Ptpra (protein tyrosine phosphatase, receptor type, A)

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Gene: Ptpra (protein tyrosine phosphatase, receptor type, A) Rattus norvegicus

Analyze

Symbol:

Ptpra

Name:

protein tyrosine phosphatase, receptor type, A

RGD ID:

3450

Description:

Exhibits protein tyrosine phosphatase activity. Involved in oligodendrocyte differentiation and positive regulation of oligodendrocyte differentiation. Localizes to intracellular membrane-bounded organelle and plasma membrane. Orthologous to human PTPRA (protein tyrosine phosphatase receptor type A); PARTICIPATES IN insulin signaling pathway; INTERACTS WITH atrazine; bis(2-chloroethyl) sulfide; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

LRP; MGC93561; protein tyrosine phosphatase alpha; protein-tyrosine phosphatase alpha; R-PTP-alpha; receptor-type tyrosine-protein phosphatase alpha

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Allele / Splice:

Ptpra^{Tn(sb-T2/Bart3)2.261Mcwi}

Genetic Models:

F344-Ptpra^{Tn(sb-T2/Bart3)2.261Mcwi}

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	3	117,650,146 - 117,759,744 (+)	NCBI
Rnor_6.0 Ensembl	3	122,976,104 - 123,084,863 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	3	122,976,066 - 123,084,585 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	3	129,475,237 - 129,582,992 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	118,061,713 - 118,171,300 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	3	118,022,615 - 118,077,164 (+)	NCBI
Celera	3	116,464,194 - 116,570,590 (+)	NCBI		Celera
Cytogenetic Map	3	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Myocardial Ischemia (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(S)-nicotine (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

4-hydroxynon-2-enal (ISO)

acrolein (ISO)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

Aroclor 1254 (ISO)

atrazine (EXP,ISO)

benzo[a]pyrene (ISO)

bis(2-chloroethyl) sulfide (EXP)

bisphenol A (EXP)

casticin (ISO)

cisplatin (ISO)

cocaine (ISO)

copper(II) sulfate (ISO)

dibutyl phthalate (EXP)

endosulfan (EXP)

ethanol (ISO)

fipronil (EXP)

folic acid (ISO)

geldanamycin (ISO)

genistein (ISO)

hydrogen peroxide (ISO)

Mecamylamine (ISO)

menadione (ISO)

methylmercury chloride (ISO)

N-methyl-N'-nitro-N-nitrosoguanidine (ISO)

nickel sulfate (ISO)

nicotine (ISO)

ozone (ISO)

resveratrol (ISO)

sodium arsenite (ISO)

sodium fluoride (ISO)

tamoxifen (ISO)

thapsigargin (ISO)

thimerosal (ISO)

trichloroethene (ISO)

trichostatin A (ISO)

tubocurarine (ISO)

urethane (ISO)

valproic acid (ISO)

vinclozolin (EXP)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

insulin receptor signaling pathway (IEA,ISO)

integrin-mediated signaling pathway (IEA,ISO,ISS)

modulation of chemical synaptic transmission (IEA,ISO)

oligodendrocyte differentiation (IEP)

peptidyl-tyrosine dephosphorylation (IEA)

positive regulation of oligodendrocyte differentiation (IMP)

protein dephosphorylation (IBA)

protein phosphorylation (IEA,ISO)

regulation of focal adhesion assembly (IEA,ISO,ISS)

Cellular Component

focal adhesion (IEA,ISO,ISS)

integral component of membrane (IEA)

integral component of synaptic membrane (IEA,ISO)

intracellular membrane-bounded organelle (IDA)

membrane (ISO)

plasma membrane (IDA,IEA)

receptor complex (IEA)

Schaffer collateral - CA1 synapse (IEA,ISO)

Molecular Function

protein binding (IPI,ISO)

protein tyrosine phosphatase activity (IBA,IDA,IEA,ISO,ISS)

protein-containing complex binding (IDA)

Molecular Pathway Annotations Click to see Annotation Detail View

insulin signaling pathway (ISO)

References

References - curated


1.	Calera MR, etal., J Biol Chem. 2000 Mar 3;275(9):6308-12.
2.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	GOA data from the GO Consortium
4.	Helmke S, etal., J Cell Sci. 1998 Aug;111 ( Pt 16):2465-75.
5.	Lei G, etal., EMBO J. 2002 Jun 17;21(12):2977-89.
6.	Lin D, etal., J Biol Chem. 2008 Mar 21;283(12):7674-81. Epub 2008 Jan 22.
7.	MGD data from the GO Consortium
8.	Moriyama T, etal., Biochem Biophys Res Commun 1992 Oct 15;188(1):34-9.
9.	NCBI rat LocusLink and RefSeq merged data July 26, 2002
10.	Pipeline to import Pathway Interaction Database annotations from NCI into RGD
11.	RGD automated data pipeline
12.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13.	RGD automated import pipeline for gene-chemical interactions
14.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
15.	Su J, etal., J Biol Chem. 1994 Jul 22;269(29):18731-4.
16.	Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
17.	Wang PS, etal., J Biol Chem. 2009 Oct 6.

