Elmo1 (engulfment and cell motility 1) - Rat Genome Database

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Gene: Elmo1 (engulfment and cell motility 1) Rattus norvegicus
Analyze
Symbol: Elmo1
Name: engulfment and cell motility 1
RGD ID: 1308182
Description: Predicted to enable SH3 domain binding activity. Predicted to contribute to guanyl-nucleotide exchange factor activity. Predicted to be involved in several processes, including Rac protein signal transduction; actin filament organization; and phagocytosis, engulfment. Predicted to act upstream of or within actin filament-based process and phagocytosis. Predicted to be located in cytoplasm. Predicted to be part of guanyl-nucleotide exchange factor complex. Predicted to be active in plasma membrane. Orthologous to human ELMO1 (engulfment and cell motility 1); PARTICIPATES IN chemokine mediated signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ELMO1s; engulfment and cell motility 1 splice 1; engulfment and cell motility 1, ced-12 homolog; engulfment and cell motility 1, ced-12 homolog (C. elegans) ; engulfment and cell motility protein 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21744,286,495 - 44,822,788 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1744,286,485 - 44,822,788 (-)Ensembl
Rnor_6.01746,352,102 - 46,888,788 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1746,353,330 - 46,794,845 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01756,598,697 - 57,133,816 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41751,989,458 - 52,552,704 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11751,992,297 - 52,462,470 (-)NCBI
Celera1751,701,962 - 52,225,665 (+)NCBICelera
Cytogenetic Map17q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11595183   PMID:12029088   PMID:12134158   PMID:12879077   PMID:17021600   PMID:19946888   PMID:21900250   PMID:26993296   PMID:29615491  


Genomics

Comparative Map Data
Elmo1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21744,286,495 - 44,822,788 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1744,286,485 - 44,822,788 (-)Ensembl
Rnor_6.01746,352,102 - 46,888,788 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1746,353,330 - 46,794,845 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01756,598,697 - 57,133,816 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41751,989,458 - 52,552,704 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11751,992,297 - 52,462,470 (-)NCBI
Celera1751,701,962 - 52,225,665 (+)NCBICelera
Cytogenetic Map17q11NCBI
ELMO1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38736,852,906 - 37,449,326 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl736,852,906 - 37,449,223 (-)EnsemblGRCh38hg38GRCh38
GRCh37736,892,511 - 37,488,929 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36736,860,486 - 37,455,036 (-)NCBINCBI36hg18NCBI36
Build 34736,667,206 - 36,798,961NCBI
Celera736,878,399 - 37,472,945 (-)NCBI
Cytogenetic Map7p14.2-p14.1NCBI
HuRef736,771,444 - 37,368,496 (-)NCBIHuRef
CHM1_1736,891,996 - 37,488,280 (-)NCBICHM1_1
T2T-CHM13v2.0736,993,255 - 37,589,754 (-)NCBI
CRA_TCAGchr7v2736,930,165 - 37,526,532 (-)NCBI
Elmo1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391320,274,677 - 20,792,523 (+)NCBIGRCm39mm39
GRCm39 Ensembl1320,274,766 - 20,792,523 (+)Ensembl
GRCm381320,090,507 - 20,608,353 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1320,090,596 - 20,608,353 (+)EnsemblGRCm38mm10GRCm38
MGSCv371320,277,294 - 20,698,394 (+)NCBIGRCm37mm9NCBIm37
MGSCv361320,192,890 - 20,613,990 (+)NCBImm8
Celera1320,478,055 - 20,898,552 (+)NCBICelera
Cytogenetic Map13A2NCBI
Elmo1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554606,044,725 - 6,581,269 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554606,044,827 - 6,580,770 (+)NCBIChiLan1.0ChiLan1.0
ELMO1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1737,720,589 - 38,310,917 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v0737,493,854 - 38,085,555 (-)NCBIMhudiblu_PPA_v0panPan3
ELMO1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11448,163,218 - 48,610,626 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1448,164,049 - 48,730,248 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1447,606,767 - 48,132,630 (-)NCBI
ROS_Cfam_1.01448,104,763 - 48,631,432 (-)NCBI
ROS_Cfam_1.0 Ensembl1448,104,765 - 48,631,965 (-)Ensembl
UMICH_Zoey_3.11448,210,909 - 48,736,343 (-)NCBI
UNSW_CanFamBas_1.01447,890,268 - 48,416,690 (-)NCBI
UU_Cfam_GSD_1.01448,267,197 - 48,792,889 (-)NCBI
