Cm15 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Cm15 (Cardiac mass QTL 15) Rattus norvegicus

Symbol: Cm15
Name: Cardiac mass QTL 15
RGD ID: 70210
Previously known as: Hypoxia-induced right ventricular hypertrophy QTL 1; Hirvh1
Trait: heart right ventricle mass   (VT:0007033)    
Measurement Type: heart right ventricle wet weight   (CMO:0000072)    
LOD Score: 6.5
P Value: Not Available
Variance: 22.0
Inheritance Type: dominant
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21757,246,723 - 70,156,904RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01762,195,703 - 73,981,731RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01763,969,458 - 75,653,670RGDRnor5.0
RGSC_v3.41765,900,398 - 81,612,488RGDRGSC3.4
RGSC_v3.11765,911,232 - 81,623,321RGD
Cross Type: F2
Strains Crossed: WKY/NCruk F344/NHsd WKY.F344-(D17Got91-D17Rat51)/Tja 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Candidate Gene Status
Chrm3 is a candidate Gene for Cm15
Ryr2 is a candidate Gene for Cm15
Slc39a12 is a candidate Gene for Cm15

Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain

References

References - curated
# Reference Title Reference Citation
1. QTL Data Transfer QTL data import from the RatMap database
2. Right ventricular hypertrophy secondary to pulmonary hypertension is linked to rat chromosome 17: evaluation of cardiac ryanodine Ryr2 receptor as a candidate. Zhao L, etal., Circulation 2001 Jan 23;103(3):442-7.
3. The zinc transporter ZIP12 regulates the pulmonary vascular response to chronic hypoxia. Zhao L, etal., Nature. 2015 Aug 20;524(7565):356-60. doi: 10.1038/nature14620. Epub 2015 Aug 10.

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1560525Fzd8frizzled class receptor 8175731292457320551Rat
628621Gjd4gap junction protein, delta 4175734884457352601Rat
1565969Ccnycyclin Y175738500257512860Rat
6501948LOC100909729uncharacterized LOC100909729175751315957514759Rat
9152346LOC103690071interaptin-like175762154257900975Rat
9472036PotedPOTE ankyrin domain family member D175794212457975149Rat
1566097Anlnl1anillin, actin binding protein-like 1175798534057995824Rat
621272Lgals8galectin 8175802465258052764Rat
1564769Heatr1HEAT repeat containing 1175805328858093895Rat
1308097Actn2actinin alpha 2175814333458210622Rat
41054517Trnas-aga47transfer RNA serine (anticodon AGA) 47175819156958191644Rat
621283Mtr5-methyltetrahydrofolate-homocysteine methyltransferase175821999858308560Rat
41377181LOC120097915uncharacterized LOC120097915175824370458247835Rat
41125104LOC120097928SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5-like175827429558278695Rat
41267736Rps7-ps15ribosomal protein S7, pseudogene 15175832060758324029Rat
620314Ryr2ryanodine receptor 2175838992558975641Rat
41332867LOC120098026small nucleolar RNA U3175842230958422433Rat
628708Zp4zona pellucida glycoprotein 4175900564959012202Rat
41156892LOC120097906uncharacterized LOC120097906175913071959138035Rat
41243501LOC120097813uncharacterized LOC120097813175933758259355633Rat
1589973Nsa2-ps11NSA2 ribosome biogenesis factor, pseudogene 11175962502059625946Rat
2343Chrm3cholinergic receptor, muscarinic 3176000513760467250Rat
1303252Zmynd11zinc finger, MYND-type containing 11176054266960631913Rat
1560155Dip2cdisco-interacting protein 2 homolog C176064734661032467Rat
11470481LOC108348621uncharacterized LOC108348621176070470960733102Rat
41219403Adi1-ps1acireductone dioxygenase 1, pseudogene 1176098927360989828Rat
9362362LOC10369411660S ribosomal protein L22 pseudogene176108489261085261Rat
1310713Larp4bLa ribonucleoprotein 4B176113866361217423Rat