Additional References at PubMed

PMID:12826681	PMID:12912911	PMID:14733908	PMID:15978577	PMID:16899073	PMID:18768480	PMID:20458337	PMID:23382219

Genomics

Comparative Map Data

Ptpra
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	3	117,650,146 - 117,759,744 (+)	NCBI
Rnor_6.0 Ensembl	3	122,976,104 - 123,084,863 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	3	122,976,066 - 123,084,585 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	3	129,475,237 - 129,582,992 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	118,061,713 - 118,171,300 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	3	118,022,615 - 118,077,164 (+)	NCBI
Celera	3	116,464,194 - 116,570,590 (+)	NCBI		Celera
Cytogenetic Map	3	q36	NCBI

PTPRA
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	20	2,864,184 - 3,039,076 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	20	2,864,184 - 3,038,669 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	20	2,844,830 - 3,019,315 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	2,792,841 - 2,967,315 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	20	2,851,852 - 2,967,314	NCBI
Celera	20	2,907,196 - 3,081,302 (+)	NCBI
Cytogenetic Map	20	p13	NCBI
HuRef	20	2,793,748 - 2,965,653 (+)	NCBI		HuRef
CHM1_1	20	2,844,843 - 3,014,144 (+)	NCBI		CHM1_1

Ptpra
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	130,292,198 - 130,396,220 (+)	NCBI	GRCm39		mm39
GRCm39 Ensembl	2	130,292,198 - 130,398,044 (+)	Ensembl
GRCm38	2	130,450,278 - 130,554,300 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	130,450,278 - 130,556,124 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	130,276,014 - 130,380,036 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	2	130,194,915 - 130,245,464 (+)	NCBI			mm8
Celera	2	131,674,730 - 131,778,720 (+)	NCBI		Celera
Cytogenetic Map	2	F1	NCBI
cM Map	2	63.23	NCBI

Ptpra
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955415	13,819,717 - 13,967,068 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955415	13,819,934 - 13,967,068 (+)	NCBI	ChiLan1.0	ChiLan1.0

PTPRA
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	20	2,726,657 - 2,888,195 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	2,801,905 - 2,888,195 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	20	2,962,701 - 3,125,282 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

PTPRA
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	18,224,355 - 18,395,650 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	18,224,801 - 18,296,350 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	18,052,684 - 18,223,899 (-)	NCBI
ROS_Cfam_1.0	24	18,643,403 - 18,815,534 (-)	NCBI
UMICH_Zoey_3.1	24	18,236,577 - 18,408,752 (-)	NCBI
UNSW_CanFamBas_1.0	24	18,349,051 - 18,519,508 (-)	NCBI
UU_Cfam_GSD_1.0	24	18,677,051 - 18,848,067 (-)	NCBI

Ptpra
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	167,313,690 - 167,441,022 (-)	NCBI
SpeTri2.0	NW_004936485	15,745,054 - 15,872,377 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PTPRA
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	32,633,612 - 32,797,104 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	17	32,638,494 - 32,797,110 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	37,008,987 - 37,167,722 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PTPRA
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	33,559,634 - 33,724,446 (+)	NCBI
ChlSab1.1 Ensembl	2	33,559,697 - 33,722,137 (+)	Ensembl
Vero_WHO_p1.0	NW_023666071	10,789,232 - 10,956,158 (-)	NCBI

Ptpra
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624741	3,997,853 - 4,155,130 (+)	NCBI

Position Markers

BE108511

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	3	123,084,673 - 123,084,866	NCBI	Rnor6.0
Rnor_5.0	3	129,582,801 - 129,582,994	UniSTS	Rnor5.0
RGSC_v3.4	3	118,171,401 - 118,171,594	UniSTS	RGSC3.4
Celera	3	116,570,691 - 116,570,884	UniSTS
RH 3.4 Map	3	1001.2	UniSTS
Cytogenetic Map	3	q36	UniSTS

AU047115

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	3	123,058,055 - 123,058,320	NCBI	Rnor6.0
Rnor_5.0	3	129,556,183 - 129,556,448	UniSTS	Rnor5.0
RGSC_v3.4	3	118,143,790 - 118,144,055	UniSTS	RGSC3.4
Celera	3	116,545,174 - 116,545,439	UniSTS
Cytogenetic Map	3	q36	UniSTS

RH134950

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	3	123,037,794 - 123,037,989	NCBI	Rnor6.0
Rnor_5.0	3	129,535,922 - 129,536,117	UniSTS	Rnor5.0
RGSC_v3.4	3	118,123,530 - 118,123,725	UniSTS	RGSC3.4
Celera	3	116,524,913 - 116,525,108	UniSTS
RH 3.4 Map	3	1000.7	UniSTS
Cytogenetic Map	3	q36	UniSTS

