(1->4)-beta-D-glucan multiple interactions ISO Cyp2c52-ps (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of CYP2C52-PS mRNA CTD PMID:36331819 (E,E)-germacrone decreases activity ISO CYP2C9 (Homo sapiens) 6480464 germacrone results in decreased activity of CYP2C9 protein CTD PMID:23850985 (R)-lipoic acid multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 Thioctic Acid inhibits the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid] CTD PMID:24120545 (S)-naringenin multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 naringenin inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Flurbiprofen] CTD PMID:21053930 (S)-naringenin decreases activity ISO CYP2C9 (Homo sapiens) 6480464 naringenin results in decreased activity of CYP2C9 protein CTD PMID:29753067 1,1,1-Trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane increases chemical synthesis ISO CYP2C18 (Homo sapiens) 6480464 CYP2C18 protein results in increased chemical synthesis of 1 more ... CTD PMID:9733665 1,1,1-Trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane increases chemical synthesis ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased chemical synthesis of 1 more ... CTD PMID:9733665 1,2-dichloroethene decreases expression EXP 6480464 1 and 2-dichloroethylene results in decreased expression of CYP2C11 protein CTD PMID:9493318 1,2-dichloroethene decreases activity EXP 6480464 1 and 2-dichloroethylene results in decreased activity of CYP2C11 protein CTD PMID:9493318 1,4-naphthoquinone increases abundance ISO CYP2C18 (Homo sapiens) 6480464 CYP2C18 protein results in increased abundance of 1 and 4-naphthoquinone CTD PMID:16243959 1,4-naphthoquinone increases abundance ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased abundance of 1 and 4-naphthoquinone CTD PMID:16243959 1-naphthol increases abundance ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased abundance of 1-naphthol CTD PMID:16243959 1-naphthyl isothiocyanate decreases expression EXP 6480464 1-Naphthylisothiocyanate results in decreased expression of CYP2C11 mRNA CTD PMID:25380136 and PMID:30723492 1-naphthyl isothiocyanate multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [1-Naphthylisothiocyanate co-treated with Cholic Acids] affects the expression of CYP2C9 mRNA CTD PMID:27344345 14,15-EET multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 Sulfaphenazole inhibits the reaction [CYP2C9 protein results in increased chemical synthesis of 14 more ... CTD PMID:12675279 14,15-EET increases chemical synthesis ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased chemical synthesis of 14 more ... CTD PMID:12675279 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of CYP2C11 protein CTD PMID:11731036 17alpha-ethynylestradiol increases hydroxylation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased hydroxylation of Ethinyl Estradiol CTD PMID:15304426 17alpha-ethynylestradiol decreases activity EXP 6480464 Ethinyl Estradiol results in decreased activity of CYP2C11 protein CTD PMID:11731036 and PMID:12029382 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of CYP2C11 mRNA CTD PMID:11553364 17beta-estradiol multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [ESR1 protein co-treated with MED25 protein co-treated with Estradiol] results in increased activity of CYP2C9 protein more ... CTD PMID:21768169 and PMID:27273787 17beta-estradiol increases activity ISO CYP2C9 (Homo sapiens) 6480464 Estradiol results in increased activity of CYP2C9 protein CTD PMID:22837389 2,2',4,4'-Tetrabromodiphenyl ether increases expression EXP 6480464 2 more ... CTD PMID:20056577 and PMID:31826744 2,3,7,8-tetrachlorodibenzodioxine decreases activity EXP 6480464 Tetrachlorodibenzodioxin results in decreased activity of CYP2C11 protein CTD PMID:16781091 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO CYP2C9 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in decreased expression of CYP2C9 mRNA CTD PMID:16985168 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO CYP2C18 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in decreased expression of CYP2C18 mRNA CTD PMID:16985168 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Cyp2c52-ps (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of CYP2C11 mRNA CTD PMID:18467041 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Cyp2c52-ps (Mus musculus) 6480464 alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP2C11 mRNA] CTD PMID:18467041 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of CYP2C mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of CYP2C11 mRNA CTD PMID:21215274 2,4,6-trinitrobenzenesulfonic acid multiple interactions EXP 6480464 gadolinium chloride inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP2C11 protein] more ... CTD PMID:18079364 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile multiple interactions EXP 6480464 Verapamil inhibits the reaction [Cyclosporine results in increased expression of CYP2C11 protein] CTD PMID:28899749 2-n-Propyl-4-pentenoic acid increases chemical synthesis ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased chemical synthesis of 2-propyl-4-pentenoic acid CTD PMID:16945988 2-nitroanisole increases oxidation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased oxidation of 2-nitroanisole CTD PMID:21218109 2-nitrophenol increases oxidation EXP 6480464 CYP2C11 protein results in increased oxidation of 2-nitrophenol CTD PMID:20027144 2-tert-butylhydroquinone increases expression ISO CYP2C9 (Homo sapiens) 6480464 2-tert-butylhydroquinone results in increased expression of CYP2C9 mRNA and 2-tert-butylhydroquinone results in increased expression of CYP2C9 protein CTD PMID:24830941 2-tert-butylhydroquinone multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [2-tert-butylhydroquinone results in increased expression of CYP2C9 mRNA] more ... CTD PMID:24830941 3,3',4,4',5-pentachlorobiphenyl decreases expression EXP 6480464 3 more ... CTD PMID:31820026 3,3',5-triiodo-L-thyronine multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 Triiodothyronine promotes the reaction [CYP2C9 protein results in increased metabolism of Coumarins] CTD PMID:14557374 3-methylcholanthrene multiple interactions EXP 6480464 Methylcholanthrene promotes the reaction [CYP2C11 protein results in increased oxidation of Toluene] CTD PMID:1994898 3-methylcholanthrene increases expression EXP 6480464 Methylcholanthrene results in increased expression of CYP2C11 mRNA CTD PMID:23273579 3-methylcholanthrene decreases expression EXP 6480464 Methylcholanthrene results in decreased expression of CYP2C11 mRNA CTD PMID:10476907 and PMID:22978700 3-oxo-5beta-cholanic acid multiple interactions EXP 6480464 [CYP2C11 protein results in increased metabolism of Lithocholic Acid] which results in increased chemical synthesis of 3-oxocholan-24-oic acid CTD PMID:18039809 4'-hydroxydiclofenac multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [[CYP2C9 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased hydroxylation of Diclofenac] which results in increased abundance of 4'-hydroxydiclofenac more ... CTD PMID:24104198 more ... 4'-hydroxydiclofenac increases chemical synthesis ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased chemical synthesis of 4'-hydroxydiclofenac CTD PMID:12401345 and PMID:15155557 4,4'-diaminodiphenylmethane decreases expression EXP 6480464 4 and 4'-diaminodiphenylmethane results in decreased expression of CYP2C11 mRNA CTD PMID:25380136 and PMID:30723492 4,4'-sulfonyldiphenol increases hydroxylation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased hydroxylation of bisphenol S CTD PMID:27213244 4,4'-sulfonyldiphenol multiple interactions ISO CYP2C18 (Homo sapiens) 6480464 [bisphenol S co-treated with Fulvestrant] results in increased methylation of CYP2C18 gene CTD PMID:31601247 4-[(1E)-1,2-diphenylbut-1-en-1-yl]phenol multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [CYP2C9 protein results in increased metabolism of 1-(4-hydroxyphenyl)-1 more ... CTD PMID:29285606 4-[(1E)-1,2-diphenylbut-1-en-1-yl]phenol increases activity ISO CYP2C9 (Homo sapiens) 6480464 1-(4-hydroxyphenyl)-1 and 2-diphenyl-1-butene results in increased activity of CYP2C9 protein CTD PMID:29285606 4-[(1E)-1,2-diphenylbut-1-en-1-yl]phenol increases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased metabolism of 1-(4-hydroxyphenyl)-1 and 2-diphenyl-1-butene CTD PMID:29285606 4-amino-5-chloro-N-[1-[3-(4-fluorophenoxy)propyl]-3-methoxy-4-piperidinyl]-2-methoxybenzamide decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Cisapride results in decreased activity of CYP2C9 protein CTD PMID:15306208 4-hydroxy-3-(2-hydroxy-3-oxo-1-phenylbutyl)-2H-chromen-2-one multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 10-hydroxywarfarin binds to and results in decreased activity of CYP2C9 protein more ... CTD PMID:20429590 more ... 4-hydroxy-3-[1-(4-hydroxyphenyl)-3-oxobutyl]-2H-chromen-2-one multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 4'-hydroxywarfarin binds to and results in decreased activity of CYP2C9 protein more ... CTD PMID:20429590 more ... 4-Hydroxy-N-desmethyltamoxifen decreases activity ISO CYP2C9 (Homo sapiens) 6480464 4-hydroxy-N-desmethyltamoxifen results in decreased activity of CYP2C9 protein CTD PMID:29285606 4-hydroxycyclophosphamide increases chemical synthesis ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased chemical synthesis of 4-hydroxycyclophosphamide CTD PMID:24819615 4-hydroxyphenytoin multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [CYP2C9 protein results in increased hydroxylation of Phenytoin] which results in increased abundance of hydroxyphenytoin and Miconazole inhibits the reaction [[CYP2C9 protein results in increased hydroxylation of Phenytoin] which results in increased abundance of hydroxyphenytoin] CTD PMID:33961833 4-hydroxytolbutamide increases chemical synthesis ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased chemical synthesis of 4'-hydroxytolbutamide and CYP2C9 protein results in increased chemical synthesis of hydroxymethyltolbutamide CTD PMID:15155557 and PMID:21915887 4-hydroxytolbutamide multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [CYP2C9 protein results in increased metabolism of Tolbutamide] which results in increased chemical synthesis of 4'-hydroxytolbutamide more ... CTD PMID:21915887 and PMID:32198085 4-Hydroxyvalproic acid increases chemical synthesis ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased chemical synthesis of 4-hydroxyvalproate CTD PMID:16945988 4-isopropylphenol increases glutathionylation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased glutathionylation of 4-isopropylphenol CTD PMID:23470418 4-methylimidazole multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 4-methylimidazole inhibits the reaction [CYP2C9 protein affects the metabolism of Diclofenac] CTD PMID:16081671 4-tert-Octylphenol increases response to substance ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 gene SNP results in increased susceptibility to 4-tert-octylphenol CTD PMID:23555028 5,7-dihydroxy-4'-methoxyflavone decreases activity EXP 6480464 acacetin results in decreased activity of CYP2C11 protein CTD PMID:32738202 5,7-dihydroxy-4'-methoxyflavone multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 acacetin inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Flurbiprofen] CTD PMID:21053930 5-aza-2'-deoxycytidine increases expression ISO Cyp2c52-ps (Mus musculus) 6480464 Decitabine results in increased expression of CYP2C18 mRNA CTD PMID:30503582 5-hydroxydiclofenac multiple interactions ISO CYP2C18 (Homo sapiens) 6480464 [CYP2C18 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 5-hydroxydiclofenac CTD PMID:24246759 5-Hydroxyflavone multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 5-hydroxyflavone inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Flurbiprofen] CTD PMID:21053930 5-Hydroxythalidomide increases metabolic processing ISO CYP2C18 (Homo sapiens) 6480464 CYP2C18 protein results in increased metabolism of 5-hydroxythalidomide CTD PMID:24350712 5-Hydroxyvalproic acid increases chemical synthesis ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased chemical synthesis of 5-hydroxyvalproate CTD PMID:16945988 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 Omeprazole inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Diclofenac] CTD PMID:15258107 5-methoxyindole decreases activity ISO CYP2C9 (Homo sapiens) 6480464 5-methoxyindole results in decreased activity of CYP2C9 protein CTD PMID:18420780 5-methyltryptamine decreases activity ISO CYP2C9 (Homo sapiens) 6480464 5-methyltryptamine analog results in decreased activity of CYP2C9 protein CTD PMID:26599973 5-methyltryptamine multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [5-methyltryptamine analog results in decreased activity of CYP2C9 protein] which results in decreased metabolism of Diclofenac CTD PMID:26599973 6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime increases expression ISO CYP2C9 (Homo sapiens) 6480464 6-(4-chlorophenyl)imidazo(2 more ... CTD PMID:21768169 6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 6-(4-chlorophenyl)imidazo(2 more ... CTD PMID:21768169 6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime increases expression ISO CYP2C18 (Homo sapiens) 6480464 6-(4-chlorophenyl)imidazo(2 more ... CTD PMID:28541575 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of CYP2C11 mRNA CTD PMID:24780913 7,12-dimethyltetraphene increases response to substance ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased susceptibility to 9 more ... CTD PMID:20507880 7-hydroxyflavone decreases activity ISO CYP2C9 (Homo sapiens) 6480464 7-hydroxyflavone results in decreased activity of CYP2C9 protein CTD PMID:29753067 7-hydroxyflavone multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 7-hydroxyflavone inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Flurbiprofen] CTD PMID:21053930 7-Hydroxywarfarin multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 10-hydroxywarfarin inhibits the reaction [[CYP2C9 protein results in increased hydroxylation of Warfarin] which results in increased chemical synthesis of 7-hydroxywarfarin] more ... CTD PMID:19408964 more ... 