Serpinb6a (serpin family B member 6A) - Rat Genome Database

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Gene: Serpinb6a (serpin family B member 6A) Rattus norvegicus
Analyze
Symbol: Serpinb6a
Name: serpin family B member 6A
RGD ID: 735108
Description: Predicted to enable protease binding activity and serine-type endopeptidase inhibitor activity. Predicted to be involved in cellular response to osmotic stress; negative regulation of endopeptidase activity; and sensory perception of sound. Predicted to be part of serine protease inhibitor complex. Predicted to be active in cytoplasm and extracellular space. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 91. Orthologous to human SERPINB6 (serpin family B member 6); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: MGC72983; serine (or cysteine) peptidase inhibitor, clade B, member 6; serine (or cysteine) peptidase inhibitor, clade B, member 6a; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 6; serpin B6; serpin family B member 6; serpin peptidase inhibitor, clade B (ovalbumin), member 6; Serpinb6
RGD Orthologs
Human
Mouse
Bonobo
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81731,076,811 - 31,195,035 (+)NCBIGRCr8
mRatBN7.21730,871,468 - 30,989,703 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1730,871,468 - 31,014,427 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1730,685,617 - 30,804,168 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01732,289,360 - 32,407,916 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01730,681,350 - 30,799,899 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01732,154,747 - 32,209,598 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1732,190,801 - 32,209,590 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01734,084,076 - 34,102,920 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41737,316,389 - 37,335,124 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11737,319,229 - 37,337,965 (+)NCBI
Celera1730,535,108 - 30,553,843 (+)NCBICelera
Cytogenetic Map17p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Serpinb6aRatautosomal recessive nonsyndromic deafness 91  ISOSERPINB6 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:17576681 more ...
Serpinb6aRatHearing Loss  ISOSERPINB6 (Homo sapiens)8554872ClinVar Annotator: match by term: Hearing impairmentClinVarPMID:30311386
Serpinb6aRatUsher syndrome  ISOSERPINB6 (Homo sapiens)8554872ClinVar Annotator: match by term: Usher syndromeClinVarPMID:24033266 more ...
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Serpinb6aRatWeight Gain  ISOSerpinb6a (Mus musculus)11554173CTD Direct Evidence: marker/mechanismCTDPMID:19030233
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Serpinb6aRatautosomal recessive nonsyndromic deafness 91  ISOSERPINB6 (Homo sapiens)7240710 OMIM 

1 to 20 of 121 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Serpinb6aRat(1->4)-beta-D-glucan multiple interactionsISOSerpinb6a (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of SERPINB6A mRNACTDPMID:36331819
Serpinb6aRat1,1-dichloroethene increases expressionISOSerpinb6a (Mus musculus)6480464vinylidene chloride results in increased expression of SERPINB6A mRNACTDPMID:26682919
Serpinb6aRat1,2-dimethylhydrazine decreases expressionISOSerpinb6a (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of SERPINB6A mRNACTDPMID:22206623
Serpinb6aRat17beta-hydroxy-5alpha-androstan-3-one decreases expressionISOSerpinb6a (Mus musculus)6480464Dihydrotestosterone results in decreased expression of SERPINB6A mRNACTDPMID:17023530
Serpinb6aRat2,2',4,4',5,5'-hexachlorobiphenyl multiple interactionsISOSerpinb6a (Mus musculus)64804642 more ...CTDPMID:21851831
Serpinb6aRat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOSerpinb6a (Mus musculus)64804642 more ...CTDPMID:21851831
Serpinb6aRat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOSERPINB6 (Homo sapiens)6480464Tetrachlorodibenzodioxin results in increased expression of SERPINB6 mRNACTDPMID:20106945
Serpinb6aRat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOSerpinb6a (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of SERPINB6A mRNACTDPMID:19770486 more ...
Serpinb6aRat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOSerpinb6a (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of SERPINB6A mRNACTDPMID:18343893 more ...
Serpinb6aRat2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of SERPINB6A mRNACTDPMID:22298810 and PMID:34747641
Serpinb6aRat2,3,7,8-Tetrachlorodibenzofuran affects expressionISOSerpinb6a (Mus musculus)64804642 more ...CTDPMID:18343893
Serpinb6aRat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of SERPINB6A mRNACTDPMID:21346803
Serpinb6aRat2,6-dimethoxyphenol multiple interactionsISOSERPINB6 (Homo sapiens)6480464[pyrogallol 1 more ...CTDPMID:38598786
Serpinb6aRat4,4'-sulfonyldiphenol increases expressionISOSerpinb6a (Mus musculus)6480464bisphenol S results in increased expression of SERPINB6A mRNACTDPMID:30951980
Serpinb6aRat4,4'-sulfonyldiphenol multiple interactionsEXP 6480464[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of SERPINB6A mRNACTDPMID:36041667
Serpinb6aRat4-hydroxyphenyl retinamide decreases expressionISOSerpinb6a (Mus musculus)6480464Fenretinide results in decreased expression of SERPINB6 mRNACTDPMID:28973697
Serpinb6aRat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of SERPINB6 mRNACTDPMID:30047161
Serpinb6aRatacetamide increases expressionEXP 6480464acetamide results in increased expression of SERPINB6A mRNACTDPMID:31881176
Serpinb6aRatactinomycin D multiple interactionsISOSERPINB6 (Homo sapiens)6480464[Dactinomycin co-treated with nutlin 3] results in increased secretion of SERPINB6 proteinCTDPMID:38460933
Serpinb6aRatAflatoxin B2 alpha decreases methylationISOSERPINB6 (Homo sapiens)6480464aflatoxin B2 results in decreased methylation of SERPINB6 intronCTDPMID:30157460