41242720LOC120097870uncharacterized LOC120097870176124753661263382Rat
620783Gtpbp4GTP binding protein 4176130803361328184Rat
1559783Idi2isopentenyl-diphosphate delta isomerase 2176133138561334987Rat
41339945LOC120097764isopentenyl-diphosphate delta-isomerase 2-like176133862261349795Rat
1564347Idi2l2isopentenyl-diphosphate delta isomerase 2 like 2176137285361386459Rat
7617990LOC102552003uncharacterized LOC102552003176138493861387088Rat
9378476LOC103690178nucleolar GTP-binding protein 1-like176140456161417990Rat
9352023Idi2-ps1isopentenyl-diphosphate delta isomerase 2, pseudogene 1176142035761423924Rat
7740538LOC102550988isopentenyl-diphosphate delta-isomerase 2-like176145192061457799Rat
2322079LOC100360477hypothetical protein LOC100360477176147703761483516Rat
1589708Eef1g-ps11eukaryotic translation elongation factor 1 gamma, pseudogene 11176149758161498918Rat
7541008LOC102551575isopentenyl-diphosphate delta-isomerase 2-like176150429461507015Rat
1564999Idi2l3isopentenyl-diphosphate delta isomerase 2 like 3176151813861535484Rat
40959177Eef1g-ps8eukaryotic translation elongation factor 1 gamma, pseudogene 8176155698761562152Rat
6489760LOC100911936uncharacterized LOC100911936176156873761578142Rat
621835Idi1isopentenyl-diphosphate delta isomerase 1176162959261637357Rat
1306189Wdr37WD repeat domain 37176163725861703677Rat
621519Adarb2adenosine deaminase RNA specific B2176175043762300984Rat
7646455LOC102552293uncharacterized LOC102552293176194057461982314Rat
2325073Elobl1elongin B like 1176220896662209274Rat
11485055LOC108348614uncharacterized LOC108348614176329355663296453Rat
1585155Moap1-ps1modulator of apoptosis 1, pseudogene 1176338020763381740Rat
6497110Atp5mg-ps7ATP synthase membrane subunit g, pseudogene 7176363638763636687Rat
1589707Mcm7-ps1minichromosome maintenance complex component 7, pseudogene 1176366263563666781Rat
61893Pfkpphosphofructokinase, platelet176372974363794026Rat
1310998Pitrm1pitrilysin metallopeptidase 1176379567063827317Rat
1589706Zzz3-ps1zinc finger, ZZ-type containing 3, pseudogene 1176387960163881399Rat
11406958LOC108348582uncharacterized LOC108348582176401660964037489Rat
1589705Smarce1-ps3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1, pseudogene 3176408583764087092Rat
1595871Hspa8-ps5heat shock protein family A (Hsp70) member 8, pseudogene 5176409395964095858Rat
62389Klf6KLF transcription factor 6176453945664548451Rat
41363710LOC120098005small nucleolar RNA SNORA17176467024664670368Rat
41220445LOC120097984small nucleolar RNA SNORA48176469517764695319Rat
7686967LOC102554523uncharacterized LOC102554523176483146264865907Rat
41200047LOC120097925uncharacterized LOC120097925176494795064970825Rat
41048340LOC120097919uncharacterized LOC120097919176555315765559311Rat
41044963LOC120098044U6 spliceosomal RNA176557634565576451Rat
11401537LOC108348616uncharacterized LOC108348616176571556665723420Rat
1309599Akr1e2aldo-keto reductase family 1, member E2176573590965750441Rat
41341161Srsf3-ps9serine and arginine rich splicing factor 3, pseudogene 9176575656765759644Rat
1311841Akr1c2aldo-keto reductase family 1, member C2176575977865808013Rat
1306847Akr1c1aldo-keto reductase family 1, member C1176581047465837385Rat
1564865AKR1C3l1aldo-keto reductase family 1 member C3-like 1176584758065881488Rat
1559604Akr1c12l1aldo-keto reductase family 1, member C12-like 1176593783465948344Rat
1589704Vdac1-ps6voltage-dependent anion channel 1, pseudogene 6176595464865959462Rat
1308232Akr1c13aldo-keto reductase family 1, member C13176596418665997598Rat
1562954Akr1c19aldo-keto reductase family 1, member C19176600135866027226Rat