7-Hydroxywarfarin affects abundance ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 gene polymorphism affects the abundance of 7-hydroxywarfarin CTD PMID:25986145 7-Hydroxywarfarin decreases activity ISO CYP2C9 (Homo sapiens) 6480464 7-hydroxywarfarin results in decreased activity of CYP2C9 protein CTD PMID:20429590 7-Hydroxywarfarin increases chemical synthesis ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased chemical synthesis of 7-hydroxywarfarin CTD PMID:25986145 8'-apo-beta,psi-caroten-8'-al increases expression ISO CYP2C9 (Homo sapiens) 6480464 apocarotenal results in increased expression of CYP2C9 mRNA CTD PMID:17034753 8,9-EET multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 Sulfaphenazole inhibits the reaction [CYP2C9 protein results in increased chemical synthesis of 8 and 9-epoxyeicosatrienoic acid] CTD PMID:12675279 8,9-EET increases chemical synthesis ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased chemical synthesis of 8 and 9-epoxyeicosatrienoic acid CTD PMID:12675279 acenaphthylene increases oxidation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased oxidation of acenaphthylene CTD PMID:25642975 acenocoumarol affects response to substance ISO CYP2C18 (Homo sapiens) 6480464 CYP2C18 gene polymorphism affects the susceptibility to Acenocoumarol CTD PMID:19578179 acenocoumarol increases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased metabolism of Acenocoumarol CTD PMID:16878445 acenocoumarol affects metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein affects the metabolism of Acenocoumarol CTD PMID:11918509 acenocoumarol increases response to substance ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased susceptibility to Acenocoumarol CTD PMID:16869821 acenocoumarol affects response to substance ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 gene polymorphism affects the susceptibility to Acenocoumarol and CYP2C9 gene SNP affects the susceptibility to Acenocoumarol CTD PMID:15213846 more ... acetamide decreases expression EXP 6480464 acetamide results in decreased expression of CYP2C11 mRNA CTD PMID:31881176 acetone multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 Acetone promotes the reaction [CYP2C9 protein results in increased hydroxylation of Tolbutamide] CTD PMID:10611138 acetonitrile multiple interactions EXP 6480464 acetonitrile inhibits the reaction [CYP2C11 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin] CTD PMID:19858067 acetonitrile multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 acetonitrile promotes the reaction [CYP2C9 protein results in increased hydroxylation of Tolbutamide] CTD PMID:10611138 acetylsalicylic acid affects response to substance ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 polymorphism affects the susceptibility to Aspirin CTD PMID:21966608 aconitine increases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased metabolism of Aconitine CTD PMID:21277363 aconitine multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [Amiodarone results in decreased activity of CYP2C9 protein] which results in decreased chemical synthesis of Aconitine metabolite and [CYP2C9 protein results in increased metabolism of Aconitine] which results in increased chemical synthesis of 16-O-demethylaconitine CTD PMID:21277363 adefovir decreases activity ISO CYP2C9 (Homo sapiens) 6480464 adefovir results in decreased activity of CYP2C9 protein CTD PMID:17162464 adefovir pivoxil decreases activity ISO CYP2C9 (Homo sapiens) 6480464 adefovir dipivoxil results in decreased activity of CYP2C9 protein CTD PMID:17162464 afimoxifene increases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased metabolism of afimoxifene CTD PMID:29285606 aflatoxin B1 increases activity EXP 6480464 CYP2C11 protein results in increased activity of Aflatoxin B1 CTD PMID:11346484 aflatoxin B1 affects expression ISO CYP2C9 (Homo sapiens) 6480464 Aflatoxin B1 affects the expression of CYP2C9 protein CTD PMID:20106945 aflatoxin B1 decreases methylation ISO CYP2C9 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of CYP2C9 gene CTD PMID:27153756 aflatoxin B1 multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Aflatoxin B1 CTD PMID:23397584 aflatoxin B1 decreases expression ISO CYP2C9 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased expression of CYP2C9 mRNA CTD PMID:27153756 aflatoxin B1 decreases expression ISO CYP2C18 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased expression of CYP2C18 mRNA CTD PMID:22100608 aflatoxin B1 affects expression ISO CYP2C18 (Homo sapiens) 6480464 Aflatoxin B1 affects the expression of CYP2C18 protein CTD PMID:20106945 aflatoxin B1 decreases methylation ISO CYP2C18 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of CYP2C18 gene CTD PMID:27153756 aflatoxin B1 increases expression ISO CYP2C9 (Homo sapiens) 6480464 Aflatoxin B1 results in increased expression of CYP2C9 mRNA CTD PMID:21994236 alizarin decreases activity ISO CYP2C9 (Homo sapiens) 6480464 alizarin results in decreased activity of CYP2C9 protein CTD PMID:33438235 all-trans-4-hydroxyretinoic acid increases chemical synthesis ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased chemical synthesis of 4-hydroxyretinoic acid CTD PMID:10874126 all-trans-4-oxoretinoic acid increases chemical synthesis ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased chemical synthesis of 4-oxoretinoic acid CTD PMID:10874126 all-trans-retinoic acid decreases expression ISO CYP2C18 (Homo sapiens) 6480464 Tretinoin results in decreased expression of CYP2C18 mRNA CTD PMID:16985168 all-trans-retinoic acid decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Tretinoin results in decreased activity of CYP2C9 protein CTD PMID:18420780 all-trans-retinoic acid decreases expression ISO CYP2C9 (Homo sapiens) 6480464 Tretinoin results in decreased expression of CYP2C9 mRNA CTD PMID:16985168 all-trans-retinoic acid increases hydroxylation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased hydroxylation of Tretinoin CTD PMID:10874126 all-trans-retinol multiple interactions EXP 6480464 GH1 protein promotes the reaction [Vitamin A affects the expression of and affects the activity of CYP2C11 protein] and Vitamin A affects the expression of and affects the activity of CYP2C11 protein CTD PMID:15963505 Aloe emodin decreases activity ISO CYP2C9 (Homo sapiens) 6480464 aloe emodin results in decreased activity of CYP2C9 protein CTD PMID:33438235 alpha-hexachlorocyclohexane multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased expression of CYP2C11 mRNA and [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased expression of CYP2C11 protein CTD PMID:16246485 alpha-linolenic acid multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased metabolism of [alpha-Linolenic Acid co-treated with NADP] CTD PMID:16978661 alpha-linolenic acid decreases activity ISO CYP2C9 (Homo sapiens) 6480464 alpha-Linolenic Acid results in decreased activity of CYP2C9 protein CTD PMID:16978661 alpha-naphthoflavone multiple interactions ISO Cyp2c52-ps (Mus musculus) 6480464 alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP2C11 mRNA] CTD PMID:18467041 alpha-naphthoflavone multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 alpha-naphthoflavone inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Flurbiprofen] CTD PMID:21053930 amiodarone decreases expression EXP 6480464 Amiodarone results in decreased expression of CYP2C11 mRNA CTD PMID:32084307 amiodarone multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [Amiodarone results in decreased activity of CYP2C9 protein] which results in decreased chemical synthesis of 16-O-demethylaconitine more ... CTD PMID:14557374 more ... amiodarone decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Amiodarone results in decreased activity of CYP2C9 protein CTD PMID:16449812 amiodarone decreases response to substance ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in decreased susceptibility to Amiodarone CTD PMID:26477383 amiodarone increases expression ISO CYP2C9 (Homo sapiens) 6480464 Amiodarone results in increased expression of CYP2C9 mRNA CTD PMID:36586010 amiodarone decreases response to substance ISO CYP2C18 (Homo sapiens) 6480464 CYP2C18 protein results in decreased susceptibility to Amiodarone CTD PMID:26477383 amitriptyline multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Amitriptyline CTD PMID:23397584 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of CYP2C mRNA CTD PMID:16483693 amodiaquine multiple interactions ISO CYP2C18 (Homo sapiens) 6480464 [CYP2C18 protein results in increased metabolism of Amodiaquine] which results in increased abundance of desethylamodiaquine CTD PMID:31629065 amodiaquine decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Amodiaquine results in decreased activity of CYP2C9 protein CTD PMID:11124226 amodiaquine increases metabolic processing ISO CYP2C18 (Homo sapiens) 6480464 CYP2C18 protein results in increased metabolism of Amodiaquine CTD PMID:31629065 ampicillin multiple interactions EXP 6480464 [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP2C11 mRNA CTD PMID:30545405 Ancriviroc decreases ethylation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in decreased ethylation of Ancriviroc CTD PMID:16012074 Ancriviroc affects metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein affects the metabolism of Ancriviroc CTD PMID:16012074 andrographolide decreases expression EXP 6480464 andrographolide results in decreased expression of CYP2C11 mRNA and andrographolide results in decreased expression of CYP2C11 protein CTD PMID:19041297 andrographolide decreases expression ISO CYP2C9 (Homo sapiens) 6480464 andrographolide results in decreased expression of CYP2C9 mRNA CTD PMID:19041297 anthocyanin increases expression EXP 6480464 Anthocyanins results in increased expression of CYP2C mRNA CTD PMID:18803703 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 pyrazolanthrone inhibits the reaction [2-tert-butylhydroquinone results in increased expression of CYP2C9 mRNA] CTD PMID:24830941 anthracene-1,8,9-triol decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Anthralin results in decreased activity of CYP2C9 protein CTD PMID:33438235 apigenin multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 Apigenin inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Flurbiprofen] CTD PMID:21053930 apigenin decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Apigenin results in decreased activity of CYP2C9 protein CTD PMID:29753067 arachidonic acid decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Arachidonic Acid results in decreased activity of CYP2C9 protein CTD PMID:16978661 arachidonic acid increases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased metabolism of Arachidonic Acid CTD PMID:12675279 arachidonic acid multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased metabolism of [Arachidonic Acid co-treated with NADP] and Sulfaphenazole inhibits the reaction [CYP2C9 protein results in increased metabolism of Arachidonic Acid] CTD PMID:12675279 and PMID:16978661 aristolochic acid A multiple interactions EXP 6480464 [aristolochic acid I co-treated with 1-phenylazo-2-naphthol] results in decreased activity of CYP2C11 protein more ... CTD PMID:21362632 more ... aristolochic acid A increases expression ISO CYP2C9 (Homo sapiens) 6480464 aristolochic acid I results in increased expression of CYP2C9 mRNA CTD PMID:33212167 aristolochic acid A increases expression ISO CYP2C18 (Homo sapiens) 6480464 aristolochic acid I results in increased expression of CYP2C18 mRNA CTD PMID:33212167 Aroclor 1254 increases expression EXP 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of CYP2C mRNA CTD PMID:18178546 arsane multiple interactions ISO CYP2C18 (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of CYP2C18 mRNA CTD PMID:32525701 arsenic atom multiple interactions ISO CYP2C18 (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of CYP2C18 mRNA CTD PMID:32525701 atazanavir sulfate multiple interactions ISO CYP2C18 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of CYP2C18 mRNA CTD PMID:33819548 atazanavir sulfate multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of CYP2C9 mRNA CTD PMID:33819548 atrazine decreases activity EXP 6480464 Atrazine results in decreased activity of CYP2C11 protein CTD PMID:9711812 Auriculasin increases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased metabolism of auriculasin CTD PMID:31515991 Auriculasin decreases activity ISO CYP2C9 (Homo sapiens) 6480464 auriculasin results in decreased activity of CYP2C9 protein CTD PMID:31515991 Auriculasin multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 Sulfaphenazole inhibits the reaction [CYP2C9 protein results in increased metabolism of auriculasin] CTD PMID:31515991 Avasimibe decreases activity ISO CYP2C9 (Homo sapiens) 6480464 avasimibe results in decreased activity of CYP2C9 protein CTD PMID:15333513 Avasimibe multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 avasimibe results in increased activity of and results in increased expression of CYP2C9 protein and avasimibe results in increased expression of and results in increased activity of CYP2C9 protein CTD PMID:15333513 and PMID:19202563 baicalein multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 baicalein inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Flurbiprofen] CTD PMID:21053930 baicalein decreases activity ISO CYP2C9 (Homo sapiens) 6480464 baicalein results in decreased activity of CYP2C9 protein CTD PMID:29753067 barnidipine decreases activity ISO CYP2C9 (Homo sapiens) 6480464 mepirodipine results in decreased activity of CYP2C9 protein CTD PMID:10805063 benfuracarb increases oxidation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased oxidation of benfuracarb CTD PMID:24016712 benidipine decreases activity ISO CYP2C9 (Homo sapiens) 6480464 benidipine results in decreased activity of CYP2C9 protein CTD PMID:10805063 and PMID:27732883 benzbromarone affects metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein affects the metabolism of Benzbromarone CTD PMID:18020424 and PMID:21321060 benzbromarone affects binding ISO CYP2C9 (Homo sapiens) 6480464 Benzbromarone binds to CYP2C9 protein CTD PMID:12814975 benzbromarone multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 Benzbromarone analog binds to and results in decreased activity of CYP2C9 protein more ... CTD PMID:10613612 more ... benzene decreases expression EXP 6480464 Benzene results in decreased expression of CYP2C11 protein CTD PMID:8135039 benzene multiple interactions EXP 6480464 CYP2C11 protein affects the reaction [Benzene results in increased metabolism of Toluene] CTD PMID:8620572 benzo[a]pyrene affects methylation ISO CYP2C18 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of CYP2C18 promoter CTD PMID:27901495 benzo[a]pyrene decreases expression ISO CYP2C9 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of CYP2C9 mRNA CTD PMID:32234424 benzo[a]pyrene decreases expression ISO CYP2C18 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of CYP2C18 mRNA CTD PMID:32234424 benzo[a]pyrene decreases methylation ISO CYP2C18 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased methylation of CYP2C18 exon CTD PMID:27901495 Benzo[a]pyrene-7,8-oxide multiple interactions EXP 6480464 CYP2C11 protein promotes the reaction [EPHX1 protein affects the hydrolysis of benzo(a)pyrene 7 and 8-oxide] CTD PMID:12051674 benzophenone increases expression EXP 6480464 benzophenone results in increased expression of CYP2C11 mRNA CTD PMID:14613717 beta-carotene increases expression ISO CYP2C9 (Homo sapiens) 6480464 beta Carotene results in increased expression of CYP2C9 mRNA CTD PMID:17034753 beta-naphthoflavone multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CYP2C mRNA and [Phenobarbital co-treated with beta-Naphthoflavone] results in decreased expression of CYP2C11 protein CTD PMID:18164116 and PMID:30842367 beta-naphthoflavone multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 beta-Naphthoflavone inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Flurbiprofen] CTD PMID:21053930 beta-naphthoflavone decreases expression ISO CYP2C18 (Homo sapiens) 6480464 beta-Naphthoflavone results in decreased expression of CYP2C18 mRNA CTD PMID:16985168 beta-naphthoflavone decreases expression ISO CYP2C9 (Homo sapiens) 6480464 beta-Naphthoflavone results in decreased expression of CYP2C9 mRNA CTD PMID:16985168 and PMID:33263786 bilirubin IXalpha multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 IL1B protein inhibits the reaction [Bilirubin results in increased expression of CYP2C9 mRNA] CTD PMID:15382119 bilirubin IXalpha increases expression ISO CYP2C9 (Homo sapiens) 6480464 Bilirubin results in increased expression of CYP2C9 mRNA CTD PMID:15382119 biochanin A decreases activity ISO CYP2C9 (Homo sapiens) 6480464 biochanin A results in decreased activity of CYP2C9 protein CTD PMID:26278343 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of CYP2C11 mRNA CTD PMID:32145629 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of CYP2C9 mRNA CTD PMID:25181051 bisphenol A increases hydroxylation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased hydroxylation of bisphenol A and CYP2C9 protein results in increased hydroxylation of bisphenol A metabolite CTD PMID:23470418 bisphenol A increases glutathionylation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased glutathionylation of bisphenol A and CYP2C9 protein results in increased glutathionylation of bisphenol A metabolite CTD PMID:23470418 bisphenol A multiple interactions ISO CYP2C18 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of CYP2C18 gene CTD PMID:31601247 bisphenol A multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [ESR1 protein co-treated with MED25 protein co-treated with bisphenol A] results in increased activity of CYP2C9 protein and [ESR1 protein co-treated with MED25 protein co-treated with bisphenol A] results in increased expression of CYP2C9 mRNA CTD PMID:27273787 bisphenol A increases methylation ISO CYP2C18 (Homo sapiens) 6480464 bisphenol A results in increased methylation of CYP2C18 gene CTD PMID:31601247 bisphenol A increases expression ISO CYP2C9 (Homo sapiens) 6480464 bisphenol A results in increased expression of CYP2C9 mRNA CTD PMID:26196221 bisphenol F increases hydroxylation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased hydroxylation of 4 and 4'-bisphenol F CTD PMID:23470418 bisphenol F increases glutathionylation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased glutathionylation of 4 more ... CTD PMID:23470418 bortezomib affects metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein affects the metabolism of Bortezomib CTD PMID:15764713 bromfenac increases hydroxylation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased hydroxylation of bromfenac CTD PMID:31815452 bromfenac multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 Acetylcysteine affects the reaction [CYP2C9 protein results in increased hydroxylation of bromfenac] and Glutathione affects the reaction [CYP2C9 protein results in increased hydroxylation of bromfenac] CTD PMID:31815452 Bufuralol increases hydroxylation EXP 6480464 CYP2C11 protein results in increased hydroxylation of bufuralol CTD PMID:11911841 Bufuralol increases hydroxylation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased hydroxylation of bufuralol CTD PMID:9429232 busulfan multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [GSTM1 protein co-treated with CYP2C9 protein] results in increased susceptibility to [Busulfan co-treated with Cyclophosphamide] CTD PMID:28744217 butanal increases expression ISO CYP2C18 (Homo sapiens) 6480464 butyraldehyde results in increased expression of CYP2C18 mRNA CTD PMID:26079696 butanal increases expression ISO CYP2C9 (Homo sapiens) 6480464 butyraldehyde results in increased expression of CYP2C9 mRNA CTD PMID:26079696 Butylbenzyl phthalate decreases activity EXP 6480464 butylbenzyl phthalate results in decreased activity of CYP2C11 protein CTD PMID:27432241 Butylparaben decreases activity EXP 6480464 butylparaben results in decreased activity of CYP2C11 protein CTD PMID:27432241 butyric acid multiple interactions EXP 6480464 Butyric Acid inhibits the reaction [[Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of CYP2C9 mRNA] CTD PMID:37414240 butyric acid multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [Butyric Acid co-treated with Sulfaphenazole] inhibits the reaction [Oxalic Acid results in increased expression of CYP2C9 mRNA] and Butyric Acid inhibits the reaction [Oxalic Acid results in increased expression of CYP2C9 mRNA] CTD PMID:37414240 C.I. Natural Red 20 decreases activity EXP 6480464 shikonin results in decreased activity of CYP2C11 protein CTD PMID:28941798 C.I. Natural Red 20 decreases activity ISO CYP2C9 (Homo sapiens) 6480464 shikonin results in decreased activity of CYP2C9 protein CTD PMID:28941798 cadmium atom increases expression ISO CYP2C9 (Homo sapiens) 6480464 Cadmium results in increased expression of CYP2C9 protein CTD PMID:11551516 cafestol multiple interactions EXP 6480464 [cafestol co-treated with kahweol] results in decreased expression of CYP2C11 and [cafestol co-treated with kahweol] results in decreased expression of CYP2C11 protein CTD PMID:11346484 and PMID:9744531 calciol increases expression ISO CYP2C9 (Homo sapiens) 6480464 Cholecalciferol metabolite results in increased expression of CYP2C9 CTD PMID:11991950 calciol decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Cholecalciferol results in decreased activity of CYP2C9 protein CTD PMID:18420780 calcium oxalate multiple interactions EXP 6480464 [Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of CYP2C9 mRNA and Butyric Acid inhibits the reaction [[Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of CYP2C9 mRNA] CTD PMID:37414240 cannabidiol decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Cannabidiol results in decreased activity of CYP2C9 protein CTD PMID:24667653 capsaicin decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Capsaicin results in decreased activity of CYP2C9 protein CTD PMID:22375877 carbamazepine increases expression ISO CYP2C9 (Homo sapiens) 6480464 Carbamazepine results in increased expression of CYP2C9 mRNA CTD PMID:17112801 carbamazepine increases activity ISO CYP2C9 (Homo sapiens) 6480464 Carbamazepine results in increased activity of CYP2C9 protein CTD PMID:19202563 carbamazepine multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Carbamazepine CTD PMID:23397584 carbamazepine affects metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein affects the metabolism of Carbamazepine CTD PMID:15286053 carfentanil increases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased metabolism of carfentanil CTD PMID:33652071 Carnosol decreases activity ISO CYP2C9 (Homo sapiens) 6480464 carnosol results in decreased activity of CYP2C9 protein CTD PMID:34592323 carvedilol increases metabolic processing EXP 6480464 CYP2C11 protein results in increased metabolism of carvedilol CTD PMID:29415952 cefaloridine decreases expression EXP 6480464 Cephaloridine results in decreased expression of CYP2C mRNA CTD PMID:18500788 celecoxib increases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased metabolism of Celecoxib CTD PMID:17681167 and PMID:19082874 CGP 52608 multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to CYP2C9 gene] CTD PMID:28238834 chenodeoxycholic acid decreases activity EXP 6480464 Chenodeoxycholic Acid results in decreased activity of CYP2C11 protein CTD PMID:8889968 chenodeoxycholic acid multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in decreased expression of CYP2C9 mRNA more ... CTD PMID:33819548 chenodeoxycholic acid multiple interactions ISO CYP2C18 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of CYP2C18 mRNA more ... CTD PMID:33819548 chlorpromazine decreases expression EXP 6480464 Chlorpromazine results in decreased expression of CYP2C mRNA and Chlorpromazine results in decreased expression of CYP2C11 mRNA CTD PMID:18246545 chlorpromazine decreases response to substance ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in decreased susceptibility to Chlorpromazine CTD PMID:26477383 chlorpromazine decreases response to substance ISO CYP2C18 (Homo sapiens) 6480464 CYP2C18 protein results in decreased susceptibility to Chlorpromazine CTD PMID:26477383 chlorpromazine multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Chlorpromazine CTD PMID:23397584 chlorpromazine decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Chlorpromazine results in decreased activity of CYP2C9 protein CTD PMID:15135088 chlorpyrifos affects metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein affects the metabolism of Chlorpyrifos CTD PMID:16190164 chlorzoxazone affects metabolic processing EXP 6480464 CYP2C11 protein affects the metabolism of Chlorzoxazone CTD PMID:15879494 cholic acid decreases activity EXP 6480464 Cholic Acid results in decreased activity of CYP2C11 protein CTD PMID:8889968 choline multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency] results in decreased expression of CYP2C11 mRNA and [Methionine deficiency co-treated with Choline deficiency] results in decreased expression of CYP2C11 protein CTD PMID:24403518 chrysin multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 chrysin inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Flurbiprofen] CTD PMID:21053930 chrysophanol decreases activity ISO CYP2C9 (Homo sapiens) 6480464 chrysophanic acid results in decreased activity of CYP2C9 protein CTD PMID:27633141 cimetidine multiple interactions EXP 6480464 Cimetidine inhibits the reaction [CYP2C11 protein results in increased glutathionylation of lamotrigine] CTD PMID:19961160 cimetidine decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Cimetidine results in decreased activity of CYP2C9 protein CTD PMID:19909766 cimetidine multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 styrofoam analog promotes the reaction [Cimetidine results in decreased activity of CYP2C9 protein] CTD PMID:19909766 ciprofloxacin decreases expression EXP 6480464 Ciprofloxacin results in decreased expression of CYP2C11 mRNA CTD PMID:12621481 cisapride decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Cisapride results in decreased activity of CYP2C9 protein CTD PMID:15306208 cisplatin decreases expression EXP 6480464 Cisplatin results in decreased expression of CYP2C mRNA CTD PMID:22023808 cisplatin affects response to substance ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein affects the susceptibility to Cisplatin CTD PMID:16217747 clofibric acid multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CYP2C mRNA more ... CTD PMID:15788368 and PMID:17602206 clofibric acid increases expression ISO CYP2C9 (Homo sapiens) 6480464 Clofibric Acid results in increased expression of CYP2C9 mRNA CTD PMID:15802389 clofibric acid decreases expression EXP 6480464 Clofibric Acid results in decreased expression of CYP2C11 mRNA CTD PMID:15788368 clopidogrel decreases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 gene SNP results in decreased metabolism of Clopidogrel CTD PMID:17900275 clopidogrel multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 gene affects the reaction [CYP2C19 gene affects the susceptibility to Clopidogrel] and CYP2C9 protein results in increased oxidation of and results in increased cleavage of Clopidogrel metabolite CTD PMID:19170597 more ... clopidogrel affects response to substance ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 gene SNP affects the susceptibility to Clopidogrel CTD PMID:17900275 clothianidin multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [clothianidin co-treated with thiacloprid] results in increased expression of CYP2C9 protein CTD PMID:32201337 clotrimazole multiple interactions EXP 6480464 Clotrimazole inhibits the reaction [CYP2C11 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin] CTD PMID:19858067 clotrimazole multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 Clotrimazole inhibits the reaction [CYP2C9 protein affects the metabolism of Diclofenac] and Clotrimazole results in increased activity of and results in increased expression of CYP2C9 protein CTD PMID:16081671 and PMID:19202563 clotrimazole affects binding ISO CYP2C9 (Homo sapiens) 6480464 Clotrimazole binds to CYP2C9 protein and Clotrimazole binds to CYP2C9 protein alternative form CTD PMID:29621561 clotrimazole decreases expression EXP 6480464 Clotrimazole results in decreased expression of CYP2C11 protein CTD PMID:7986207 clozapine multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [Clozapine results in decreased activity of CYP2C9 protein] which results in increased susceptibility to Phenytoin and [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Clozapine CTD PMID:17961958 and PMID:23397584 clozapine increases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased metabolism of Clozapine CTD PMID:18809730 cocaine decreases expression ISO CYP2C9 (Homo sapiens) 6480464 Cocaine results in decreased expression of CYP2C9 mRNA and Cocaine results in decreased expression of CYP2C9 protein CTD PMID:16188404 copper atom decreases expression EXP 6480464 Copper results in decreased expression of CYP2C mRNA CTD PMID:22465980 copper atom multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [CYP2C9 protein co-treated with Copper] results in increased activity of Eugenol CTD PMID:15576237 copper(0) decreases expression EXP 6480464 Copper results in decreased expression of CYP2C mRNA CTD PMID:22465980 copper(0) multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [CYP2C9 protein co-treated with Copper] results in increased activity of Eugenol CTD PMID:15576237 corticosterone increases expression EXP 6480464 Corticosterone results in increased expression of CYP2C11 mRNA CTD PMID:35301062 corticosterone increases expression ISO CYP2C9 (Homo sapiens) 6480464 Corticosterone results in increased expression of CYP2C9 mRNA CTD PMID:35301062 coumarin decreases expression EXP 6480464 coumarin results in decreased expression of CYP2C mRNA CTD PMID:18480146 coumarin affects response to substance ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein polymorphism affects the susceptibility to coumarin CTD PMID:23582453 coumarin affects metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein polymorphism affects the metabolism of coumarin CTD PMID:17849045 coumarins multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 Amiodarone promotes the reaction [CYP2C9 protein results in increased metabolism of Coumarins] more ... CTD PMID:14557374 coumarins increases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased metabolism of Coumarins CTD PMID:14557374 crocidolite asbestos increases expression ISO CYP2C18 (Homo sapiens) 6480464 Asbestos and Crocidolite results in increased expression of CYP2C18 mRNA CTD PMID:25351596 cumene hydroperoxide affects oxidation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein affects the oxidation of cumene hydroperoxide CTD PMID:17478480 curcumin multiple interactions EXP 6480464 Curcumin inhibits the reaction [Carbon Tetrachloride results in decreased activity of CYP2C9 protein] CTD PMID:16288784 cyclophosphamide increases expression EXP 6480464 Cyclophosphamide results in increased expression of CYP2C11 mRNA CTD PMID:16019949 cyclophosphamide multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [GSTM1 protein co-treated with CYP2C9 protein] results in increased susceptibility to [Busulfan co-treated with Cyclophosphamide] and Sulfaphenazole inhibits the reaction [CYP2C9 protein results in increased susceptibility to Cyclophosphamide] CTD PMID:10991840 and PMID:28744217 cyclophosphamide increases response to substance ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased susceptibility to Cyclophosphamide CTD PMID:10991840 cyclophosphamide increases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased metabolism of Cyclophosphamide CTD PMID:11377097 and PMID:24819615 cyclophosphamide increases response to substance ISO CYP2C18 (Homo sapiens) 6480464 CYP2C18 results in increased susceptibility to Cyclophosphamide CTD PMID:9766669 cyclophosphamide increases activity ISO CYP2C18 (Homo sapiens) 6480464 CYP2C18 results in increased activity of Cyclophosphamide CTD PMID:9241661 cyclophosphamide increases activity ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 results in increased activity of Cyclophosphamide CTD PMID:9241661 cyclophosphamide multiple interactions ISO CYP2C18 (Homo sapiens) 6480464 POR promotes the reaction [CYP2C18 results in increased susceptibility to Cyclophosphamide] CTD PMID:9766669 cyclophosphamide increases metabolic processing EXP 6480464 CYP2C11 results in increased metabolism of Cyclophosphamide CTD PMID:20566340 cyclosporin A increases expression EXP 6480464 Cyclosporine results in increased expression of CYP2C11 protein CTD PMID:28899749 cyclosporin A multiple interactions ISO CYP2C18 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Cyclosporine] results in decreased expression of CYP2C18 mRNA CTD PMID:33819548 cyclosporin A decreases expression ISO CYP2C9 (Homo sapiens) 6480464 Cyclosporine results in decreased expression of CYP2C9 mRNA CTD PMID:20106945 and PMID:27989131 cyclosporin A decreases expression ISO CYP2C18 (Homo sapiens) 6480464 Cyclosporine results in decreased expression of CYP2C18 mRNA CTD PMID:20106945 cyclosporin A multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Cyclosporine] results in decreased expression of CYP2C9 mRNA CTD PMID:33819548 cyclosporin A multiple interactions EXP 6480464 Nifedipine promotes the reaction [Cyclosporine results in increased expression of CYP2C11 protein] and Verapamil inhibits the reaction [Cyclosporine results in increased expression of CYP2C11 protein] CTD PMID:28899749 cylindrospermopsin decreases activity ISO CYP2C9 (Homo sapiens) 6480464 cylindrospermopsin results in decreased activity of CYP2C9 protein CTD PMID:30905859 cypermethrin increases expression ISO CYP2C9 (Homo sapiens) 6480464 cypermethrin results in increased expression of CYP2C9 mRNA CTD PMID:22310298 cypermethrin decreases activity ISO CYP2C9 (Homo sapiens) 6480464 cypermethrin results in decreased activity of CYP2C9 protein CTD PMID:18420780 cyproconazole affects binding ISO CYP2C9 (Homo sapiens) 6480464 cyproconazole binds to CYP2C9 protein alternative form CTD PMID:29621561 cyproconazole decreases activity ISO CYP2C9 (Homo sapiens) 6480464 cyproconazole results in decreased activity of CYP2C9 protein CTD PMID:21251949 dabrafenib decreases activity ISO CYP2C9 (Homo sapiens) 6480464 dabrafenib results in