Elmo1 (engulfment and cell motility 1) - Rat Genome Database

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Gene: Elmo1 (engulfment and cell motility 1) Rattus norvegicus
Analyze
Symbol: Elmo1
Name: engulfment and cell motility 1
RGD ID: 1308182
Description: Predicted to enable SH3 domain binding activity. Predicted to contribute to guanyl-nucleotide exchange factor activity. Involved in regulation of postsynapse assembly. Is active in glutamatergic synapse and postsynapse. Orthologous to human ELMO1 (engulfment and cell motility 1); PARTICIPATES IN chemokine mediated signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; alpha-Zearalanol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ELMO1s; engulfment and cell motility 1 splice 1; engulfment and cell motility 1, ced-12 homolog; engulfment and cell motility 1, ced-12 homolog (C. elegans); engulfment and cell motility protein 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81748,982,188 - 49,518,525 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1748,982,188 - 49,518,159 (-)EnsemblGRCr8
mRatBN7.21744,286,495 - 44,822,668 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1744,286,485 - 44,822,788 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1746,357,453 - 46,881,045 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01751,116,592 - 51,640,189 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01745,608,016 - 46,130,585 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01746,352,102 - 46,888,788 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1746,353,330 - 46,794,845 (-)Ensemblrn6Rnor6.0
Rnor_5.01756,598,697 - 57,133,816 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41751,989,458 - 52,552,704 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1751,701,962 - 52,225,665 (+)NCBICelera
RGSC_v3.11751,992,297 - 52,462,470 (-)NCBI
Cytogenetic Map17q11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
acetamide  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
amitrole  (EXP)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
carmustine  (ISO)
CGP 52608  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
cocaine  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dorsomorphin  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
fragrance  (ISO)
fulvestrant  (ISO)
glycidol  (EXP)
methyl methanesulfonate  (ISO)
O-methyleugenol  (ISO)
ozone  (ISO)
paracetamol  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pinostrobin  (ISO)
pirinixic acid  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
staurosporine  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
tetrachloromethane  (EXP)
thimerosal  (ISO)
titanium dioxide  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. The RhoG/ELMO1/Dock180 signaling module is required for spine morphogenesis in hippocampal neurons. Kim JY, etal., J Biol Chem. 2011 Oct 28;286(43):37615-24. doi: 10.1074/jbc.M111.268029. Epub 2011 Sep 7.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11595183   PMID:12029088   PMID:12134158   PMID:12879077   PMID:17021600   PMID:19946888   PMID:26993296   PMID:29615491  


Genomics

Comparative Map Data
Elmo1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81748,982,188 - 49,518,525 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1748,982,188 - 49,518,159 (-)EnsemblGRCr8
mRatBN7.21744,286,495 - 44,822,668 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1744,286,485 - 44,822,788 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1746,357,453 - 46,881,045 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01751,116,592 - 51,640,189 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01745,608,016 - 46,130,585 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01746,352,102 - 46,888,788 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1746,353,330 - 46,794,845 (-)Ensemblrn6Rnor6.0
Rnor_5.01756,598,697 - 57,133,816 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41751,989,458 - 52,552,704 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1751,701,962 - 52,225,665 (+)NCBICelera
RGSC_v3.11751,992,297 - 52,462,470 (-)NCBI
Cytogenetic Map17q11NCBI
ELMO1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38736,852,906 - 37,449,326 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl736,852,906 - 37,449,223 (-)Ensemblhg38GRCh38
