Tbce (tubulin folding cofactor E) - Rat Genome Database

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Gene: Tbce (tubulin folding cofactor E) Rattus norvegicus
Analyze
Symbol: Tbce
Name: tubulin folding cofactor E
RGD ID: 1305533
Description: Predicted to enable alpha-tubulin binding activity. Predicted to be involved in mitotic spindle organization; post-chaperonin tubulin folding pathway; and tubulin complex assembly. Predicted to act upstream of or within several processes, including adult locomotory behavior; muscle atrophy; and peripheral nervous system neuron axonogenesis. Predicted to be located in cytoskeleton. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in Kenny-Caffey syndrome type 1; hypoparathyroidism; and hypoparathyroidism-retardation-dysmorphism syndrome. Orthologous to human TBCE (tubulin folding cofactor E); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC361255; MGC108815; tubulin-folding cofactor E; tubulin-specific chaperone E
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21751,290,143 - 51,336,090 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1751,290,202 - 51,336,089 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1754,459,035 - 54,504,526 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01758,461,975 - 58,507,461 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01752,593,177 - 52,638,508 (+)NCBIRnor_WKY
Rnor_6.01753,983,126 - 54,029,028 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1753,983,182 - 54,029,027 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01751,676,746 - 51,723,130 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41759,485,451 - 59,533,041 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11759,496,283 - 59,543,873 (+)NCBI
Celera1747,297,977 - 47,343,424 (+)NCBICelera
Cytogenetic Map17q12.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. Mutation of TBCE causes hypoparathyroidism-retardation-dysmorphism and autosomal recessive Kenny-Caffey syndrome. Parvari R, etal., Nat Genet. 2002 Nov;32(3):448-52. Epub 2002 Oct 21.
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:7472523   PMID:11847227   PMID:12389029   PMID:12446740   PMID:12477932   PMID:15489334   PMID:27666369  


Genomics

Comparative Map Data
Tbce
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21751,290,143 - 51,336,090 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1751,290,202 - 51,336,089 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1754,459,035 - 54,504,526 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01758,461,975 - 58,507,461 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01752,593,177 - 52,638,508 (+)NCBIRnor_WKY
Rnor_6.01753,983,126 - 54,029,028 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1753,983,182 - 54,029,027 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01751,676,746 - 51,723,130 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41759,485,451 - 59,533,041 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11759,496,283 - 59,543,873 (+)NCBI
Celera1747,297,977 - 47,343,424 (+)NCBICelera
Cytogenetic Map17q12.1NCBI
TBCE
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381235,367,427 - 235,452,443 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1235,367,360 - 235,452,443 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl1235,328,570 - 235,448,952 (+)EnsemblGRCh38hg38GRCh38
GRCh371235,530,742 - 235,615,756 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361233,597,351 - 233,678,903 (+)NCBINCBI36Build 36hg18NCBI36
Build 341231,856,811 - 231,938,321NCBI
Celera1208,773,486 - 208,855,524 (+)NCBICelera
Cytogenetic Map1q42.3NCBI
HuRef1205,979,723 - 206,063,927 (+)NCBIHuRef
CHM1_11236,803,044 - 236,884,877 (+)NCBICHM1_1
T2T-CHM13v2.01234,759,155 - 234,848,336 (+)NCBIT2T-CHM13v2.0
Tbce
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391314,172,532 - 14,214,235 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1314,172,534 - 14,214,223 (-)EnsemblGRCm39 Ensembl
GRCm381313,997,947 - 14,039,650 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1313,997,949 - 14,039,638 (-)EnsemblGRCm38mm10GRCm38
MGSCv371314,090,218 - 14,131,867 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361313,790,077 - 13,831,726 (-)NCBIMGSCv36mm8
Celera1314,305,650 - 14,346,667 (-)NCBICelera
Cytogenetic Map13A1NCBI
cM Map135.29NCBI
Tbce
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554924,502,897 - 4,558,697 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554924,502,705 - 4,573,126 (-)NCBIChiLan1.0ChiLan1.0
TBCE
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11215,929,658 - 216,020,613 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1215,929,658 - 216,020,613 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01210,881,078 - 211,008,686 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
TBCE
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.144,490,892 - 4,569,401 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl44,490,994 - 4,569,357 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha44,473,098 - 4,551,614 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.044,512,625 - 4,591,187 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl44,512,629 - 4,591,155 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.144,523,866 - 4,602,326 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.044,641,317 - 4,719,844 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.044,862,950 - 4,941,668 (-)NCBIUU_Cfam_GSD_1.0
Tbce
