PTPRA (protein tyrosine phosphatase receptor type A) - Rat Genome Database

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Gene: PTPRA (protein tyrosine phosphatase receptor type A) Homo sapiens
Analyze
Symbol: PTPRA
Name: protein tyrosine phosphatase receptor type A
RGD ID: 736543
HGNC Page HGNC
Description: Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in integrin-mediated signaling pathway; protein dephosphorylation; and regulation of focal adhesion assembly. Predicted to act upstream of or within insulin receptor signaling pathway and protein phosphorylation. Located in extracellular exosome. Part of receptor complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: HEPTP; HLPR; HPTPA; HPTPalpha; Leukocyte common antigen-related peptide (protein tyrosine phosphate); LRP; protein tyrosine phosphatase, receptor type, alpha polypeptide; protein-tyrosine phosphatase alpha; PTPA; PTPase-alpha; PTPLCA-related phosphatase; PTPRL2; R-PTP-alpha; receptor-type tyrosine-protein phosphatase alpha; RPTPA; tyrosine phosphatase alpha
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl202,873,420 - 3,039,076 (+)EnsemblGRCh38hg38GRCh38
GRCh38202,864,184 - 3,038,669 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37202,844,830 - 3,019,315 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36202,792,841 - 2,967,315 (+)NCBINCBI36hg18NCBI36
Build 34202,851,852 - 2,967,314NCBI
Celera202,907,196 - 3,081,302 (+)NCBI
Cytogenetic Map20p13NCBI
HuRef202,793,748 - 2,965,653 (+)NCBIHuRef
CHM1_1202,844,843 - 3,014,144 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:1383828   PMID:1611910   PMID:1639427   PMID:2166945   PMID:2169617   PMID:2170109   PMID:2172030   PMID:2175890   PMID:7518772   PMID:7691597   PMID:8493579   PMID:8647855  
PMID:8670803   PMID:8980254   PMID:9183007   PMID:9261115   PMID:9263011   PMID:9357975   PMID:9535845   PMID:9822658   PMID:9878055   PMID:10562275   PMID:10698938   PMID:10748206  
PMID:10777529   PMID:10787408   PMID:10893241   PMID:11042685   PMID:11099722   PMID:11357934   PMID:11401727   PMID:11436129   PMID:11496365   PMID:11498265   PMID:11676480   PMID:11780052  
PMID:11796915   PMID:11923305   PMID:12376545   PMID:12468645   PMID:12477932   PMID:12582170   PMID:12592337   PMID:12626515   PMID:14555984   PMID:14592422   PMID:14702039   PMID:15489334  
PMID:15588985   PMID:15592455   PMID:15951569   PMID:15978577   PMID:16338072   PMID:17081983   PMID:17212655   PMID:18046458   PMID:18183590   PMID:18211905   PMID:18216165   PMID:18728972  
PMID:18768480   PMID:19299420   PMID:19380743   PMID:19497848   PMID:20208566   PMID:20458337   PMID:20472558   PMID:20562859   PMID:21094165   PMID:21622556   PMID:21725282   PMID:21831360  
PMID:21873635   PMID:21900206   PMID:22647903   PMID:22801373   PMID:23029023   PMID:23318421   PMID:23382219   PMID:23487342   PMID:23532252   PMID:24189400   PMID:24217252   PMID:24652832  
PMID:25277244   PMID:25393624   PMID:25631816   PMID:25694432   PMID:26186194   PMID:26496610   PMID:27432908   PMID:27609421   PMID:27880917   PMID:27935824   PMID:28065597   PMID:28298427  
PMID:28330616   PMID:28514442   PMID:28656243   PMID:28675297   PMID:29507755   PMID:30021884   PMID:30594456   PMID:30631154   PMID:30639242   PMID:30745168   PMID:31160270   PMID:31545274  
PMID:31560641   PMID:31924785   PMID:31980649   PMID:32062451   PMID:32139509   PMID:32460013   PMID:32694731   PMID:33566639   PMID:33845483   PMID:33853613   PMID:33961781   PMID:34709727  


Genomics

Comparative Map Data
PTPRA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl202,873,420 - 3,039,076 (+)EnsemblGRCh38hg38GRCh38
GRCh38202,864,184 - 3,038,669 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37202,844,830 - 3,019,315 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36202,792,841 - 2,967,315 (+)NCBINCBI36hg18NCBI36
Build 34202,851,852 - 2,967,314NCBI
Celera202,907,196 - 3,081,302 (+)NCBI
Cytogenetic Map20p13NCBI
HuRef202,793,748 - 2,965,653 (+)NCBIHuRef
CHM1_1202,844,843 - 3,014,144 (+)NCBICHM1_1
Ptpra
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392130,292,198 - 130,396,220 (+)NCBIGRCm39mm39
GRCm39 Ensembl2130,292,198 - 130,398,044 (+)Ensembl
GRCm382130,450,278 - 130,554,300 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2130,450,278 - 130,556,124 (+)EnsemblGRCm38mm10GRCm38
MGSCv372130,276,014 - 130,380,036 (+)NCBIGRCm37mm9NCBIm37
MGSCv362130,194,915 - 130,245,464 (+)NCBImm8
Celera2131,674,730 - 131,778,720 (+)NCBICelera
Cytogenetic Map2F1NCBI
cM Map263.23NCBI
Ptpra
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23117,650,146 - 117,759,744 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl3117,650,183 - 117,759,728 (+)Ensembl