Elmo1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511893,096,524 - 93,647,112 (-)NCBI
SpeTri2.0NW_00493647812,308,255 - 12,754,957 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ELMO1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1836,786,378 - 37,347,283 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11836,755,026 - 37,336,095 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21840,536,457 - 40,984,221 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ELMO1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12121,066,910 - 21,639,149 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2121,066,924 - 21,640,705 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666062694,803 - 1,273,767 (-)NCBIVero_WHO_p1.0
Elmo1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474023,881,197 - 24,353,526 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462474023,776,788 - 24,354,682 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
D17Got55  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21744,752,205 - 44,752,397 (+)MAPPERmRatBN7.2
Rnor_6.01746,818,168 - 46,818,357NCBIRnor6.0
Rnor_5.01756,669,308 - 56,669,497UniSTSRnor5.0
RGSC_v3.41752,482,955 - 52,483,145RGDRGSC3.4
RGSC_v3.41752,482,956 - 52,483,145UniSTSRGSC3.4
RGSC_v3.11752,485,796 - 52,485,986RGD
Celera1751,771,145 - 51,771,334UniSTS
Cytogenetic Map17q11UniSTS
RH138831  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21744,784,201 - 44,784,392 (+)MAPPERmRatBN7.2
Rnor_6.01746,850,166 - 46,850,356NCBIRnor6.0
Rnor_5.01756,637,129 - 56,637,319UniSTSRnor5.0
RGSC_v3.41752,514,118 - 52,514,308UniSTSRGSC3.4
Celera1751,740,137 - 51,740,327UniSTS
Cytogenetic Map17q11UniSTS
WI-16086  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21744,286,511 - 44,286,664 (+)MAPPERmRatBN7.2
Rnor_6.01746,352,113 - 46,352,265NCBIRnor6.0
Rnor_5.01757,133,653 - 57,133,805UniSTSRnor5.0
RGSC_v3.41751,989,468 - 51,989,620UniSTSRGSC3.4
Celera1752,225,503 - 52,225,655UniSTS
Cytogenetic Map17q11UniSTS
RH142856  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21744,818,227 - 44,818,381 (+)MAPPERmRatBN7.2
Rnor_6.01746,884,228 - 46,884,381NCBIRnor6.0
Rnor_5.01756,603,104 - 56,603,257UniSTSRnor5.0
RGSC_v3.41752,548,144 - 52,548,297UniSTSRGSC3.4
Celera1751,706,369 - 51,706,522UniSTS
Cytogenetic Map17q11UniSTS
GDB:4585326  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21744,705,591 - 44,706,652 (+)MAPPERmRatBN7.2
Rnor_6.01746,771,479 - 46,772,539NCBIRnor6.0
Rnor_5.01756,714,821 - 56,715,881UniSTSRnor5.0
RGSC_v3.41752,436,190 - 52,437,250UniSTSRGSC3.4
Celera1751,816,946 - 51,818,006UniSTS
Cytogenetic Map17q11UniSTS
fc31d07.x1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.01756,607,463 - 56,608,944UniSTSRnor5.0
Celera1751,710,722 - 51,712,203UniSTS
Cytogenetic Map17q11UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590107Sffal7Serum free fatty acids level QTL 74.810.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)172840914773409147Rat
1354630Cm34Cardiac mass QTL 348.7heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)17429913069599340Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
1354635Bp245Blood pressure QTL 2456arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)174207316069599340Rat
12903978Cm118Cardiac mass QTL 1180.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)172365318468653184Rat
631497Bp98Blood pressure QTL 983.66arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)174135465160463643Rat
2313854Bp343Blood pressure QTL 3433.9life span trait (VT:0005372)age at time of death (CMO:0001193)173199078450909196Rat
1331765Hrtrt15Heart rate QTL 154.094heart pumping trait (VT:2000009)heart rate (CMO:0000002)171533061355836425Rat
1354635Bp245Blood pressure QTL 2456arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)174207316069599340Rat
1354640Scl32Serum cholesterol level QTL 325.4blood HDL cholesterol amount (VT:0000184)blood high density lipoprotein cholesterol level (CMO:0000052)171578159260781592Rat
7488966Bp370Blood pressure QTL 3700.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318457246843Rat
12903980Cm120Cardiac mass QTL 1200.002heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)172365318468653184Rat
12903982Kidm70Kidney mass QTL 700.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)172365318470974005Rat
724549Niddm56Non-insulin dependent diabetes mellitus QTL 560.03blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)173199078476990784Rat