GRCh37736,892,511 - 37,488,929 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36736,860,486 - 37,455,036 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34736,667,206 - 36,798,961NCBI
Celera736,878,399 - 37,472,945 (-)NCBICelera
Cytogenetic Map7p14.2-p14.1NCBI
HuRef736,771,444 - 37,368,496 (-)NCBIHuRef
CHM1_1736,891,996 - 37,488,280 (-)NCBICHM1_1
T2T-CHM13v2.0736,993,255 - 37,589,754 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2736,930,165 - 37,526,532 (-)NCBI
Elmo1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391320,274,677 - 20,792,523 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1320,274,766 - 20,792,523 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381320,090,507 - 20,608,353 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1320,090,596 - 20,608,353 (+)Ensemblmm10GRCm38
MGSCv371320,277,294 - 20,698,394 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361320,192,890 - 20,613,990 (+)NCBIMGSCv36mm8
Celera1320,478,055 - 20,898,552 (+)NCBICelera
Cytogenetic Map13A2NCBI
cM Map137.21NCBI
Elmo1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554606,044,725 - 6,581,269 (+)Ensembl
ChiLan1.0NW_0049554606,044,827 - 6,580,770 (+)NCBIChiLan1.0ChiLan1.0
ELMO1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2641,692,166 - 42,283,854 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1790,016,901 - 90,608,596 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0737,493,854 - 38,085,555 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1737,720,589 - 38,310,917 (-)NCBIPanPan1.1PanPan1.1panPan2
ELMO1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11448,163,218 - 48,610,626 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1448,164,049 - 48,730,248 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1447,606,767 - 48,132,630 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01448,104,763 - 48,631,432 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1448,104,765 - 48,631,965 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11448,210,909 - 48,736,343 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01447,890,268 - 48,416,690 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01448,267,197 - 48,792,889 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Elmo1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511893,096,524 - 93,647,112 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647812,306,450 - 12,754,963 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647812,308,255 - 12,754,957 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ELMO1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1836,786,378 - 37,347,283 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11836,755,026 - 37,336,095 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21840,536,457 - 40,984,221 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ELMO1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12121,066,910 - 21,639,149 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2121,066,924 - 21,640,705 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666062694,803 - 1,273,767 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Elmo1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474023,881,197 - 24,353,526 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474023,776,788 - 24,354,682 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Elmo1
2560 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:228
Count of miRNA genes:156
Interacting mature miRNAs:194
Transcripts:ENSRNOT00000025516, ENSRNOT00000074910
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631497Bp98Blood pressure QTL 983.66arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)174135465160463643Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
1358295Aocep1Aortic cell protein QTL 16.17e-07thoracic aorta cellular protein amount (VT:0010598)aortic cell percentage174099000585990005Rat
1354640Scl32Serum cholesterol level QTL 325.4blood HDL cholesterol amount (VT:0000184)blood high density lipoprotein cholesterol level (CMO:0000052)171578159260781592Rat
152023626Bp403Blood pressure QTL 4033.86arterial blood pressure trait (VT:2000000)172393042179524188Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)173747984782479847Rat
9590107Sffal7Serum free fatty acids level QTL 74.810.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)172840914773409147Rat