Rnor_6.03122,976,066 - 123,084,585 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3122,976,104 - 123,084,863 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03129,475,237 - 129,582,992 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43118,061,713 - 118,171,300 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13118,022,615 - 118,077,164 (+)NCBI
Celera3116,464,194 - 116,570,590 (+)NCBICelera
Cytogenetic Map3q36NCBI
Ptpra
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541513,819,717 - 13,967,068 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541513,819,934 - 13,967,068 (+)NCBIChiLan1.0ChiLan1.0
PTPRA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1202,726,657 - 2,888,195 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl202,801,905 - 2,888,195 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0202,962,701 - 3,125,282 (+)NCBIMhudiblu_PPA_v0panPan3
PTPRA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12418,224,355 - 18,395,650 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2418,224,801 - 18,296,350 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2418,052,684 - 18,223,899 (-)NCBI
ROS_Cfam_1.02418,643,403 - 18,815,534 (-)NCBI
ROS_Cfam_1.0 Ensembl2418,643,403 - 18,815,666 (-)Ensembl
UMICH_Zoey_3.12418,236,577 - 18,408,752 (-)NCBI
UNSW_CanFamBas_1.02418,349,051 - 18,519,508 (-)NCBI
UU_Cfam_GSD_1.02418,677,051 - 18,848,067 (-)NCBI
Ptpra
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640167,313,690 - 167,441,022 (-)NCBI
SpeTri2.0NW_00493648515,745,054 - 15,872,377 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTPRA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1732,633,612 - 32,797,104 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11732,638,494 - 32,797,110 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21737,008,987 - 37,167,722 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PTPRA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1233,559,634 - 33,724,446 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl233,559,697 - 33,722,137 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607110,789,232 - 10,956,158 (-)NCBIVero_WHO_p1.0
Ptpra
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247413,997,853 - 4,155,130 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
WI-16594  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37202,964,068 - 2,964,192UniSTSGRCh37
Build 36202,912,068 - 2,912,192RGDNCBI36
Celera203,026,034 - 3,026,158RGD
Cytogenetic Map20p13UniSTS
HuRef202,910,022 - 2,910,146UniSTS
GeneMap99-GB4 RH Map2013.45UniSTS
Whitehead-RH Map2024.9UniSTS
D20S731  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37203,018,996 - 3,019,113UniSTSGRCh37
Build 36202,966,996 - 2,967,113RGDNCBI36
Celera203,080,983 - 3,081,100RGD
Cytogenetic Map20p13UniSTS
HuRef202,965,334 - 2,965,451UniSTS
GeneMap99-GB4 RH Map2011.46UniSTS
Whitehead-RH Map205.1UniSTS
Whitehead-YAC Contig Map20 UniSTS
NCBI RH Map2059.4UniSTS
WI-9015  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37203,018,996 - 3,019,119UniSTSGRCh37
Build 36202,966,996 - 2,967,119RGDNCBI36
Celera203,080,983 - 3,081,106RGD
Cytogenetic Map20p13UniSTS
HuRef202,965,334 - 2,965,457UniSTS
GeneMap99-GB4 RH Map2011.46UniSTS
Whitehead-RH Map2024.8UniSTS
Whitehead-YAC Contig Map20 UniSTS
NCBI RH Map2060.5UniSTS
SHGC-145577  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37202,845,116 - 2,845,389UniSTSGRCh37
Build 36202,793,116 - 2,793,389RGDNCBI36
Celera202,907,471 - 2,907,744RGD
Cytogenetic Map20p13UniSTS
HuRef202,794,023 - 2,794,296UniSTS
TNG Radiation Hybrid Map201768.0UniSTS
G65674  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37202,962,407 - 2,962,602UniSTSGRCh37
Build 36202,910,407 - 2,910,602RGDNCBI36
Celera203,024,373 - 3,024,568RGD
Cytogenetic Map12q13.1UniSTS
Cytogenetic Map20p13UniSTS
PMC310823P9  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37202,930,483 - 2,930,582UniSTSGRCh37
Build 36202,878,483 - 2,878,582RGDNCBI36
Celera202,992,454 - 2,992,553RGD
Cytogenetic Map20p13UniSTS
HuRef202,879,345 - 2,879,444UniSTS
PTPRA_1754  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37203,018,704 - 3,019,413UniSTSGRCh37
Build 36202,966,704 - 2,967,413RGDNCBI36
Celera203,080,691 - 3,081,400RGD
HuRef202,965,042 - 2,965,751UniSTS
AB046072  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37203,018,065 - 3,018,191UniSTSGRCh37
Build 36202,966,065 - 2,966,191RGDNCBI36
Celera203,080,052 - 3,080,178RGD
HuRef202,964,403 - 2,964,529UniSTS
STS-M34668  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37203,019,009 - 3,019,266UniSTSGRCh37
Build 36202,967,009 - 2,967,266RGDNCBI36
Celera203,080,996 - 3,081,253RGD
Cytogenetic Map20p13UniSTS
HuRef202,965,347 - 2,965,604UniSTS
GeneMap99-GB4 RH Map2013.45UniSTS
SHGC-30809  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37202,847,177 - 2,847,323UniSTSGRCh37
Build 36202,795,177 - 2,795,323RGDNCBI36
