Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-dexrazoxane | multiple interactions | ISO | Bphl (Mus musculus) | 6480464 | [Doxorubicin co-treated with Dexrazoxane] results in increased expression of BPHL mRNA | CTD | PMID:26873546 | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of BPHL mRNA] | CTD | PMID:31150632 | (1->4)-beta-D-glucan | multiple interactions | ISO | Bphl (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of BPHL mRNA | CTD | PMID:36331819 | 1,1-dichloroethene | decreases expression | ISO | Bphl (Mus musculus) | 6480464 | vinylidene chloride results in decreased expression of BPHL mRNA | CTD | PMID:26682919 | 1,2-dimethylhydrazine | multiple interactions | ISO | Bphl (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of BPHL mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | decreases expression | ISO | Bphl (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of BPHL mRNA | CTD | PMID:22206623 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of BPHL mRNA | CTD | PMID:21215274 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of BPHL mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Bphl (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of BPHL mRNA | CTD | PMID:21570461 | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 6-dinitrotoluene affects the expression of BPHL mRNA | CTD | PMID:21346803 | 2-methylcholine | affects expression | ISO | BPHL (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of BPHL mRNA | CTD | PMID:21179406 | 3-chloropropane-1,2-diol | decreases expression | EXP | | 6480464 | alpha-Chlorohydrin results in decreased expression of BPHL protein | CTD | PMID:34915118 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of BPHL mRNA | CTD | PMID:30047161 | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of BPHL mRNA | CTD | PMID:31881176 | aflatoxin B1 | affects expression | ISO | BPHL (Homo sapiens) | 6480464 | Aflatoxin B1 affects the expression of BPHL protein | CTD | PMID:20106945 | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of BPHL mRNA | CTD | PMID:33354967 | aflatoxin B1 | decreases expression | ISO | BPHL (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of BPHL mRNA | CTD | PMID:22100608 and PMID:27153756 | aflatoxin B1 | decreases expression | ISO | Bphl (Mus musculus) | 6480464 | Aflatoxin B1 results in decreased expression of BPHL mRNA | CTD | PMID:19770486 | all-trans-retinoic acid | decreases expression | ISO | BPHL (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of BPHL mRNA | CTD | PMID:33167477 | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of BPHL mRNA | CTD | PMID:30047161 | antimycin A | decreases expression | ISO | BPHL (Homo sapiens) | 6480464 | Antimycin A results in decreased expression of BPHL mRNA | CTD | PMID:33512557 | aristolochic acid A | decreases expression | ISO | BPHL (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of BPHL mRNA | CTD | PMID:33212167 | atrazine | decreases expression | ISO | BPHL (Homo sapiens) | 6480464 | Atrazine results in decreased expression of BPHL mRNA | CTD | PMID:22378314 | benzo[a]pyrene | decreases expression | ISO | BPHL (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of BPHL mRNA | CTD | PMID:22316170 and PMID:32234424 | benzo[a]pyrene | decreases methylation | ISO | BPHL (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of BPHL promoter | CTD | PMID:27901495 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of BPHL mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | BPHL (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of BPHL protein | CTD | PMID:34186270 | bisphenol A | increases expression | ISO | Bphl (Mus musculus) | 6480464 | bisphenol A results in increased expression of BPHL mRNA | CTD | PMID:33221593 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of BPHL mRNA | CTD | PMID:34947998 | bisphenol A | affects expression | ISO | BPHL (Homo sapiens) | 6480464 | bisphenol A affects the expression of BPHL mRNA | CTD | PMID:30903817 | cadmium atom | increases expression | ISO | BPHL (Homo sapiens) | 6480464 | Cadmium results in increased expression of BPHL mRNA | CTD | PMID:24376830 | cadmium atom | multiple interactions | ISO | BPHL (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of BPHL mRNA | CTD | PMID:35301059 | cadmium dichloride | multiple interactions | ISO | BPHL (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of BPHL mRNA | CTD | PMID:35301059 | carbon nanotube | decreases expression | ISO | Bphl (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | choline | multiple interactions | ISO | Bphl (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of BPHL gene | CTD | PMID:20938992 | cisplatin | multiple interactions | ISO | BPHL (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of BPHL mRNA | CTD | PMID:27392435 | clofibric acid | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of BPHL mRNA | CTD | PMID:17602206 | cobalt dichloride | decreases expression | EXP | | 6480464 | cobaltous chloride results in decreased expression of BPHL mRNA | CTD | PMID:24386269 | copper(II) sulfate | decreases expression | ISO | BPHL (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of BPHL mRNA | CTD | PMID:19549813 | cyclosporin A | decreases expression | ISO | Bphl (Mus musculus) | 6480464 | Cyclosporine results in decreased expression of BPHL mRNA | CTD | PMID:23830897 | cyclosporin A | decreases expression | ISO | BPHL (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of BPHL mRNA | CTD | PMID:20106945 more ... | deguelin | decreases expression | ISO | BPHL (Homo sapiens) | 6480464 | deguelin results in decreased expression of BPHL mRNA | CTD | PMID:33512557 | dibutyl phthalate | decreases expression | ISO | Bphl (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of BPHL mRNA | CTD | PMID:17361019 and PMID:21266533 | dioxygen | multiple interactions | ISO | Bphl (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of BPHL mRNA | CTD | PMID:30529165 | diuron | decreases expression | EXP | | 6480464 | Diuron results in decreased expression of BPHL mRNA | CTD | PMID:21551480 | doxorubicin | decreases expression | ISO | Bphl (Mus musculus) | 6480464 | Doxorubicin results in decreased expression of BPHL mRNA | CTD | PMID:26873546 | doxorubicin | decreases expression | ISO | BPHL (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of BPHL mRNA | CTD | PMID:29803840 | doxorubicin | multiple interactions | ISO | Bphl (Mus musculus) | 6480464 | [Doxorubicin co-treated with Dexrazoxane] results in increased expression of BPHL mRNA | CTD | PMID:26873546 | fenpyroximate | decreases expression | ISO | BPHL (Homo sapiens) | 6480464 | fenpyroximate results in decreased expression of BPHL mRNA | CTD | PMID:33512557 | folic acid | multiple interactions | ISO | Bphl (Mus musculus) | 6480464 | [1 more ... | CTD | PMID:20938992 and PMID:22206623 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of BPHL mRNA | CTD | PMID:33387578 | glafenine | decreases expression | EXP | | 6480464 | Glafenine results in decreased expression of BPHL mRNA | CTD | PMID:24136188 | inulin | multiple interactions | ISO | Bphl (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of BPHL mRNA | CTD | PMID:36331819 | L-methionine | multiple interactions | ISO | Bphl (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of BPHL gene | CTD | PMID:20938992 | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of BPHL mRNA | CTD | PMID:30467583 | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of BPHL mRNA | CTD | PMID:30047161 | methylmercury chloride | decreases expression | ISO | BPHL (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of BPHL mRNA | CTD | PMID:28001369 | N,N-diethyl-m-toluamide | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in decreased methylation of BPHL gene | CTD | PMID:33148267 | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of BPHL mRNA | CTD | PMID:17602206 | nickel atom | decreases expression | ISO | BPHL (Homo sapiens) | 6480464 | Nickel results in decreased expression of BPHL mRNA | CTD | PMID:25583101 | nitrofen | increases expression | EXP | | 6480464 | nitrofen results in increased expression of BPHL mRNA | CTD | PMID:26720608 | ozone | increases expression | EXP | | 6480464 | Ozone results in increased expression of BPHL protein | CTD | PMID:33146391 | paracetamol | affects expression | ISO | Bphl (Mus musculus) | 6480464 | Acetaminophen affects the expression of BPHL mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | ISO | BPHL (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of BPHL mRNA | CTD | PMID:29067470 | paracetamol | increases expression | ISO | BPHL (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of BPHL mRNA | CTD | PMID:25704631 | paraquat | decreases expression | EXP | | 6480464 | Paraquat results in decreased expression of BPHL mRNA | CTD | PMID:32680482 | perfluorononanoic acid | decreases expression | ISO | BPHL (Homo sapiens) | 6480464 | perfluoro-n-nonanoic acid results in decreased expression of BPHL mRNA | CTD | PMID:32588087 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Bphl (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of BPHL mRNA more ... | CTD | PMID:36331819 | perfluorooctanoic acid | increases expression | ISO | BPHL (Homo sapiens) | 6480464 | perfluorooctanoic acid results in increased expression of BPHL protein | CTD | PMID:26879310 | perfluorooctanoic acid | decreases expression | ISO | BPHL (Homo sapiens) | 6480464 | perfluorooctanoic acid results in decreased expression of BPHL mRNA | CTD | PMID:36326898 | permethrin | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in decreased methylation of BPHL gene | CTD | PMID:33148267 | picoxystrobin | decreases expression | ISO | BPHL (Homo sapiens) | 6480464 | picoxystrobin results in decreased expression of BPHL mRNA | CTD | PMID:33512557 | pirinixic acid | multiple interactions | ISO | Bphl (Mus musculus) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of BPHL mRNA | CTD | PMID:19710929 | pirinixic acid | increases expression | ISO | Bphl (Mus musculus) | 6480464 | pirinixic acid results in increased expression of BPHL mRNA | CTD | PMID:17426115 | pregnenolone 16alpha-carbonitrile | decreases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in decreased expression of BPHL mRNA | CTD | PMID:30047161 | sodium arsenite | increases expression | ISO | BPHL (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of BPHL mRNA | CTD | PMID:22714537 | sodium arsenite | decreases expression | ISO | Bphl (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of BPHL mRNA | CTD | PMID:37682722 | sodium arsenite | increases expression | EXP | | 6480464 | sodium arsenite results in increased expression of BPHL protein | CTD | PMID:29459688 | sodium dichromate | decreases expression | EXP | | 6480464 | sodium bichromate results in decreased expression of BPHL mRNA | CTD | PMID:25993096 | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of BPHL mRNA | CTD | PMID:30047161 | sunitinib | decreases expression | ISO | BPHL (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of BPHL mRNA | CTD | PMID:31533062 | tebufenpyrad | decreases expression | ISO | BPHL (Homo sapiens) | 6480464 | 4-chloro-N-((4-(1 and 1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in decreased expression of BPHL mRNA | CTD | PMID:33512557 | temozolomide | increases expression | ISO | BPHL (Homo sapiens) | 6480464 | Temozolomide results in increased expression of BPHL mRNA | CTD | PMID:31758290 | tetrachloromethane | increases expression | ISO | Bphl (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of BPHL mRNA | CTD | PMID:17484886 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of BPHL mRNA | CTD | PMID:31150632 | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of BPHL mRNA] | CTD | PMID:31150632 | tetrachloromethane | decreases expression | ISO | Bphl (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of BPHL mRNA | CTD | PMID:27339419 and PMID:31919559 | thapsigargin | decreases expression | ISO | BPHL (Homo sapiens) | 6480464 | Thapsigargin results in decreased expression of BPHL mRNA | CTD | PMID:22378314 | thifluzamide | decreases expression | ISO | BPHL (Homo sapiens) | 6480464 | thifluzamide results in decreased expression of BPHL mRNA | CTD | PMID:33512557 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of BPHL mRNA | CTD | PMID:23411599 and PMID:34492290 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of BPHL mRNA | CTD | PMID:33387578 | trichostatin A | affects expression | ISO | BPHL (Homo sapiens) | 6480464 | trichostatin A affects the expression of BPHL mRNA | CTD | PMID:28542535 | triptonide | increases expression | ISO | Bphl (Mus musculus) | 6480464 | triptonide results in increased expression of BPHL mRNA | CTD | PMID:33045310 | trovafloxacin | decreases expression | ISO | Bphl (Mus musculus) | 6480464 | trovafloxacin results in decreased expression of BPHL mRNA | CTD | PMID:35537566 | tunicamycin | decreases expression | ISO | BPHL (Homo sapiens) | 6480464 | Tunicamycin results in decreased expression of BPHL mRNA | CTD | PMID:22378314 | valproic acid | increases methylation | ISO | BPHL (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of BPHL gene | CTD | PMID:29154799 | valproic acid | affects expression | ISO | BPHL (Homo sapiens) | 6480464 | Valproic Acid affects the expression of BPHL mRNA | CTD | PMID:25979313 | vancomycin | increases expression | ISO | Bphl (Mus musculus) | 6480464 | Vancomycin results in increased expression of BPHL mRNA | CTD | PMID:18930951 | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of BPHL mRNA | CTD | PMID:22615374 | |