stm (ICL), LE/Stm (KNAW)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2043 AgrOrtholog
Ensembl Genes ENSRNOG00000012820 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000017600 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000043399 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000069717 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000017600 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000044827 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000086496 UniProtKB/TrEMBL
Gene3D-CATH 3.40.225.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ADD3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Aldolase_II/adducin_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Aldolase_II/adducin_N_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:25230 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 25230 ENTREZGENE
PANTHER PTHR10672:SF5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Aldolase_II UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Add3 PhenoGen
SMART Aldolase_II UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF53639 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JW28_RAT UniProtKB/TrEMBL
  ADDG_RAT UniProtKB/Swiss-Prot
  D3ZCH7 ENTREZGENE, UniProtKB/TrEMBL
  G3V9D7 ENTREZGENE, UniProtKB/TrEMBL
  Q62847 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-02 Add3  adducin 3  Add3  adducin 3 (gamma)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Add3  adducin 3 (gamma)    adducin 3, gamma  Name updated 1299863 APPROVED
2002-11-06 Add3  adducin 3, gamma    Adducin 3, gamma  Name updated 625702 APPROVED
2002-06-10 Add3  Adducin 3, gamma      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localized to the cytoskeleton 631726
gene_expression mRNA is detected in kidney 631734
gene_expression protein detected in renal proximal tubule epithelial cells 631726
gene_function binds phosphatidylserine 631734
gene_function binds and is a substrate for protein kinase C 631734
gene_homology has high similarity to the 3' end of beta adducin (Add2) 631734
gene_physical_interaction may form a heterodimer with alpha adducin (Add1) 631726
gene_product member of the adducin family 631726
gene_protein 80 and 90 kDa 631726