Celera202,909,532 - 2,909,678RGD
Cytogenetic Map20p13UniSTS
HuRef202,796,084 - 2,796,230UniSTS
Stanford-G3 RH Map20129.0UniSTS
NCBI RH Map2021.9UniSTS
GeneMap99-G3 RH Map20129.0UniSTS
G29236  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37202,887,738 - 2,887,880UniSTSGRCh37
Build 36202,835,738 - 2,835,880RGDNCBI36
Celera202,949,717 - 2,949,859RGD
Cytogenetic Map20p13UniSTS
HuRef202,836,592 - 2,836,734UniSTS
RH66062  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37202,843,980 - 2,844,690UniSTSGRCh37
Celera202,906,331 - 2,907,045UniSTS
Cytogenetic Map20p13UniSTS
HuRef202,792,883 - 2,793,597UniSTS
GeneMap99-GB4 RH Map2011.93UniSTS
NCBI RH Map2061.5UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2008
Count of miRNA genes:567
Interacting mature miRNAs:638
Transcripts:ENST00000216877, ENST00000318266, ENST00000356147, ENST00000358719, ENST00000380393, ENST00000399903, ENST00000425918, ENST00000430705, ENST00000431048, ENST00000455631
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 2438 2602 1570 470 1820 311 3890 1489 3733 417 1460 1613 175 1 1204 2321 6 2
Low 1 389 156 154 131 154 467 708 1 2 467
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001385302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001385303 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001385304 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001385305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001385306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001385307 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001385308 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001385310 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001385311 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001385312 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001385313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001385314 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001385315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001385316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001385317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001385318 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001385319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001385320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001385321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001388320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001388321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001388322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001388323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001388324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_002836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_080840 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_080841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_170936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB209702 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI284972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK090743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK290233 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK294499 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK294990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK297293 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK297647 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL121905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL161656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC027308 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BI597187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ213974 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX571753 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KX533496 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M34668 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X53364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X54130 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X54890 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000216877   ⟹   ENSP00000216877
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl202,873,489 - 3,039,076 (+)Ensembl
RefSeq Acc Id: ENST00000318266   ⟹   ENSP00000314568
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl202,873,683 - 3,038,674 (+)Ensembl
RefSeq Acc Id: ENST00000356147   ⟹   ENSP00000348468
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl202,923,207 - 3,038,668 (+)Ensembl
RefSeq Acc Id: ENST00000380393   ⟹   ENSP00000369756
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl202,864,184 - 3,038,674 (+)Ensembl
RefSeq Acc Id: ENST00000399903   ⟹   ENSP00000382787
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl202,873,481 - 3,038,669 (+)Ensembl