decreased activity of CYP2C9 protein CTD PMID:34780725 daidzein decreases activity ISO CYP2C9 (Homo sapiens) 6480464 daidzein results in decreased activity of CYP2C9 protein CTD PMID:18420780 and PMID:29753067 dapsone affects metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein affects the metabolism of Dapsone CTD PMID:12920490 dapsone multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 Dapsone promotes the reaction [CYP2C9 protein polymorphism results in decreased methylation of Naproxen] more ... CTD PMID:15130760 dapsone decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Dapsone results in decreased activity of CYP2C9 protein CTD PMID:11124226 dehydroepiandrosterone sulfate multiple interactions EXP 6480464 [Dehydroepiandrosterone Sulfate co-treated with Phenobarbital] results in increased expression of CYP2C11 protein CTD PMID:25786523 delavirdine decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Delavirdine results in decreased activity of CYP2C9 protein CTD PMID:11225565 deoxycholic acid decreases expression EXP 6480464 Deoxycholic Acid results in decreased expression of CYP2C11 protein CTD PMID:10453939 deoxycholic acid multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in decreased expression of CYP2C9 mRNA more ... CTD PMID:33819548 deoxycholic acid multiple interactions ISO CYP2C18 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of CYP2C18 mRNA more ... CTD PMID:33819548 deoxycholic acid decreases activity EXP 6480464 Deoxycholic Acid results in decreased activity of CYP2C11 protein CTD PMID:8889968 deoxycholic acid multiple interactions EXP 6480464 Ursodeoxycholic Acid inhibits the reaction [Deoxycholic Acid results in decreased expression of CYP2C11 protein] CTD PMID:10453939 desipramine decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Desipramine results in decreased activity of CYP2C9 protein CTD PMID:15135088 dexamethasone increases expression EXP 6480464 Dexamethasone results in increased expression of CYP2C11 and Dexamethasone results in increased expression of CYP2C11 protein CTD PMID:15890479 and PMID:19041297 dexamethasone increases expression ISO CYP2C9 (Homo sapiens) 6480464 Dexamethasone results in increased expression of CYP2C9 mRNA CTD PMID:15802389 dexamethasone multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 Dexamethasone results in increased expression of and results in increased activity of CYP2C9 protein CTD PMID:15802389 dexamethasone increases activity ISO CYP2C9 (Homo sapiens) 6480464 Dexamethasone results in increased activity of CYP2C9 protein CTD PMID:19202563 dexamethasone affects expression EXP 6480464 Dexamethasone affects the expression of CYP2C mRNA CTD PMID:15102944 diarylheptanoid decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Diarylheptanoids results in decreased activity of CYP2C9 protein CTD PMID:23850985 diazinon multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased metabolism of and results in increased activity of Diazinon CTD PMID:11708902 dibenz[a,h]anthracene increases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased metabolism of 1 more ... CTD PMID:8638931 dibenz[a,h]anthracene multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [CYP2C9 protein results in increased metabolism of 1 more ... CTD PMID:8638931 dibutyl phthalate decreases activity EXP 6480464 Dibutyl Phthalate results in decreased activity of CYP2C11 protein CTD PMID:27432241 dichlorine multiple interactions EXP 6480464 [Ozone co-treated with Chlorine] affects the expression of CYP2C mRNA CTD PMID:18636392 dichlorine decreases expression EXP 6480464 Chlorine results in decreased expression of CYP2C mRNA CTD PMID:18636392 diclofenac decreases hydroxylation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 gene polymorphism results in decreased hydroxylation of Diclofenac CTD PMID:11455026 diclofenac increases oxidation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased oxidation of Diclofenac CTD PMID:17478480 diclofenac decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Diclofenac results in decreased activity of CYP2C9 protein CTD PMID:15135088 diclofenac affects hydrolysis ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 gene polymorphism affects the hydrolysis of Diclofenac CTD PMID:9698079 diclofenac multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 1-aminobenzotriazole inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Diclofenac] more ... CTD PMID:12569440 more ... diclofenac increases activity ISO CYP2C9 (Homo sapiens) 6480464 Diclofenac results in increased activity of CYP2C9 protein CTD PMID:15802386 diclofenac affects metabolic processing EXP 6480464 CYP2C9 protein affects the metabolism of Diclofenac CTD PMID:15801540 diclofenac affects binding ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein binds to Diclofenac CTD PMID:15039296 diclofenac affects metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein affects the metabolism of Diclofenac CTD PMID:15801540 and PMID:16081671 diclofenac increases hydrolysis ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased hydrolysis of Diclofenac CTD PMID:9698079 diclofenac increases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 mRNA results in increased metabolism of Diclofenac and CYP2C9 protein results in increased metabolism of Diclofenac CTD PMID:12401345 more ... diclofenac increases hydroxylation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased hydroxylation of Diclofenac CTD PMID:10975605 more ... diclofenamide multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 Dichlorphenamide promotes the reaction [CYP2C9 protein results in increased metabolism of Coumarins] CTD PMID:14557374 diethyl phthalate decreases activity EXP 6480464 diethyl phthalate results in decreased activity of CYP2C11 protein CTD PMID:27432241 difenoconazole affects binding ISO CYP2C9 (Homo sapiens) 6480464 difenoconazole binds to CYP2C9 protein and difenoconazole binds to CYP2C9 protein alternative form CTD PMID:29621561 dihydrocapsaicin decreases activity ISO CYP2C9 (Homo sapiens) 6480464 dihydrocapsaicin results in decreased activity of CYP2C9 protein CTD PMID:22375877 dihydroergotamine decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Dihydroergotamine results in decreased activity of CYP2C9 protein CTD PMID:18420780 dimemorfan increases oxidation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased oxidation of dimemorfan CTD PMID:19593786 dimethyl sulfoxide multiple interactions EXP 6480464 Dimethyl Sulfoxide inhibits the reaction [CYP2C11 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin] CTD PMID:19858067 dimethyl sulfoxide multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CYP2C9 mRNA and [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CYP2C9 protein CTD PMID:35366062 diniconazole affects binding ISO CYP2C9 (Homo sapiens) 6480464 diniconazole binds to CYP2C9 protein alternative form CTD PMID:29621561 dioscin increases expression ISO CYP2C9 (Homo sapiens) 6480464 dioscin results in increased expression of CYP2C9 mRNA CTD PMID:29990575 diosmetin decreases activity ISO CYP2C9 (Homo sapiens) 6480464 diosmetin results in decreased activity of CYP2C9 protein CTD PMID:28867436 dioxygen decreases expression ISO CYP2C9 (Homo sapiens) 6480464 Oxygen deficiency results in decreased expression of CYP2C9 mRNA CTD PMID:19695866 dipropyl phthalate decreases activity EXP 6480464 di-n-propylphthalate results in decreased activity of CYP2C11 protein CTD PMID:27432241 disulfiram decreases activity EXP 6480464 Disulfiram results in decreased activity of CYP2C11 protein CTD PMID:9393675 disulfiram decreases expression EXP 6480464 Disulfiram results in decreased expression of CYP2C11 protein CTD PMID:9393675 dodecanoic acid increases hydroxylation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased hydroxylation of lauric acid CTD PMID:11455026 and PMID:9241660 dodecanoic acid decreases hydroxylation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 gene polymorphism results in decreased hydroxylation of lauric acid CTD PMID:11455026 doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of CYP2C11 mRNA and Doxorubicin results in increased expression of CYP2C11 protein CTD PMID:19796650 dronedarone increases metabolic processing ISO CYP2C18 (Homo sapiens) 6480464 CYP2C18 protein results in increased metabolism of Dronedarone CTD PMID:29616291 econazole multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 Econazole binds to and results in decreased activity of CYP2C9 protein and Econazole binds to and results in decreased activity of CYP2C9 protein alternative form CTD PMID:29621561 efavirenz decreases activity ISO CYP2C9 (Homo sapiens) 6480464 efavirenz results in decreased activity of CYP2C9 protein CTD PMID:11225565 ellipticine increases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein mutant form results in increased metabolism of ellipticine CTD PMID:22917556 emodin decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Emodin results in decreased activity of CYP2C9 protein CTD PMID:27633141 and PMID:33438235 enilconazole decreases expression ISO CYP2C9 (Homo sapiens) 6480464 enilconazole results in decreased expression of CYP2C9 mRNA CTD PMID:32201337 epoxiconazole increases expression EXP 6480464 epoxiconazole results in increased expression of CYP2C11 mRNA CTD PMID:29038839 estropipate multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 estropipate promotes the reaction [CYP2C9 protein results in increased metabolism of Coumarins] CTD PMID:14557374 ethanol multiple interactions EXP 6480464 Ethanol promotes the reaction [CYP2C11 protein results in increased oxidation of Toluene] CTD PMID:1994898 ethanol increases expression EXP 6480464 Ethanol results in increased expression of CYP2C11 mRNA CTD PMID:35301062 ethanol decreases expression ISO CYP2C9 (Homo sapiens) 6480464 Ethanol results in decreased expression of CYP2C9 mRNA CTD PMID:31059573 ethanol increases expression ISO CYP2C9 (Homo sapiens) 6480464 Ethanol results in increased expression of CYP2C9 mRNA CTD PMID:35301062 ethanol decreases expression EXP 6480464 Ethanol results in decreased expression of CYP2C11 mRNA CTD PMID:23273579 ethylbenzene decreases expression EXP 6480464 ethylbenzene results in decreased expression of CYP2C11 protein CTD PMID:8135039 ethylene glycol multiple interactions EXP 6480464 [Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of CYP2C9 mRNA and Butyric Acid inhibits the reaction [[Ethylene Glycol co-treated with Calcium Oxalate] results in increased expression of CYP2C9 mRNA] CTD PMID:37414240 ethylparaben decreases activity EXP 6480464 ethyl-p-hydroxybenzoate results in decreased activity of CYP2C11 protein CTD PMID:27432241 eugenol multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [CYP2C9 protein co-treated with Copper] results in increased activity of Eugenol CTD PMID:15576237 farnesol increases activity EXP 6480464 Farnesol results in increased activity of CYP2C11 protein CTD PMID:15840382 felbamate increases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased metabolism of Felbamate CTD PMID:35786679 felodipine decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Felodipine results in decreased activity of CYP2C9 protein CTD PMID:27732883 fenitrothion decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Fenitrothion results in decreased activity of CYP2C9 protein CTD PMID:20183062 and PMID:22634058 fenitrothion multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 Fenitrothion inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Tolbutamide] CTD PMID:22634058 fenofibrate multiple interactions EXP 6480464 [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP2C mRNA CTD PMID:18253720 fenvalerate increases expression ISO CYP2C9 (Homo sapiens) 6480464 fenvalerate results in increased expression of CYP2C9 mRNA CTD PMID:22310298 fimasartan increases hydroxylation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased hydroxylation of fimasartan CTD PMID:29596975 fimasartan increases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased metabolism of fimasartan CTD PMID:29596975 fimasartan increases oxidation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased oxidation of fimasartan CTD PMID:29596975 fipronil multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [fipronil co-treated with DEET] results in increased expression of CYP2C9 mRNA CTD PMID:27091632 fipronil increases expression ISO CYP2C9 (Homo sapiens) 6480464 fipronil results in increased expression of CYP2C9 mRNA CTD PMID:27091632 flavanone multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 flavanone inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Flurbiprofen] CTD PMID:21053930 flavone multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 flavone inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Flurbiprofen] CTD PMID:21053930 flavonoids increases expression EXP 6480464 Flavonoids results in increased expression of CYP2C mRNA CTD PMID:18035473 flavonol multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 3-hydroxyflavone inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Flurbiprofen] CTD PMID:21053930 fluconazole decreases expression EXP 6480464 Fluconazole results in decreased expression of CYP2C mRNA CTD PMID:16643972 fluconazole decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Fluconazole results in decreased activity of CYP2C9 protein CTD PMID:15328084 more ... fluconazole multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [Fluconazole results in decreased activity of CYP2C9 protein] which results in decreased metabolism of Diclofenac more ... CTD PMID:16081671 more ... fluorescein (lactone form) multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [CYP2C9 protein results in increased metabolism of dibenzylfluorescein] which results in increased chemical synthesis of Fluorescein and Sulfaphenazole inhibits the reaction [[CYP2C9 protein results in increased metabolism of dibenzylfluorescein] which results in increased chemical synthesis of Fluorescein] CTD PMID:23850985 fluoxetine multiple interactions EXP 6480464 Fluoxetine inhibits the reaction [CYP2C11 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin] CTD PMID:19858067 fluoxetine affects abundance ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 gene polymorphism affects the abundance of Fluoxetine and CYP2C9 protein affects the abundance of Fluoxetine CTD PMID:14726986 and PMID:15094477 fluoxetine increases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased metabolism of Fluoxetine CTD PMID:14726986 fluphenazine decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Fluphenazine results in decreased activity of CYP2C9 protein CTD PMID:15135088 flurbiprofen multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 3' more ... CTD PMID:15130760 more ... flurbiprofen increases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased metabolism of Flurbiprofen CTD PMID:11901091 more ... flurbiprofen affects hydrolysis ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 gene polymorphism affects the hydrolysis of Flurbiprofen CTD PMID:9698079 flurbiprofen affects hydroxylation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein affects the hydroxylation of Flurbiprofen CTD PMID:15955872 flurbiprofen affects binding ISO CYP2C9 (Homo sapiens) 6480464 Flurbiprofen binds to CYP2C9 protein CTD PMID:21053930 flurbiprofen affects metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 gene polymorphism affects the metabolism of Flurbiprofen CTD PMID:11901091 more ... flurbiprofen increases hydroxylation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein polymorphism results in increased hydroxylation of Flurbiprofen and CYP2C9 protein results in increased hydroxylation of Flurbiprofen CTD PMID:15130760 and PMID:21053930 flurbiprofen increases hydrolysis ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased hydrolysis of Flurbiprofen CTD PMID:9698079 flutamide increases expression EXP 6480464 Flutamide results in increased expression of CYP2C9 mRNA CTD PMID:24793618 flutamide multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Flutamide CTD PMID:23397584 fluvastatin multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 Fluvastatin inhibits the reaction [CYP2C9 protein affects the metabolism of Diclofenac] CTD