Svil (supervillin) - Rat Genome Database

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Gene: Svil (supervillin) Rattus norvegicus
Analyze
Symbol: Svil
Name: supervillin
RGD ID: 1306354
Description: Predicted to have actin filament binding activity and phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to be involved in several processes, including actin filament severing; actin polymerization or depolymerization; and barbed-end actin filament capping. Predicted to localize to several cellular components, including actin cytoskeleton; costamere; and cytosol. Human ortholog(s) of this gene implicated in myofibrillar myopathy 10. Orthologous to human SVIL (supervillin); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC361256
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21752,648,502 - 52,844,114 (-)NCBI
Rnor_6.0 Ensembl1755,230,298 - 55,346,279 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01755,230,298 - 55,425,967 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01752,915,519 - 53,109,502 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41760,897,631 - 60,898,874 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11760,908,466 - 60,983,517 (-)NCBI
Celera1748,653,106 - 48,767,953 (-)NCBICelera
Cytogenetic Map17q12.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(2,4,5-trichlorophenoxy)acetic acid  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dinitrotoluene  (EXP)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
8-Br-cAMP  (ISO)
acrolein  (ISO)
acrylamide  (EXP)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
alpha-pinene  (ISO)
amiodarone  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
carbon nanotube  (ISO)
choline  (ISO)
ciguatoxin CTX1B  (ISO)
clomiphene  (ISO)
cobalt dichloride  (EXP,ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
diethylstilbestrol  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
estrone  (ISO)
ethanol  (EXP,ISO)
fenamidone  (ISO)
fenvalerate  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
gentamycin  (EXP)
hexestrol  (ISO)
L-methionine  (ISO)
mestranol  (ISO)
methamphetamine  (ISO)
methyl methanesulfonate  (ISO)
methylseleninic acid  (ISO)
mifepristone  (ISO)
nefazodone  (EXP)
nimesulide  (EXP)
oxaliplatin  (EXP)
ozone  (EXP,ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium fluoride  (ISO)
sunitinib  (ISO)
topotecan  (EXP)
trichloroethene  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (EXP)
tris(2-butoxyethyl) phosphate  (ISO)
troglitazone  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
actin cytoskeleton  (IBA,ISO)
costamere  (ISO)
cytoplasm  (IBA,ISO)
cytosol  (IEA,ISO)
nucleus  (ISO)
plasma membrane  (IEA,ISO)

Molecular Function

References

Additional References at PubMed
PMID:12711699   PMID:21423176   PMID:24625528  


Genomics

Comparative Map Data
Svil
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21752,648,502 - 52,844,114 (-)NCBI
Rnor_6.0 Ensembl1755,230,298 - 55,346,279 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01755,230,298 - 55,425,967 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01752,915,519 - 53,109,502 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41760,897,631 - 60,898,874 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11760,908,466 - 60,983,517 (-)NCBI
Celera1748,653,106 - 48,767,953 (-)NCBICelera
Cytogenetic Map17q12.1NCBI
SVIL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1029,457,338 - 29,736,959 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl1029,457,338 - 29,736,781 (-)EnsemblGRCh38hg38GRCh38
GRCh381029,457,338 - 29,736,936 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371029,746,267 - 30,025,865 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361029,786,283 - 30,064,736 (-)NCBINCBI36hg18NCBI36
Build 341029,786,282 - 29,963,907NCBI
Celera1029,511,358 - 29,789,724 (-)NCBI
Cytogenetic Map10p11.23NCBI
HuRef1029,465,586 - 29,744,249 (-)NCBIHuRef
CHM1_11029,746,277 - 30,025,834 (-)NCBICHM1_1
Svil
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39184,920,497 - 5,119,293 (+)NCBIGRCm39mm39
GRCm39 Ensembl184,920,540 - 5,119,299 (+)Ensembl
GRCm38184,920,467 - 5,119,293 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl184,920,540 - 5,119,299 (+)EnsemblGRCm38mm10GRCm38
MGSCv37185,046,587 - 5,119,291 (+)NCBIGRCm37mm9NCBIm37
MGSCv36184,920,565 - 5,119,288 (+)NCBImm8
Celera185,092,122 - 5,164,709 (+)NCBICelera
Cytogenetic Map18A1NCBI
Svil
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542922,370,458 - 22,464,579 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542922,339,739 - 22,465,471 (+)NCBIChiLan1.0ChiLan1.0
LOC100977039
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11029,965,789 - 30,241,150 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1029,965,792 - 30,064,765 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01029,609,492 - 29,886,920 (-)NCBIMhudiblu_PPA_v0panPan3