1359406Akr1c12aldo-keto reductase family 1, member C12176604537666061496Rat
41218517Slc23a2-ps1solute carrier family 23 member 2, pseudogene 1176607559066082748Rat
708428Akr1c3aldo-keto reductase family 1, member C3176611097066127867Rat
708361Akr1c14aldo-keto reductase family 1, member C14176615628666173277Rat
1307514Akr1c15aldo-keto reductase family 1, member C15176618149366208090Rat
41155374LOC120097737uncharacterized LOC120097737176620708866215750Rat
1562213Ucn3urocortin 3176630974866315996Rat
1305289Tubal3tubulin, alpha-like 3176632373366332423Rat
1305034Net1neuroepithelial cell transforming 1176634125166370445Rat
9474191LOC103694125uncharacterized LOC103694125176639104866393245Rat
1310047Calml5calmodulin-like 5176639443366395352Rat
1305499Calml3calmodulin-like 3176641984466423083Rat
41186790LOC120097832uncharacterized LOC120097832176650409166507987Rat
1582824Nip7-ps15nucleolar pre-rRNA processing protein NIP7, pseudogene 15176652539566526387Rat
1564088Rpl29-ps3ribosomal protein L29, pseudogene 3176655246866553027Rat
1310387Asb13ankyrin repeat and SOCS box-containing 13176656465366583365Rat
1564456Tasor2transcription activation suppressor family member 2176658355466650127Rat
61802Gdi2GDP dissociation inhibitor 2176664961666676299Rat
41312831LOC120097798uncharacterized LOC120097798176668645566688084Rat
41298822LOC120097902uncharacterized LOC120097902176671331566716474Rat
41193472LOC120097862uncharacterized LOC120097862176672547766727913Rat
1311405Ankrd16ankyrin repeat domain 16176673532566748533Rat
1306298Fbh1F-box DNA helicase 1176674950666787590Rat
1305149Il15rainterleukin 15 receptor subunit alpha176680230066831973Rat
41401159Arpc5l-ps2actin related protein 2/3 complex, subunit 5-like, pseudogene 2176683672066837695Rat
2895Il2rainterleukin 2 receptor subunit alpha176684997466898665Rat
7519062Psmc6-ps1proteasome 26S subunit, ATPase 6, pseudogene 1176693180566937314Rat
1311208Rbm17RNA binding motif protein 17176693714066954034Rat
619776Pfkfb36-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3176698362967064702Rat
41387287LOC120098047U6 spliceosomal RNA176700865167008754Rat
41105207LOC120097756uncharacterized LOC120097756176714395667148274Rat
620968Prkcqprotein kinase C, theta176724639467379049Rat
7532113LOC102552793uncharacterized LOC102552793176742484467433157Rat
1564416Hnrnpa1-ps26heterogeneous nuclear ribonucleoprotein A1, pseudogene 26176744541467446386Rat
41134540LOC120097974small nucleolar RNA SNORA68176753442767534557Rat
6486636Atp5f1c-ps4ATP synthase F1 subunit gamma, pseudogene 4176758833167588976Rat
11517690LOC108348487nuclear cap-binding protein subunit 2 pseudogene176761583867621169Rat
2321948Prmt1-ps1protein arginine methyltransferase 1, pseudogene 1176762545467626376Rat
41360715LOC120097741uncharacterized LOC120097741176768061267766669Rat
7578249LOC102552867uncharacterized LOC102552867176768083067715001Rat
2321902Fth1-ps3ferritin heavy chain 1, pseudogene 3176785430467855385Rat
1305027Sfmbt2Scm-like with four mbt domains 2176793429668128905Rat
4888560Mir466dmicroRNA 466d176800326768003359Rat
9685628Mir466cmicroRNA 466c176801786468017942Rat
14398573Mir466b-2microRNA mir-466b-2176803272868032809Rat
14398587Mir466b-1microRNA mir-466b-1176803575868035843Rat
41260975LOC120097910uncharacterized LOC120097910176815475868158084Rat
40950915LOC120097951uncharacterized LOC120097951176823747168242527Rat
1591485Itih5inter-alpha-trypsin inhibitor heavy chain 5176824811568352216Rat
41060414LOC120097950uncharacterized LOC120097950176826388568273069Rat
41184525LOC120097849uncharacterized LOC120097849176835628368360010Rat