PMID:16081671 fulvestrant increases expression EXP 6480464 fulvestrant results in increased expression of CYP2C11 mRNA CTD PMID:16837770 fulvestrant increases methylation ISO CYP2C18 (Homo sapiens) 6480464 Fulvestrant results in increased methylation of CYP2C18 gene CTD PMID:31601247 fulvestrant multiple interactions ISO CYP2C18 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of CYP2C18 gene and [bisphenol S co-treated with Fulvestrant] results in increased methylation of CYP2C18 gene CTD PMID:31601247 Furafylline decreases activity EXP 6480464 furafylline results in decreased activity of CYP2C11 protein CTD PMID:15879494 furan decreases expression EXP 6480464 furan results in decreased expression of CYP2C mRNA and furan results in decreased expression of CYP2C11 mRNA CTD PMID:15120968 and PMID:25539665 gadolinium trichloride multiple interactions EXP 6480464 gadolinium chloride inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP2C11 protein] CTD PMID:18079364 galangin multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 galangin inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Flurbiprofen] CTD PMID:21053930 gamma-hexachlorocyclohexane increases expression EXP 6480464 Hexachlorocyclohexane results in increased expression of CYP2C11 mRNA and Hexachlorocyclohexane results in increased expression of CYP2C11 protein CTD PMID:11684361 and PMID:16837770 gemfibrozil decreases expression EXP 6480464 Gemfibrozil results in decreased expression of CYP2C11 protein CTD PMID:9209713 genistein multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 Genistein inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Flurbiprofen] CTD PMID:21053930 genistein decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Genistein results in decreased activity of CYP2C9 protein CTD PMID:29753067 gentamycin multiple interactions EXP 6480464 [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP2C11 mRNA CTD PMID:30545405 glafenine decreases expression EXP 6480464 Glafenine results in decreased expression of CYP2C11 mRNA CTD PMID:24136188 glipizide increases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased metabolism of Glipizide CTD PMID:10208645 glipizide decreases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 gene polymorphism results in decreased metabolism of Glipizide CTD PMID:10208645 glutathione multiple interactions ISO CYP2C18 (Homo sapiens) 6480464 [CYP2C18 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 2'-(glutathion-S-yl)-deschlorodiclofenac and [CYP2C18 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 5-hydroxydiclofenac CTD PMID:24246759 glutathione multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [[CYP2C9 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased hydroxylation of Diclofenac] which results in increased abundance of 4'-hydroxydiclofenac more ... CTD PMID:24246759 more ... glycochenodeoxycholic acid multiple interactions ISO CYP2C18 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of CYP2C18 mRNA more ... CTD PMID:33819548 glycochenodeoxycholic acid multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in decreased expression of CYP2C9 mRNA more ... CTD PMID:33819548 glycocholic acid multiple interactions ISO CYP2C18 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of CYP2C18 mRNA more ... CTD PMID:33819548 glycocholic acid multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in decreased expression of CYP2C9 mRNA more ... CTD PMID:33819548 glycodeoxycholic acid multiple interactions ISO CYP2C18 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of CYP2C18 mRNA more ... CTD PMID:33819548 glycodeoxycholic acid multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in decreased expression of CYP2C9 mRNA more ... CTD PMID:33819548 glyphosate decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Glyphosate results in decreased activity of CYP2C9 protein CTD PMID:20183062 hesperetin decreases activity ISO CYP2C9 (Homo sapiens) 6480464 hesperetin results in decreased activity of CYP2C9 protein CTD PMID:29753067 HET0016 decreases activity ISO CYP2C9 (Homo sapiens) 6480464 HET0016 results in decreased activity of CYP2C9 protein CTD PMID:11375247 hydrogen peroxide increases abundance ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased abundance of Hydrogen Peroxide CTD PMID:25061110 hyperforin increases expression ISO CYP2C9 (Homo sapiens) 6480464 hyperforin results in increased expression of CYP2C9 mRNA CTD PMID:14600250 more ... hyperforin multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 hyperforin results in increased expression of and results in increased activity of CYP2C9 protein and NR1I2 protein affects the reaction [hyperforin results in increased expression of CYP2C9 mRNA] CTD PMID:14600250 and PMID:15100173 ibuprofen multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 Ibuprofen inhibits the reaction [CYP2C9 protein affects the metabolism of Diclofenac] CTD PMID:16081671 ibuprofen affects metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 polymorphism affects the metabolism of Ibuprofen and CYP2C9 protein polymorphism affects the metabolism of Ibuprofen CTD PMID:12152005 and PMID:37406757 ibuprofen decreases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 gene polymorphism results in decreased metabolism of Ibuprofen CTD PMID:15289789 and PMID:18694831 ibuprofen affects binding ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein binds to Ibuprofen CTD PMID:15039296 ibuprofen affects response to substance ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein affects the susceptibility to Ibuprofen CTD PMID:25578229 ibuprofen increases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased metabolism of Ibuprofen CTD PMID:12464242 and PMID:17681167 Icaritin decreases activity ISO CYP2C9 (Homo sapiens) 6480464 icaritin results in decreased activity of CYP2C9 protein CTD PMID:29753067 ifosfamide increases metabolic processing ISO CYP2C18 (Homo sapiens) 6480464 CYP2C18 results in increased metabolism of Ifosfamide CTD PMID:15301741 ifosfamide increases activity ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 results in increased activity of Ifosfamide CTD PMID:9241661 ifosfamide multiple interactions ISO CYP2C18 (Homo sapiens) 6480464 POR promotes the reaction [CYP2C18 results in increased susceptibility to Ifosfamide] CTD PMID:9766669 ifosfamide increases response to substance ISO CYP2C18 (Homo sapiens) 6480464 CYP2C18 results in increased susceptibility to Ifosfamide CTD PMID:15301741 and PMID:9766669 ifosfamide increases response to substance ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased susceptibility to Ifosfamide CTD PMID:20507880 ifosfamide increases activity ISO CYP2C18 (Homo sapiens) 6480464 CYP2C18 results in increased activity of Ifosfamide CTD PMID:9241661 indometacin decreases expression EXP 6480464 Indomethacin results in decreased expression of CYP2C11 mRNA CTD PMID:16771604 inulin multiple interactions ISO Cyp2c52-ps (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of CYP2C52-PS mRNA CTD PMID:36331819 irbesartan increases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased metabolism of Irbesartan CTD PMID:12359989 irbesartan decreases response to substance ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 gene polymorphism results in decreased susceptibility to Irbesartan CTD PMID:12359989 irinotecan decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Irinotecan metabolite results in decreased activity of CYP2C9 protein CTD PMID:11901092 isocarbophos multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased metabolism of and results in decreased sulfation of and affects the activity of isocarbophos CTD PMID:24752505 isoliquiritigenin decreases activity ISO CYP2C9 (Homo sapiens) 6480464 isoliquiritigenin results in decreased activity of CYP2C9 protein CTD PMID:29753067 isoprenaline decreases expression EXP 6480464 Isoproterenol results in decreased expression of CYP2C11 mRNA CTD PMID:18725507 isoproturon decreases activity ISO CYP2C9 (Homo sapiens) 6480464 isoproturon results in decreased activity of CYP2C9 protein CTD PMID:18420780 Isradipine decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Isradipine results in decreased activity of CYP2C9 protein CTD PMID:27732883 ivermectin decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Ivermectin results in decreased activity of CYP2C9 protein CTD PMID:18420780 kaempferol multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 kaempferol inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Flurbiprofen] CTD PMID:21053930 kaempferol decreases activity ISO CYP2C9 (Homo sapiens) 6480464 kaempferol results in decreased activity of CYP2C9 protein CTD PMID:29753067 kahweol multiple interactions EXP 6480464 [cafestol co-treated with kahweol] results in decreased expression of CYP2C11 and [cafestol co-treated with kahweol] results in decreased expression of CYP2C11 protein CTD PMID:11346484 and PMID:9744531 ketoconazole multiple interactions EXP 6480464 Ketoconazole inhibits the reaction [CYP2C11 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin] CTD PMID:19858067 ketoconazole decreases expression ISO CYP2C9 (Homo sapiens) 6480464 Ketoconazole results in decreased expression of CYP2C9 mRNA CTD PMID:16608920 ketoconazole multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 Ketoconazole affects the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid] more ... CTD PMID:16081671 more ... ketoconazole decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Ketoconazole results in decreased activity of CYP2C9 protein CTD PMID:14709627 and PMID:15618748 ketoconazole affects binding ISO CYP2C9 (Homo sapiens) 6480464 Ketoconazole binds to CYP2C9 protein and Ketoconazole binds to CYP2C9 protein alternative form CTD PMID:29621561 ketoconazole decreases activity EXP 6480464 Ketoconazole results in decreased activity of CYP2C11 protein CTD PMID:15879494 kojic acid multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP2C mRNA CTD PMID:18544905 L-methionine multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency] results in decreased expression of CYP2C11 mRNA and [Methionine deficiency co-treated with Choline deficiency] results in decreased expression of CYP2C11 protein CTD PMID:24403518 lamotrigine increases activity EXP 6480464 CYP2C11 protein results in increased activity of lamotrigine CTD PMID:19961160 lamotrigine increases glutathionylation EXP 6480464 CYP2C11 protein results in increased glutathionylation of lamotrigine CTD PMID:19961160 lamotrigine multiple interactions EXP 6480464 Cimetidine inhibits the reaction [CYP2C11 protein results in increased glutathionylation of lamotrigine] CTD PMID:19961160 lansoprazole increases hydroxylation ISO CYP2C18 (Homo sapiens) 6480464 CYP2C18 protein results in increased hydroxylation of Lansoprazole CTD PMID:7870052 lansoprazole multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 Lansoprazole inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Diclofenac] CTD PMID:15258107 lansoprazole increases hydroxylation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased hydroxylation of Lansoprazole CTD PMID:12975331 and PMID:8627562 lead nitrate increases expression EXP 6480464 lead nitrate results in increased expression of CYP2C11 mRNA CTD PMID:23391631 lead(0) decreases expression ISO CYP2C9 (Homo sapiens) 6480464 Lead results in decreased expression of CYP2C9 mRNA CTD PMID:19921347 leflunomide increases expression ISO CYP2C9 (Homo sapiens) 6480464 Leflunomide results in increased expression of CYP2C9 mRNA CTD PMID:30364229 Licochalcone A decreases activity ISO CYP2C9 (Homo sapiens) 6480464 licochalcone A results in decreased activity of CYP2C9 protein CTD PMID:26100226 linoleic acid decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Linoleic Acid results in decreased activity of CYP2C9 protein CTD PMID:16978661 linoleic acid multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased metabolism of [Linoleic Acid co-treated with NADP] CTD PMID:16978661 lipoic acid multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 Thioctic Acid inhibits the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid] CTD PMID:24120545 liquiritigenin decreases activity ISO CYP2C9 (Homo sapiens) 6480464 liquiritigenin results in decreased activity of CYP2C9 protein CTD PMID:29753067 lithocholic acid increases metabolic processing EXP 6480464 CYP2C11 protein results in increased metabolism of Lithocholic Acid CTD PMID:18039809 lithocholic acid decreases activity EXP 6480464 Lithocholic Acid results in decreased activity of CYP2C11 protein CTD PMID:8889968 lithocholic acid multiple interactions EXP 6480464 [CYP2C11 protein results in increased metabolism of Lithocholic Acid] which results in increased chemical synthesis of 3-oxocholan-24-oic acid CTD PMID:18039809 losartan increases hydroxylation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased hydroxylation of Losartan CTD PMID:25994031 losartan increases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased metabolism of Losartan CTD PMID:19082874 more ... losartan multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 gene mutant form inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Losartan] and Resveratrol inhibits the reaction [CYP2C9 protein results in increased metabolism of Losartan] CTD PMID:20716633 and PMID:25994031 losartan affects metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein affects the metabolism of Losartan CTD PMID:20405111 and PMID:21321060 luteolin decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Luteolin results in decreased activity of CYP2C9 protein CTD PMID:29753067 Luteolin 7-methyl ether decreases activity EXP 6480464 hydroxygenkwanin results in decreased activity of CYP2C11 protein CTD PMID:34843882 Luteolin 7-methyl ether decreases activity ISO CYP2C9 (Homo sapiens) 6480464 hydroxygenkwanin results in decreased activity of CYP2C9 protein CTD PMID:34843882 m-xylene decreases expression EXP 6480464 3-xylene results in decreased expression of CYP2C mRNA CTD PMID:12815608 malathion decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Malathion results in decreased activity of CYP2C9 protein CTD PMID:20183062 and PMID:22634058 malathion multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 Malathion inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Tolbutamide] CTD PMID:22634058 mangiferin decreases activity ISO CYP2C9 (Homo sapiens) 6480464 mangiferin results in decreased activity of CYP2C9 protein CTD PMID:22815239 manidipine decreases activity ISO CYP2C9 (Homo sapiens) 6480464 manidipine results in decreased activity of CYP2C9 protein CTD PMID:10805063 Marrubiin increases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased metabolism of marrubiin CTD PMID:34431289 mefenamic acid increases glutathionylation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased glutathionylation of Mefenamic Acid analog CTD PMID:25372302 mefenamic acid increases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased metabolism of Mefenamic Acid CTD PMID:12464242 mefenamic acid increases hydroxylation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased hydroxylation of Mefenamic Acid CTD PMID:25372302 mefenamic acid increases oxidation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased oxidation of Mefenamic Acid CTD PMID:33259822 MeIQx increases expression EXP 6480464 2-amino-3 more ... CTD PMID:14965361 Melarsoprol decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Melarsoprol results in decreased activity of CYP2C9 protein CTD PMID:11124226 methapyrilene decreases activity EXP 6480464 Methapyrilene results in decreased activity of CYP2C11 protein CTD PMID:9928682 methotrexate decreases expression ISO CYP2C9 (Homo sapiens) 6480464 Methotrexate results in decreased expression of CYP2C9 mRNA CTD PMID:24449571 methoxsalen decreases activity EXP 6480464 Methoxsalen results in decreased activity of CYP2C11 protein CTD PMID:12814958 and PMID:15879494 methoxsalen decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Methoxsalen results in decreased activity of CYP2C9 protein CTD PMID:18420780 methoxychlor increases metabolic processing EXP 6480464 CYP2C11 protein results in increased metabolism of Methoxychlor CTD PMID:14613717 methoxychlor decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Methoxychlor results in decreased activity of CYP2C9 protein CTD PMID:18420780 methoxychlor multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [CYP2C19 protein co-treated with CYP2C9 protein] results in decreased methylation of Methoxychlor CTD PMID:15486075 methoxychlor decreases methylation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in decreased methylation of Methoxychlor CTD PMID:12167570 and PMID:9733665 methoxychlor decreases methylation ISO CYP2C18 (Homo sapiens) 6480464 CYP2C18 protein results in decreased methylation of Methoxychlor CTD PMID:9733665 methoxychlor increases expression EXP 6480464 Methoxychlor results in increased expression of CYP2C11 mRNA CTD PMID:14613717 methoxychlor decreases expression EXP 6480464 Methoxychlor results in decreased expression of CYP2C11 protein CTD PMID:12919727 methoxychlor decreases activity EXP 6480464 Methoxychlor results in decreased activity of CYP2C11 protein CTD PMID:8114062 methylarsonic acid increases expression EXP 6480464 monomethylarsonic acid results in increased expression of CYP2C11 mRNA CTD PMID:17481689 Methysticin multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 methysticin inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Diclofenac] more ... CTD PMID:35583123 Methysticin decreases activity EXP 6480464 methysticin results in decreased activity of CYP2C9 protein CTD PMID:16033948 Methysticin decreases activity ISO CYP2C9 (Homo sapiens) 6480464 methysticin results in decreased activity of CYP2C9 protein CTD PMID:35583123 metronidazole multiple interactions EXP 6480464 [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP2C11 mRNA CTD PMID:30545405 miconazole multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 Miconazole inhibits the reaction [[CYP2C9 protein results in increased hydroxylation of Phenytoin] which results in increased abundance of hydroxyphenytoin] more ... CTD PMID:16081671 and PMID:33961833 miconazole decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Miconazole results in decreased activity of CYP2C9 protein CTD PMID:15328084 miconazole affects binding ISO CYP2C9 (Homo sapiens) 6480464 Miconazole binds to CYP2C9 protein and Miconazole binds to CYP2C9 protein alternative form CTD PMID:29621561 mitomycin C decreases activity EXP 6480464 Mitomycin results in decreased activity of CYP2C11 protein CTD PMID:15696929 mono(2-ethyl-5-hydroxyhexyl) phthalate multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [CYP2C9 protein polymorphism results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of mono(2-ethyl-5-hydroxyhexyl) phthalate and [CYP2C9 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of mono(2-ethyl-5-hydroxyhexyl) phthalate CTD PMID:22186153 and PMID:23545481 mono(2-ethyl-5-oxohexyl) phthalate multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [CYP2C9 protein polymorphism results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of mono(2-ethyl-5-oxohexyl)phthalate and [CYP2C9 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of mono(2-ethyl-5-oxohexyl)phthalate CTD PMID:22186153 and PMID:23545481 mono(2-ethylhexyl) phthalate decreases activity EXP 6480464 mono-(2-ethylhexyl)phthalate results in decreased activity of CYP2C11 protein CTD PMID:27432241 mono(2-ethylhexyl) phthalate multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [CYP2C9 protein polymorphism results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of 2-ethyl-5-carboxypentyl phthalate more ... CTD PMID:22186153 and PMID:23545481 mono(2-ethylhexyl) phthalate increases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein polymorphism results in increased metabolism of mono-(2-ethylhexyl)phthalate and CYP2C9 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate CTD PMID:22186153 and PMID:23545481 mono(5-carboxy-2-ethylpentyl) phthalate multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [CYP2C9 protein polymorphism results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of 2-ethyl-5-carboxypentyl phthalate CTD PMID:23545481 monosodium L-glutamate decreases expression EXP 6480464 Sodium Glutamate results in decreased expression of CYP2C11 mRNA CTD PMID:8496838 monosodium L-glutamate increases expression EXP 6480464 Sodium Glutamate results in increased expression of CYP2C11 mRNA more ... CTD PMID:11089541 more ... monosodium L-glutamate multiple interactions EXP 6480464 [Sodium Glutamate co-treated with GH1 protein] results in decreased splicing of CYP2C11 mRNA more ... CTD PMID:11089541 more ... monosodium L-glutamate decreases activity EXP 6480464 Sodium Glutamate results in decreased activity of CYP2C11 protein CTD PMID:7476908 and PMID:8496838 myricetin decreases activity ISO CYP2C9 (Homo sapiens) 6480464 myricetin results in decreased activity of CYP2C9 protein CTD PMID:29753067 N,N-diethyl-m-toluamide increases expression ISO CYP2C9 (Homo sapiens) 6480464 DEET results in increased expression of CYP2C9 mRNA CTD PMID:27091632 N,N-diethyl-m-toluamide multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [fipronil co-treated with DEET] results in increased expression of CYP2C9 mRNA CTD PMID:27091632 N-acetyl-L-cysteine multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 Acetylcysteine affects the reaction [CYP2C9 protein results in increased hydroxylation of bromfenac] CTD PMID:31815452 N-desmethylclozapine increases chemical synthesis ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased chemical synthesis of norclozapine CTD PMID:18809730 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased expression of CYP2C11 mRNA more ... CTD PMID:16246485 more ... N-nitrosodiethylamine decreases expression EXP 6480464 Diethylnitrosamine results in decreased expression of CYP2C mRNA more ... CTD PMID:14965361 more ... N-nitrosodimethylamine decreases expression EXP 6480464 Dimethylnitrosamine results in decreased expression of CYP2C mRNA and Dimethylnitrosamine results in decreased expression of CYP2C11 mRNA CTD PMID:17072980 and PMID:25380136 NADP zwitterion multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid more ... CTD PMID:16978661 more ... NADP(+) multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid more ... CTD PMID:16978661 more ... naphthalene increases expression ISO CYP2C9 (Homo sapiens) 6480464 naphthalene results in increased expression of CYP2C9 mRNA CTD PMID:20500019 naproxen increases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased metabolism of Naproxen CTD PMID:11901091 more ... naproxen multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 Amiodarone promotes the reaction [CYP2C9 protein affects the metabolism of Naproxen] more ... CTD PMID:15130760 and PMID:16081671 naproxen affects metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 gene polymorphism affects the metabolism of Naproxen and CYP2C9 protein affects the metabolism of Naproxen CTD PMID:11901091 and PMID:16081671 naproxen decreases methylation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein polymorphism results in decreased methylation of Naproxen and CYP2C9 protein results in decreased methylation of Naproxen CTD PMID:15130760 naringin multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 naringin inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Flurbiprofen] CTD PMID:21053930 nateglinide affects metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein affects the metabolism of Nateglinide CTD PMID:18159128 nefazodone multiple interactions ISO CYP2C18 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of CYP2C18 mRNA CTD PMID:33819548 nefazodone multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of CYP2C9 mRNA CTD PMID:33819548 neomycin multiple interactions EXP 6480464 [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP2C11 mRNA CTD PMID:30545405 nevirapine affects binding EXP 6480464 Nevirapine binds to CYP2C11 protein CTD PMID:22793666 nicardipine decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Nicardipine results in decreased activity of CYP2C9 protein CTD PMID:10805063 and PMID:15863898 niclosamide multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 Niclosamide promotes the reaction [CYP2C9 protein results in increased metabolism of Coumarins] CTD PMID:14557374 niclosamide increases activity ISO CYP2C9 (Homo sapiens) 6480464 Niclosamide results in increased activity of CYP2C9 protein CTD PMID:11124226 nifedipine multiple interactions EXP 6480464 Nifedipine promotes the reaction [Cyclosporine results in increased expression of CYP2C11 protein] CTD PMID:28899749 nimesulide increases glutathionylation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased glutathionylation of nimesulide CTD PMID:26524229 Nonylphenol decreases activity EXP 6480464 nonylphenol results in decreased activity of CYP2C11 protein CTD PMID:11731036 Nonylphenol decreases expression EXP 6480464 nonylphenol results in decreased expression of CYP2C11 protein CTD PMID:11731036 Notopterol multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [CYP2C9 protein results in increased metabolism of notopterol] promotes the reaction [Glutathione binds to notopterol] CTD PMID:32198085 Notopterol increases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased metabolism of notopterol CTD PMID:32198085 O-methyleugenol decreases expression ISO CYP2C9 (Homo sapiens) 6480464 methyleugenol results in decreased expression of CYP2C9 mRNA CTD PMID:32234424 obeticholic acid decreases expression ISO CYP2C9 (Homo sapiens) 6480464 obeticholic acid results in decreased expression of CYP2C9 mRNA CTD PMID:27939613 ochratoxin A decreases expression EXP 6480464 ochratoxin A results in decreased expression of CYP2C mRNA and ochratoxin A results in decreased expression of CYP2C11 mRNA CTD PMID:18417182 and PMID:30449730 ochratoxin A increases response to substance ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased susceptibility to ochratoxin A CTD PMID:21781659 and PMID:8542584 ochratoxin A increases expression ISO CYP2C9 (Homo sapiens) 6480464 ochratoxin A results in increased expression of CYP2C9 mRNA CTD PMID:21834667 ochratoxin A affects methylation EXP 6480464 ochratoxin A affects the methylation of CYP2C11 promoter CTD PMID:30449730 ochratoxin A increases expression EXP 6480464 ochratoxin A results in increased expression of CYP2C mRNA CTD PMID:16251485 okanin decreases activity ISO CYP2C9 (Homo sapiens) 6480464 okanin results in decreased activity of CYP2C9 protein CTD PMID:29753067 oltipraz affects metabolic processing EXP 6480464 CYP2C11 protein affects the metabolism of oltipraz CTD PMID:15831204 and PMID:15920769 omeprazole multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 Omeprazole inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Diclofenac] CTD PMID:15258107 oxalic acid increases expression ISO CYP2C9 (Homo sapiens) 6480464 Oxalic Acid results in increased expression of CYP2C9 mRNA CTD PMID:37414240 oxalic acid multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [Butyric Acid co-treated with Sulfaphenazole] inhibits the reaction [Oxalic Acid results in increased expression of CYP2C9 mRNA] more ... CTD PMID:37414240 oxycodone decreases expression EXP 6480464 Oxycodone results in decreased expression of CYP2C11 mRNA and Oxycodone results in decreased expression of CYP2C9 mRNA CTD PMID:23439660 ozone multiple interactions EXP 6480464 [Ozone co-treated with Chlorine] affects the expression of CYP2C mRNA CTD PMID:18636392 p-menthan-3-ol increases expression ISO CYP2C9 (Homo sapiens) 6480464 Menthol results in increased expression of CYP2C9 mRNA CTD PMID:24594507 p-tert-Amylphenol increases response to substance ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 gene SNP results in increased susceptibility to 4-tert-octylphenol CTD PMID:23555028 paclitaxel increases activity ISO CYP2C9 (Homo sapiens) 6480464 Paclitaxel results in increased activity of CYP2C9 protein CTD PMID:19202563 paclitaxel decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Paclitaxel results in decreased activity of CYP2C9 protein CTD PMID:19909766 pantoprazole multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 Pantoprazole inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Diclofenac] CTD PMID:15258107 paracetamol multiple interactions EXP 6480464 [Acetaminophen co-treated with Uranium analog] results in decreased expression of CYP2C11 mRNA CTD PMID:17126469 paracetamol increases expression ISO CYP2C9 (Homo sapiens) 6480464 Acetaminophen results in increased expression of CYP2C9 mRNA CTD PMID:22230336 paracetamol decreases expression ISO CYP2C9 (Homo sapiens) 6480464 Acetaminophen results in decreased expression of CYP2C9 mRNA CTD PMID:29067470 paracetamol multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of CYP2C9 mRNA CTD PMID:33819548 paracetamol multiple interactions ISO CYP2C18 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of CYP2C18 mRNA CTD PMID:33819548 paracetamol decreases expression ISO CYP2C18 (Homo sapiens) 6480464 Acetaminophen results in decreased expression of CYP2C18 mRNA CTD PMID:21420995 and PMID:29067470 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of CYP2C11 mRNA CTD PMID:17126469 and PMID:21807079 paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of CYP2C mRNA CTD PMID:17366322 Paraoxon-methyl increases chemical synthesis EXP 6480464 CYP2C11 protein results in increased chemical synthesis of methylparaoxon CTD PMID:22271348 parathion increases expression ISO CYP2C9 (Homo sapiens) 6480464 Parathion results in increased expression of CYP2C9 mRNA CTD PMID:26196221 parathion affects metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein affects the metabolism of Parathion CTD PMID:17079358 parathion-methyl increases metabolic processing EXP 6480464 CYP2C11 protein results in increased metabolism of Methyl Parathion CTD PMID:22271348 pedalitin decreases activity ISO CYP2C9 (Homo sapiens) 6480464 pedalitin results in decreased activity of CYP2C9 protein CTD PMID:29753067 penconazole affects binding ISO CYP2C9 (Homo sapiens) 6480464 penconazole binds to CYP2C9 protein alternative form CTD PMID:29621561 pentamidine decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Pentamidine results in decreased activity of CYP2C9 protein CTD PMID:11124226 perazine affects metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 gene polymorphism affects the metabolism of Perazine CTD PMID:11026737 perazine decreases methylation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in decreased methylation of Perazine CTD PMID:11026737 perfluorooctane-1-sulfonic acid multiple interactions ISO Cyp2c52-ps (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of CYP2C52-PS mRNA and [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of CYP2C52-PS mRNA CTD PMID:36331819 perfluorooctane-1-sulfonic acid multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 perfluorooctane sulfonic acid inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Diclofenac] CTD PMID:21964418 perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of CYP2C11 protein CTD PMID:34958885 phenacetin affects metabolic processing EXP 6480464 CYP2C11 protein affects the metabolism of Phenacetin CTD PMID:15879494 phencyclidine affects metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein affects the metabolism of Phencyclidine CTD PMID:16782764 phenobarbital multiple interactions EXP 6480464 [Dehydroepiandrosterone Sulfate co-treated with Phenobarbital] results in increased expression of CYP2C11 protein more ... CTD PMID:1994898 more ... phenobarbital increases activity ISO CYP2C9 (Homo sapiens) 6480464 Phenobarbital results in increased activity of CYP2C9 mRNA and Phenobarbital results in increased activity of CYP2C9 protein CTD PMID:19202563 and PMID:19328226 phenobarbital affects metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 gene polymorphism affects the metabolism of Phenobarbital CTD PMID:17304159 phenobarbital multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [Progesterone co-treated with Estradiol] inhibits the reaction [Phenobarbital results in increased expression of CYP2C9 mRNA] more ... CTD PMID:15802389 more ... phenobarbital increases expression ISO CYP2C9 (Homo sapiens) 6480464 Phenobarbital results in increased expression of CYP2C9 mRNA and Phenobarbital results in increased expression of CYP2C9 protein CTD PMID:15629111 