SVIL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1216,004,160 - 16,234,434 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl216,004,951 - 16,174,218 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha213,491,738 - 13,728,974 (-)NCBI
ROS_Cfam_1.0214,241,118 - 14,472,207 (-)NCBI
UMICH_Zoey_3.1213,679,909 - 13,916,712 (-)NCBI
UNSW_CanFamBas_1.0213,571,334 - 13,802,471 (-)NCBI
UU_Cfam_GSD_1.0213,845,719 - 13,949,060 (-)NCBI
Svil
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093449,841,704 - 9,989,550 (+)NCBI
SpeTri2.0NW_0049366134,391,928 - 4,540,125 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SVIL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1041,177,977 - 41,462,766 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11041,176,358 - 41,462,750 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21045,876,765 - 46,002,098 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Svil
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248053,111,789 - 3,321,459 (+)NCBI

Position Markers
D17Pas1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21752,784,664 - 52,785,007 (+)MAPPER
Rnor_6.01755,365,404 - 55,365,742NCBIRnor6.0
Rnor_5.01753,049,993 - 53,050,331UniSTSRnor5.0
RGSC_v3.41761,036,124 - 61,036,462UniSTSRGSC3.4
Celera1748,785,245 - 48,785,573UniSTS
Celera1748,785,245 - 48,785,917UniSTS
RH 3.4 Map17535.49UniSTS
Cytogenetic Map17q12.1UniSTS
D17Rat57  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21752,778,565 - 52,778,744 (+)MAPPER
Rnor_6.01755,359,306 - 55,359,484NCBIRnor6.0
Rnor_5.01753,043,895 - 53,044,073UniSTSRnor5.0
RGSC_v3.41761,030,025 - 61,030,204RGDRGSC3.4
RGSC_v3.41761,030,026 - 61,030,204UniSTSRGSC3.4
RGSC_v3.11761,040,859 - 61,041,037RGD
Celera1748,779,148 - 48,779,324UniSTS
RH 3.4 Map17556.8UniSTS
RH 3.4 Map17556.8RGD
FHH x ACI Map1738.8399UniSTS
FHH x ACI Map1738.8399RGD
Cytogenetic Map17q12.1UniSTS
BF405465  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21752,779,890 - 52,780,097 (+)MAPPER
Rnor_6.01755,360,630 - 55,360,836NCBIRnor6.0
Rnor_5.01753,045,219 - 53,045,425UniSTSRnor5.0
RGSC_v3.41761,031,351 - 61,031,557UniSTSRGSC3.4
Celera1748,780,471 - 48,780,677UniSTS
RH 3.4 Map17537.29UniSTS
Cytogenetic Map17q12.1UniSTS
RH131282  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21752,659,981 - 52,660,198 (+)MAPPER
Rnor_6.01755,241,487 - 55,241,703NCBIRnor6.0
Rnor_5.01752,926,708 - 52,926,924UniSTSRnor5.0
RGSC_v3.41760,909,577 - 60,909,793UniSTSRGSC3.4
Celera1748,664,355 - 48,664,571UniSTS
Cytogenetic Map17q12.1UniSTS
RH133470  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21752,648,636 - 52,648,829 (+)MAPPER
Rnor_6.01755,230,433 - 55,230,625NCBIRnor6.0
Rnor_5.01752,915,654 - 52,915,846UniSTSRnor5.0
RGSC_v3.41760,897,746 - 60,897,938UniSTSRGSC3.4
Celera1748,653,241 - 48,653,433UniSTS
RH 3.4 Map17536.69UniSTS
Cytogenetic Map17q12.1UniSTS
D10S1311E  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21752,656,260 - 52,657,176 (+)MAPPER
Rnor_6.01755,238,061 - 55,238,976NCBIRnor6.0
Rnor_5.01752,923,282 - 52,924,197UniSTSRnor5.0
RGSC_v3.41760,905,374 - 60,906,289UniSTSRGSC3.4
Celera1748,660,855 - 48,661,770UniSTS
Cytogenetic Map17q12.1UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17163676140Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17173413148Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17173413148Rat
1354596Bw32Body weight QTL 324.5body mass (VT:0001259)body weight (CMO:0000012)17333697263676140Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)17333697273413148Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17333697273413148Rat
1354630Cm34Cardiac mass QTL 348.7heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)17333697273413148Rat
1331765Hrtrt15Heart rate QTL 154.094heart pumping trait (VT:2000009)heart rate (CMO:0000002)171574375561036897Rat
1354640Scl32Serum cholesterol level QTL 325.4blood HDL cholesterol amount (VT:0000184)blood high density lipoprotein cholesterol level (CMO:0000052)171867614063676140Rat
1354659Scl68Serum cholesterol level QTL 683.9blood VLDL cholesterol amount (VT:0005144)blood very low density lipoprotein cholesterol level (CMO:0000648)171867614063676140Rat
7488966Bp370Blood pressure QTL 3700.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172149095062195822Rat
1559055Bp278Blood pressure QTL 2780.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172149095066490950Rat
12903978Cm118Cardiac mass QTL 1180.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)172149095066490950Rat
12903979Cm119Cardiac mass QTL 1190.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172149095066490950Rat
12903980Cm120Cardiac mass QTL 1200.002heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)172149095066490950Rat
12903981Am17Aortic mass QTL 170.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)172149095066490950Rat
12903982Kidm70Kidney mass QTL 700.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)172149095074823273Rat