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934440,882,963 - 40,931,750 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648417,046,284 - 17,095,744 (-)EnsemblSpeTri2.0
SpeTri2.0NW_00493648417,048,187 - 17,097,414 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TBCE
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1455,816,668 - 55,901,171 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11455,816,663 - 55,901,215 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21459,954,790 - 59,986,383 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TBCE
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12572,544,942 - 72,616,716 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2572,545,012 - 72,612,622 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605574,568,863 - 74,652,576 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tbce
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477515,067,044 - 15,133,008 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477515,067,044 - 15,132,690 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tbce
250 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:48
Count of miRNA genes:45
Interacting mature miRNAs:46
Transcripts:ENSRNOT00000040743
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17160781592Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat
1354596Bw32Body weight QTL 324.5body mass (VT:0001259)body weight (CMO:0000012)17429913060781592Rat
1354630Cm34Cardiac mass QTL 348.7heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)17429913069599340Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)17429913069599340Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
2303561Bw91Body weight QTL 912body mass (VT:0001259)body weight (CMO:0000012)17886846253868462Rat
1331765Hrtrt15Heart rate QTL 154.094heart pumping trait (VT:2000009)heart rate (CMO:0000002)171533061355836425Rat
1354640Scl32Serum cholesterol level QTL 325.4blood HDL cholesterol amount (VT:0000184)blood high density lipoprotein cholesterol level (CMO:0000052)171578159260781592Rat
1354659Scl68Serum cholesterol level QTL 683.9blood VLDL cholesterol amount (VT:0005144)blood very low density lipoprotein cholesterol level (CMO:0000648)171578159260781592Rat
7394837Memor18Memory QTL 18exploratory behavior trait (VT:0010471)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)171864018263640182Rat
1354628Stl13Serum triglyceride level QTL 133.8blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)172129303960781592Rat
61394Bp8Blood pressure QTL 82.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172308056759555013Rat
7488966Bp370Blood pressure QTL 3700.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318457246843Rat
12903978Cm118Cardiac mass QTL 1180.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)172365318468653184Rat
12903979Cm119Cardiac mass QTL 1190.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172365318468653184Rat
12903980Cm120Cardiac mass QTL 1200.002heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)172365318468653184Rat
12903981Am17Aortic mass QTL 170.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)172365318468653184Rat
1559055Bp278Blood pressure QTL 2780.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318468653184Rat
12903982Kidm70Kidney mass QTL 700.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)172365318470974005Rat
1354619Bp242Blood pressure QTL 2426.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172459934069599340Rat
1581512Cm55Cardiac mass QTL 552.80.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172702794956836890Rat
4889955Bss93Bone structure and strength QTL 934.4tibia size trait (VT:0100001)tibia cortical bone volume to tibia total bone volume ratio (CMO:0001727)172702794960463643Rat
2302377Scl61Serum cholesterol level QTL 614.36blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)172738994653481766Rat
8552928Pigfal9Plasma insulin-like growth factor 1 level QTL 99blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)172840914773409147Rat
9590107Sffal7Serum free fatty acids level QTL 74.810.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)172840914773409147Rat
10450503Bp386Blood pressure QTL 3860.28arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)173136839162109574Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)173136839173951021Rat
724549Niddm56Non-insulin dependent diabetes mellitus QTL 560.03blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)173199078476990784Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173199078481292925Rat
1300148Bp192Blood pressure QTL 1923.47arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)173455084373951021Rat
724528Uae4Urinary albumin excretion QTL 44.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)173583708569599340Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)173747984782479847Rat
2317054Aia12Adjuvant induced arthritis QTL 124.24joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)173828150983281509Rat
2317060Aia26Adjuvant induced arthritis QTL 263.22joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)173828150983281509Rat
1598871Memor5Memory QTL 55.3exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)174054004180387013Rat
1358295Aocep1Aortic cell protein QTL 16.10.00000071thoracic aorta cellular protein amount (VT:0010598)aortic cell percentage174099000585990005Rat
631497Bp98Blood pressure QTL 983.66arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)174135465160463643Rat