1565426Itih2inter-alpha-trypsin inhibitor heavy chain 2176837557468411849Rat
1596107KinKin17 DNA and RNA binding protein176841348368431392Rat
620011Atp5f1cATP synthase F1 subunit gamma176842392768446169Rat
41303092LOC120097988small nucleolar RNA SNORA17176842872368428851Rat
7541609LOC102546431uncharacterized LOC102546431176844292268457029Rat
2324594Taf3TATA-box binding protein associated factor 3176845538968608367Rat
41224909LOC120097843uncharacterized LOC120097843176863732268641249Rat
621250Gata3GATA binding protein 3176864376068666000Rat
7745365LOC102546657uncharacterized LOC102546657176895481068996252Rat
41264459LOC120097778uncharacterized LOC120097778176897314669007426Rat
7751577LOC102546763uncharacterized LOC102546763176926251069321716Rat
40997098LOC120097918uncharacterized LOC120097918176941217069418345Rat
41049176LOC120097994small nucleolar RNA SNORA17176968051769680648Rat
41205386LOC120098030U4 spliceosomal RNA176990167369901783Rat
41096094LOC120097900uncharacterized LOC120097900176996062769985753Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
10348D17Mit4215176046341260463643Ratregion
10349D17Arb7221176046340560463642Ratregion
10350D17Wox12121176046350060463637Ratregion
10351D17Wox13134176046348360463633Ratregion
34391D17Mgh9148176811706768117215Ratregion
36211D17Rat34172176227078862270949Ratregion
36315D17Rat41175176883571268835887Ratregion
37234D17Rat97234176210933362109574Ratregion
37404D17Rat82199176877890768779104Ratregion
35258D17Rat36188176364000963640182Ratregion
35473D17Rat58143176959919769599340Ratregion
37762D17Rat170170175949767959497857Ratregion
36783D17Rat172126176759541267595534Ratregion
34989D17Rat39154176570358065703715Ratregion
35052D17Rat33126176011018860110323Ratregion
35062D17Rat30170175812456458124741Ratregion
35136D17Rat37164176475909664759263Ratregion
35585D17Rat151166176078142660781592Ratregion
35883D17Rat44141177015677770156904Ratregion
35893D17Rat38158176355506163555219Ratregion
39692D17Rat139133176880741568807548Ratregion
39786D17Rat129165176869929768699464Ratregion
37998D17Rat96205176704777767047980Ratregion
40400D17Rat148143175803800658038147Ratregion
40114D17Rat122125176000088060000997Ratregion
40198D17Rat123168175876879458768965Ratregion
40316D17Rat124128176117751661177650Ratregion
38798D17Rat150220175801245258012678Ratregion
39488D17Rat127244176455464964554895Ratregion
39566D17Rat126246176419468864194936Ratregion
42045D17Arb5127175869183558691962Ratregion
41510D17Rat128146176405521464055360Ratregion
42418D17Rat68171175863292958633100Ratregion
43098D17Rat149133175816531158165446Ratregion
43101D17Rat152229176855090968551143Ratregion
43102D17Rat153228176961631469616542Ratregion
45480D17Got79108175881625858816366Ratregion
45481D17Got77108175854148258541590Ratregion
45482D17Got75218175996373459963952Ratregion
45484D17Got74195176001893760019130Ratregion
45485D17Wox9108175724672357246843Ratregion
45487D17Hmgc2202176108840561088605Ratregion
45488D17Got80171176348992063490091Ratregion
45489D17Got124153176437868564378838Ratregion
45491D17Got87124176691767666917800Ratregion
45494D17Got82292176794876467949054Ratregion
45495D17Got88150176761546867615619Ratregion
45496D17Wox6152176881769968817853Ratregion
45497D17Got84218176769069667690914Ratregion
45498D17Got89221176838026868380486Ratregion
45499D17Wox21153176881769168817870Ratregion
60772D17Wox4162175813056958130741Ratregion
60156D17Got71144175793532457935468Ratregion
60156D17Got71144175793532457935468Ratregion
625788D17Got85145176748978267489927Ratregion
629582D17Got83209176683600366836209Ratregion
61300D17Mco3259175955501359555289Ratregion
1556754D17Chm14199176878393768784138Ratregion