12903981Am17Aortic mass QTL 170.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)172365318468653184Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
2303561Bw91Body weight QTL 912body mass (VT:0001259)body weight (CMO:0000012)17886846253868462Rat
12903979Cm119Cardiac mass QTL 1190.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172365318468653184Rat
4889955Bss93Bone structure and strength QTL 934.4tibia size trait (VT:0100001)tibia cortical bone volume to tibia total bone volume ratio (CMO:0001727)172702794960463643Rat
8552928Pigfal9Plasma insulin-like growth factor 1 level QTL 99blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)172840914773409147Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)173136839173951021Rat
7394837Memor18Memory QTL 18exploratory behavior trait (VT:0010471)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)171864018263640182Rat
1300148Bp192Blood pressure QTL 1923.47arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)173455084373951021Rat
10054088Scort28Serum corticosterone level QTL 282.040.0102blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17452803849528038Rat
1598871Memor5Memory QTL 55.3exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)174054004180387013Rat
1559055Bp278Blood pressure QTL 2780.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318468653184Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)173747984782479847Rat
1354596Bw32Body weight QTL 324.5body mass (VT:0001259)body weight (CMO:0000012)17429913060781592Rat
1354619Bp242Blood pressure QTL 2426.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172459934069599340Rat
61394Bp8Blood pressure QTL 82.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172308056759555013Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)17429913069599340Rat
1581512Cm55Cardiac mass QTL 552.80.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172702794956836890Rat
70157Niddm32Non-insulin dependent diabetes mellitus QTL 324.34blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)172245492450909196Rat
724528Uae4Urinary albumin excretion QTL 44.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)173583708569599340Rat
2302377Scl61Serum cholesterol level QTL 614.36blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)172738994653481766Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17160781592Rat
1354659Scl68Serum cholesterol level QTL 683.9blood VLDL cholesterol amount (VT:0005144)blood very low density lipoprotein cholesterol level (CMO:0000648)171578159260781592Rat
1354628Stl13Serum triglyceride level QTL 133.8blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)172129303960781592Rat
2303627Vencon8Ventilatory control QTL 80.001respiration trait (VT:0001943)tidal volume (CMO:0000222)17452803849528038Rat
2317054Aia12Adjuvant induced arthritis QTL 124.24joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)173828150983281509Rat
2317060Aia26Adjuvant induced arthritis QTL 263.22joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)173828150983281509Rat
10450503Bp386Blood pressure QTL 3860.28arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)173136839162109574Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173199078481292925Rat
1358295Aocep1Aortic cell protein QTL 16.10.00000071thoracic aorta cellular protein amount (VT:0010598)aortic cell percentage174099000585990005Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:228
Count of miRNA genes:156
Interacting mature miRNAs:194
Transcripts:ENSRNOT00000025516, ENSRNOT00000074910
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 1 15 6 19 6 2 2 74 9 18 11 2
Low 42 42 35 35 6 9 26 23 6
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001108415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001395578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006254087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600613 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095892 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095894 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095895 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095897 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ438489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000293 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000077910   ⟹   ENSRNOP00000073656
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1744,549,852 - 44,822,788 (-)Ensembl
Rnor_6.0 Ensembl1746,353,330 - 46,794,845 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000078331   ⟹   ENSRNOP00000073154