1 to 20 of 121 rows

Biological Process

  

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Serpinb6aRatcytoplasm is_active_inIBAMGI:103123 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Serpinb6aRatcytoplasm located_inISOSERPINB6 (Homo sapiens)1624291 PMID:14670919 more ...RGDPMID:14670919 more ...
Serpinb6aRatcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Serpinb6aRatcytoplasm located_inISOSerpinb6a (Mus musculus)1624291 PMID:17761692 and PMID:20451170RGDPMID:17761692 and PMID:20451170
Serpinb6aRatextracellular space located_inIEAInterPro:IPR0002151600115GO_REF:0000002InterProGO_REF:0000002
Serpinb6aRatextracellular space is_active_inIBAFB:FBgn0002930 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Serpinb6aRatnucleus NOT|located_inISOSERPINB6 (Homo sapiens)1624291 PMID:14670919RGDPMID:14670919
Serpinb6aRatserine protease inhibitor complex part_ofISOSERPINB6 (Homo sapiens)1624291 PMID:17761692RGDPMID:17761692

Molecular Function

  


#
Reference Title
Reference Citation
1. Cloning and molecular characterization of a human intracellular serine proteinase inhibitor. Coughlin P, etal., Proc Natl Acad Sci U S A 1993 Oct 15;90(20):9417-21.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
PMID:14670919   PMID:16175637   PMID:17761692   PMID:19056867   PMID:20451170   PMID:23376485   PMID:23533145   PMID:27068509  