1631795D17Got216106176103579161035895Ratregion
1635873D17Wox31196176617551566175711Ratregion
1637583D17Got22688176836697968367067Ratregion
7394844rs106534785176114994661149946Ratregion
7206732MARC_4455-4456:966894277:1115176370976963709885Ratregion
5038726AW04837697175738158457381681Ratregion
5038868RH127379220176667669266676912Ratregion
5039274RH127612211176379369263793903Ratregion
5028629RH124435278175805806058058338Ratregion
7206236Fzd882175731770057317782Ratregion
5031508AU048093284176215714862157432Ratregion
5028769RH142262199176453980364540002Ratregion
5031690AU047474241175760185857602099Ratregion
5034482BF41563097176054527560545372Ratregion
5031906AU046752267176827789368278160Ratregion
5034754AI009647198176664861366648811Ratregion
5027119RH70526130175944187759442007Ratregion
5029791BE102654176176680861266808788Ratregion
5025108C86813234176453956564539798Ratregion
5030617BE113707158176656501366565171Ratregion
5033507RH139079145176837557368375718Ratregion
5028567C76891232175789663457896866Ratregion
5028567C76891232175789663457896866Ratregion
5055083RH143596165175834096158341126Ratregion
5053671RH142783108176064869960648807Ratregion
5055361RH143757157176615702466157181Ratregion
5054587RH143310236176163101761631258Ratregion
5056465RH144394240175751447757514718Ratregion
5050586RH134141164175821329858213462Ratregion
5049820RH133700185176667549866675683Ratregion
5051052RH134411220176724657967246799Ratregion
5054061RH143008120176685005766850177Ratregion
5050252RH133949206176898922568989431Ratregion
5051423AW214366123176762553267625655Ratregion
5053361RH142604161176133161861331779Ratregion
5053361RH142604161176133161861331779Ratregion
5040790RH128485184176454238964542573Ratregion
5044366RH130561208176162966161629869Ratregion
5041356RH128810194176637012266370316Ratregion
5045974RH131486217175897533058975547Ratregion
5044462RH130616214176642277466422988Ratregion
5044942RH130892198176881994968820147Ratregion
5047888RH132586192176866504468665236Ratregion
5049240RH133366183176678731066787493Ratregion
5042152RH129270203176113881661139019Ratregion
5048538RH132961187176170344061703620Ratregion
5048610RH133003209176788537467885713Ratregion
5049640RH133597189176379581663796005Ratregion
5039398RH127683215176063156860631783Ratregion
5040538RH128341206175738139057381596Ratregion
5043004RH129774213176714642867146641Ratregion
5039842RH127938189176575009965750288Ratregion
5042898RH129710218176860699968607217Ratregion
5072340RH136792228176860810368608331Ratregion
5076346RH139122143176873649568736638Ratregion
5072750RH137031213176132859461328807Ratregion
5072750RH137031213176132859461328807Ratregion
5072750RH137031213176141788961418102Ratregion
5072750RH137031213176141788961418102Ratregion
5076080RH138967152176064864860648800Ratregion
5077668RH139889198176163748061637678Ratregion
5075740RH138769212176695436666954578Ratregion
5077842RH139991196176860810368608299Ratregion
5077952RH140056192176103023461030426Ratregion
5079136RH140756175176594808965948264Ratregion
5079136RH140756175176599734465997519Ratregion
5070886RH134762188176639463566394823Ratregion
5073222RH137311180175738484357385023Ratregion
5073710RH137593155176175060561750759Ratregion
5072448RH136855214176825227968252493Ratregion
5064966BE108794160176656245166562611Ratregion
5067892AU047473258176894229368942771Ratregion
5067892AU047473258176894251768942771Ratregion
5068832AU046899269176157905261579322Ratregion
5068832AU046899269176157905261579322Ratregion
5069730AU046308122176272080462720926Ratregion
5061874AW533955177176598174665981926Ratregion
5062656BF403708220176210119262101412Ratregion
