(+)-Tetrandrine decreases expression EXP 6480464 tetrandrine results in decreased expression of GRB2 protein CTD PMID:30549224 1,2-dimethylhydrazine decreases expression ISO RGD:619758 6480464 1, 2-Dimethylhydrazine results in decreased expression of GRB2 mRNA CTD PMID:32387197 1,2-dimethylhydrazine decreases expression ISO RGD:732474 6480464 1, 2-Dimethylhydrazine results in decreased expression of GRB2 mRNA CTD PMID:22206623 1,2-dimethylhydrazine multiple interactions ISO RGD:732474 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of GRB2 mRNA CTD PMID:22206623 17alpha-ethynylestradiol multiple interactions ISO RGD:732474 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GRB2 mRNA CTD PMID:17942748 17alpha-ethynylestradiol increases expression ISO RGD:732474 6480464 Ethinyl Estradiol results in increased expression of GRB2 mRNA CTD PMID:17942748 17beta-estradiol multiple interactions ISO RGD:619758 6480464 [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased expression of GRB2 mRNA, [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased expression of GRB2 protein CTD PMID:22465879 17beta-estradiol multiple interactions EXP 6480464 IGF1R mutant form inhibits the reaction [Estradiol results in increased expression of GRB2 mRNA] CTD PMID:23094148 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of GRB2 mRNA CTD PMID:23094148 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:732474 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GRB2 mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:619758 6480464 CBL protein promotes the reaction [Tetrachlorodibenzodioxin promotes the reaction [GRB2 protein binds to SOS1 protein]] more ... CTD PMID:9918770 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:732474 6480464 Tetrachlorodibenzodioxin results in decreased expression of GRB2 mRNA CTD PMID:19465110 , PMID:22666406 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:732474 6480464 Tetrachlorodibenzodioxin affects the expression of GRB2 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:619758 6480464 Tetrachlorodibenzodioxin affects the expression of GRB2 mRNA CTD PMID:22298810 , PMID:34747641 3-chloropropane-1,2-diol decreases expression ISO RGD:619758 6480464 alpha-Chlorohydrin analog results in decreased expression of GRB2 protein CTD PMID:26597043 4,4'-sulfonyldiphenol increases expression EXP 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of GRB2 protein CTD PMID:34186270 4-hydroxyphenyl retinamide increases expression EXP 6480464 Fenretinide results in increased expression of GRB2 protein CTD PMID:15059897 aflatoxin B1 increases methylation EXP 6480464 Aflatoxin B1 results in increased methylation of GRB2 intron CTD PMID:30157460 Aflatoxin B2 alpha decreases methylation EXP 6480464 aflatoxin B2 results in decreased methylation of GRB2 intron CTD PMID:30157460 AICA ribonucleotide multiple interactions ISO RGD:619758 6480464 GRB2 protein affects the reaction [AICA ribonucleotide results in increased activity of PRKCZ protein] CTD PMID:11978788 all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of GRB2 mRNA CTD PMID:33167477 ammonium chloride affects expression ISO RGD:619758 6480464 Ammonium Chloride affects the expression of GRB2 mRNA CTD PMID:16483693 ammonium chloride decreases expression ISO RGD:619758 6480464 Ammonium Chloride results in decreased expression of GRB2 protein CTD PMID:16483693 antirheumatic drug decreases expression EXP 6480464 Antirheumatic Agents results in decreased expression of GRB2 mRNA CTD PMID:24449571 arsenic acid multiple interactions EXP 6480464 arsenic acid promotes the reaction [SHC1 protein binds to GRB2 protein] CTD PMID:14674888 arsenite(3-) multiple interactions EXP 6480464 arsenite promotes the reaction [SHC1 protein binds to GRB2 protein] CTD PMID:14674888 arsenous acid decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of GRB2 protein CTD PMID:25419056 arsenous acid increases expression EXP 6480464 Arsenic Trioxide results in increased expression of GRB2 mRNA CTD PMID:20458559 Benoxacor decreases expression ISO RGD:732474 6480464 benoxacor results in decreased expression of GRB2 mRNA CTD PMID:34850242 benzo[a]pyrene decreases expression ISO RGD:619758 6480464 Benzo(a)pyrene results in decreased expression of GRB2 protein CTD PMID:21467743 benzo[a]pyrene