Mir466b-2 (microRNA mir-466b-2) - Rat Genome Database

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Gene: Mir466b-2 (microRNA mir-466b-2) Rattus norvegicus
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Symbol: Mir466b-2 (Ensembl: Mir466b-4)
Name: microRNA mir-466b-2 (Ensembl:microRNA mir-466b-4)
RGD ID: 14398573
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: rno-mir-466b-2
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81772,942,463 - 72,942,544 (-)NCBIGRCr8
mRatBN7.21768,032,728 - 68,032,809 (-)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx1771,510,953 - 71,511,034 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01775,339,636 - 75,339,717 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01769,382,746 - 69,382,827 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0 Ensembl1772,066,536 - 72,066,617 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1771,809,047 - 71,809,128 (-)EnsemblRnor6.0rn6Rnor6.0
Cytogenetic Map17q12.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


PMID:16381832   PMID:17604727   PMID:20403161  



.

Predicted Targets
Summary Value
Count of predictions:7275
Count of gene targets:4197
Count of transcripts:4553
Interacting mature miRNAs:rno-miR-466b-2-3p, rno-miR-466b-5p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 44 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
1358295Aocep1Aortic cell protein QTL 16.17e-07thoracic aorta cellular protein amount (VT:0010598)aortic cell percentage174099000585990005Rat
70210Cm15Cardiac mass QTL 156.5heart right ventricle mass (VT:0007033)heart right ventricle wet weight (CMO:0000072)175724672370156904Rat
152023626Bp403Blood pressure QTL 4033.86arterial blood pressure trait (VT:2000000)172393042179524188Rat
7411575Bw140Body weight QTL 14030.20.001body mass (VT:0001259)body weight gain (CMO:0000420)174856093586533673Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)173747984782479847Rat
631502Cm26Cardiac mass QTL 263.71heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)176570358081153923Rat
1354588Bvd4Brain ventricular dilatation QTL 45.310.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)175349882882479847Rat
7411577Bw141Body weight QTL 1410.001body mass (VT:0001259)body weight gain (CMO:0000420)176261951686533673Rat
9590107Sffal7Serum free fatty acids level QTL 74.810.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)172840914773409147Rat

1 to 10 of 44 rows



reproductive system
1


RefSeq Transcripts NR_032252 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000071419
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1772,066,536 - 72,066,617 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000072106
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1771,809,047 - 71,809,128 (-)Ensembl
RefSeq Acc Id: NR_032252
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81772,942,463 - 72,942,544 (-)NCBI
mRatBN7.21768,032,728 - 68,032,809 (-)NCBI

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 10 of 10 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSRNOG00000047638 Ensembl
  ENSRNOG00000050541 Ensembl
miRBase MI0006113 ENTREZGENE
NCBI Gene Mir466b-2 ENTREZGENE
PhenoGen Mir466b-2 PhenoGen
RatGTEx ENSRNOG00000047638 RatGTEx
  ENSRNOG00000050541 RatGTEx
RNAcentral URS0000A9B747 RNACentral
  URS0000D50348 RNACentral
  URS0000D54A04 RNACentral
1 to 10 of 10 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-23 Mir466b-2  microRNA mir-466b-2      Symbol and Name status set to provisional 70820 PROVISIONAL