5065284BE121379151176573632165736472Ratregion
5060586BE098513150176165221361652363Ratregion
5064330BE114414191176841351868413709Ratregion
5064402BI302100160176619636666196526Ratregion
5061476BE111848159175731299857313157Ratregion
5086995BE106817172176658207166582243Ratregion
5086555BE114437173176908521669085389Ratregion
5087283AW531528186175817987458180060Ratregion
5082683BF416571213176182705361827266Ratregion
5089939AU049454268176099615560996421Ratregion
5089281AU049062188175979416959794357Ratregion
5090669AU049890293176437563064375921Ratregion
5088605AU048669185176743504567435230Ratregion
5089685AU049302280176140062661400896Ratregion
5084406AI40898296176167090961671005Ratregion
5080998RH141904210176639017766390387Ratregion
5085671AW535579181176863918268639363Ratregion
5090103AU049552248175876877858769026Ratregion
5081382AI385205182176695243966953772Ratregion
5084484AI013758154176793430967934463Ratregion
5086106AI233437160176822796468228124Ratregion
5081230RH142039166175731804557318211Ratregion
5086634BQ205792172176455217764552349Ratregion
5085713AA849380155176118296261183117Ratregion
5503076Actn2121175817097158172160Ratregion
5507549G06312246176063161260631858Ratregion
5507709UniSTS:25682101176063174660631847Ratregion
5504308D10S1340E111176063174660631857Ratregion
5504887ha30461560175742191857423478Ratregion
5504999Fzd8155175731681457316969Ratregion
5504472PMC21940P1246175897512058975366Ratregion
5504805Hrmt1l2212176762614767626358Ratregion
5505774UniSTS:4930721679176674681366748492Ratregion
5506833G46301184176368764763687831Ratregion
5507041fb22g09.x1919176685866666859585Ratregion
5507271fc41h02.x1817175992373059924675Ratregion
5507287fb54b04.x10176000564260006974Ratregion
5507287fb54b04.x10176000564260006996Ratregion
5500741G26357217176062989760630114Ratregion
5500793stSG625620867175930361859304485Ratregion
5505530A005N471694175787883057880524Ratregion
5502120MARC_5003-5004:996690032:1176176844133968442557Ratregion
5506907G47699239176249047262490711Ratregion
5502529RH125200126176454212064542245Ratregion
152025237rs1057390160175992909559929095Ratregion
Position Markers

Flank 1: (D17Wox9)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21757,246,723 - 57,246,843 (+)MAPPER
Rnor_6.01762,195,703 - 62,195,822NCBI
Rnor_5.01763,969,458 - 63,969,577UniSTS
RGSC_v3.41765,900,398 - 65,900,518RGD
RGSC_v3.41765,900,399 - 65,900,518UniSTS
RGSC_v3.11765,911,232 - 65,911,351RGD
Celera1758,532,268 - 58,532,375UniSTS
RH 3.4 Map17588.6UniSTS
RH 3.4 Map17588.6RGD
RH 2.0 Map17510.6RGD
Cytogenetic Map17 RGD
Peak: (D17Rat41)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21768,835,712 - 68,835,887 (+)MAPPER
Rnor_6.01772,632,375 - 72,632,549NCBI
Rnor_5.01774,317,162 - 74,317,336UniSTS
RGSC_v3.41780,234,241 - 80,234,510RGD
RGSC_v3.41780,234,337 - 80,234,511UniSTS
RGSC_v3.11780,245,074 - 80,245,343RGD
Celera1768,323,986 - 68,324,160UniSTS
RH 3.4 Map17683.4UniSTS
RH 3.4 Map17683.4RGD
RH 2.0 Map17588.5RGD
SHRSP x BN Map1738.2699RGD
FHH x ACI Map1750.4999RGD
Flank 2: (D17Rat44)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21770,156,777 - 70,156,904 (+)MAPPER
Rnor_6.01773,981,605 - 73,981,731NCBI
Rnor_5.01775,653,544 - 75,653,670UniSTS
RGSC_v3.41781,612,361 - 81,612,488RGD
RGSC_v3.41781,612,362 - 81,612,488UniSTS
RGSC_v3.11781,623,195 - 81,623,321RGD
RH 3.4 Map17689.4UniSTS
RH 3.4 Map17689.4RGD
RH 2.0 Map17603.1RGD
SHRSP x BN Map1740.8899RGD


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354640Scl32Serum cholesterol level QTL 325.4blood HDL cholesterol amount (VT:0000184)blood high density lipoprotein cholesterol level (CMO:0000052)171578159260781592Rat
