Pigfal9 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Pigfal9 (Plasma insulin-like growth factor 1 level QTL 9) Rattus norvegicus

Symbol: Pigfal9
Name: Plasma insulin-like growth factor 1 level QTL 9
RGD ID: 8552928
Trait: blood insulin-like growth factor amount   (VT:0010479)    
Measurement Type: plasma insulin-like growth factor 1 level   (CMO:0001299)    
LOD Score: 9.0
P Value: Not Available
Variance: 15.4
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81733,104,645 - 78,104,645RGD_MAPPER_PIPELINE
mRatBN7.21728,409,147 - 73,409,147RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01730,975,228 - 75,975,228RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01728,671,746 - 73,671,746RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41736,604,895 - 81,604,895RGD_MAPPER_PIPELINERGSC3.4
Cross Type: intercross
Strains Crossed: F344/IcoCrlf LOU/NimrOlaHsd 
JBrowse: View Region in Genome Browser (JBrowse)
Model




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pigfal9Ratdisease of metabolism  IAGP 7794844 RGD 
Pigfal9RatInsulin-Like Growth Factor I Deficiency  IAGP 7794844 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pigfal9Ratabnormal circulating insulin-like growth factor I level  IDA 7794844 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pigfal9Ratplasma insulin-like growth factor 1 level  IDA 7794844 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pigfal9Ratcontrolled calorie content diet  IDA 7794844 RGD 
Pigfal9Ratfasting  IDA 7794844 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pigfal9Ratradioimmunoassay  IDA 7794844 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pigfal9RatF344/IcoCrlf  IEA 7794844 RGD 
Pigfal9RatLOU/NimrOlaHsd  IEA 7794844 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pigfal9Ratblood insulin-like growth factor amount  IDA 7794844 RGD 


#
Reference Title
Reference Citation
1. QTLs influencing IGF-1 levels in a LOU/CxFischer 344F2 rat population. Tracks towards the metabolic theory of Ageing. Marissal-Arvy N, etal., Growth Horm IGF Res. 2013 Dec;23(6):220-8. doi: 10.1016/j.ghir.2013.08.002. Epub 2013 Aug 19.


1 to 20 of 649 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1309416Fars2phenylalanyl-tRNA synthetase 2, mitochondrial172831921528746217Rat
7672286Lyrm4LYR motif containing 4172874645728861849Rat
41372163Hdac1-ps16Histone deacetylase 1, pseudogene 16172884967128850978Rat
1308930Ppp1r3gprotein phosphatase 1, regulatory subunit 3G172887495628878288Rat
1310228Rpp40ribonuclease P/MRP subunit p40172894775228956788Rat
1549745Cdylchromodomain Y-like172898200929204345Rat
41292709LOC120097861uncharacterized LOC120097861172912686329136858Rat
1589720Rps7-ps16ribosomal protein S7, pseudogene 16172926770129268243Rat
41025517LOC120097993small nucleolar RNA SNORA17172956217729562309Rat
1561689Erp29-ps1endoplasmic reticulum protein 29, pseudogene 1172962366029628679Rat
1359427Eci2enoyl-CoA delta isomerase 2172985088429886781Rat
1310224Eci3enoyl-Coenzyme A delta isomerase 3172992196229943864Rat
1307537Tex56ptestis expressed 56172992985529966578Rat
1566214Fam217afamily with sequence similarity 217, member A172997502529981455Rat
1307784Prpf4bpre-mRNA processing factor 4B172998534330020285Rat
1589719Hmgb1-ps2high mobility group box 1, pseudogene 2173004087930042758Rat
1563458Fam50bfamily with sequence similarity 50, member B173017443130193627Rat
1311307Pxdc1PX domain containing 1173027599830304971Rat
620302Slc22a23solute carrier family 22, member 23173054410630709790Rat
1589955Psmg4proteasome assembly chaperone 4173071068230718035Rat

1 to 20 of 649 rows
1 to 20 of 667 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
10119D17Arb4244173422548134225727Ratregion
10119D17Arb4244173422548134225872Ratregion
10119D17Arb4244173422556634225727Ratregion
10348D17Mit4231176046341260463643Ratregion
10349D17Arb7237176046340560463642Ratregion
10350D17Wox12137176046350060463637Ratregion
10351D17Wox13150176046348360463633Ratregion
10709D17Mgh3112174142981541429923Ratregion
11150D17Wox11134173787123537871375Ratregion
11151D17Wox18232173787115737871389Ratregion
33790D17Mit3194175348176653481960Ratregion
33860D17Mit10231175523786855238103Ratregion
33882D17Mit2129173199078431990913Ratregion
34120D17Mgh597175090909950909196Ratregion
34122D17Mgh8157175090909650909253Ratregion
34391D17Mgh9148176811706768117215Ratregion
34645D17Pas1339175278466452785007Ratregion
33707D17Mit5281177085256570852846Ratregion
35985D17Rat20163173852519738525360Ratregion
36011D17Rat17157173583708535837242Ratregion
1 to 20 of 667 rows

Peak: (D17Mgh5)
Rat AssemblyChrPosition (strand)Source
GRCr81755,604,597 - 55,604,694 (+)Marker Load Pipeline
mRatBN7.21750,909,099 - 50,909,196 (+)MAPPER
Rnor_6.01753,475,180 - 53,475,276NCBI
Rnor_5.01751,171,698 - 51,171,794UniSTS
RGSC_v3.41759,104,847 - 59,104,944RGD
RGSC_v3.41759,104,848 - 59,104,944UniSTS
RGSC_v3.11759,107,688 - 59,107,785RGD
Celera1746,929,911 - 46,930,007UniSTS
RH 3.4 Map17532.99UniSTS
RH 3.4 Map17532.99RGD
RH 2.0 Map17455.1RGD
SHRSP x BN Map1730.3699RGD
FHH x ACI Map1736.6499RGD
Cytogenetic Map17q12.1UniSTS


1 to 10 of 76 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1354640Scl32Serum cholesterol level QTL 325.4blood HDL cholesterol amount (VT:0000184)blood high density lipoprotein cholesterol level (CMO:0000052)171578159260781592Rat
7411575Bw140Body weight QTL 14030.20.001body mass (VT:0001259)body weight gain (CMO:0000420)174856093586533673Rat
1300123Bp194Blood pressure QTL 1942.82arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)17211514934551001Rat
7411577Bw141Body weight QTL 1410.001body mass (VT:0001259)body weight gain (CMO:0000420)176261951686533673Rat
2302377Scl61Serum cholesterol level QTL 614.36blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)172738994653481766Rat
1354654Spl7Serum phospholipid level QTL 75.5blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)175089090860781592Rat
70157Niddm32Non-insulin dependent diabetes mellitus QTL 324.34blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)172245492450909196Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
1598871Memor5Memory QTL 55.3exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)174054004180387013Rat
1354628Stl13Serum triglyceride level QTL 133.8blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)172129303960781592Rat

1 to 10 of 76 rows


Note Type Note Reference
qtl_general number of animals used: 93 F2 males 7794844
qtl_general software package used: ANOVA; MultiQTL software 7794844
qtl_general measurement method: 4 weeks old rats were fed SAFE-A03 chow; at 18 weeks of age they were fasted overnight, decapitated in the morning and blood samples taken; total Igf-1 level determined by radioimmunoassay 7794844
qtl_general confidence interval from 80.73-92.90 Mb 7794844