RefSeq Acc Id: ENST00000430705   ⟹   ENSP00000394132
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl202,873,683 - 2,986,849 (+)Ensembl
RefSeq Acc Id: ENST00000431048   ⟹   ENSP00000390775
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl202,873,518 - 2,965,202 (+)Ensembl
RefSeq Acc Id: ENST00000455631   ⟹   ENSP00000414089
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl202,873,420 - 3,005,104 (+)Ensembl
RefSeq Acc Id: NM_001385302   ⟹   NP_001372231
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38202,873,481 - 3,038,669 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001385303   ⟹   NP_001372232
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38202,873,481 - 3,038,669 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001385304   ⟹   NP_001372233
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38202,873,481 - 3,038,669 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001385305   ⟹   NP_001372234
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38202,873,481 - 3,038,669 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001385306   ⟹   NP_001372235
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38202,873,481 - 3,038,669 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001385307   ⟹   NP_001372236
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38202,873,481 - 3,038,669 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001385308   ⟹   NP_001372237
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38202,873,481 - 3,038,669 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001385310   ⟹   NP_001372239
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38202,873,481 - 3,038,669 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001385311   ⟹   NP_001372240
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38202,873,481 - 3,038,669 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001385312   ⟹   NP_001372241
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38202,873,481 - 3,038,669 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001385313   ⟹   NP_001372242
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38202,873,481 - 3,038,669 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001385314   ⟹   NP_001372243
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38202,873,481 - 3,038,669 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001385315   ⟹   NP_001372244
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38202,873,481 - 3,038,669 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001385316   ⟹   NP_001372245
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38202,873,481 - 3,038,669 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001385317   ⟹   NP_001372246
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38202,873,481 - 3,038,669 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001385318   ⟹   NP_001372247
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38202,873,481 - 3,038,669 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001385319   ⟹   NP_001372248
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38202,873,481 - 3,038,669 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001385320   ⟹   NP_001372249
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38202,873,481 - 3,038,669 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001385321   ⟹   NP_001372250
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38202,873,481 - 3,038,669 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001388320   ⟹   NP_001375249
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38202,873,481 - 3,038,669 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001388321   ⟹   NP_001375250
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38202,873,481 - 3,038,669 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001388322   ⟹   NP_001375251
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38202,873,481 - 3,038,669 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001388323   ⟹   NP_001375252
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38202,873,481 - 3,038,669 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001388324   ⟹   NP_001375253
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38202,873,481 - 3,038,669 (+)NCBI
Sequence:
RefSeq Acc Id: NM_002836   ⟹   NP_002827
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38202,864,184 - 3,038,669 (+)NCBI
GRCh37202,844,841 - 3,019,316 (+)NCBI
Build 36202,792,841 - 2,967,315 (+)NCBI Archive
HuRef202,793,748 - 2,965,653 (+)ENTREZGENE
CHM1_1202,844,843 - 3,014,144 (+)NCBI
Sequence:
RefSeq Acc Id: NM_080840   ⟹   NP_543030
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38202,873,481 - 3,038,669 (+)NCBI
GRCh37202,844,841 - 3,019,316 (+)NCBI
Build 36202,802,142 - 2,967,315 (+)NCBI Archive