7411575Bw140Body weight QTL 14030.20.001body mass (VT:0001259)body weight gain (CMO:0000420)174856093586533673Rat
7411577Bw141Body weight QTL 1410.001body mass (VT:0001259)body weight gain (CMO:0000420)176261951686533673Rat
1354654Spl7Serum phospholipid level QTL 75.5blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)175089090860781592Rat
1598871Memor5Memory QTL 55.3exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)174054004180387013Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
1354628Stl13Serum triglyceride level QTL 133.8blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)172129303960781592Rat
1354629Scl31Serum cholesterol level QTL 314.1blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)175089090860781592Rat
1354630Cm34Cardiac mass QTL 348.7heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)17429913069599340Rat
1600398Edcs5Endometrial carcinoma susceptibility QTL 52.2uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)175724672370852846Rat
1559055Bp278Blood pressure QTL 2780.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318468653184Rat
152025238Slep14Serum leptin concentration QTL 144.62blood leptin amount (VT:0005667)172418489079524188Rat
61466Niddm12Non-insulin dependent diabetes mellitus QTL 123.20.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)175402992960463637Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)17429913069599340Rat
1354635Bp245Blood pressure QTL 2456arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)174207316069599340Rat
8694181Bw151Body weight QTL 1514.360.001body mass (VT:0001259)body weight gain (CMO:0000420)174856093586533673Rat
1300148Bp192Blood pressure QTL 1923.47arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)173455084373951021Rat
2317060Aia26Adjuvant induced arthritis QTL 263.22joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)173828150983281509Rat
4889955Bss93Bone structure and strength QTL 934.4tibia size trait (VT:0100001)tibia cortical bone volume to tibia total bone volume ratio (CMO:0001727)172702794960463643Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)173136839173951021Rat
1300131Bp193Blood pressure QTL 1933.3arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)176364000973951021Rat
7488963Bp369Blood pressure QTL 3690.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)175900564977910000Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173199078481292925Rat
152023740Bp406Blood pressure QTL 4066.06arterial blood pressure trait (VT:2000000)172393042179524188Rat
7488966Bp370Blood pressure QTL 3700.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318457246843Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17160781592Rat
152023737Bp405Blood pressure QTL 4055.06arterial blood pressure trait (VT:2000000)2393042179524188Rat
1354659Scl68Serum cholesterol level QTL 683.9blood VLDL cholesterol amount (VT:0005144)blood very low density lipoprotein cholesterol level (CMO:0000648)171578159260781592Rat
152023736Bp404Blood pressure QTL 4043.78arterial blood pressure trait (VT:2000000)172393042179524188Rat
724528Uae4Urinary albumin excretion QTL 44.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)173583708569599340Rat
2302365Gluco40Glucose level QTL 404.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)175724684382046127Rat
631497Bp98Blood pressure QTL 983.66arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)174135465160463643Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
70210Cm15Cardiac mass QTL 156.5heart right ventricle mass (VT:0007033)heart right ventricle wet weight (CMO:0000072)175724672370156904Rat
