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Gene: Nqo2 (N-ribosyldihydronicotinamide:quinone reductase 2) Rattus norvegicus
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Symbol: Nqo2
Name: N-ribosyldihydronicotinamide:quinone reductase 2
Description: Predicted to have several functions, including anion binding activity; melatonin binding activity; and oxidoreductase activity. Involved in several processes, including positive regulation of cellular metabolic process; positive regulation of neuron apoptotic process; and positive regulation of vascular smooth muscle cell proliferation. Predicted to localize to the cytosol and nucleoplasm. Human ortholog(s) of this gene implicated in Parkinson's disease; agranulocytosis; breast cancer; and breast carcinoma. Orthologous to human NQO2 (N-ribosyldihydronicotinamide:quinone reductase 2); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MGC94180; NAD(P)H dehydrogenase, quinone 2; NAD(P)H quinone dehydrogenase 2; NRH dehydrogenase [quinone] 2; NRH:quinone oxidoreductase 2; QR2; quinone reductase 2; ribosyldihydronicotinamide dehydrogenase; ribosyldihydronicotinamide dehydrogenase [quinone]
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01732,131,847 - 32,158,559 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1732,132,347 - 32,158,538 (-)Ensembl
Rnor_5.01734,023,011 - 34,051,834 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41737,255,630 - 37,283,753 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11737,258,472 - 37,286,594 (-)NCBI
Celera1730,474,024 - 30,502,465 (-)NCBICelera
Cytogenetic Map17p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Nqo2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1303320
Created: 2004-12-03
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.