affects methylation EXP 6480464 Benzo(a)pyrene affects the methylation of GRB2 intron CTD PMID:30157460 benzo[e]pyrene decreases methylation EXP 6480464 benzo(e)pyrene results in decreased methylation of GRB2 intron CTD PMID:30157460 bisphenol A increases expression ISO RGD:619758 6480464 bisphenol A results in increased expression of GRB2 mRNA CTD PMID:25181051 , PMID:34947998 bisphenol A multiple interactions EXP 6480464 ESR1 protein affects the reaction [bisphenol A results in increased expression of GRB2 protein] CTD PMID:30615907 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of GRB2 protein CTD PMID:30615907 , PMID:34186270 bufalin decreases expression EXP 6480464 bufalin results in decreased expression of GRB2 protein CTD PMID:23949904 cadmium atom increases expression EXP 6480464 Cadmium results in increased expression of GRB2 protein CTD PMID:14499349 cadmium dichloride affects expression EXP 6480464 Cadmium Chloride affects the expression of GRB2 mRNA CTD PMID:33129824 calcitriol increases expression EXP 6480464 Calcitriol results in increased expression of GRB2 mRNA CTD PMID:15951637 cannabidiol multiple interactions EXP 6480464 [Cannabidiol co-treated with moringin] results in increased expression of GRB2 mRNA, [Oxygen co-treated with Ozone co-treated with Cannabidiol] results in decreased expression of GRB2 mRNA CTD PMID:30096889 , PMID:32992648 casticin decreases expression ISO RGD:732474 6480464 casticin results in decreased expression of GRB2 protein CTD PMID:28444820 cerium trichloride affects expression ISO RGD:732474 6480464 cerous chloride affects the expression of GRB2 mRNA CTD PMID:23139204 chlordecone decreases expression ISO RGD:732474 6480464 Chlordecone results in decreased expression of GRB2 mRNA CTD PMID:29980752 chlorpyrifos increases expression ISO RGD:732474 6480464 Chlorpyrifos results in increased expression of GRB2 mRNA CTD PMID:27737797 choline multiple interactions ISO RGD:619758 6480464 [Folic Acid deficiency co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of GRB2 protein CTD PMID:19566968 chrysin decreases expression EXP 6480464 chrysin results in decreased expression of GRB2 protein CTD PMID:30578657 clofibrate decreases expression ISO RGD:732474 6480464 Clofibrate results in decreased expression of GRB2 mRNA CTD PMID:23811191 cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of GRB2 mRNA CTD PMID:19376846 cocaine increases expression ISO RGD:619758 6480464 Cocaine results in increased expression of GRB2 protein CTD PMID:25100957 copper(II) sulfate increases expression EXP 6480464 Copper Sulfate results in increased expression of GRB2 mRNA CTD PMID:19549813 crocidolite asbestos affects expression EXP 6480464 Asbestos, Crocidolite affects the expression of GRB2 mRNA CTD PMID:17331233 curcumin decreases expression EXP 6480464 Curcumin analog results in decreased expression of GRB2 mRNA CTD PMID:26409325 cypermethrin decreases expression EXP 6480464 cypermethrin results in decreased expression of GRB2 mRNA CTD PMID:27704156 DDT multiple interactions EXP 6480464 DDT promotes the reaction [GRB2 protein binds to SOS1 protein] CTD PMID:9070211 decabromodiphenyl ether increases expression ISO RGD:619758 6480464 decabromobiphenyl ether results in increased expression of GRB2 mRNA CTD PMID:23640034 dexamethasone multiple interactions EXP 6480464 Dexamethasone inhibits the reaction [EGF protein promotes the reaction [EGFR protein binds to GRB2 protein]], Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [EGF protein promotes the reaction [EGFR protein binds to GRB2 protein]]] CTD PMID:10807665 dextran sulfate multiple interactions ISO RGD:732474 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GRB2 mRNA CTD PMID:29950665 diallyl disulfide affects expression EXP 6480464 diallyl disulfide affects the expression of GRB2 protein CTD PMID:21695758 diallyl disulfide decreases expression EXP 6480464 diallyl disulfide results in decreased expression of GRB2 protein CTD PMID:21695758 Diallyl sulfide decreases expression EXP 6480464 allyl sulfide results in decreased expression of GRB2 protein CTD PMID:21695758 diarsenic trioxide decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of GRB2 protein CTD PMID:25419056 diarsenic trioxide increases expression EXP 6480464 Arsenic Trioxide results in