1358295Aocep1Aortic cell protein QTL 16.17e-07thoracic aorta cellular protein amount (VT:0010598)aortic cell percentage174099000585990005Rat
152023626Bp403Blood pressure QTL 4033.86arterial blood pressure trait (VT:2000000)172393042179524188Rat
631502Cm26Cardiac mass QTL 263.71heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)176570358081153923Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)173747984782479847Rat
1354588Bvd4Brain ventricular dilatation QTL 45.310.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)175349882882479847Rat
9590107Sffal7Serum free fatty acids level QTL 74.810.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)172840914773409147Rat
2317038Ginf3Gastrointestinal inflammation QTL 32.890.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)174992015486533673Rat
724549Niddm56Non-insulin dependent diabetes mellitus QTL 560.03blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)173199078476990784Rat
61394Bp8Blood pressure QTL 82.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172308056759555013Rat
2317045Aia11Adjuvant induced arthritis QTL 114.06joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)176078142686533673Rat
10450503Bp386Blood pressure QTL 3860.28arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)173136839162109574Rat
2317054Aia12Adjuvant induced arthritis QTL 124.24joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)173828150983281509Rat
2317053Aia25Adjuvant induced arthritis QTL 252.69joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)175090919660781426Rat
8552928Pigfal9Plasma insulin-like growth factor 1 level QTL 99blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)172840914773409147Rat
7394837Memor18Memory QTL 18exploratory behavior trait (VT:0010471)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)175639647763640182Rat
12903980Cm120Cardiac mass QTL 1200.002heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)172365318468653184Rat
12903981Am17Aortic mass QTL 170.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)172365318468653184Rat
12903982Kidm70Kidney mass QTL 700.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)172365318470974005Rat
4889894Eae33Experimental allergic encephalomyelitis QTL 335.20.0001nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)175090909986022412Rat
12903978Cm118Cardiac mass QTL 1180.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)172365318468653184Rat
1354619Bp242Blood pressure QTL 2426.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172459934069599340Rat
12903979Cm119Cardiac mass QTL 1190.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172365318468653184Rat
1354596Bw32Body weight QTL 324.5body mass (VT:0001259)body weight (CMO:0000012)17429913060781592Rat
2303580Gluco49Glucose level QTL 492blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)175004027186533673Rat


Additional Information

Database Acc Id Source(s)
NCBI Gene Cm15


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-08 Cm15  Cardiac mass QTL 15  Hirvh1  Hypoxia-induced right ventricular hypertrophy QTL 1  Symbol and Name updated 1299863 APPROVED

RGD Curation Notes
Note Type Note Reference
qtl_gene QTL contains Chrm3 and Ryr2; genetic study implicates Ryr2 as candidate gene 69699
qtl_gene Ryr2 was localized within this QTL by flourescence in situ hybridization (FISH position 17q12.2-q12.3) 69699
qtl_general LOD = 6.5 when analyzed assuming dominant or free genetic model, LOD = 4.8 for additive model, and LOD = 0.9 for recessive model 69699
qtl_map 1-LOD support interval is 5 cM 69699