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	10639528	127023997	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	10639528	127023997	Rat
737818	Hcar12	Hepatocarcinoma resistance QTL 12	2.6		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	3	30114912	123700444	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	30846101	172879276	Rat
1358362	Srcrt2	Stress Responsive Cort QTL 2	2.78		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	39248391	140271184	Rat
2301970	Bw81	Body weight QTL 81	5.19		body mass (VT:0001259)	body weight (CMO:0000012)	3	43295930	163640485	Rat
2301971	Cm71	Cardiac mass QTL 71	4.63		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	3	43295930	163640485	Rat
1581503	Cm58	Cardiac mass QTL 58	2.7	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	45406058	127023997	Rat
1559282	Emca5	Estrogen-induced mammary cancer QTL 5	3.9		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	3	45406058	177699992	Rat
2292591	Esta4	Estrogen-induced thymic atrophy QTL 4			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	3	48561928	155263151	Rat
631665	Bw8	Body weight QTL 8	5.5		body mass (VT:0001259)	body weight (CMO:0000012)	3	51821836	124513579	Rat
1581568	Rf53	Renal function QTL 53			total urine protein amount (VT:0000032)	urine protein excretion rate to body weight ratio (CMO:0001099)	3	58204463	170534769	Rat
8662816	Vetf4	Vascular elastic tissue fragility QTL 4	4		renal artery integrity trait (VT:0010642)	number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)	3	61241033	165369047	Rat
1300111	Rf12	Renal function QTL 12	3.78		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	3	62922868	127023997	Rat
12879848	Bw181	Body weght QTL 181		0.015	body mass (VT:0001259)	body weight (CMO:0000012)	3	72672290	127023997	Rat
2301414	Kidm37	Kidney mass QTL 37		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	72973445	127023997	Rat
1600376	Arunc5	Aerobic running capacity QTL 5		0.21	exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	3	78700444	123700444	Rat
1581546	Pur13	Proteinuria QTL 13	2.93	0.0335	total urine protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	3	81136227	154416635	Rat
7387306	Bw124	Body weight QTL 124	3.2	0.0003	body mass (VT:0001259)	body weight (CMO:0000012)	3	88910015	133910015	Rat
631649	Bp123	Blood pressure QTL 123	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	94788365	139788365	Rat
8694437	Bw167	Body weight QTL 167	22.46	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	3	97009185	142009185	Rat
631841	Niddm39	Non-insulin dependent diabetes mellitus QTL 39	3.36		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	99465522	168732722	Rat
724532	Cm17	Cardiac mass QTL 17	2		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	3	101058963	146058963	Rat
2293087	Iddm27	Insulin dependent diabetes mellitus QTL 27	2.68		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	102152812	155263151	Rat
1354611	Despr2	Despair related QTL 2	3.03	0.0028	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	3	102466149	147466149	Rat
2312659	Slep7	Serum leptin concentration QTL 7		0.001	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	3	103141814	176418101	Rat
2312670	Bw94	Body weight QTL 94		0.01	inguinal fat pad mass (VT:0010424)	inguinal fat pad weight to body weight ratio (CMO:0001253)	3	103141814	176418101	Rat
2312673	Scl63	Serum cholesterol level QTL 63		0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	3	103141814	176418101	Rat
2302373	Gluco39	Glucose level QTL 39	5.01		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	3	103141944	170934860	Rat
619618	Rf3	Renal disease susceptibility QTL 3	6.5	0.001	urine albumin amount (VT:0002871)	urine albumin excretion rate to body weight ratio (CMO:0001270)	3	114376250	159376250	Rat
1331758	Bp207	Blood pressure QTL 207	2.848		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	117303473	141971336	Rat
1578754	Stresp16	Stress response QTL 16	4	0.001	blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	3	119471263	164471263	Rat
1358204	Insglur1	Insulin/glucose ratio QTL 1	3.8		blood glucose amount (VT:0000188)	serum glucose level (CMO:0000543)	3	120917788	141971336	Rat
1358204	Insglur1	Insulin/glucose ratio QTL 1	3.8		blood glucose amount (VT:0000188)	serum insulin level (CMO:0000358)	3	120917788	141971336	Rat

Genetic Models

This gene Ptpra is modified in the following models/strains

F344-Ptpra^{Tn(sb-T2/Bart3)2.261Mcwi}

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	249
Count of miRNA genes:	171
Interacting mature miRNAs:	192
Transcripts:	ENSRNOT00000055801
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	43	56	40	19	40	6	6	74	35	38	11	6
Low			1	1		1	2	5			3		2
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_012763	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006235006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006235007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039104340	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC081828	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000118	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	L01702	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U57500	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000055801 ⟹ ENSRNOP00000052657

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	3	122,976,104 - 123,084,569 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000080379 ⟹ ENSRNOP00000069583

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	3	123,031,307 - 123,084,863 (+)	Ensembl

RefSeq Acc Id:

NM_012763 ⟹ NP_036895

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	117,650,183 - 117,759,731 (+)	NCBI
Rnor_6.0	3	122,976,104 - 123,084,572 (+)	NCBI
Rnor_5.0	3	129,475,237 - 129,582,992 (+)	NCBI
RGSC_v3.4	3	118,061,713 - 118,171,300 (+)	RGD
Celera	3	116,464,194 - 116,570,590 (+)	RGD

Sequence:

show sequence

CGGCGAGTGAGGCGCTGACAGGGACTCACGGGGGCATCTTGCACAGACCCCTGGACCACGCCGC
CATCGCAGCCTCCCGCCCAGTCCTCTCTCTGCTGCTTCTCCTCGCCATGGAGGCGAGGCCGCCG
CCGCCGCCGCGGGGCTTCGAGCAGCGGACCGGGCGGCGGCCCTGAGGGGAGCGGCGGGCCGAGA
CGCCGCCGCGGTGCTGAGGCGGAGCTGCCGTGCGCGTCCCCCGCGGTCCCGCCCAGCGCCGGGC
TCGGTCAGCATGGATTCCTGGTTCATTCTTATCCTGTTTGGCAGTGGTCTAATACACATTAGTG
CCAACAACACTACTACAGTTTCACCTTCTTTAGGAACTACAAGATTAATTAAAACATCAACAAC
AGAATCGGCTAAGGAAGAGAATAAAACTTCAAATTCAACCTCTTCAGTAATTTCTCTTTCTGTG
ACACCAACATTCAGCCCAAATCTAACTCTGGAACCCACCTATGTGACTACTGTTAATTCTTCAC
ACTCTGACAATGGGACCAAGAGAGCAGCCAGCACGGAATCTGGAGGCACTACCATTTCACCAAA
CGGAACATACGGAACATGGCTTACTGATAACCAGTTCACGGATGCCAGAACAGAACCCTGGGAG
GGGAATTCCAGCACTGCAGCAACCACTCCAGAAACCTTCCCCCCTGCAGATGAGACACCAATCA
TTGCGGTGATGGTGGCCCTGTCCTCTCTGCTAGTAATTGTGTTTATTATTATAGTTCTGTACAT
GTTAAGGTTTAAGAAATACAAGCAAGCTGGGAGCCATTCCAATTCTTTCCGCCTGTCAAATGGC
CGCACAGAGGATGTGGAGCCCCAAAGTGTACCACTTCTGGCCAGGTCCCCGAGCACCAACAGGA
AGTTCCCACCACTGCCTGTGGACAAGCTGGAAGAGGAGATTAACCGGAGAATGGCTGATGACAA
TAAGCTCTTCAGAGAGGAATTCAACGCCCTCCCTGCCTGTCCAATCCAGGCCACCTGTGAGGCT
GCCTCCAAGGAAGAAAACAAGGAAAAAAACCGATATGTAAACATCCTGCCTTATGACCACTCCA
GAGTGCACCTGACGCCTGTGGAAGGGGTTCCAGATTCTGATTACATCAACGCCTCATTCATTAA
TGGCTACCAGGAAAAGAACAAATTCATTGCTGCACAAGGACCAAAAGAAGAAACGGTGAATGAT
TTCTGGAGAATGATATGGGAACAGAACACAGCCACCATTGTCATGGTGACCAACCTGAAGGAGA
GAAAGGAGTGTAAATGTGCCCAGTATTGGCCAGACCAAGGCTGCTGGACCTATGGGAATGTCCG
TGTGTCTGTCGAGGATGTGACTGTTCTGGTGGACTACACAGTACGGAAATTCTGCATCCAGCAG
GTGGGCGACGTCACCAACAGGAAGCCACAGCGCCTCATCACTCAGTTCCATTTCACCAGCTGGC
CAGACTTTGGGGTGCCTTTTACCCCAATTGGCATGCTCAAGTTCCTCAAGAAGGTGAAAGCCTG
TAACCCTCAGTATGCAGGGGCTATCGTGGTCCACTGCAGTGCAGGTGTAGGGCGCACTGGCACC
TTTGTTGTCATCGATGCCATGCTGGACATGATGCATTCGGAGCGCAAAGTGGATGTATATGGGT
TTGTGAGCCGGATCCGGGCCCAGCGCTGCCAGATGGTCCAGACAGACATGCAGTACGTCTTCAT
ATACCAGGCCCTTCTGGAGCATTATCTATATGGCGACACAGAGCTGGAAGTGACTTCCCTAGAC
ACCCACCTGCAAAAAATTTATAACAAGATCCCAGGAACTAGCAACAATGGACTAGAGGAGGAAT
TTAAGAAATTAACTTCAATCAAAATCCAAAATGACAAGATGCGTACGGGAAACCTTCCAGCCAA
CATGAAGAAGAACCGAGTTTTACAGATCATTCCATATGAATTTAACAGAGTGATCATTCCAGTC
AAACGGGGCGAAGAGAACACAGACTATGTGAACGCATCCTTCATTGATGGCTACCGGCAGAAAG
ATTCCTACATCGCCAGCCAGGGCCCTCTTCTCCACACAATTGAGGACTTCTGGCGAATGATCTG
GGAATGGAAGTCCTGCTCCATTGTAATGCTAACAGAACTGGAAGAAAGAGGCCAGGAGAAGTGT
GCCCAGTACTGGCCATCTGATGGCCTGGTGTCCTATGGAGACATCACAGTTGAGCTGAAGAAGG
AGGAGGAATGTGAGAGCTACACTGTCCGAGACCTCCTGGTCACCAACACCAGGGAGAACAAGAG
TCGGCAGATCCGGCAGTTCCACTTCCACGGCTGGCCTGAGGTGGGCATCCCCAGCGATGGGAAG
GGTATGATCAACATCATTGCAGCAGTGCAGAAGCAGCAGCAGCAGTCAGGGAACCATCCCATCA
CTGTGCACTGCAGTGCCGGGGCAGGACGGACAGGGACCTTTTGTGCCTTGAGCACAGTCCTGGA
GCGCGTGAAAGCAGAAGGAATTTTGGATGTCTTCCAAACTGTCAAGAGCCTGCGGCTGCAGAGG
CCACACATGGTCCAGACACTGGAACAGTATGAATTCTGCTACAAGGTGGTACAGGAGTACATCG
ATGCCTTCTCAGATTATGCCAACTTCAAGTGACAGGGGACAAGGCCCACAGACAGGAGAATTGC
CTTTAATATTTTGTAATATTCTGTTTTGTTAATATACCCAAAATTGTATATATCTTATAACTGT
TTTAGAAATGGCACATAGGCTTCTATTACCTATTAGGTGGAGATTTTGTATGTAAATGTGTTAG
CACTATAGTCCTTTTCCAGTGTTTTATTGGGGAATTAAATAGTGTGATATTTGAGTTGATTTAA
TGAAGTCCTTAGCCTGGAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006235006 ⟹ XP_006235068

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	117,650,146 - 117,759,744 (+)	NCBI
Rnor_6.0	3	122,976,066 - 123,084,585 (+)	NCBI
Rnor_5.0	3	129,475,237 - 129,582,992 (+)	NCBI

Sequence:

show sequence

AGCGCCTTACAGCCCAGGCCGCGTTGGGAGTGAGGCTGCGGCGAGTGAGGCGCTGACAGGGACT
CACGGGGGCATCTTGCACAGACCCCTGGACCACGCCGCCATCGCAGCCTCCCGCCCAGTCCTCT
CTCTGCTGCTTCTCCTCGCCATGGAGGCGAGGCCGCCGCCGCCGCCGCGGGGCTTCGAGCAGCG
GACCGGGCGGCGGCCCTGAGGGGAGCGGCGGGCCGAGACGCCGCCGCGGTGCTGAGGCGGAGCT
GCCGTGCGCGTCCCCCGCGGTCCCGCCCAGCGCCGGGCTCGGTCAGCATGGATTCCTGGTTCAT
TCTTATCCTGTTTGGCAGTGGTCTAATACACATTAGTGCCAACAACACTACTACAGTTTCACCT
TCTTTAGGAACTACAAGATTAATTAAAACATCAACAACAGAATCGGCTAAGGAAGAGAATAAAA
CTTCAAATTCAACCTCTTCAGTAATTTCTCTTTCTGTGACACCAACATTCAGCCCAAATCTAAC
TCTGGAACCCACCTATGTGACTACTGTTAATTCTTCACACTCTGACAATGGGACCAAGAGAGCA
GCCAGCACGGAATCTGGAGGCACTACCATTTCACCAAACGGAACATACGGAACATGGCTTACTG
ATAACCAGTTCACGGATGCCAGAACAGAACCCTGGGAGGGGAATTCCAGCACTGCAGCAACCAC
TCCAGAAACCTTCCCCCCTGCAGGTAATTCTGACTCAAAAGACAGGAGAGATGAGACACCAATC
ATTGCGGTGATGGTGGCCCTGTCCTCTCTGCTAGTAATTGTGTTTATTATTATAGTTCTGTACA
TGTTAAGGTTTAAGAAATACAAGCAAGCTGGGAGCCATTCCAATTCTTTCCGCCTGTCAAATGG
CCGCACAGAGGATGTGGAGCCCCAAAGTGTACCACTTCTGGCCAGGTCCCCGAGCACCAACAGG
AAGTTCCCACCACTGCCTGTGGACAAGCTGGAAGAGGAGATTAACCGGAGAATGGCTGATGACA
ATAAGCTCTTCAGAGAGGAATTCAACGCCCTCCCTGCCTGTCCAATCCAGGCCACCTGTGAGGC
TGCCTCCAAGGAAGAAAACAAGGAAAAAAACCGATATGTAAACATCCTGCCTTATGACCACTCC
AGAGTGCACCTGACGCCTGTGGAAGGGGTTCCAGATTCTGATTACATCAACGCCTCATTCATTA
ATGGCTACCAGGAAAAGAACAAATTCATTGCTGCACAAGGACCAAAAGAAGAAACGGTGAATGA
TTTCTGGAGAATGATATGGGAACAGAACACAGCCACCATTGTCATGGTGACCAACCTGAAGGAG
AGAAAGGAGTGTAAATGTGCCCAGTATTGGCCAGACCAAGGCTGCTGGACCTATGGGAATGTCC
GTGTGTCTGTCGAGGATGTGACTGTTCTGGTGGACTACACAGTACGGAAATTCTGCATCCAGCA
GGTGGGCGACGTCACCAACAGGAAGCCACAGCGCCTCATCACTCAGTTCCATTTCACCAGCTGG
CCAGACTTTGGGGTGCCTTTTACCCCAATTGGCATGCTCAAGTTCCTCAAGAAGGTGAAAGCCT
GTAACCCTCAGTATGCAGGGGCTATCGTGGTCCACTGCAGTGCAGGTGTAGGGCGCACTGGCAC
CTTTGTTGTCATCGATGCCATGCTGGACATGATGCATTCGGAGCGCAAAGTGGATGTATATGGG
TTTGTGAGCCGGATCCGGGCCCAGCGCTGCCAGATGGTCCAGACAGACATGCAGTACGTCTTCA
TATACCAGGCCCTTCTGGAGCATTATCTATATGGCGACACAGAGCTGGAAGTGACTTCCCTAGA
CACCCACCTGCAAAAAATTTATAACAAGATCCCAGGAACTAGCAACAATGGACTAGAGGAGGAA
TTTAAGAAATTAACTTCAATCAAAATCCAAAATGACAAGATGCGTACGGGAAACCTTCCAGCCA
ACATGAAGAAGAACCGAGTTTTACAGATCATTCCATATGAATTTAACAGAGTGATCATTCCAGT
CAAACGGGGCGAAGAGAACACAGACTATGTGAACGCATCCTTCATTGATGGCTACCGGCAGAAA
GATTCCTACATCGCCAGCCAGGGCCCTCTTCTCCACACAATTGAGGACTTCTGGCGAATGATCT
GGGAATGGAAGTCCTGCTCCATTGTAATGCTAACAGAACTGGAAGAAAGAGGCCAGGAGAAGTG
TGCCCAGTACTGGCCATCTGATGGCCTGGTGTCCTATGGAGACATCACAGTTGAGCTGAAGAAG
GAGGAGGAATGTGAGAGCTACACTGTCCGAGACCTCCTGGTCACCAACACCAGGGAGAACAAGA
GTCGGCAGATCCGGCAGTTCCACTTCCACGGCTGGCCTGAGGTGGGCATCCCCAGCGATGGGAA
GGGTATGATCAACATCATTGCAGCAGTGCAGAAGCAGCAGCAGCAGTCAGGGAACCATCCCATC
ACTGTGCACTGCAGTGCCGGGGCAGGACGGACAGGGACCTTTTGTGCCTTGAGCACAGTCCTGG
AGCGCGTGAAAGCAGAAGGAATTTTGGATGTCTTCCAAACTGTCAAGAGCCTGCGGCTGCAGAG
GCCACACATGGTCCAGACACTGGAACAGTATGAATTCTGCTACAAGGTGGTACAGGAGTACATC
GATGCCTTCTCAGATTATGCCAACTTCAAGTGACAGGGGACAAGGCCCACAGACAGGAGAATTG
CCTTTAATATTTTGTAATATTCTGTTTTGTTAATATACCCAAAATTGTATATATCTTATAACTG
TTTTAGAAATGGCACATAGGCTTCTATTACCTATTAGGTGGAGATTTTGTATGTAAATGTGTTA
GCACTATAGTCCTTTTCCAGTGTTTTATTGGGGAATTAAATAGTGTGATATTTGAGTTGATTTA
ATGAAGTCCTTAGCCTGGAAATTGGGCCAGATTA

hide sequence

RefSeq Acc Id:

XM_006235007 ⟹ XP_006235069

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	122,992,798 - 123,084,585 (+)	NCBI
Rnor_5.0	3	129,475,237 - 129,582,992 (+)	NCBI