2302377Scl61Serum cholesterol level QTL 614.36blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)172738994653481766Rat
70157Niddm32Non-insulin dependent diabetes mellitus QTL 324.34blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)172245492450909196Rat
724549Niddm56Non-insulin dependent diabetes mellitus QTL 560.03blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)173199078476990784Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
1598871Memor5Memory QTL 55.3exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)174054004180387013Rat
1354628Stl13Serum triglyceride level QTL 133.8blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)172129303960781592Rat
1581512Cm55Cardiac mass QTL 552.80.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172702794956836890Rat
10054088Scort28Serum corticosterone level QTL 282.040.0102blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17452803849528038Rat
1354630Cm34Cardiac mass QTL 348.7heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)17429913069599340Rat
61394Bp8Blood pressure QTL 82.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172308056759555013Rat
1559055Bp278Blood pressure QTL 2780.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318468653184Rat
10450503Bp386Blood pressure QTL 3860.28arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)173136839162109574Rat
152025238Slep14Serum leptin concentration QTL 144.62blood leptin amount (VT:0005667)172418489079524188Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)17429913069599340Rat
2313854Bp343Blood pressure QTL 3433.9life span trait (VT:0005372)age at time of death (CMO:0001193)173199078450909196Rat
2317054Aia12Adjuvant induced arthritis QTL 124.24joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)173828150983281509Rat
1354635Bp245Blood pressure QTL 2456arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)174207316069599340Rat
1331765Hrtrt15Heart rate QTL 154.094heart pumping trait (VT:2000009)heart rate (CMO:0000002)171533061355836425Rat
8552928Pigfal9Plasma insulin-like growth factor 1 level QTL 99blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)172840914773409147Rat
1300148Bp192Blood pressure QTL 1923.47arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)173455084373951021Rat
2317060Aia26Adjuvant induced arthritis QTL 263.22joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)173828150983281509Rat
2303627Vencon8Ventilatory control QTL 80.001respiration trait (VT:0001943)tidal volume (CMO:0000222)17452803849528038Rat
12903980Cm120Cardiac mass QTL 1200.002heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)172365318468653184Rat
12903981Am17Aortic mass QTL 170.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)172365318468653184Rat
4889955Bss93Bone structure and strength QTL 934.4tibia size trait (VT:0100001)tibia cortical bone volume to tibia total bone volume ratio (CMO:0001727)172702794960463643Rat
2303561Bw91Body weight QTL 912body mass (VT:0001259)body weight (CMO:0000012)17886846253868462Rat
12903982Kidm70Kidney mass QTL 700.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)172365318470974005Rat
12903978Cm118Cardiac mass QTL 1180.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)172365318468653184Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)173136839173951021Rat
12903979Cm119Cardiac mass QTL 1190.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172365318468653184Rat
1354619Bp242Blood pressure QTL 2426.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172459934069599340Rat
1354596Bw32Body weight QTL 324.5body mass (VT:0001259)body weight (CMO:0000012)17429913060781592Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat
152023740Bp406Blood pressure QTL 4066.06arterial blood pressure trait (VT:2000000)172393042179524188Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173199078481292925Rat
7488966Bp370Blood pressure QTL 3700.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318457246843Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17160781592Rat
152023737Bp405Blood pressure QTL 4055.06arterial blood pressure trait (VT:2000000)2393042179524188Rat
1354659Scl68Serum cholesterol level QTL 683.9blood VLDL cholesterol amount (VT:0005144)blood very low density lipoprotein cholesterol level (CMO:0000648)171578159260781592Rat