61394Bp8Blood pressure QTL 82.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172277506564946194Rat
1354628Stl13Serum triglyceride level QTL 133.8blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)172403061863676140Rat
1581512Cm55Cardiac mass QTL 552.80.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172769095961794615Rat
4889955Bss93Bone structure and strength QTL 934.4tibia size trait (VT:0100001)tibia cortical bone volume to tibia total bone volume ratio (CMO:0001727)172769095963994435Rat
2302377Scl61Serum cholesterol level QTL 614.36blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)172807358956207236Rat
1354619Bp242Blood pressure QTL 2426.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172841314873413148Rat
9590107Sffal7Serum free fatty acids level QTL 74.810.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)173097522875975228Rat
8552928Pigfal9Plasma insulin-like growth factor 1 level QTL 99blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)173097522875975228Rat
10450503Bp386Blood pressure QTL 3860.28arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)173205588258468016Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)173205588277922655Rat
724549Niddm56Non-insulin dependent diabetes mellitus QTL 560.03blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)173330362778303627Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173330362785321557Rat
1300148Bp192Blood pressure QTL 1923.47arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)173628324577922655Rat
724528Uae4Urinary albumin excretion QTL 44.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)173779030673413148Rat
2317054Aia12Adjuvant induced arthritis QTL 124.24joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)174117605786176057Rat
2317060Aia26Adjuvant induced arthritis QTL 263.22joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)174117605786176057Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)174173108086731080Rat
1598871Memor5Memory QTL 55.3exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)174254187285446768Rat
631497Bp98Blood pressure QTL 983.66arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)174295602163994435Rat
1358295Aocep1Aortic cell protein QTL 16.10.00000071thoracic aorta cellular protein amount (VT:0010598)aortic cell percentage174435615789356157Rat
1354635Bp245Blood pressure QTL 2456arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)174866025273413148Rat
1354635Bp245Blood pressure QTL 2456arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)174866025273413148Rat
7411575Bw140Body weight QTL 14030.20.001body mass (VT:0001259)body weight gain (CMO:0000420)175241095790843779Rat
8694181Bw151Body weight QTL 1514.360.001body mass (VT:0001259)body weight gain (CMO:0000420)175241095790843779Rat
4889894Eae33Experimental allergic encephalomyelitis QTL 335.20.0001nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)175347518090690466Rat
2317053Aia25Adjuvant induced arthritis QTL 252.69joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)175347527663675975Rat
2317038Ginf3Gastrointestinal inflammation QTL 32.890.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)175387148890843779Rat
2303580Gluco49Glucose level QTL 492blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)175399194790843779Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:228
Count of miRNA genes:157
Interacting mature miRNAs:170
Transcripts:ENSRNOT00000025037, ENSRNOT00000050687, ENSRNOT00000064331
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 36 26 18 26 8 11 49 23 34 11 8
Low 21 15 1 15 25 12 7
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001108416 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006254030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006254031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008771737 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008771739 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600615 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600622 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600625 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600626 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095912 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095915 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095916 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095918 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095919 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000293 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000025037   ⟹   ENSRNOP00000025037
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1755,230,298 - 55,346,279 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000064331   ⟹   ENSRNOP00000062712
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1755,230,847 - 55,300,998 (-)Ensembl
RefSeq Acc Id: NM_001108416   ⟹   NP_001101886
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21752,648,502 - 52,767,260 (-)NCBI