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1744,322,014 - 44,822,788 (-)Ensembl
Rnor_6.0 Ensembl1746,387,560 - 46,794,845 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000090663   ⟹   ENSRNOP00000073757
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1744,286,485 - 44,822,788 (-)Ensembl
Rnor_6.0 Ensembl1746,353,330 - 46,794,845 (-)Ensembl
RefSeq Acc Id: NM_001108415   ⟹   NP_001101885
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21744,286,502 - 44,822,788 (-)NCBI
Rnor_6.01746,352,103 - 46,888,788 (-)NCBI
Rnor_5.01756,598,697 - 57,133,816 (+)NCBI
RGSC_v3.41751,989,458 - 52,552,704 (-)RGD
Celera1751,701,962 - 52,225,665 (+)RGD
Sequence:
RefSeq Acc Id: XM_006254087   ⟹   XP_006254149
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21744,286,495 - 44,424,218 (-)NCBI
Rnor_6.01746,352,102 - 46,489,853 (-)NCBI
Rnor_5.01756,598,697 - 57,133,816 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039095892   ⟹   XP_038951820
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21744,286,495 - 44,822,426 (-)NCBI
RefSeq Acc Id: XM_039095893   ⟹   XP_038951821
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21744,286,495 - 44,729,405 (-)NCBI
RefSeq Acc Id: XM_039095894   ⟹   XP_038951822
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21744,286,495 - 44,822,668 (-)NCBI
RefSeq Acc Id: XM_039095895   ⟹   XP_038951823
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21744,286,495 - 44,822,421 (-)NCBI
RefSeq Acc Id: XM_039095896   ⟹   XP_038951824
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21744,286,495 - 44,822,426 (-)NCBI
RefSeq Acc Id: XM_039095897   ⟹   XP_038951825
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21744,286,495 - 44,728,992 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001101885   ⟸   NM_001108415
- Sequence:
RefSeq Acc Id: XP_006254149   ⟸   XM_006254087
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: ENSRNOP00000073757   ⟸   ENSRNOT00000090663
RefSeq Acc Id: ENSRNOP00000073656   ⟸   ENSRNOT00000077910
RefSeq Acc Id: ENSRNOP00000073154   ⟸   ENSRNOT00000078331
RefSeq Acc Id: XP_038951822   ⟸   XM_039095894
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038951824   ⟸   XM_039095896
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038951820   ⟸   XM_039095892
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038951823   ⟸   XM_039095895
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038951821   ⟸   XM_039095893
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038951825   ⟸   XM_039095897
- Peptide Label: isoform X3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G8CYZ7-F1-model_v2 AlphaFold G8CYZ7 1-742 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700506
Promoter ID:EPDNEW_R11022
Type:single initiation site
Name:Elmo1_1
Description:engulfment and cell motility 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01746,794,930 - 46,794,990EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308182 AgrOrtholog
BioCyc Gene G2FUF-9157 BioCyc
Ensembl Genes ENSRNOG00000059705 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000073154.2 UniProtKB/TrEMBL
  ENSRNOP00000073656.2 UniProtKB/TrEMBL
  ENSRNOP00000073757.2 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000077910.2 UniProtKB/TrEMBL
  ENSRNOT00000078331.2 UniProtKB/TrEMBL
  ENSRNOT00000090663.2 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  DUF3361 UniProtKB/TrEMBL
  ELMO1 UniProtKB/TrEMBL
  Engulfment_cell_motility_ELMO UniProtKB/TrEMBL
  PH_type UniProtKB/TrEMBL
  Pleckstrin_homology UniProtKB/TrEMBL
KEGG Report rno:361251 UniProtKB/TrEMBL
NCBI Gene 361251 ENTREZGENE
PANTHER PTHR12771:SF23 UniProtKB/TrEMBL
Pfam DUF3361 UniProtKB/TrEMBL
  ELMO_CED12 UniProtKB/TrEMBL
  PH_12 UniProtKB/TrEMBL
PhenoGen Elmo1 PhenoGen
PROSITE ELMO UniProtKB/TrEMBL
Superfamily-SCOP ARM-type_fold UniProtKB/TrEMBL
UniProt A0A0G2K4S6_RAT UniProtKB/TrEMBL
  A0A0G2K633_RAT UniProtKB/TrEMBL
  D3ZY46_RAT UniProtKB/TrEMBL
  G8CYZ7_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-28 Elmo1  engulfment and cell motility 1  Elmo1  engulfment and cell motility 1, ced-12 homolog (C. elegans)   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Elmo1  engulfment and cell motility 1, ced-12 homolog (C. elegans)   Elmo1_predicted  engulfment and cell motility 1, ced-12 homolog (C. elegans) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Elmo1_predicted  engulfment and cell motility 1, ced-12 homolog (C. elegans) (predicted)      Symbol and Name status set to approved 70820 APPROVED