Serpinb6a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81731,076,811 - 31,195,035 (+)NCBIGRCr8
mRatBN7.21730,871,468 - 30,989,703 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1730,871,468 - 31,014,427 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1730,685,617 - 30,804,168 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01732,289,360 - 32,407,916 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01730,681,350 - 30,799,899 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01732,154,747 - 32,209,598 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1732,190,801 - 32,209,590 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01734,084,076 - 34,102,920 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41737,316,389 - 37,335,124 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11737,319,229 - 37,337,965 (+)NCBI
Celera1730,535,108 - 30,553,843 (+)NCBICelera
Cytogenetic Map17p12NCBI
SERPINB6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3862,948,159 - 2,971,793 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl62,948,159 - 2,972,165 (-)EnsemblGRCh38hg38GRCh38
GRCh3762,948,393 - 2,972,027 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3662,893,392 - 2,917,089 (-)NCBINCBI36Build 36hg18NCBI36
Build 3462,893,391 - 2,917,089NCBI
Celera64,177,451 - 4,201,136 (-)NCBICelera
Cytogenetic Map6p25.2NCBI
HuRef62,821,595 - 2,845,591 (-)NCBIHuRef
CHM1_162,950,764 - 2,974,758 (-)NCBICHM1_1
T2T-CHM13v2.062,817,071 - 2,840,707 (-)NCBIT2T-CHM13v2.0
Serpinb6a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391334,101,901 - 34,186,777 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1334,101,901 - 34,186,777 (-)EnsemblGRCm39 Ensembl
GRCm381333,917,918 - 34,002,794 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1333,917,918 - 34,002,794 (-)EnsemblGRCm38mm10GRCm38
MGSCv371334,009,787 - 34,094,618 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361333,925,392 - 33,943,461 (-)NCBIMGSCv36mm8
Celera1335,047,258 - 35,132,241 (-)NCBICelera
Cytogenetic Map13A3.3NCBI
cM Map1314.0NCBI
HMSD
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21781,458,498 - 81,466,877 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11867,145,099 - 67,159,622 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01857,306,835 - 57,315,231 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11860,613,877 - 60,624,559 (+)NCBIpanpan1.1PanPan1.1panPan2
LOC106504299
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl71,752,689 - 1,776,087 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.171,755,252 - 1,776,144 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.271,832,151 - 1,836,133 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SERPINB6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11769,204,019 - 69,219,020 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1769,207,684 - 69,219,016 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660442,881,786 - 2,896,484 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

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Variants in Serpinb6a
751 total Variants


Assembly: mRatBN7.2

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain Variant Page
17 30915036 30915037 T A snv European Variation Archive Release 3, FXLE21/StmMcwi (2023), European Variation Archive Release 6, FXLE12/StmMcwi (2023), ACI/EurMcwi (2019), ACI/N (2020), BXH2/CubMcwi (2020), BXH3/CubMcwi (2020), DA/OlaHsd (2019), GK/FarMcwi (2019), HXB20/IpcvMcwi (2020), HXB2/IpcvMcwi (2019), HXB31/IpcvMcwi (2019), HXB4/IpcvMcwi (2020), LEW/Crl (2019), LEXF1A/Stm (2019), LEXF4/Stm (2020), LE/Stm (2019), MR/N (2020), MWF/Hsd (2019), PVG/Seac (2019), SHRSP/A3NCrl (2019), SHR/OlalpcvMcwi (2019), WAG/RijCrl (2020), WKY/NCrl (2019), WKY/N (2020), WN/N (2020), ACI/EurMcwi (2019NG), BDIX/NemOdaMcwi (2022), BUF/MnaMcwi (2022), DA/OlaHsd (2019NG), FXLE12/StmMcwi (2021), FXLE12/Stm (2019NG), FXLE13/Stm (2019NG), FXLE14/Stm (2019NG), FXLE17/Stm (2019NG), FXLE20/Stm (2019NG), FXLE26/Stm (2022), GK/FarMcwi (2019NG), HXB23/IpcvMcwi (2021), LEW/Crl (2019NG), LEXF7A/Stm (2019NG), LEXF7B/StmMcwi (2022), LEXF7C/StmMcwi (2022), LEXF8D/Stm (2022), LEXF9/StmMcwi (2022), MR/NRrrc (2022), MWF/SimwMcwi (2019NG), MWF/SimwMcwi (2019), RCS/LavRrrcMcwi (2021), SHRSP/A3NCrl (2019NG), SHR/NCrl (2021), SHR/NHsd (2021), SHR/NHsd (2021), SHR/OlalpcvMcwi (2019NG), WKY/NCrl (2019NG), FXLE26/StmMcwi (2023), FXLE13/StmMcwi (2023), FXLE22/StmMcwi (2023), FXLE20/StmMcwi (2023), LEXF8D/StmMcwi (2023), FXLE17/StmMcwi (2023), FXLE14/StmMcwi (2023), European Variation Archive Release 4 View more Information