HuRef202,793,748 - 2,965,653 (+)ENTREZGENE
CHM1_1202,854,144 - 3,014,144 (+)NCBI
Sequence:
RefSeq Acc Id: NM_080841   ⟹   NP_543031
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38202,873,481 - 3,038,669 (+)NCBI
GRCh37202,844,841 - 3,019,316 (+)NCBI
Build 36202,851,853 - 2,967,315 (+)NCBI Archive
HuRef202,793,748 - 2,965,653 (+)ENTREZGENE
CHM1_1202,903,870 - 3,014,144 (+)NCBI
Sequence:
RefSeq Acc Id: NR_170936
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38202,873,481 - 3,038,669 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001372231 (Get FASTA)   NCBI Sequence Viewer  
  NP_001372232 (Get FASTA)   NCBI Sequence Viewer  
  NP_001372233 (Get FASTA)   NCBI Sequence Viewer  
  NP_001372234 (Get FASTA)   NCBI Sequence Viewer  
  NP_001372235 (Get FASTA)   NCBI Sequence Viewer  
  NP_001372236 (Get FASTA)   NCBI Sequence Viewer  
  NP_001372237 (Get FASTA)   NCBI Sequence Viewer  
  NP_001372239 (Get FASTA)   NCBI Sequence Viewer  
  NP_001372240 (Get FASTA)   NCBI Sequence Viewer  
  NP_001372241 (Get FASTA)   NCBI Sequence Viewer  
  NP_001372242 (Get FASTA)   NCBI Sequence Viewer  
  NP_001372243 (Get FASTA)   NCBI Sequence Viewer  
  NP_001372244 (Get FASTA)   NCBI Sequence Viewer  
  NP_001372245 (Get FASTA)   NCBI Sequence Viewer  
  NP_001372246 (Get FASTA)   NCBI Sequence Viewer  
  NP_001372247 (Get FASTA)   NCBI Sequence Viewer  
  NP_001372248 (Get FASTA)   NCBI Sequence Viewer  
  NP_001372249 (Get FASTA)   NCBI Sequence Viewer  
  NP_001372250 (Get FASTA)   NCBI Sequence Viewer  
  NP_001375249 (Get FASTA)   NCBI Sequence Viewer  
  NP_001375250 (Get FASTA)   NCBI Sequence Viewer  
  NP_001375251 (Get FASTA)   NCBI Sequence Viewer  
  NP_001375252 (Get FASTA)   NCBI Sequence Viewer  
  NP_001375253 (Get FASTA)   NCBI Sequence Viewer  
  NP_002827 (Get FASTA)   NCBI Sequence Viewer  
  NP_543030 (Get FASTA)   NCBI Sequence Viewer  
  NP_543031 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA36528 (Get FASTA)   NCBI Sequence Viewer  
  AAH27308 (Get FASTA)   NCBI Sequence Viewer  
  AQN67649 (Get FASTA)   NCBI Sequence Viewer  
  BAD92939 (Get FASTA)   NCBI Sequence Viewer  
  BAF82922 (Get FASTA)   NCBI Sequence Viewer  
  BAH11790 (Get FASTA)   NCBI Sequence Viewer  
  BAH11942 (Get FASTA)   NCBI Sequence Viewer  
  BAH12540 (Get FASTA)   NCBI Sequence Viewer  
  BAH12641 (Get FASTA)   NCBI Sequence Viewer  
  CAA37447 (Get FASTA)   NCBI Sequence Viewer  
  CAA38065 (Get FASTA)   NCBI Sequence Viewer  
  CAA38662 (Get FASTA)   NCBI Sequence Viewer  
  CAE11878 (Get FASTA)   NCBI Sequence Viewer  
  EAX10561 (Get FASTA)   NCBI Sequence Viewer  
  EAX10562 (Get FASTA)   NCBI Sequence Viewer  
  EAX10563 (Get FASTA)   NCBI Sequence Viewer  
  P18433 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_002827   ⟸   NM_002836
- Peptide Label: isoform 1 precursor
- UniProtKB: P18433 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_543030   ⟸   NM_080840
- Peptide Label: isoform 2 precursor
- UniProtKB: P18433 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_543031   ⟸   NM_080841
- Peptide Label: isoform 2 precursor
- UniProtKB: P18433 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000382787   ⟸   ENST00000399903
RefSeq Acc Id: ENSP00000216877   ⟸   ENST00000216877
RefSeq Acc Id: ENSP00000414089   ⟸   ENST00000455631
RefSeq Acc Id: ENSP00000394132   ⟸   ENST00000430705
RefSeq Acc Id: ENSP00000390775   ⟸   ENST00000431048
RefSeq Acc Id: ENSP00000369756   ⟸   ENST00000380393
RefSeq Acc Id: ENSP00000348468   ⟸   ENST00000356147
RefSeq Acc Id: ENSP00000314568   ⟸   ENST00000318266
RefSeq Acc Id: NP_001372235   ⟸   NM_001385306
- Peptide Label: isoform 1 precursor
RefSeq Acc Id: NP_001372249   ⟸   NM_001385320
- Peptide Label: isoform 13 precursor
RefSeq Acc Id: NP_001372231   ⟸   NM_001385302
- Peptide Label: isoform 3 precursor
RefSeq Acc Id: NP_001372234   ⟸   NM_001385305
- Peptide Label: isoform 1 precursor
RefSeq Acc Id: NP_001372243   ⟸   NM_001385314
- Peptide Label: isoform 8 precursor
RefSeq Acc Id: NP_001372248   ⟸   NM_001385319
- Peptide Label: isoform 13 precursor
RefSeq Acc Id: NP_001372241   ⟸   NM_001385312
- Peptide Label: isoform 6 precursor
RefSeq Acc Id: NP_001372244   ⟸   NM_001385315
- Peptide Label: isoform 9 precursor
RefSeq Acc Id: NP_001372250   ⟸   NM_001385321
- Peptide Label: isoform 14 precursor
RefSeq Acc Id: NP_001372246   ⟸   NM_001385317
- Peptide Label: isoform 11 precursor
RefSeq Acc Id: NP_001372245   ⟸   NM_001385316
- Peptide Label: isoform 10
RefSeq Acc Id: NP_001372232   ⟸   NM_001385303
- Peptide Label: isoform 3 precursor
RefSeq Acc Id: NP_001372233   ⟸   NM_001385304
- Peptide Label: isoform 4 precursor
RefSeq Acc Id: NP_001372239   ⟸   NM_001385310
- Peptide Label: isoform 5 precursor
RefSeq Acc Id: NP_001372242   ⟸   NM_001385313