increased expression of GRB2 mRNA CTD PMID:20458559 dioxygen multiple interactions EXP 6480464 [Oxygen co-treated with Ozone co-treated with Cannabidiol] results in decreased expression of GRB2 mRNA, [Oxygen co-treated with Ozone] results in decreased expression of GRB2 mRNA CTD PMID:32992648 disodium selenite decreases expression EXP 6480464 Sodium Selenite results in decreased expression of GRB2 mRNA CTD PMID:16705456 disodium selenite increases expression EXP 6480464 Sodium Selenite results in increased expression of GRB2 mRNA CTD PMID:18175754 enzyme inhibitor multiple interactions EXP 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of GRB2 protein CTD PMID:23301498 ethanol affects splicing ISO RGD:732474 6480464 Ethanol affects the splicing of GRB2 mRNA CTD PMID:30319688 finasteride increases expression ISO RGD:619758 6480464 Finasteride results in increased expression of GRB2 mRNA CTD PMID:24136188 flavonoids increases expression ISO RGD:619758 6480464 Flavonoids results in increased expression of GRB2 mRNA CTD PMID:18035473 folic acid multiple interactions ISO RGD:732474 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of GRB2 mRNA CTD PMID:22206623 folic acid multiple interactions ISO RGD:619758 6480464 [Folic Acid deficiency co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of GRB2 protein CTD PMID:19566968 gallic acid decreases expression EXP 6480464 Gallic Acid results in decreased expression of GRB2 protein CTD PMID:22387266 genistein decreases expression EXP 6480464 Genistein results in decreased expression of GRB2 mRNA CTD PMID:16705744 genistein increases expression EXP 6480464 Genistein results in increased expression of GRB2 mRNA CTD PMID:20884965 gentamycin increases expression ISO RGD:619758 6480464 Gentamicins results in increased expression of GRB2 mRNA CTD PMID:22061828 glyphosate decreases expression EXP 6480464 glyphosate results in decreased expression of GRB2 mRNA CTD PMID:31295307 hydrogen peroxide affects expression EXP 6480464 Hydrogen Peroxide affects the expression of GRB2 mRNA CTD PMID:21179406 hydroquinone affects expression EXP 6480464 hydroquinone affects the expression of GRB2 protein CTD PMID:20021034 ivermectin decreases expression EXP 6480464 Ivermectin results in decreased expression of GRB2 protein CTD PMID:32959892 L-methionine multiple interactions ISO RGD:619758 6480464 [Folic Acid deficiency co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of GRB2 protein CTD PMID:19566968 letrozole increases expression ISO RGD:732474 6480464 letrozole results in increased expression of GRB2 protein CTD PMID:15967659 maneb multiple interactions ISO RGD:732474 6480464 [Maneb co-treated with Paraquat] results in decreased expression of GRB2 mRNA more ... CTD PMID:23963992 melatonin multiple interactions ISO RGD:732474 6480464 Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of GRB2 mRNA] CTD PMID:23963992 methamphetamine affects expression ISO RGD:619758 6480464 Methamphetamine affects the expression of GRB2 protein CTD PMID:17904249 methapyrilene decreases methylation EXP 6480464 Methapyrilene results in decreased methylation of GRB2 intron CTD PMID:30157460 microcystin-LR decreases expression ISO RGD:619758 6480464 cyanoginosin LR results in decreased expression of GRB2 protein CTD PMID:22430071 mifepristone multiple interactions EXP 6480464 Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [EGF protein promotes the reaction [EGFR protein binds to GRB2 protein]]] CTD PMID:10807665 N-methyl-N-nitrosourea multiple interactions ISO RGD:619758 6480464 [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased expression of GRB2 mRNA, [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased expression of GRB2 protein CTD PMID:22465879 nickel atom increases expression EXP 6480464 Nickel results in increased expression of GRB2 mRNA CTD PMID:24768652 , PMID:25583101 nitric oxide decreases expression ISO RGD:732474 6480464 Nitric Oxide deficiency results in decreased expression of GRB2 mRNA CTD PMID:15878706 Nonidet P-40 decreases expression EXP 6480464 Nonidet P-40 results in decreased expression of GRB2 mRNA CTD PMID:26552463 ouabain decreases expression EXP 6480464 Ouabain results in decreased expression of GRB2 protein CTD PMID:28795476 ozone increases expression ISO RGD:619758 6480464 Ozone