Rnor_6.01755,230,298 - 55,346,279 (-)NCBI
Rnor_5.01752,915,519 - 53,109,502 (-)NCBI
RGSC_v3.41760,897,631 - 60,898,874 (-)RGD
Celera1748,653,106 - 48,767,953 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006254030   ⟹   XP_006254092
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21752,648,509 - 52,844,114 (-)NCBI
Rnor_6.01755,230,298 - 55,425,967 (-)NCBI
Rnor_5.01752,915,519 - 53,109,502 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006254031   ⟹   XP_006254093
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21752,648,509 - 52,767,758 (-)NCBI
Rnor_6.01755,230,298 - 55,348,025 (-)NCBI
Rnor_5.01752,915,519 - 53,109,502 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008771737   ⟹   XP_008769959
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01755,230,298 - 55,380,898 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008771739   ⟹   XP_008769961
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21752,648,509 - 52,844,114 (-)NCBI
Rnor_6.01755,230,298 - 55,425,967 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600615   ⟹   XP_017456104
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21752,648,509 - 52,766,067 (-)NCBI
Rnor_6.01755,230,298 - 55,307,299 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600616   ⟹   XP_017456105
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21752,648,509 - 52,766,067 (-)NCBI
Rnor_6.01755,230,298 - 55,307,299 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600617   ⟹   XP_017456106
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21752,648,509 - 52,766,067 (-)NCBI
Rnor_6.01755,230,298 - 55,307,299 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600618   ⟹   XP_017456107
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21752,648,509 - 52,766,067 (-)NCBI
Rnor_6.01755,230,298 - 55,307,299 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600619   ⟹   XP_017456108
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21752,648,509 - 52,766,067 (-)NCBI
Rnor_6.01755,230,298 - 55,307,299 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600620   ⟹   XP_017456109
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01755,230,298 - 55,310,127 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600621   ⟹   XP_017456110
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21752,648,509 - 52,725,693 (-)NCBI
Rnor_6.01755,230,298 - 55,307,299 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600622   ⟹   XP_017456111
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01755,230,298 - 55,307,299 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600623   ⟹   XP_017456112
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21752,648,509 - 52,725,693 (-)NCBI
Rnor_6.01755,230,298 - 55,307,299 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600624   ⟹   XP_017456113
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21752,648,509 - 52,725,693 (-)NCBI
Rnor_6.01755,230,298 - 55,307,299 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600625   ⟹   XP_017456114
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21752,648,509 - 52,725,693 (-)NCBI
Rnor_6.01755,230,298 - 55,307,299 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600626   ⟹   XP_017456115
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21752,648,509 - 52,725,693 (-)NCBI
Rnor_6.01755,230,298 - 55,307,299 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600627   ⟹   XP_017456116
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21752,648,509 - 52,725,693 (-)NCBI
Rnor_6.01755,230,298 - 55,307,299 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039095912   ⟹   XP_038951840
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21752,648,509 - 52,767,758 (-)NCBI
RefSeq Acc Id: XM_039095914   ⟹   XP_038951842
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21752,648,509 - 52,766,067 (-)NCBI
RefSeq Acc Id: XM_039095915   ⟹   XP_038951843
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21752,648,509 - 52,766,668 (-)NCBI
RefSeq Acc Id: XM_039095916   ⟹   XP_038951844
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21752,648,509 - 52,829,779 (-)NCBI
RefSeq Acc Id: XM_039095917   ⟹   XP_038951845
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21752,648,509 - 52,782,072 (-)NCBI
RefSeq Acc Id: XM_039095918   ⟹   XP_038951846
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21752,648,509 - 52,725,693 (-)NCBI
RefSeq Acc Id: XM_039095919   ⟹   XP_038951847
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21752,648,509 - 52,725,693 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001101886 (Get FASTA)   NCBI Sequence Viewer  
  XP_006254092 (Get FASTA)   NCBI Sequence Viewer  
  XP_006254093 (Get FASTA)   NCBI Sequence Viewer  
  XP_008769961 (Get FASTA)   NCBI Sequence Viewer  
  XP_017456104 (Get FASTA)   NCBI Sequence Viewer  
  XP_017456105 (Get FASTA)   NCBI Sequence Viewer  
  XP_017456106 (Get FASTA)   NCBI Sequence Viewer  