- Peptide Label: isoform 7 precursor
RefSeq Acc Id: NP_001372247   ⟸   NM_001385318
- Peptide Label: isoform 12 precursor
RefSeq Acc Id: NP_001372236   ⟸   NM_001385307
- Peptide Label: isoform 1 precursor
RefSeq Acc Id: NP_001372237   ⟸   NM_001385308
- Peptide Label: isoform 1 precursor
RefSeq Acc Id: NP_001372240   ⟸   NM_001385311
- Peptide Label: isoform 2 precursor
RefSeq Acc Id: NP_001375253   ⟸   NM_001388324
- Peptide Label: isoform 15
RefSeq Acc Id: NP_001375252   ⟸   NM_001388323
- Peptide Label: isoform 15
RefSeq Acc Id: NP_001375251   ⟸   NM_001388322
- Peptide Label: isoform 15
RefSeq Acc Id: NP_001375250   ⟸   NM_001388321
- Peptide Label: isoform 2 precursor
RefSeq Acc Id: NP_001375249   ⟸   NM_001388320
- Peptide Label: isoform 1 precursor
Promoters
RGD ID:6798925
Promoter ID:HG_KWN:38398
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000318266,   ENST00000358719,   ENST00000399903,   OTTHUMT00000077682,   OTTHUMT00000077685,   OTTHUMT00000077686,   OTTHUMT00000077688,   OTTHUMT00000077689,   UC002WHL.1,   UC002WHM.1
Position:
Human AssemblyChrPosition (strand)Source
Build 36202,801,376 - 2,802,102 (+)MPROMDB
RGD ID:13206191
Promoter ID:EPDNEW_H26676
Type:initiation region
Name:PTPRA_4
Description:protein tyrosine phosphatase, receptor type A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H26677  EPDNEW_H26680  EPDNEW_H26679  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38202,864,009 - 2,864,069EPDNEW
RGD ID:13206193
Promoter ID:EPDNEW_H26677
Type:initiation region
Name:PTPRA_2
Description:protein tyrosine phosphatase, receptor type A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H26676  EPDNEW_H26680  EPDNEW_H26679  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38202,864,207 - 2,864,267EPDNEW
RGD ID:13206199
Promoter ID:EPDNEW_H26679
Type:initiation region
Name:PTPRA_1
Description:protein tyrosine phosphatase, receptor type A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H26676  EPDNEW_H26677  EPDNEW_H26680  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38202,873,518 - 2,873,578EPDNEW
RGD ID:13206197
Promoter ID:EPDNEW_H26680
Type:single initiation site
Name:PTPRA_3
Description:protein tyrosine phosphatase, receptor type A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H26676  EPDNEW_H26677  EPDNEW_H26679  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38202,884,794 - 2,884,854EPDNEW
RGD ID:6798924
Promoter ID:HG_KWN:38400
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   Lymphoblastoid
Transcripts:UC002WHO.1
Position:
Human AssemblyChrPosition (strand)Source
Build 36202,914,979 - 2,915,479 (+)MPROMDB

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 20p13-11.21(chr20:89939-25697564)x3 copy number gain See cases [RCV000051227] Chr20:89939..25697564 [GRCh38]
Chr20:70580..25678200 [GRCh37]
Chr20:18580..25626200 [NCBI36]
Chr20:20p13-11.21
pathogenic
GRCh38/hg38 20p13-11.23(chr20:89939-19146279)x3 copy number gain See cases [RCV000051041] Chr20:89939..19146279 [GRCh38]
Chr20:70580..19126923 [GRCh37]
Chr20:18580..19074923 [NCBI36]
Chr20:20p13-11.23
pathogenic
GRCh38/hg38 20p13(chr20:2595077-3004837)x3 copy number gain See cases [RCV000052758] Chr20:2595077..3004837 [GRCh38]
Chr20:2575723..2985483 [GRCh37]
Chr20:2523723..2933483 [NCBI36]
Chr20:20p13
uncertain significance
GRCh38/hg38 20p13(chr20:2911664-4017687)x3 copy number gain See cases [RCV000052759] Chr20:2911664..4017687 [GRCh38]
Chr20:2892310..3998334 [GRCh37]
Chr20:2840310..3946334 [NCBI36]
Chr20:20p13
uncertain significance
GRCh38/hg38 20p13-11.23(chr20:89939-19071495)x3 copy number gain See cases [RCV000052995] Chr20:89939..19071495 [GRCh38]
Chr20:70580..19052139 [GRCh37]
Chr20:18580..19000139 [NCBI36]
Chr20:20p13-11.23
pathogenic
GRCh38/hg38 20p13-11.22(chr20:89939-21787252)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052996]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052996]|See cases [RCV000052996] Chr20:89939..21787252 [GRCh38]
Chr20:70580..21767890 [GRCh37]
Chr20:18580..21715890 [NCBI36]
Chr20:20p13-11.22
pathogenic
GRCh38/hg38 20p13-12.1(chr20:89939-14818511)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052997]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052997]|See cases [RCV000052997] Chr20:89939..14818511 [GRCh38]
Chr20:70580..14799157 [GRCh37]
Chr20:18580..14747157 [NCBI36]
Chr20:20p13-12.1
pathogenic
NM_022575.3(VPS16):c.1023C>T (p.Ala341=) single nucleotide variant Malignant melanoma [RCV000063707] Chr20:2862082 [GRCh38]
Chr20:2842728 [GRCh37]
Chr20:2790728 [NCBI36]
Chr20:20p13
not provided
NM_002836.3(PTPRA):c.-129+11680G>C single nucleotide variant Lung cancer [RCV000101528] Chr20:2876997 [GRCh38]
Chr20:2857643 [GRCh37]
Chr20:20p13
uncertain significance