152023736Bp404Blood pressure QTL 4043.78arterial blood pressure trait (VT:2000000)172393042179524188Rat
724528Uae4Urinary albumin excretion QTL 44.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)173583708569599340Rat

Markers in Region
D17Got55  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81749,447,887 - 49,448,079 (+)Marker Load Pipeline
mRatBN7.21744,752,205 - 44,752,397 (+)MAPPERmRatBN7.2
Rnor_6.01746,818,168 - 46,818,357NCBIRnor6.0
Rnor_5.01756,669,308 - 56,669,497UniSTSRnor5.0
RGSC_v3.41752,482,956 - 52,483,145UniSTSRGSC3.4
RGSC_v3.41752,482,955 - 52,483,145RGDRGSC3.4
Celera1751,771,145 - 51,771,334UniSTS
RGSC_v3.11752,485,796 - 52,485,986RGD
Cytogenetic Map17q11UniSTS
RH138831  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81749,479,883 - 49,480,074 (+)Marker Load Pipeline
mRatBN7.21744,784,201 - 44,784,392 (+)MAPPERmRatBN7.2
Rnor_6.01746,850,166 - 46,850,356NCBIRnor6.0
Rnor_5.01756,637,129 - 56,637,319UniSTSRnor5.0
RGSC_v3.41752,514,118 - 52,514,308UniSTSRGSC3.4
Celera1751,740,137 - 51,740,327UniSTS
Cytogenetic Map17q11UniSTS
WI-16086  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21744,286,511 - 44,286,664 (+)MAPPERmRatBN7.2
Rnor_6.01746,352,113 - 46,352,265NCBIRnor6.0
Rnor_5.01757,133,653 - 57,133,805UniSTSRnor5.0
RGSC_v3.41751,989,468 - 51,989,620UniSTSRGSC3.4
Celera1752,225,503 - 52,225,655UniSTS
Cytogenetic Map17q11UniSTS
RH142856  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21744,818,227 - 44,818,381 (+)MAPPERmRatBN7.2
Rnor_6.01746,884,228 - 46,884,381NCBIRnor6.0
Rnor_5.01756,603,104 - 56,603,257UniSTSRnor5.0
RGSC_v3.41752,548,144 - 52,548,297UniSTSRGSC3.4
Celera1751,706,369 - 51,706,522UniSTS
Cytogenetic Map17q11UniSTS
GDB:4585326  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21744,705,591 - 44,706,652 (+)MAPPERmRatBN7.2
Rnor_6.01746,771,479 - 46,772,539NCBIRnor6.0
Rnor_5.01756,714,821 - 56,715,881UniSTSRnor5.0
RGSC_v3.41752,436,190 - 52,437,250UniSTSRGSC3.4
Celera1751,816,946 - 51,818,006UniSTS
Cytogenetic Map17q11UniSTS
fc31d07.x1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.01756,607,463 - 56,608,944UniSTSRnor5.0
Celera1751,710,722 - 51,712,203UniSTS
Cytogenetic Map17q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 355 192 11 144 80 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001395578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600613 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276614 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276615 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010058900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ438489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000077910   ⟹   ENSRNOP00000073656
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1748,982,565 - 49,518,159 (-)Ensembl
mRatBN7.2 Ensembl1744,549,852 - 44,822,788 (-)Ensembl
Rnor_6.0 Ensembl1746,353,330 - 46,794,845 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000078331   ⟹   ENSRNOP00000073154
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1749,017,704 - 49,518,159 (-)Ensembl
mRatBN7.2 Ensembl1744,322,014 - 44,822,788 (-)Ensembl
Rnor_6.0 Ensembl1746,387,560 - 46,794,845 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000090663   ⟹   ENSRNOP00000073757
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1748,982,188 - 49,518,159 (-)Ensembl
mRatBN7.2 Ensembl1744,286,485 - 44,822,788 (-)Ensembl
Rnor_6.0 Ensembl1746,353,330 - 46,794,845 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000129149   ⟹   ENSRNOP00000109172
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1748,982,188 - 49,397,883 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000167945   ⟹   ENSRNOP00000104986
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1748,982,188 - 49,518,159 (-)Ensembl
RefSeq Acc Id: NM_001395578   ⟹   NP_001382507
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81748,982,188 - 49,518,159 (-)NCBI
mRatBN7.21744,286,496 - 44,822,477 (-)NCBI
RefSeq Acc Id: XM_063276609   ⟹   XP_063132679
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81748,982,193 - 49,518,116 (-)NCBI
RefSeq Acc Id: XM_063276610   ⟹   XP_063132680
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81748,982,193 - 49,518,480 (-)NCBI
RefSeq Acc Id: XM_063276611   ⟹   XP_063132681
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81748,982,193 - 49,518,120 (-)NCBI