Predicted Target Of
Summary Value
Count of predictions:88
Count of miRNA genes:80
Interacting mature miRNAs:85
Transcripts:ENSRNOT00000024161
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 41 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
2300002Iddm36Insulin dependent diabetes mellitus QTL 361.98blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)17999128640540197Rat
1354640Scl32Serum cholesterol level QTL 325.4blood HDL cholesterol amount (VT:0000184)blood high density lipoprotein cholesterol level (CMO:0000052)171578159260781592Rat
152023626Bp403Blood pressure QTL 4033.86arterial blood pressure trait (VT:2000000)172393042179524188Rat
1300123Bp194Blood pressure QTL 1942.82arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)17211514934551001Rat
9590107Sffal7Serum free fatty acids level QTL 74.810.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)172840914773409147Rat
2302377Scl61Serum cholesterol level QTL 614.36blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)172738994653481766Rat
70157Niddm32Non-insulin dependent diabetes mellitus QTL 324.34blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)172245492450909196Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
1354628Stl13Serum triglyceride level QTL 133.8blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)172129303960781592Rat

1 to 10 of 41 rows
RH129867  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21730,989,458 - 30,989,648 (+)MAPPERmRatBN7.2
Rnor_6.01732,209,354 - 32,209,543NCBIRnor6.0
Rnor_5.01734,102,676 - 34,102,865UniSTSRnor5.0
RGSC_v3.41737,334,888 - 37,335,077UniSTSRGSC3.4
Celera1730,553,607 - 30,553,796UniSTS
RH 3.4 Map17326.02UniSTS
Cytogenetic Map17p12UniSTS
Serpinb6  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2831,874,506 - 31,875,418 (+)MAPPERmRatBN7.2
Rnor_6.0834,714,297 - 34,715,208NCBIRnor6.0
Rnor_5.0834,745,725 - 34,746,636UniSTSRnor5.0
RGSC_v3.4833,282,598 - 33,283,509UniSTSRGSC3.4
Celera833,306,736 - 33,307,646UniSTS
Cytogenetic Map8q21UniSTS
Cytogenetic Map17p12UniSTS
Serpinb6c  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21730,978,000 - 30,978,060 (+)MAPPERmRatBN7.2
Rnor_6.01732,197,843 - 32,197,902NCBIRnor6.0
Rnor_5.01734,091,165 - 34,091,224UniSTSRnor5.0
RGSC_v3.41737,323,431 - 37,323,490UniSTSRGSC3.4
RGSC_v3.41737,826,272 - 37,826,332UniSTSRGSC3.4
Celera1731,029,328 - 31,029,388UniSTS
Celera1730,542,150 - 30,542,209UniSTS
Cytogenetic Map17p12UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000024161   ⟹   ENSRNOP00000024161
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1730,970,957 - 30,989,694 (+)Ensembl
Rnor_6.0 Ensembl1732,190,801 - 32,209,590 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000102782   ⟹   ENSRNOP00000089104
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1730,970,845 - 31,014,427 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000118879   ⟹   ENSRNOP00000090303
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1730,871,468 - 30,989,694 (+)Ensembl
RefSeq Acc Id: NM_001395026   ⟹   NP_001381955
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81731,076,811 - 31,195,035 (+)NCBI
mRatBN7.21730,871,468 - 30,989,697 (+)NCBI
RefSeq Acc Id: NM_001395027   ⟹   NP_001381956
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81731,176,255 - 31,195,035 (+)NCBI
mRatBN7.21730,970,915 - 30,989,697 (+)NCBI
RefSeq Acc Id: NM_199085   ⟹   NP_954516
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81731,176,255 - 31,195,035 (+)NCBI
mRatBN7.21730,970,915 - 30,989,697 (+)NCBI
Rnor_6.01732,190,801 - 32,209,590 (+)NCBI
Rnor_5.01734,084,076 - 34,102,920 (+)NCBI
RGSC_v3.41737,316,389 - 37,335,124 (+)RGD
Celera1730,535,108 - 30,553,843 (+)RGD
Sequence:
RefSeq Acc Id: XM_006253871   ⟹   XP_006253933
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81731,176,550 - 31,195,035 (+)NCBI
mRatBN7.21730,971,210 - 30,989,703 (+)NCBI
Rnor_6.01732,190,911 - 32,209,598 (+)NCBI
Rnor_5.01734,084,076 - 34,102,920 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039095492   ⟹   XP_038951420
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81731,076,961 - 31,195,035 (+)NCBI
mRatBN7.21730,871,622 - 30,989,697 (+)NCBI
RefSeq Acc Id: NP_954516   ⟸   NM_199085
- UniProtKB: Q6P9U0 (UniProtKB/TrEMBL),   A6J7I2 (UniProtKB/TrEMBL),   F7EUC3 (UniProtKB/TrEMBL),   A0A8I6ABJ3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006253933   ⟸   XM_006253871
- Peptide Label: isoform X2
- UniProtKB: A0A8I6A6H8 (UniProtKB/TrEMBL),   F7EUC3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000024161   ⟸   ENSRNOT00000024161
RefSeq Acc Id: XP_038951420   ⟸   XM_039095492
- Peptide Label: isoform X1
- UniProtKB: Q6P9U0 (UniProtKB/TrEMBL),   A6J7I2 (UniProtKB/TrEMBL),   F7EUC3 (UniProtKB/TrEMBL),   A0A8I6ABJ3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000089104   ⟸   ENSRNOT00000102782
SERPIN