GRCh38/hg38 20p13-q11.1(chr20:80106-30227427)x3 copy number gain See cases [RCV000133996] Chr20:80106..30227427 [GRCh38]
Chr20:60747..29462103 [GRCh37]
Chr20:8747..28075764 [NCBI36]
Chr20:20p13-q11.1
pathogenic
GRCh38/hg38 20p13-q13.33(chr20:99557-64277321)x3 copy number gain See cases [RCV000135859] Chr20:99557..64277321 [GRCh38]
Chr20:80198..62908674 [GRCh37]
Chr20:28198..62379118 [NCBI36]
Chr20:20p13-q13.33
pathogenic
GRCh38/hg38 20p13-12.1(chr20:80106-13029401)x3 copy number gain See cases [RCV000138677] Chr20:80106..13029401 [GRCh38]
Chr20:60747..13010049 [GRCh37]
Chr20:8747..12958049 [NCBI36]
Chr20:20p13-12.1
pathogenic
GRCh38/hg38 20p13-12.3(chr20:80093-6386012)x3 copy number gain See cases [RCV000139597] Chr20:80093..6386012 [GRCh38]
Chr20:60734..6366659 [GRCh37]
Chr20:8734..6314659 [NCBI36]
Chr20:20p13-12.3
pathogenic
GRCh38/hg38 20p13-12.3(chr20:84402-6159078)x3 copy number gain See cases [RCV000141348] Chr20:84402..6159078 [GRCh38]
Chr20:65043..6139725 [GRCh37]
Chr20:13043..6087725 [NCBI36]
Chr20:20p13-12.3
pathogenic
GRCh38/hg38 20p13-11.1(chr20:80927-26324843)x3 copy number gain See cases [RCV000142017] Chr20:80927..26324843 [GRCh38]
Chr20:61568..26305479 [GRCh37]
Chr20:9568..26253479 [NCBI36]
Chr20:20p13-11.1
pathogenic
GRCh38/hg38 20p13-12.3(chr20:80927-5447679)x3 copy number gain See cases [RCV000142285] Chr20:80927..5447679 [GRCh38]
Chr20:61568..5428325 [GRCh37]
Chr20:9568..5376325 [NCBI36]
Chr20:20p13-12.3
uncertain significance
GRCh38/hg38 20p13-12.3(chr20:1269303-8626911)x3 copy number gain See cases [RCV000142917] Chr20:1269303..8626911 [GRCh38]
Chr20:1249947..8607558 [GRCh37]
Chr20:1197947..8555558 [NCBI36]
Chr20:20p13-12.3
pathogenic
GRCh38/hg38 20p13-11.23(chr20:80928-18688031)x3 copy number gain See cases [RCV000143426] Chr20:80928..18688031 [GRCh38]
Chr20:61569..18668675 [GRCh37]
Chr20:9569..18616675 [NCBI36]
Chr20:20p13-11.23
pathogenic
GRCh38/hg38 20p13(chr20:2526755-3081651)x3 copy number gain See cases [RCV000143472] Chr20:2526755..3081651 [GRCh38]
Chr20:2507401..3062297 [GRCh37]
Chr20:2455401..3010297 [NCBI36]
Chr20:20p13
uncertain significance
GRCh37/hg19 20p13-12.3(chr20:121521-5564937)x3 copy number gain See cases [RCV000239772] Chr20:121521..5564937 [GRCh37]
Chr20:20p13-12.3
pathogenic
GRCh37/hg19 20p13-11.1(chr20:80198-26075841)x3 copy number gain See cases [RCV000239954] Chr20:80198..26075841 [GRCh37]
Chr20:20p13-11.1
pathogenic
GRCh37/hg19 20p13(chr20:61568-4914872)x3 copy number gain See cases [RCV000446883] Chr20:61568..4914872 [GRCh37]
Chr20:20p13
pathogenic
GRCh37/hg19 20p13(chr20:61568-4904599)x3 copy number gain See cases [RCV000448397] Chr20:61568..4904599 [GRCh37]
Chr20:20p13
pathogenic
GRCh37/hg19 20p13-q11.21(chr20:80198-26208081)x3 copy number gain not provided [RCV000487461] Chr20:80198..26208081 [GRCh37]
Chr20:20p13-q11.21
pathogenic
GRCh37/hg19 20p13-12.3(chr20:213423-5483406)x3 copy number gain See cases [RCV000510531] Chr20:213423..5483406 [GRCh37]
Chr20:20p13-12.3
uncertain significance
GRCh37/hg19 20p13-12.3(chr20:2463101-8185680)x1 copy number loss See cases [RCV000511897] Chr20:2463101..8185680 [GRCh37]
Chr20:20p13-12.3
pathogenic
GRCh37/hg19 20p13(chr20:2802218-4019837)x1 copy number loss See cases [RCV000511017] Chr20:2802218..4019837 [GRCh37]
Chr20:20p13
uncertain significance
GRCh37/hg19 20p13-q13.33(chr20:61569-62915555)x3 copy number gain See cases [RCV000510832] Chr20:61569..62915555 [GRCh37]
Chr20:20p13-q13.33
pathogenic
GRCh37/hg19 20p13-q13.33(chr20:61569-62915555) copy number gain See cases [RCV000512450] Chr20:61569..62915555 [GRCh37]
Chr20:20p13-q13.33
pathogenic
GRCh37/hg19 20p13-12.2(chr20:61568-10486106)x3 copy number gain See cases [RCV000512556] Chr20:61568..10486106 [GRCh37]
Chr20:20p13-12.2
likely pathogenic
GRCh37/hg19 20p13(chr20:2802218-2970332)x1 copy number loss not provided [RCV000684104] Chr20:2802218..2970332 [GRCh37]
Chr20:20p13
uncertain significance
GRCh37/hg19 20p13-q13.33(chr20:63244-62948788)x3 copy number gain not provided [RCV000741058] Chr20:63244..62948788 [GRCh37]
Chr20:20p13-q13.33
pathogenic
GRCh37/hg19 20p13-q13.33(chr20:63244-62961294)x3 copy number gain not provided [RCV000741059] Chr20:63244..62961294 [GRCh37]
Chr20:20p13-q13.33
pathogenic
GRCh37/hg19 20p13(chr20:2739583-3064949)x3 copy number gain not provided [RCV000741074] Chr20:2739583..3064949 [GRCh37]
Chr20:20p13
benign
GRCh37/hg19 20p13-q13.33(chr20:63244-62912463)x3 copy number gain not provided [RCV000741057] Chr20:63244..62912463 [GRCh37]
Chr20:20p13-q13.33
pathogenic
NM_022575.4(VPS16):c.1939C>T (p.Arg647Ter) single nucleotide variant not provided [RCV001543524] Chr20:2864990 [GRCh38]
Chr20:2845636 [GRCh37]
Chr20:20p13
pathogenic
GRCh37/hg19 20p13(chr20:2806498-4007381)x1 copy number loss not provided [RCV001007072] Chr20:2806498..4007381 [GRCh37]
Chr20:20p13
uncertain significance