RefSeq Acc Id: XM_063276612   ⟹   XP_063132682
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81748,982,193 - 49,425,086 (-)NCBI
RefSeq Acc Id: XM_063276614   ⟹   XP_063132684
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81748,982,193 - 49,425,095 (-)NCBI
RefSeq Acc Id: XM_063276615   ⟹   XP_063132685
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81748,982,193 - 49,518,525 (-)NCBI
RefSeq Acc Id: XM_063276616   ⟹   XP_063132686
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81748,982,193 - 49,518,120 (-)NCBI
RefSeq Acc Id: XR_010058900
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81749,034,564 - 49,518,446 (-)NCBI
Ensembl Acc Id: ENSRNOP00000073757   ⟸   ENSRNOT00000090663
Ensembl Acc Id: ENSRNOP00000073656   ⟸   ENSRNOT00000077910
Ensembl Acc Id: ENSRNOP00000073154   ⟸   ENSRNOT00000078331
RefSeq Acc Id: NP_001382507   ⟸   NM_001395578
- UniProtKB: A6KN57 (UniProtKB/TrEMBL),   D3ZY46 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132685   ⟸   XM_063276615
- Peptide Label: isoform X2
- UniProtKB: D3ZY46 (UniProtKB/TrEMBL),   A6KN57 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132680   ⟸   XM_063276610
- Peptide Label: isoform X1
- UniProtKB: D3ZY46 (UniProtKB/TrEMBL),   G8CYZ7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132686   ⟸   XM_063276616
- Peptide Label: isoform X2
- UniProtKB: D3ZY46 (UniProtKB/TrEMBL),   A6KN57 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132681   ⟸   XM_063276611
- Peptide Label: isoform X1
- UniProtKB: D3ZY46 (UniProtKB/TrEMBL),   G8CYZ7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132679   ⟸   XM_063276609
- Peptide Label: isoform X1
- UniProtKB: D3ZY46 (UniProtKB/TrEMBL),   G8CYZ7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132684   ⟸   XM_063276614
- Peptide Label: isoform X2
- UniProtKB: D3ZY46 (UniProtKB/TrEMBL),   A6KN57 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132682   ⟸   XM_063276612
- Peptide Label: isoform X1
- UniProtKB: D3ZY46 (UniProtKB/TrEMBL),   G8CYZ7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000104986   ⟸   ENSRNOT00000167945
Ensembl Acc Id: ENSRNOP00000109172   ⟸   ENSRNOT00000129149
Protein Domains
ELMO   PH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G8CYZ7-F1-model_v2 AlphaFold G8CYZ7 1-742 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700506
Promoter ID:EPDNEW_R11022
Type:single initiation site
Name:Elmo1_1
Description:engulfment and cell motility 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01746,794,930 - 46,794,990EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308182 AgrOrtholog
BioCyc Gene G2FUF-9157 BioCyc
Ensembl Genes ENSRNOG00000059705 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000077910.2 UniProtKB/TrEMBL
  ENSRNOT00000078331.2 UniProtKB/TrEMBL
  ENSRNOT00000090663 ENTREZGENE
  ENSRNOT00000090663.2 UniProtKB/TrEMBL
  ENSRNOT00000129149 ENTREZGENE
  ENSRNOT00000167945 ENTREZGENE
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  6.10.250.810 UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  DUF3361 UniProtKB/TrEMBL
  ELMO_domain-containing UniProtKB/TrEMBL
  Engulfment_cell_motility_ELMO UniProtKB/TrEMBL
  PH_type UniProtKB/TrEMBL
  Pleckstrin_homology UniProtKB/TrEMBL
NCBI Gene 361251 ENTREZGENE
PANTHER ENGULFMENT AND CELL MOTILITY UniProtKB/TrEMBL
  PTHR12771:SF23 UniProtKB/TrEMBL
Pfam DUF3361 UniProtKB/TrEMBL
  ELMO_CED12 UniProtKB/TrEMBL
  PH_12 UniProtKB/TrEMBL
PhenoGen Elmo1 PhenoGen
PROSITE ELMO UniProtKB/TrEMBL
RatGTEx ENSRNOG00000059705 RatGTEx
Superfamily-SCOP ARM-type_fold UniProtKB/TrEMBL
  PH domain-like UniProtKB/TrEMBL
UniProt A0A0G2K4S6_RAT UniProtKB/TrEMBL
  A0A0G2K633_RAT UniProtKB/TrEMBL
  A6KN57 ENTREZGENE, UniProtKB/TrEMBL
  A6KN59_RAT UniProtKB/TrEMBL
  D3ZY46 ENTREZGENE, UniProtKB/TrEMBL
  G8CYZ7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-28 Elmo1  engulfment and cell motility 1  Elmo1  engulfment and cell motility 1, ced-12 homolog (C. elegans)   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Elmo1  engulfment and cell motility 1, ced-12 homolog (C. elegans)   Elmo1_predicted  engulfment and cell motility 1, ced-12 homolog (C. elegans) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Elmo1_predicted  engulfment and cell motility 1, ced-12 homolog (C. elegans) (predicted)      Symbol and Name status set to approved 70820 APPROVED