results in increased expression of GRB2 protein CTD PMID:33146391 ozone multiple interactions EXP 6480464 [Oxygen co-treated with Ozone co-treated with Cannabidiol] results in decreased expression of GRB2 mRNA, [Oxygen co-treated with Ozone] results in decreased expression of GRB2 mRNA CTD PMID:32992648 p-menthan-3-ol decreases expression EXP 6480464 Menthol results in decreased expression of GRB2 mRNA CTD PMID:26760959 paracetamol affects expression ISO RGD:732474 6480464 Acetaminophen affects the expression of GRB2 mRNA CTD PMID:17562736 paracetamol affects expression ISO RGD:619758 6480464 Acetaminophen affects the expression of GRB2 mRNA CTD PMID:16701773 paraquat multiple interactions ISO RGD:732474 6480464 [Maneb co-treated with Paraquat] results in decreased expression of GRB2 mRNA more ... CTD PMID:23963992 perfluorooctanoic acid decreases expression ISO RGD:619758 6480464 perfluorooctanoic acid results in decreased expression of GRB2 mRNA CTD PMID:19162173 phenylarsine oxide multiple interactions ISO RGD:619758 6480464 [oxophenylarsine results in decreased phosphorylation of PLCG1 protein] inhibits the reaction [PLCG1 protein binds to GRB2 protein] CTD PMID:9281317 phosphane decreases expression ISO RGD:619758 6480464 phosphine results in decreased expression of GRB2 mRNA CTD PMID:34427094 pirinixic acid decreases expression ISO RGD:732474 6480464 pirinixic acid results in decreased expression of GRB2 mRNA CTD PMID:23811191 pregnenolone 16alpha-carbonitrile increases expression ISO RGD:732474 6480464 Pregnenolone Carbonitrile results in increased expression of GRB2 mRNA CTD PMID:28903501 progesterone multiple interactions ISO RGD:619758 6480464 [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased expression of GRB2 mRNA, [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased expression of GRB2 protein CTD PMID:22465879 propiconazole decreases expression ISO RGD:732474 6480464 propiconazole results in decreased expression of GRB2 mRNA CTD PMID:21278054 quercetin increases expression EXP 6480464 Quercetin results in increased expression of GRB2 mRNA CTD PMID:27514524 quercetin decreases expression EXP 6480464 Quercetin results in decreased expression of GRB2 protein CTD PMID:23645742 resveratrol decreases expression EXP 6480464 resveratrol results in decreased expression of GRB2 mRNA CTD PMID:12002526 resveratrol multiple interactions EXP 6480464 resveratrol promotes the reaction [[ITGAV protein binds to ITGB3 protein] which affects the localization of GRB2 protein] CTD PMID:21467134 rotenone decreases expression ISO RGD:619758 6480464 Rotenone results in decreased expression of GRB2 protein CTD PMID:35544339 S-butyl-DL-homocysteine (S,R)-sulfoximine decreases expression ISO RGD:732474 6480464 Buthionine Sulfoximine results in decreased expression of GRB2 mRNA CTD PMID:15878706 sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of GRB2 mRNA CTD PMID:12016162 , PMID:34032870 sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of GRB2 protein CTD PMID:30528433 sodium arsenite multiple interactions ISO RGD:619758 6480464 [sodium arsenite results in increased phosphorylation of SHC1 protein] promotes the reaction [SHC1 protein modified form binds to GRB2 protein], sodium arsenite promotes the reaction [SHC1 protein modified form binds to GRB2 protein] CTD PMID:9710602 sorafenib decreases expression EXP 6480464 sorafenib results in decreased expression of GRB2 mRNA CTD PMID:26409325 sulindac increases expression ISO RGD:619758 6480464 Sulindac results in increased expression of GRB2 mRNA CTD PMID:24136188 tert-butyl hydroperoxide increases expression EXP 6480464 tert-Butylhydroperoxide results in increased expression of GRB2 mRNA CTD PMID:15336504 titanium dioxide multiple interactions ISO RGD:732474 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GRB2 mRNA CTD PMID:29950665 trimethyltin increases expression ISO RGD:732474 6480464 trimethyltin results in increased expression of GRB2 mRNA CTD PMID:20833246 Triptolide decreases expression ISO RGD:732474 6480464 triptolide results in decreased expression of GRB2 protein CTD PMID:26420756 uranium atom affects expression EXP 6480464 Uranium affects the expression of GRB2 mRNA CTD PMID:15672453 valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of GRB2 mRNA CTD PMID:23179753