NM_001385305.1(PTPRA):c.462G>A (p.Ala154=) single nucleotide variant not provided [RCV000971436] Chr20:2986784 [GRCh38]
Chr20:2967430 [GRCh37]
Chr20:20p13
benign
GRCh37/hg19 20p13(chr20:2852007-3084597)x3 copy number gain not provided [RCV001007073] Chr20:2852007..3084597 [GRCh37]
Chr20:20p13
uncertain significance
GRCh37/hg19 20p13(chr20:2738670-3054217)x3 copy number gain not provided [RCV000846074] Chr20:2738670..3054217 [GRCh37]
Chr20:20p13
uncertain significance
GRCh37/hg19 20p13(chr20:2851899-3110055)x3 copy number gain not provided [RCV000846901] Chr20:2851899..3110055 [GRCh37]
Chr20:20p13
uncertain significance
NM_022575.4(VPS16):c.2271+148G>A single nucleotide variant not provided [RCV001614019] Chr20:2865643 [GRCh38]
Chr20:2846289 [GRCh37]
Chr20:20p13
benign
NM_022575.4(VPS16):c.1818+22G>A single nucleotide variant not provided [RCV001596309] Chr20:2864484 [GRCh38]
Chr20:2845130 [GRCh37]
Chr20:20p13
benign
GRCh37/hg19 20p13-11.1(chr20:61568-26305479)x3 copy number gain not provided [RCV001007068] Chr20:61568..26305479 [GRCh37]
Chr20:20p13-11.1
pathogenic
NM_022575.4(VPS16):c.1698C>T (p.Ile566=) single nucleotide variant not provided [RCV001537470] Chr20:2864265 [GRCh38]
Chr20:2844911 [GRCh37]
Chr20:20p13
benign
GRCh37/hg19 20p13(chr20:2802218-4010802)x3 copy number gain not provided [RCV001258752] Chr20:2802218..4010802 [GRCh37]
Chr20:20p13
uncertain significance
NM_022575.4(VPS16):c.1903C>T (p.Arg635Ter) single nucleotide variant not provided [RCV001268874] Chr20:2864631 [GRCh38]
Chr20:2845277 [GRCh37]
Chr20:20p13
pathogenic|conflicting interpretations of pathogenicity
NM_022575.4(VPS16):c.1749C>T (p.Asn583=) single nucleotide variant not provided [RCV001682410] Chr20:2864393 [GRCh38]
Chr20:2845039 [GRCh37]
Chr20:20p13
benign

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:9664 AgrOrtholog
COSMIC PTPRA COSMIC
Ensembl Genes ENSG00000132670 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000216877 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000314568 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000348468 UniProtKB/Swiss-Prot
  ENSP00000382787 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000390775 UniProtKB/TrEMBL
  ENSP00000394132 UniProtKB/TrEMBL
  ENSP00000414089 UniProtKB/TrEMBL
Ensembl Transcript ENST00000216877 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000318266 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000356147 UniProtKB/Swiss-Prot
  ENST00000399903 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000430705 UniProtKB/TrEMBL
  ENST00000431048 UniProtKB/TrEMBL
  ENST00000455631 UniProtKB/TrEMBL
Gene3D-CATH 3.90.190.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000132670 GTEx
HGNC ID HGNC:9664 ENTREZGENE
Human Proteome Map PTPRA Human Proteome Map
InterPro Prot-tyrosine_phosphatase-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTPase_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_Pase_cat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_Pase_rcpt_a/e-type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_Pase_rcpt_alpha UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYR_PHOSPHATASE_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:5786 UniProtKB/Swiss-Prot
NCBI Gene 5786 ENTREZGENE
OMIM 176884 OMIM
PANTHER PTHR19134:SF433 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Y_phosphatase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA34009 PharmGKB
PIRSF PTPR_alpha UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTPR_alpha_epsilon UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS PRTYPHPHTASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE TYR_PHOSPHATASE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYR_PHOSPHATASE_PTP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PTPc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTPc_motif UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52799 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A1S5UZ22_HUMAN UniProtKB/TrEMBL
  P18433 ENTREZGENE, UniProtKB/Swiss-Prot
  Q5JWG0_HUMAN UniProtKB/TrEMBL
  Q5JWG2_HUMAN UniProtKB/TrEMBL
  Q5JWG3_HUMAN UniProtKB/TrEMBL
UniProt Secondary A8K2G8 UniProtKB/Swiss-Prot
  D3DVX5 UniProtKB/Swiss-Prot
  Q14513 UniProtKB/Swiss-Prot
  Q7Z2I2 UniProtKB/Swiss-Prot
  Q96TD9 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-02-19 PTPRA  protein tyrosine phosphatase receptor type A    protein tyrosine phosphatase, receptor type A  Symbol and/or name change 5135510 APPROVED
2016-01-12 PTPRA  protein tyrosine phosphatase, receptor type A    protein tyrosine phosphatase, receptor type, A  Symbol and/or name change 5135510 APPROVED
2011-08-16 PTPRA  protein tyrosine phosphatase, receptor type, A  PTPRA  protein tyrosine phosphatase, receptor type, A  Symbol and/or name change 5135510 APPROVED