Name Modeler Protein Id AA Range Protein Structure
AF-Q6P9U0-F1-model_v2 AlphaFold Q6P9U0 1-379 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13700417
Promoter ID:EPDNEW_R10941
Type:multiple initiation site
Name:Serpinb6a_1
Description:serpin family B member 6A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01732,190,802 - 32,190,862EPDNEW


1 to 32 of 32 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-9597 BioCyc
Ensembl Genes ENSRNOG00000017962 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000024161.6 UniProtKB/TrEMBL
  ENSRNOT00000102782 ENTREZGENE
  ENSRNOT00000102782.1 UniProtKB/TrEMBL
  ENSRNOT00000118879 ENTREZGENE
  ENSRNOT00000118879.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.39.10 UniProtKB/TrEMBL
  3.30.497.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:6887824 IMAGE-MGC_LOAD
InterPro Protease_inhib_I4_serpin UniProtKB/TrEMBL
  Protease_inhib_I4_serpin_CS UniProtKB/TrEMBL
  Sepin_dom UniProtKB/TrEMBL
  Serpin_sf UniProtKB/TrEMBL
  Serpin_sf_1 UniProtKB/TrEMBL
  Serpin_sf_2 UniProtKB/TrEMBL
MGC_CLONE MGC:72983 IMAGE-MGC_LOAD
NCBI Gene 291085 ENTREZGENE
PANTHER Prot_inh_serpin UniProtKB/TrEMBL
  SERPIN B6 UniProtKB/TrEMBL
Pfam Serpin UniProtKB/TrEMBL
PhenoGen Serpinb6a PhenoGen
PROSITE SERPIN UniProtKB/TrEMBL
RatGTEx ENSRNOG00000017962 RatGTEx
SMART SERPIN UniProtKB/TrEMBL
Superfamily-SCOP Prot_inh_serpin UniProtKB/TrEMBL
UniProt A0A8I6A6H8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ABJ3 ENTREZGENE, UniProtKB/TrEMBL
  A6J7I2 ENTREZGENE, UniProtKB/TrEMBL
  F7EUC3 ENTREZGENE, UniProtKB/TrEMBL
  Q6P9U0 ENTREZGENE
UniProt Secondary Q6P9U0 UniProtKB/TrEMBL
1 to 32 of 32 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-06-19 Serpinb6a  serpin family B member 6A  Serpinb6  serpin family B member 6  Name and Symbol changed 629549 APPROVED
2016-04-13 Serpinb6  serpin family B member 6  Serpinb6  serpin peptidase inhibitor, clade B (ovalbumin), member 6  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-02-02 Serpinb6  serpin peptidase inhibitor, clade B (ovalbumin), member 6  Serpinb6a  serine (or cysteine) peptidase inhibitor, clade B, member 6a  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Serpinb6a  serine (or cysteine) peptidase inhibitor, clade B, member 6a  Serpinb6  serine (or cysteine) peptidase inhibitor, clade B, member 6  Symbol and Name updated 1299863 APPROVED
2005-07-08 Serpinb6  serine (or cysteine) peptidase inhibitor, clade B, member 6    serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 6  Name updated 1299863 APPROVED