Sequence:

show sequence

ACTGAGCTAAATCCCCAGCCTCATTTCTGTGCTTATGAATAAGAAAATGATACTTTGTGGGAGT
GACACTGAGGTTATGTAAATTGCCTATTTAGTATCCATTGAGGGGTTGTGACGGAATCCACTAT
TGCTATGGTGGTAACCAGATGGTAAATTAAAAAACAAATTAGTCATTCTTCATTCATCTGACAT
TTCCTACAAGGAAAAGCTCTCACTTTGTCTTTTGAATTTGTAAAATTAGCCAACATGGTTTCCT
ATTTTATTCTATTCCTTTTTGAACTTACTTTGATGATCAGGTTGCCCCAGATTTAGCTGGTCCT
AACCCTTTCCAGCTTGTGTCCATTTGTTCATGCATTGGTTTTATTTATTTATTTATTGGCCTAA
CATGATTTTTTCATTTTCATCTTGTCCTGACTCAACCATTTCTTCAAGGAACTCTAGTTCTTTT
TAGAAAATATAGTTAGGCATCAAATCTGATATGTGCGTCTTGCAATTGAGATGTGATTGGTCTC
CCTTGTACCCTGAGCCCTGAACTACAGTTGTGTTGTTGTTTATTCTATAGCCTAGGTTGACTTA
AACTTGTAACAATCCTCCTGCCTCAGCCTCCAGGTCGGAGTCACCATACCTGACTATGAAATTG
TTTTAATTAAATTCCTGGGACCAAATTTATGGAGGTGACTGAGTAACAGCCCAGCTCAACACCA
TTAAAAGCTTGTTATTGCGTAGTTTTCCAGGATCTGGATGCACACCATGCGGCTGTGCAAGACC
AAGTAGGAAATCAGGAGGAAGGCGTGGAGCCAGAGACAGACGTCAGCATGGATTCCTGGTTCAT
TCTTATCCTGTTTGGCAGTGGTCTAATACACATTAGTGCCAACAACACTACTACAGTTTCACCT
TCTTTAGGAACTACAAGATTAATTAAAACATCAACAACAGAATCGGCTAAGGAAGAGAATAAAA
CTTCAAATTCAACCTCTTCAGTAATTTCTCTTTCTGTGACACCAACATTCAGCCCAAATCTAAC
TCTGGAACCCACCTATGTGACTACTGTTAATTCTTCACACTCTGACAATGGGACCAAGAGAGCA
GCCAGCACGGAATCTGGAGGCACTACCATTTCACCAAACGGAACATACGGAACATGGCTTACTG
ATAACCAGTTCACGGATGCCAGAACAGAACCCTGGGAGGGGAATTCCAGCACTGCAGCAACCAC
TCCAGAAACCTTCCCCCCTGCAGGTAATTCTGACTCAAAAGACAGGAGAGATGAGACACCAATC
ATTGCGGTGATGGTGGCCCTGTCCTCTCTGCTAGTAATTGTGTTTATTATTATAGTTCTGTACA
TGTTAAGGTTTAAGAAATACAAGCAAGCTGGGAGCCATTCCAATTCTTTCCGCCTGTCAAATGG
CCGCACAGAGGATGTGGAGCCCCAAAGTGTACCACTTCTGGCCAGGTCCCCGAGCACCAACAGG
AAGTTCCCACCACTGCCTGTGGACAAGCTGGAAGAGGAGATTAACCGGAGAATGGCTGATGACA
ATAAGCTCTTCAGAGAGGAATTCAACGCCCTCCCTGCCTGTCCAATCCAGGCCACCTGTGAGGC
TGCCTCCAAGGAAGAAAACAAGGAAAAAAACCGATATGTAAACATCCTGCCTTATGACCACTCC
AGAGTGCACCTGACGCCTGTGGAAGGGGTTCCAGATTCTGATTACATCAACGCCTCATTCATTA
ATGGCTACCAGGAAAAGAACAAATTCATTGCTGCACAAGGACCAAAAGAAGAAACGGTGAATGA
TTTCTGGAGAATGATATGGGAACAGAACACAGCCACCATTGTCATGGTGACCAACCTGAAGGAG
AGAAAGGAGTGTAAATGTGCCCAGTATTGGCCAGACCAAGGCTGCTGGACCTATGGGAATGTCC
GTGTGTCTGTCGAGGATGTGACTGTTCTGGTGGACTACACAGTACGGAAATTCTGCATCCAGCA
GGTGGGCGACGTCACCAACAGGAAGCCACAGCGCCTCATCACTCAGTTCCATTTCACCAGCTGG
CCAGACTTTGGGGTGCCTTTTACCCCAATTGGCATGCTCAAGTTCCTCAAGAAGGTGAAAGCCT
GTAACCCTCAGTATGCAGGGGCTATCGTGGTCCACTGCAGTGCAGGTGTAGGGCGCACTGGCAC
CTTTGTTGTCATCGATGCCATGCTGGACATGATGCATTCGGAGCGCAAAGTGGATGTATATGGG
TTTGTGAGCCGGATCCGGGCCCAGCGCTGCCAGATGGTCCAGACAGACATGCAGTACGTCTTCA
TATACCAGGCCCTTCTGGAGCATTATCTATATGGCGACACAGAGCTGGAAGTGACTTCCCTAGA
CACCCACCTGCAAAAAATTTATAACAAGATCCCAGGAACTAGCAACAATGGACTAGAGGAGGAA
TTTAAGAAATTAACTTCAATCAAAATCCAAAATGACAAGATGCGTACGGGAAACCTTCCAGCCA
ACATGAAGAAGAACCGAGTTTTACAGATCATTCCATATGAATTTAACAGAGTGATCATTCCAGT
CAAACGGGGCGAAGAGAACACAGACTATGTGAACGCATCCTTCATTGATGGCTACCGGCAGAAA
GATTCCTACATCGCCAGCCAGGGCCCTCTTCTCCACACAATTGAGGACTTCTGGCGAATGATCT
GGGAATGGAAGTCCTGCTCCATTGTAATGCTAACAGAACTGGAAGAAAGAGGCCAGGAGAAGTG
TGCCCAGTACTGGCCATCTGATGGCCTGGTGTCCTATGGAGACATCACAGTTGAGCTGAAGAAG
GAGGAGGAATGTGAGAGCTACACTGTCCGAGACCTCCTGGTCACCAACACCAGGGAGAACAAGA
GTCGGCAGATCCGGCAGTTCCACTTCCACGGCTGGCCTGAGGTGGGCATCCCCAGCGATGGGAA
GGGTATGATCAACATCATTGCAGCAGTGCAGAAGCAGCAGCAGCAGTCAGGGAACCATCCCATC
ACTGTGCACTGCAGTGCCGGGGCAGGACGGACAGGGACCTTTTGTGCCTTGAGCACAGTCCTGG
AGCGCGTGAAAGCAGAAGGAATTTTGGATGTCTTCCAAACTGTCAAGAGCCTGCGGCTGCAGAG
GCCACACATGGTCCAGACACTGGAACAGTATGAATTCTGCTACAAGGTGGTACAGGAGTACATC
GATGCCTTCTCAGATTATGCCAACTTCAAGTGACAGGGGACAAGGCCCACAGACAGGAGAATTG
CCTTTAATATTTTGTAATATTCTGTTTTGTTAATATACCCAAAATTGTATATATCTTATAACTG
TTTTAGAAATGGCACATAGGCTTCTATTACCTATTAGGTGGAGATTTTGTATGTAAATGTGTTA
GCACTATAGTCCTTTTCCAGTGTTTTATTGGGGAATTAAATAGTGTGATATTTGAGTTGATTTA
ATGAAGTCCTTAGCCTGGAAATTGGGCCAGATTA

