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Gene: ADD3 (adducin 3) Homo sapiens
Symbol: ADD3
Name: adducin 3
RGD ID: 735411
Description: Predicted to have actin filament binding activity; spectrin binding activity; and structural molecule activity. Predicted to be involved in actin filament bundle assembly and barbed-end actin filament capping. Localizes to plasma membrane. Implicated in hereditary spastic paraplegia 50.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ADDL; adducin 3 (gamma); adducin 3, gamma; adducin-like protein 70; CPSQ3; gamma-adducin
Mus musculus (house mouse) : Add3 (adducin 3 (gamma))  MGI  Alliance
Rattus norvegicus (Norway rat) : Add3 (adducin 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Add3 (adducin 3)
Pan paniscus (bonobo/pygmy chimpanzee) : ADD3 (adducin 3)
Canis lupus familiaris (dog) : ADD3 (adducin 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Add3 (adducin 3)
Sus scrofa (pig) : ADD3 (adducin 3)
Chlorocebus sabaeus (African green monkey) : ADD3 (adducin 3)
Heterocephalus glaber (naked mole-rat) : Add3 (adducin 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl10109,996,368 - 110,135,565 (+)EnsemblGRCh38hg38GRCh38
GRCh3810109,996,365 - 110,135,565 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3710111,765,627 - 111,895,323 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610111,755,716 - 111,885,313 (+)NCBINCBI36hg18NCBI36
Build 3410111,755,793 - 111,885,313NCBI
Celera10105,497,404 - 105,626,995 (+)NCBI
Cytogenetic Map10q25.1-q25.2NCBI
HuRef10105,396,619 - 105,526,176 (+)NCBIHuRef
CHM1_110112,037,774 - 112,177,067 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ADD3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735411
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.