  XP_017456107 (Get FASTA)   NCBI Sequence Viewer  
  XP_017456108 (Get FASTA)   NCBI Sequence Viewer  
  XP_017456110 (Get FASTA)   NCBI Sequence Viewer  
  XP_017456112 (Get FASTA)   NCBI Sequence Viewer  
  XP_017456113 (Get FASTA)   NCBI Sequence Viewer  
  XP_017456114 (Get FASTA)   NCBI Sequence Viewer  
  XP_017456115 (Get FASTA)   NCBI Sequence Viewer  
  XP_017456116 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951840 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951842 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951843 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951844 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951845 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951846 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951847 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL87446 (Get FASTA)   NCBI Sequence Viewer  
  EDL87447 (Get FASTA)   NCBI Sequence Viewer  
  EDL87448 (Get FASTA)   NCBI Sequence Viewer  
  EDL87449 (Get FASTA)   NCBI Sequence Viewer  
  EDL87450 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001101886   ⟸   NM_001108416
- UniProtKB: F1M155 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006254092   ⟸   XM_006254030
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_006254093   ⟸   XM_006254031
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_008769961   ⟸   XM_008771739
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_008769959   ⟸   XM_008771737
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_017456109   ⟸   XM_017600620
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_017456116   ⟸   XM_017600627
- Peptide Label: isoform X17
- Sequence:
RefSeq Acc Id: XP_017456115   ⟸   XM_017600626
- Peptide Label: isoform X16
- Sequence:
RefSeq Acc Id: XP_017456114   ⟸   XM_017600625
- Peptide Label: isoform X15
- Sequence:
RefSeq Acc Id: XP_017456111   ⟸   XM_017600622
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_017456112   ⟸   XM_017600623
- Peptide Label: isoform X12
- Sequence:
RefSeq Acc Id: XP_017456104   ⟸   XM_017600615
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017456113   ⟸   XM_017600624
- Peptide Label: isoform X13
- Sequence:
RefSeq Acc Id: XP_017456110   ⟸   XM_017600621
- Peptide Label: isoform X10
- UniProtKB: D3ZEZ9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456108   ⟸   XM_017600619
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_017456106   ⟸   XM_017600617
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_017456107   ⟸   XM_017600618
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_017456105   ⟸   XM_017600616
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSRNOP00000062712   ⟸   ENSRNOT00000064331
RefSeq Acc Id: ENSRNOP00000025037   ⟸   ENSRNOT00000025037
RefSeq Acc Id: XP_038951844   ⟸   XM_039095916
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038951845   ⟸   XM_039095917
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038951840   ⟸   XM_039095912
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038951843   ⟸   XM_039095915
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038951842   ⟸   XM_039095914
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038951847   ⟸   XM_039095919
- Peptide Label: isoform X14
RefSeq Acc Id: XP_038951846   ⟸   XM_039095918
- Peptide Label: isoform X11
Protein Domains
HP

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700524
Promoter ID:EPDNEW_R11046
Type:single initiation site
Name:Svil_1
Description:supervillin
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01755,346,257 - 55,346,317EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306354 AgrOrtholog
Ensembl Genes ENSRNOG00000018110 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000025037 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000062712 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000025037 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000064331 UniProtKB/TrEMBL
Gene3D-CATH 1.10.950.10 UniProtKB/TrEMBL
  3.40.20.10 UniProtKB/TrEMBL
InterPro ADF-H/Gelsolin-like_dom UniProtKB/TrEMBL
  Gelsolin UniProtKB/TrEMBL
  Gelsolin_dom UniProtKB/TrEMBL
  Supervillin UniProtKB/TrEMBL
  Villin_headpiece UniProtKB/TrEMBL
  Villin_headpiece_dom_sf UniProtKB/TrEMBL
KEGG Report rno:361256 UniProtKB/TrEMBL
NCBI Gene 361256 ENTREZGENE
PANTHER PTHR11977 UniProtKB/TrEMBL
  PTHR11977:SF86 UniProtKB/TrEMBL
Pfam Gelsolin UniProtKB/TrEMBL
  VHP UniProtKB/TrEMBL
PhenoGen Svil PhenoGen
PRINTS GELSOLIN UniProtKB/TrEMBL
PROSITE PS51089 UniProtKB/TrEMBL
SMART GEL UniProtKB/TrEMBL
  VHP UniProtKB/TrEMBL
Superfamily-SCOP VHP UniProtKB/TrEMBL
UniProt D3ZEZ9 ENTREZGENE, UniProtKB/TrEMBL
  F1M155 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Svil  supervillin   Svil_predicted  supervillin (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Svil_predicted  supervillin (predicted)      Symbol and Name status set to approved 70820 APPROVED