more ... phenobarbital decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Phenobarbital results in decreased activity of CYP2C9 protein CTD PMID:19909766 phenobarbital increases expression ISO CYP2C18 (Homo sapiens) 6480464 Phenobarbital results in increased expression of CYP2C37 mRNA more ... CTD PMID:28541575 phenobarbital decreases expression EXP 6480464 Phenobarbital results in decreased expression of CYP2C11 protein CTD PMID:30842367 phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of CYP2C mRNA more ... CTD PMID:19162173 more ... phenobarbital increases activity EXP 6480464 Phenobarbital results in increased activity of CYP2C11 protein CTD PMID:16781091 phenprocoumon affects response to substance ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 gene polymorphism affects the susceptibility to Phenprocoumon CTD PMID:18698879 phenprocoumon increases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased metabolism of Phenprocoumon CTD PMID:19082874 phenthoate multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 phenthoate inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Tolbutamide] CTD PMID:22634058 phenthoate decreases activity ISO CYP2C9 (Homo sapiens) 6480464 phenthoate results in decreased activity of CYP2C9 protein CTD PMID:22634058 phenytoin affects metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein affects the metabolism of Phenytoin and CYP2C9 protein alternative form affects the metabolism of Phenytoin CTD PMID:15855726 more ... phenytoin decreases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 5' UTR polymorphism results in decreased metabolism of Phenytoin and CYP2C9 gene polymorphism results in decreased metabolism of Phenytoin CTD PMID:10208645 more ... phenytoin increases response to substance ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 gene polymorphism results in increased susceptibility to Phenytoin CTD PMID:11740344 phenytoin increases hydroxylation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased hydroxylation of Phenytoin CTD PMID:16873909 more ... phenytoin decreases hydroxylation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 gene polymorphism results in decreased hydroxylation of Phenytoin CTD PMID:16873909 and PMID:9860067 phenytoin increases metabolic processing EXP 6480464 CYP2C9 protein results in increased metabolism of Phenytoin CTD PMID:15569425 phenytoin increases activity ISO CYP2C9 (Homo sapiens) 6480464 Phenytoin results in increased activity of CYP2C9 protein CTD PMID:19202563 phenytoin increases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased metabolism of Phenytoin CTD PMID:10208645 more ... phenytoin increases expression ISO CYP2C9 (Homo sapiens) 6480464 Phenytoin results in increased expression of CYP2C9 mRNA CTD PMID:14600250 phenytoin multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [Clozapine results in decreased activity of CYP2C9 protein] which results in increased susceptibility to Phenytoin more ... CTD PMID:14600250 more ... phthalic acid multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [CYP2C9 protein polymorphism results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of phthalic acid CTD PMID:23545481 picoxystrobin decreases activity ISO CYP2C9 (Homo sapiens) 6480464 picoxystrobin results in decreased activity of CYP2C9 protein CTD PMID:23611293 pirinixic acid decreases expression ISO Cyp2c52-ps (Mus musculus) 6480464 pirinixic acid results in decreased expression of CYP2C11 protein CTD PMID:17405874 pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of CYP2C mRNA and pirinixic acid results in decreased expression of CYP2C11 protein CTD PMID:19162173 and PMID:9209713 piroxicam affects metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 gene polymorphism affects the metabolism of Piroxicam CTD PMID:11901091 piroxicam increases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased metabolism of Piroxicam CTD PMID:11901091 more ... piroxicam multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 Piroxicam inhibits the reaction [CYP2C9 protein affects the metabolism of Diclofenac] CTD PMID:16081671 poly(I:C) decreases expression EXP 6480464 Poly I-C results in decreased expression of CYP2C11 mRNA CTD PMID:23939143 poly(styrene) multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 styrofoam analog promotes the reaction [Cimetidine results in decreased activity of CYP2C9 protein] CTD PMID:19909766 poly(styrene) decreases activity ISO CYP2C9 (Homo sapiens) 6480464 styrofoam analog results in decreased activity of CYP2C9 protein CTD PMID:19909766 polymyxin B2 multiple interactions EXP 6480464 Polymyxin B inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP2C11 protein] CTD PMID:18079364 potassium hexacyanoferrate(3-) multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 potassium ferricyanide affects the reaction [methysticin results in decreased activity of CYP2C9 protein] CTD PMID:35583123 pregnenolone 16alpha-carbonitrile increases expression EXP 6480464 Pregnenolone Carbonitrile results in increased expression of CYP2C mRNA CTD PMID:19162173 prochloraz increases expression EXP 6480464 prochloraz results in increased expression of CYP2C11 protein CTD PMID:33150952 profenofos decreases expression EXP 6480464 profenofos results in decreased expression of CYP2C11 mRNA and profenofos results in decreased expression of CYP2C11 protein CTD PMID:18828448 profenofos decreases activity ISO CYP2C9 (Homo sapiens) 6480464 profenofos results in decreased activity of CYP2C9 protein CTD PMID:22634058 profenofos multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 profenofos inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Tolbutamide] CTD PMID:22634058 progesterone decreases expression ISO CYP2C18 (Homo sapiens) 6480464 Progesterone results in decreased expression of CYP2C18 mRNA CTD PMID:18070364 progesterone multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [Progesterone co-treated with Estradiol] inhibits the reaction [6-(4-chlorophenyl)imidazo(2 more ... CTD PMID:21768169 propanal increases expression ISO CYP2C18 (Homo sapiens) 6480464 propionaldehyde results in increased expression of CYP2C18 mRNA CTD PMID:26079696 propanal decreases expression ISO CYP2C9 (Homo sapiens) 6480464 propionaldehyde results in decreased expression of CYP2C9 mRNA CTD PMID:26079696 propiconazole decreases expression EXP 6480464 propiconazole results in decreased expression of CYP2C11 protein CTD PMID:7986207 propranolol increases oxidation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased oxidation of Propranolol CTD PMID:19853591 propylbenzene decreases expression EXP 6480464 n-propylbenzene results in decreased expression of CYP2C11 protein CTD PMID:8135039 propylparaben decreases activity EXP 6480464 propylparaben results in decreased activity of CYP2C11 protein CTD PMID:27432241 pyrene affects expression EXP 6480464 pyrene affects the expression of CYP2C11 mRNA CTD PMID:30240548 pyrimethamine decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Pyrimethamine results in decreased activity of CYP2C9 protein CTD PMID:11124226 pyrimidin-2-amine affects binding EXP 6480464 2-aminopyrimidine analog binds to CYP2C11 protein CTD PMID:19317514 quercetin multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 Quercetin inhibits the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid] and Quercetin inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Flurbiprofen] CTD PMID:21053930 and PMID:24120545 quercetin decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Quercetin results in decreased activity of CYP2C9 protein CTD PMID:18420780 and PMID:29753067 quercetin increases expression ISO CYP2C9 (Homo sapiens) 6480464 Quercetin results in increased expression of CYP2C9 mRNA CTD PMID:21632981 quinine decreases activity EXP 6480464 Quinine results in decreased activity of CYP2C11 protein CTD PMID:12814958 and PMID:15879494 quinine decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Quinine results in decreased activity of CYP2C9 protein CTD PMID:11124226 quinine multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 Quinine inhibits the reaction [CYP2C9 protein affects the metabolism of Diclofenac] CTD PMID:16081671 resveratrol multiple interactions ISO CYP2C18 (Homo sapiens) 6480464 [Plant Extracts co-treated with Resveratrol] results in decreased expression of CYP2C18 mRNA CTD PMID:23557933 resveratrol decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Resveratrol results in decreased activity of CYP2C9 protein CTD PMID:18420780 and PMID:30394306 resveratrol multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [Plant Extracts co-treated with Resveratrol] results in decreased expression of CYP2C9 mRNA and Resveratrol inhibits the reaction [CYP2C9 protein results in increased metabolism of Losartan] CTD PMID:20716633 and PMID:23557933 Rhein decreases activity ISO CYP2C9 (Homo sapiens) 6480464 rhein results in decreased activity of CYP2C9 protein CTD PMID:27633141 and PMID:33438235 riddelliine decreases expression EXP 6480464 riddelliine results in decreased expression of CYP2C mRNA CTD PMID:18047722 and PMID:18047727 rifampicin decreases expression ISO CYP2C18 (Homo sapiens) 6480464 Rifampin results in decreased expression of CYP2C18 mRNA and Rifampin results in decreased expression of CYP2C18 protein CTD PMID:22258563 and PMID:31629065 rifampicin multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 Ketoconazole inhibits the reaction [Rifampin results in increased expression of CYP2C9 mRNA] more ... CTD PMID:14600250 more ... rifampicin affects response to substance ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 alternative form affects the susceptibility to Rifampin CTD PMID:36789833 rifampicin increases expression ISO CYP2C9 (Homo sapiens) 6480464 Rifampin results in increased expression of CYP2C9 mRNA and Rifampin results in increased expression of CYP2C9 protein CTD PMID:14600250 more ... rifampicin increases activity ISO CYP2C9 (Homo sapiens) 6480464 Rifampin results in increased activity of CYP2C9 protein CTD PMID:14722322 more ... ritonavir increases activity ISO CYP2C9 (Homo sapiens) 6480464 Ritonavir results in increased activity of CYP2C9 protein CTD PMID:19202563 ritonavir increases expression ISO CYP2C9 (Homo sapiens) 6480464 Ritonavir results in increased expression of CYP2C9 mRNA CTD PMID:11918509 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of CYP2C11 mRNA CTD PMID:28374803 rubiadin decreases activity ISO CYP2C9 (Homo sapiens) 6480464 rubiadin results in decreased activity of CYP2C9 protein CTD PMID:33438235 senecionine decreases expression ISO CYP2C18 (Homo sapiens) 6480464 senecionine results in decreased expression of CYP2C18 mRNA CTD PMID:26100227 sertraline multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in decreased methylation of and results in increased metabolism of Sertraline and Sertraline inhibits the reaction [CYP2C9 protein affects the metabolism of Diclofenac] CTD PMID:15547048 and PMID:16081671 sevoflurane affects expression EXP 6480464 sevoflurane affects the expression of CYP2C mRNA and sevoflurane affects the expression of CYP2C11 mRNA CTD PMID:15967596 Shikonin decreases activity EXP 6480464 shikonin results in decreased activity of CYP2C11 protein CTD PMID:28941798 Shikonin decreases activity ISO CYP2C9 (Homo sapiens) 6480464 shikonin results in decreased activity of CYP2C9 protein CTD PMID:28941798 silibinin decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Silybin results in decreased activity of CYP2C9 protein CTD PMID:15155549 silicon dioxide increases expression ISO CYP2C18 (Homo sapiens) 6480464 Silicon Dioxide results in increased expression of CYP2C18 mRNA CTD PMID:25351596 silicon dioxide decreases expression ISO CYP2C9 (Homo sapiens) 6480464 Silicon Dioxide analog results in decreased expression of CYP2C9 mRNA CTD PMID:25895662 simazine decreases activity EXP 6480464 Simazine results in decreased activity of CYP2C11 protein CTD PMID:9711812 simvastatin multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 Simvastatin affects the reaction [CYP2C9 polymorphism affects the susceptibility to Warfarin] CTD PMID:22594507 sirolimus increases expression ISO CYP2C9 (Homo sapiens) 6480464 Sirolimus results in increased expression of CYP2C9 mRNA CTD PMID:25929522 sirolimus decreases expression ISO CYP2C9 (Homo sapiens) 6480464 Sirolimus results in decreased expression of CYP2C9 protein CTD PMID:25929522 sodium arsenate multiple interactions ISO CYP2C18 (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of CYP2C18 mRNA CTD PMID:32525701 sodium arsenite decreases expression ISO CYP2C18 (Homo sapiens) 6480464 sodium arsenite results in decreased expression of CYP2C18 mRNA CTD PMID:29301061 sodium arsenite decreases expression ISO CYP2C9 (Homo sapiens) 6480464 sodium arsenite results in decreased expression of CYP2C9 mRNA CTD PMID:29301061 sophoranone decreases activity ISO CYP2C9 (Homo sapiens) 6480464 sophoranone results in decreased activity of CYP2C9 protein CTD PMID:29753067 sorafenib decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Sorafenib metabolite results in decreased activity of CYP2C9 protein and Sorafenib results in decreased activity of CYP2C9 protein CTD PMID:33556367 sporidesmin A increases expression ISO CYP2C18 (Homo sapiens) 6480464 sporidesmin results in increased expression of CYP2C18 mRNA and sporidesmin results in increased expression of CYP2C18 protein CTD PMID:28193462 sporidesmin A increases expression ISO CYP2C9 (Homo sapiens) 6480464 sporidesmin results in increased expression of CYP2C9 mRNA CTD PMID:28193462 sporidesmin A multiple interactions ISO CYP2C18 (Homo sapiens) 6480464 MIR21 mRNA affects the reaction [sporidesmin results in increased expression of CYP2C18 mRNA] and MIR31 mRNA affects the reaction [sporidesmin results in increased expression of CYP2C18 mRNA] CTD PMID:28193462 steviol multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 steviol binds to and results in decreased activity of CYP2C9 protein CTD PMID:28887089 stevioside decreases expression ISO CYP2C9 (Homo sapiens) 6480464 stevioside results in decreased expression of CYP2C9 mRNA CTD PMID:28887089 streptozocin multiple interactions EXP 6480464 [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP2C11 mRNA and [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP2C11 protein CTD PMID:24815820 styrene decreases expression EXP 6480464 Styrene results in decreased expression of CYP2C11 mRNA CTD PMID:16418063 styrene oxide multiple interactions EXP 6480464 CYP2C11 protein promotes the reaction [EPHX1 protein affects the hydrolysis of styrene oxide] CTD PMID:12051674 Sudan I decreases activity EXP 6480464 1-phenylazo-2-naphthol results in decreased activity of CYP2C11 protein CTD PMID:26845733 Sudan I increases oxidation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased oxidation of 1-phenylazo-2-naphthol CTD PMID:17159775 Sudan I multiple interactions EXP 6480464 [aristolochic acid I co-treated with 1-phenylazo-2-naphthol] results in decreased activity of CYP2C11 protein CTD PMID:26845733 Sudan III multiple interactions EXP 6480464 [sudan III binds to AHR protein] inhibits the reaction [[Clofibric Acid binds to PPARA protein] which results in decreased activity of CYP2C11 protein] more ... CTD PMID:15788368 Sudan III decreases expression EXP 6480464 sudan III results in decreased expression of CYP2C11 mRNA CTD PMID:15788368 sulfadiazine increases hydroxylation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased hydroxylation of Sulfadiazine CTD PMID:15843491 sulfaphenazole decreases expression EXP 6480464 Sulfaphenazole results in decreased expression of CYP2C11 CTD PMID:15890479 sulfaphenazole multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [Butyric Acid co-treated with Sulfaphenazole] inhibits the reaction [Oxalic Acid results in increased expression of CYP2C9 mRNA] more ... CTD PMID:10991840 more ... sulfaphenazole decreases expression ISO CYP2C9 (Homo sapiens) 6480464 Sulfaphenazole results in decreased expression of CYP2C9 mRNA CTD PMID:24519941 sulfaphenazole decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Sulfaphenazole results in decreased activity of CYP2C9 protein CTD PMID:12464242 more ... sulfaphenazole increases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased metabolism of Sulfaphenazole CTD PMID:17702393 and PMID:19309152 sulfinpyrazone multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 Sulfinpyrazone inhibits the reaction [CYP2C9 protein affects the metabolism of Diclofenac] CTD PMID:16081671 sunitinib decreases expression EXP 6480464 sunitinib results in decreased expression of CYP2C11 mRNA CTD PMID:26797788 Sunset Yellow FCF multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in decreased expression of CYP2C9 mRNA CTD PMID:33819548 tamoxifen multiple interactions EXP 6480464 Tamoxifen promotes the reaction [testosterone enanthate results in increased expression of CYP2C11 protein] CTD PMID:8573203 tamoxifen multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Tamoxifen CTD PMID:23397584 tamoxifen increases activity ISO CYP2C9 (Homo sapiens) 6480464 Tamoxifen metabolite results in increased activity of CYP2C9 protein CTD PMID:29285606 tartrazine multiple interactions ISO CYP2C18 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of CYP2C18 mRNA CTD PMID:33819548 tartrazine multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of CYP2C9 mRNA CTD PMID:33819548 taurocholic acid decreases activity EXP 6480464 Taurocholic Acid results in decreased activity of CYP2C11 protein CTD PMID:8889968 tebuconazole affects binding ISO CYP2C9 (Homo sapiens) 6480464 tebuconazole binds to CYP2C9 protein and tebuconazole binds to CYP2C9 protein alternative form CTD PMID:29621561 tenofovir disoproxil fumarate decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Tenofovir results in decreased activity of CYP2C9 protein CTD PMID:17162464 teriflunomide increases expression ISO CYP2C9 (Homo sapiens) 6480464 teriflunomide results in increased expression of CYP2C9 mRNA CTD PMID:30364229 testosterone affects metabolic processing EXP 6480464 CYP2C11 protein affects the metabolism of Testosterone CTD PMID:15879494 testosterone increases expression EXP 6480464 Testosterone results in increased expression of CYP2C11 mRNA CTD PMID:16837770 testosterone enanthate increases expression EXP 6480464 testosterone enanthate results in increased expression of CYP2C11 mRNA and testosterone enanthate results in increased expression of CYP2C11 protein CTD PMID:8573203 and PMID:8819526 testosterone enanthate multiple interactions EXP 6480464 Tamoxifen promotes the reaction [testosterone enanthate results in increased expression of CYP2C11 protein] CTD PMID:8573203 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of CYP2C protein more ... CTD PMID:12629582 more ... tetrachloromethane multiple interactions EXP 6480464 Curcumin inhibits the reaction [Carbon Tetrachloride results in decreased activity of CYP2C9 protein] CTD PMID:16288784 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of CYP2C11 mRNA CTD PMID:31150632 tetrachloromethane affects expression EXP 6480464 Carbon Tetrachloride affects the expression of CYP2C mRNA CTD PMID:12734012 and PMID:17805973 tetrachloromethane decreases activity EXP 6480464 Carbon Tetrachloride results in decreased activity of CYP2C11 protein and Carbon Tetrachloride results in decreased activity of CYP2C9 protein CTD PMID:14706259 and PMID:16288784 thiabendazole decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Thiabendazole results in decreased activity of CYP2C9 protein CTD PMID:11124226 thiacloprid increases expression ISO CYP2C9 (Homo sapiens) 6480464 thiacloprid results in increased expression of CYP2C9 protein CTD PMID:32201337 thiacloprid multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [clothianidin co-treated with thiacloprid] results in increased expression of CYP2C9 protein CTD PMID:32201337 thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of CYP2C11 mRNA and Thioacetamide results in decreased expression of CYP2C9 mRNA CTD PMID:23411599 and PMID:37008694 thioacetamide multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CYP2C mRNA CTD PMID:28943392 Thiocoraline affects metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein affects the metabolism of thiocoraline CTD PMID:15122071 thioridazine multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Thioridazine CTD PMID:23397584 thioridazine decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Thioridazine results in decreased activity of CYP2C9 protein CTD PMID:15135088 ticlopidine decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Ticlopidine results in decreased activity of CYP2C9 protein CTD PMID:21915887 ticlopidine multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased oxidation of and results in increased cleavage of Ticlopidine metabolite more ... CTD PMID:19170597 and PMID:21915887 tienilic acid decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Ticrynafen results in decreased activity of CYP2C9 protein CTD PMID:15860655 more ... tienilic acid affects metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein affects the metabolism of Ticrynafen CTD PMID:21321060 tienilic acid increases response to substance ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased susceptibility to Ticrynafen CTD PMID:28762043 tienilic acid multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [[Ticrynafen results in decreased activity of CYP2C9 protein] which affects the metabolism of Diclofenac] which affects the abundance of 4'-hydroxydiclofenac more ... CTD PMID:16049126 and PMID:31854189 tienilic acid increases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased metabolism of Ticrynafen CTD PMID:12464242 tolbutamide increases hydrolysis ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased hydrolysis of Tolbutamide CTD PMID:11377097 tolbutamide increases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased metabolism of Tolbutamide CTD PMID:10208645 more ... tolbutamide multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [CYP2C9 protein results in increased metabolism of Tolbutamide] which results in increased chemical synthesis of 4'-hydroxytolbutamide more ... CTD PMID:10611138 more ... tolbutamide increases chemical synthesis ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased chemical synthesis of Tolbutamide metabolite CTD PMID:23850985 tolbutamide decreases hydroxylation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 gene SNP results in decreased hydroxylation of Tolbutamide CTD PMID:9170147 tolbutamide affects metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 gene polymorphism affects the metabolism of Tolbutamide more ... CTD PMID:11875364 more ... tolbutamide increases hydroxylation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased hydroxylation of Tolbutamide CTD PMID:10611138 more ... tolbutamide affects hydroxylation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein affects the hydroxylation of Tolbutamide CTD PMID:9170147 tolbutamide decreases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 gene polymorphism results in decreased metabolism of Tolbutamide CTD PMID:10208645 and PMID:9110362 tolbutamide increases metabolic processing ISO CYP2C18 (Homo sapiens) 6480464 CYP2C18 results in increased metabolism of Tolbutamide CTD PMID:15301741 toluene increases oxidation EXP 6480464 CYP2C11 protein results in increased oxidation of Toluene CTD PMID:1994898 toluene affects expression EXP 6480464 Toluene affects the expression of CYP2C mRNA CTD PMID:18653662 toluene affects metabolic processing EXP 6480464 CYP2C11 protein affects the metabolism of Toluene CTD PMID:8620572 toluene multiple interactions EXP 6480464 CYP2C11 protein affects the reaction [Benzene results in increased metabolism of Toluene] more ... CTD PMID:1994898 and PMID:8620572 torasemide affects metabolic processing EXP 6480464 CYP2C11 protein affects the metabolism of Torsemide CTD PMID:15890479 torasemide increases hydroxylation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased hydroxylation of Torsemide CTD PMID:9110362 torasemide increases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased metabolism of Torsemide CTD PMID:19082874 trans-1,2-dichloroethene decreases expression EXP 6480464 1 and 2-dichloroethylene results in decreased expression of CYP2C11 protein CTD PMID:9493318 trans-1,2-dichloroethene decreases activity EXP 6480464 1 and 2-dichloroethylene results in decreased activity of CYP2C11 protein CTD PMID:9493318 trans-cinnamic acid decreases activity ISO CYP2C9 (Homo sapiens) 6480464 cinnamic acid analog results in decreased activity of CYP2C9 protein CTD PMID:15072549 tranylcypromine multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 Tranylcypromine affects the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid] CTD PMID:24120545 Tributyltin oxide increases expression EXP 6480464 bis(tri-n-butyltin)oxide results in increased expression of CYP2C mRNA CTD PMID:17553608 trichloroethene multiple interactions EXP 6480464 CYP2C11 protein affects the reaction [Trichloroethylene results in increased metabolism of Toluene] CTD PMID:8620572 triclosan increases expression ISO CYP2C18 (Homo sapiens) 6480464 Triclosan results in increased expression of CYP2C11 mRNA CTD PMID:29849464 triclosan increases expression ISO CYP2C9 (Homo sapiens) 6480464 Triclosan results in increased expression of CYP2C22 mRNA and Triclosan results in increased expression of CYP2C9 mRNA CTD PMID:29849464 triflumuron increases metabolic processing ISO CYP2C18 (Homo sapiens) 6480464 CYP2C18 protein results in increased metabolism of triflumuron CTD PMID:31082524 triflumuron increases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased metabolism of triflumuron CTD PMID:31082524 trimethylarsine oxide increases expression EXP 6480464 trimethylarsine oxide results in increased expression of CYP2C11 mRNA CTD PMID:17481689 Triptolide decreases expression EXP 6480464 triptolide results in decreased expression of CYP2C11 protein CTD PMID:32519852 troglitazone decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Troglitazone results in decreased activity of CYP2C9 protein CTD PMID:12642470 troglitazone multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Troglitazone CTD PMID:23397584 tryptamines multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 [Tryptamines analog results in decreased activity of CYP2C9 protein] which results in decreased metabolism of Diclofenac CTD PMID:26599973 tryptamines decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Tryptamines analog results in decreased activity of CYP2C9 protein CTD PMID:26599973 uranium atom multiple interactions EXP 6480464 [Acetaminophen co-treated with Uranium analog] results in decreased expression of CYP2C11 mRNA CTD PMID:17126469 ursodeoxycholic acid multiple interactions EXP 6480464 Ursodeoxycholic Acid inhibits the reaction [Deoxycholic Acid results in decreased expression of CYP2C11 protein] CTD PMID:10453939 valproic acid increases expression ISO CYP2C9 (Homo sapiens) 6480464 Valproic Acid results in increased expression of CYP2C9 mRNA CTD PMID:25084468 valproic acid increases response to substance ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 polymorphism results in increased susceptibility to Valproic Acid CTD PMID:20398172 valproic acid increases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased metabolism of Valproic Acid CTD PMID:16945988 and PMID:20602621 valproic acid decreases expression ISO CYP2C9 (Homo sapiens) 6480464 Valproic Acid results in decreased expression of CYP2C9 mRNA CTD PMID:29154799 and PMID:29501571 valsartan affects metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 polymorphism affects the metabolism of Valsartan CTD PMID:34998819 vancomycin multiple interactions EXP 6480464 [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP2C11 mRNA CTD PMID:30545405 verapamil multiple interactions EXP 6480464 Verapamil inhibits the reaction [Cyclosporine results in increased expression of CYP2C11 protein] CTD PMID:28899749 vincristine increases response to substance ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 gene SNP results in increased susceptibility to Vincristine CTD PMID:21245421 vitamin K multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 gene polymorphism affects the reaction [Vitamin K affects the susceptibility to Warfarin] CTD PMID:27462768 voriconazole affects metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein affects the metabolism of Voriconazole CTD PMID:15914520 voriconazole decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Voriconazole results in decreased activity of CYP2C9 protein CTD PMID:15328084 and PMID:15914520 warfarin increases metabolic processing EXP 6480464 CYP2C11 protein results in increased metabolism of Warfarin CTD PMID:30724651 warfarin decreases hydroxylation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 gene polymorphism results in decreased hydroxylation of Warfarin CTD PMID:11455026 warfarin increases hydrolysis ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased hydrolysis of Warfarin CTD PMID:9698079 warfarin affects hydroxylation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein affects the hydroxylation of Warfarin CTD PMID:10613612 warfarin decreases activity ISO CYP2C9 (Homo sapiens) 6480464 Warfarin results in decreased activity of CYP2C9 protein CTD PMID:18420780 warfarin decreases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 gene polymorphism results in decreased metabolism of Warfarin CTD PMID:20073138 warfarin affects metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 enhancer polymorphism affects the metabolism of Warfarin more ... CTD PMID:11307788 more ... warfarin affects abundance ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 gene polymorphism affects the abundance of Warfarin CTD PMID:25986145 warfarin affects hydrolysis ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 gene polymorphism affects the hydrolysis of Warfarin CTD PMID:9698079 warfarin increases metabolic processing ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased metabolism of Warfarin CTD PMID:12464242 more ... warfarin increases response to substance ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 gene mutant form results in increased susceptibility to Warfarin more ... CTD PMID:11794436 more ... warfarin decreases response to substance ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 gene polymorphism results in decreased susceptibility to Warfarin CTD PMID:18030307 and PMID:18034619 warfarin affects response to substance ISO CYP2C18 (Homo sapiens) 6480464 CYP2C18 gene polymorphism affects the susceptibility to Warfarin and CYP2C18 protein affects the susceptibility to Warfarin CTD PMID:19752777 warfarin multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 10-hydroxywarfarin inhibits the reaction [[CYP2C9 protein results in increased hydroxylation of Warfarin] which results in increased chemical synthesis of 7-hydroxywarfarin] more ... CTD PMID:10613612 more ... warfarin affects response to substance ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 affects the susceptibility to Warfarin more ... CTD PMID:11127854 more ... warfarin increases hydroxylation ISO CYP2C9 (Homo sapiens) 6480464 CYP2C9 protein results in increased hydroxylation of Warfarin CTD PMID:11455026 more ... zafirlukast multiple interactions ISO CYP2C9 (Homo sapiens) 6480464 zafirlukast inhibits the reaction [CYP2C9 protein affects the metabolism of Diclofenac] and zafirlukast inhibits the reaction [CYP2C9 protein results in increased metabolism of Tolbutamide] CTD PMID:15370959 and PMID:16081671 zafirlukast decreases activity ISO CYP2C9 (Homo sapiens) 6480464 zafirlukast results in decreased activity of CYP2C9 protein CTD PMID:15370959 zinc atom multiple interactions EXP 6480464 Zinc deficiency results in decreased expression of and results in decreased activity of CYP2C11 protein CTD PMID:11705462 zinc atom decreases expression EXP 6480464 Zinc deficiency results in decreased expression of CYP2C11 mRNA CTD PMID:11705462 zinc(0) multiple interactions EXP 6480464 Zinc deficiency results in decreased expression of and results in decreased activity of CYP2C11 protein CTD PMID:11705462 zinc(0) decreases expression EXP 6480464 Zinc deficiency results in decreased expression of CYP2C11 mRNA CTD PMID:11705462 zoledronic acid increases expression ISO CYP2C9 (Homo sapiens) 6480464 Zoledronic Acid results in increased expression of CYP2C9 mRNA CTD PMID:24714768