hide sequence

RefSeq Acc Id:

XM_039104340 ⟹ XP_038960268

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	117,650,203 - 117,759,744 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_036895	(Get FASTA)	NCBI Sequence Viewer
	XP_006235068	(Get FASTA)	NCBI Sequence Viewer
	XP_038960268	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA41983	(Get FASTA)	NCBI Sequence Viewer
	AAB02230	(Get FASTA)	NCBI Sequence Viewer
	AAH81828	(Get FASTA)	NCBI Sequence Viewer
	Q03348	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_036895 ⟸ NM_012763
- Peptide Label:	precursor
- UniProtKB:	Q66HJ7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDSWFILILFGSGLIHISANNTTTVSPSLGTTRLIKTSTTESAKEENKTSNSTSSVISLSVTPT FSPNLTLEPTYVTTVNSSHSDNGTKRAASTESGGTTISPNGTYGTWLTDNQFTDARTEPWEGNS STAATTPETFPPADETPIIAVMVALSSLLVIVFIIIVLYMLRFKKYKQAGSHSNSFRLSNGRTE DVEPQSVPLLARSPSTNRKFPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASK EENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWR MIWEQNTATIVMVTNLKERKECKCAQYWPDQGCWTYGNVRVSVEDVTVLVDYTVRKFCIQQVGD VTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVV IDAMLDMMHSERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLDTHL QKIYNKIPGTSNNGLEEEFKKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRG EENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQY WPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMI NIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHM VQTLEQYEFCYKVVQEYIDAFSDYANFK hide sequence

RefSeq Acc Id:

XP_006235068 ⟸ XM_006235006

- Peptide Label:

isoform X1

- Sequence:

show sequence

MDSWFILILFGSGLIHISANNTTTVSPSLGTTRLIKTSTTESAKEENKTSNSTSSVISLSVTPT
FSPNLTLEPTYVTTVNSSHSDNGTKRAASTESGGTTISPNGTYGTWLTDNQFTDARTEPWEGNS
STAATTPETFPPAGNSDSKDRRDETPIIAVMVALSSLLVIVFIIIVLYMLRFKKYKQAGSHSNS
FRLSNGRTEDVEPQSVPLLARSPSTNRKFPPLPVDKLEEEINRRMADDNKLFREEFNALPACPI
QATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPK
EETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCWTYGNVRVSVEDVTVLVDYTVR
KFCIQQVGDVTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAG
VGRTGTFVVIDAMLDMMHSERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTEL
EVTSLDTHLQKIYNKIPGTSNNGLEEEFKKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFN
RVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEE
RGQEKCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVG
IPSDGKGMINIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVK
SLRLQRPHMVQTLEQYEFCYKVVQEYIDAFSDYANFK

hide sequence

RefSeq Acc Id:

XP_006235069 ⟸ XM_006235007

- Peptide Label:

isoform X1

- Sequence:

show sequence

MDSWFILILFGSGLIHISANNTTTVSPSLGTTRLIKTSTTESAKEENKTSNSTSSVISLSVTPT
FSPNLTLEPTYVTTVNSSHSDNGTKRAASTESGGTTISPNGTYGTWLTDNQFTDARTEPWEGNS
STAATTPETFPPAGNSDSKDRRDETPIIAVMVALSSLLVIVFIIIVLYMLRFKKYKQAGSHSNS
FRLSNGRTEDVEPQSVPLLARSPSTNRKFPPLPVDKLEEEINRRMADDNKLFREEFNALPACPI
QATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPK
EETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCWTYGNVRVSVEDVTVLVDYTVR
KFCIQQVGDVTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAG
VGRTGTFVVIDAMLDMMHSERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTEL
EVTSLDTHLQKIYNKIPGTSNNGLEEEFKKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFN
RVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEE
RGQEKCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVG
IPSDGKGMINIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVK
SLRLQRPHMVQTLEQYEFCYKVVQEYIDAFSDYANFK

hide sequence

RefSeq Acc Id:

ENSRNOP00000069583 ⟸ ENSRNOT00000080379

RefSeq Acc Id:

ENSRNOP00000052657 ⟸ ENSRNOT00000055801

RefSeq Acc Id:	XP_038960268 ⟸ XM_039104340
- Peptide Label:	isoform X1

Protein Domains

TYR_PHOSPHATASE_2 Tyrosine-protein phosphatase

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13692434

Promoter ID:

EPDNEW_R2958

Type:

multiple initiation site

Name:

Ptpra_1

Description:

protein tyrosine phosphatase, receptor type, A

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	122,976,086 - 122,976,146	EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

Visual

CSV

TAB

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

Visual

CSV

TAB

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

Visual

CSV

TAB

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

Visual

CSV

TAB

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

Visual

CSV

TAB

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

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CSV

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Damaging Variants

Assembly: Rnor_5.0

Chromosome	Start Pos	End Pos	Reference Nucleotide	Variant Nucleotide	Variant Type	Strain
3	129571241	129571242	T	C	snv	ACI/EurMcwi (MCW), ZFDM (KyushuU), GH/OmrMcwi (MCW), SBH/Ygl (MCW), FHH/EurMcwi (MCW), FHL/EurMcwi (MCW), SR/JrHsd (MCW), SDLEF7/Barth (UDEL), LE/OrlBarth (UDEL), Crl:SD (UDEL), IS/Kyo (KyushuU), BUF/MNa (KyushuU), NIG-III/Hok (KyushuU), F344/DuCrlCrlj (KyushuU), LE/Stm (KyushuU), HTX/Kyo (KyushuU), F344/NSlc (KyushuU), RCS/Kyo (KyushuU), IS-Tlk/Kyo (KyushuU), F344/Stm (KyushuU), HWY/Slc (KyushuU), F344/Jcl (KyushuU), BDIX/NemOda (KyushuU), DOB/Oda (KyushuU), BDIX.Cg-Tal/NemOda (KyushuU), KFRS3B/Kyo (KyushuU), ZF (KyushuU), COP/CrCrl (MCW & UW)

Assembly: Rnor_6.0

Chromosome	Start Pos	End Pos	Reference Nucleotide	Variant Nucleotide	Variant Type	Strain
3	123073113	123073114	T	C	snv	CDS, WKY/NHsd (RGD), Buf/N (MCW), F344/NRrrc (MCW), M520/N (MCW), MR/N (MCW), WKY/N (MCW), FHL/EurMcwi (RGD), ACI/EurMcwi (RGD), BBDP/Wor (RGD), F344/NCrl (RGD), FHH/EurMcwi (RGD), LE/Stm (RGD), LEW/Crl (RGD), LEW/NCrlBR (RGD), MNS/Gib (RGD), SBH/Ygl (RGD), SHR/NHsd (RGD), SHRSP/Gcrc (RGD), SR/JrHsd (RGD), WAG/Rij (RGD), WKY/NCrl (RGD), WKY/Gcrc (RGD), ACI/N (MCW)

Assembly: RGSC_v3.4

Chromosome	Start Pos	End Pos	Reference Nucleotide	Variant Nucleotide	Variant Type	Strain
3	118157700	118157701	G	A	snv	SS/JrHsdMcwi (MCW)
3	118158825	118158826	T	C	snv	DA/BklArbNsi (ICAHN), SHRSP/Gcrc (MDC), ACI/N (KNAW), BUF/N (KNAW), F344/NRrrc (KNAW), LE/Stm (KNAW), M520/N (KNAW), MR/N (KNAW), WKY/N (KNAW), SHR/OlaIpcv (KNAW), ACI/EurMcwi (MCW), FHH/EurMcwi (MCW), FHL/EurMcwi (MCW), SR/JrHsd (MCW), COP/CrCrl (MCW & UW), GH/OmrMcwi (MCW), ACI/EurMcwi (ICL), BBDP/WorN (ICL), F344/NCrl (ICL), LE/Stm (ICL), FHH/EurMcwi (ICL), FHL/EurMcwi (ICL), LEW/Crl (ICL), LEW/NCrl (ICL), MHS/Gib (ICL), MNS/Gib (ICL), SBH/Ygl (ICL), SHR/OlaIpcv (ICL), SHR/NHsd (ICL), SHRSP/Gcrc (ICL), SR/JrHsd (ICL), WAG/Rij (ICL), WKY/Gcrc (ICL), WKY/NHsd (ICL), WKY/NCrl (ICL), HCR/1Mco (UMich), LCR/1Mco (UMich), HCR/2Mco (UMich), LCR/2Mco (UMich), F344/NHsd (ICAHN), SHR/OlaIpcv (ICL), FHH/EurMcwi (MDC)

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:3450	AgrOrtholog
Ensembl Genes	ENSRNOG00000021223	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000052657	ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOP00000069583	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000055801	ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOT00000080379	UniProtKB/TrEMBL
Gene3D-CATH	3.90.190.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7107006	IMAGE-MGC_LOAD
InterPro	Prot-tyrosine_phosphatase-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTPase_domain	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Tyr_Pase_AS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Tyr_Pase_cat	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Tyr_Pase_rcpt_a/e-type	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Tyr_Pase_rcpt_alpha	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TYR_PHOSPHATASE_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:25167	UniProtKB/TrEMBL
MGC_CLONE	MGC:93561	IMAGE-MGC_LOAD
NCBI Gene	25167	ENTREZGENE
PANTHER	PTHR19134:SF433	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Y_phosphatase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Ptpra	PhenoGen
PIRSF	PTPR_alpha	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTPR_alpha_epsilon	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS	PRTYPHPHTASE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	TYR_PHOSPHATASE_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TYR_PHOSPHATASE_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TYR_PHOSPHATASE_PTP	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	PTPc	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTPc_motif	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF52799	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR	TC229590
Transposagen	Ptpra	Transposagen
UniProt	A0A0G2JVR0_RAT	UniProtKB/TrEMBL
	PTPRA_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
	Q66HJ7	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	F1M833	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2002-06-10	Ptpra	Protein tyrosine phosphatase, receptor type, A			Symbol and Name status set to approved	70586	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_domains	has two intracellular PTPase domains	633823
gene_regulation	expression is inhibited by treatment with Il6 or Il1	633823

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD

Imported Annotations - PID (archival)

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Imported Disease Annotations - CTD

Imported Annotations - PID (archival)