1354635Bp245Blood pressure QTL 2456arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)174207316069599340Rat
1354635Bp245Blood pressure QTL 2456arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)174207316069599340Rat
7411575Bw140Body weight QTL 14030.20.001body mass (VT:0001259)body weight gain (CMO:0000420)174856093586533673Rat
8694181Bw151Body weight QTL 1514.360.001body mass (VT:0001259)body weight gain (CMO:0000420)174856093586533673Rat
2317038Ginf3Gastrointestinal inflammation QTL 32.890.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)174992015486533673Rat
2303580Gluco49Glucose level QTL 492blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)175004027186533673Rat
1354629Scl31Serum cholesterol level QTL 314.1blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)175089090860781592Rat
1354654Spl7Serum phospholipid level QTL 75.5blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)175089090860781592Rat
4889894Eae33Experimental allergic encephalomyelitis QTL 335.20.0001nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)175090909986022412Rat
2317053Aia25Adjuvant induced arthritis QTL 252.69joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)175090919660781426Rat

Markers in Region
AU048913  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21826,124,824 - 26,125,014 (+)MAPPERmRatBN7.2
mRatBN7.21751,295,090 - 51,296,033 (+)MAPPERmRatBN7.2
Rnor_6.01753,988,032 - 53,988,974NCBIRnor6.0
Rnor_6.01827,318,371 - 27,318,560NCBIRnor6.0
Rnor_5.01827,031,743 - 27,031,932UniSTSRnor5.0
Rnor_5.01751,681,693 - 51,682,636UniSTSRnor5.0
RGSC_v3.41759,490,301 - 59,491,243UniSTSRGSC3.4
RGSC_v3.41826,994,291 - 26,994,480UniSTSRGSC3.4
Celera1825,863,356 - 25,863,549UniSTS
Celera1747,302,843 - 47,303,785UniSTS
Cytogenetic Map17q12.1UniSTS
AA998918  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21751,334,948 - 51,335,140 (+)MAPPERmRatBN7.2
Rnor_6.01754,027,887 - 54,028,078NCBIRnor6.0
Rnor_5.01751,721,989 - 51,722,180UniSTSRnor5.0
RGSC_v3.41759,531,900 - 59,532,091UniSTSRGSC3.4
Celera1747,342,282 - 47,342,474UniSTS
RH 3.4 Map17535.29UniSTS
Cytogenetic Map17q12.1UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 39 57 41 19 41 2 2 74 35 38 11 2
Low 4 6 9 3 6
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001012161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006254015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008771736 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600614 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095910 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005495303 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005495304 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_361037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_361038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC114215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC079444 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC089833 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234296 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000293 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000040743   ⟹   ENSRNOP00000042689
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1751,290,202 - 51,336,088 (+)Ensembl
Rnor_6.0 Ensembl1753,983,182 - 54,029,027 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000079433   ⟹   ENSRNOP00000071747
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1751,290,699 - 51,336,089 (+)Ensembl
Rnor_6.0 Ensembl1753,988,541 - 54,029,027 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000111847   ⟹   ENSRNOP00000079636
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1751,297,493 - 51,336,089 (+)Ensembl
RefSeq Acc Id: NM_001012161   ⟹   NP_001012161
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21751,290,247 - 51,336,090 (+)NCBI
Rnor_6.01753,983,182 - 54,029,028 (+)NCBI
Rnor_5.01751,676,746 - 51,723,130 (+)NCBI
RGSC_v3.41759,485,451 - 59,533,041 (+)RGD
Celera1747,297,977 - 47,343,424 (+)RGD
Sequence:
RefSeq Acc Id: XM_006254015   ⟹   XP_006254077
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21751,290,143 - 51,336,090 (+)NCBI
Rnor_6.01753,983,126 - 54,029,028 (+)NCBI
Rnor_5.01751,676,746 - 51,723,130 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008771736   ⟹   XP_008769958
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21751,295,725 - 51,336,090 (+)NCBI
Rnor_6.01753,988,943 - 54,029,028 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017600614   ⟹   XP_017456103
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21751,290,601 - 51,336,090 (+)NCBI
Rnor_6.01753,983,611 - 54,029,028 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039095910   ⟹   XP_038951838
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21751,295,725 - 51,336,090 (+)NCBI
RefSeq Acc Id: XM_039095911   ⟹   XP_038951839
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21751,319,821 - 51,336,090 (+)NCBI
RefSeq Acc Id: XR_005495303
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21751,295,725 - 51,336,090 (+)NCBI
RefSeq Acc Id: XR_005495304
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21751,295,725 - 51,336,090 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001012161   ⟸   NM_001012161
- UniProtKB: Q5FVQ9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006254077   ⟸   XM_006254015
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_008769958   ⟸   XM_008771736
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017456103   ⟸   XM_017600614
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSRNOP00000071747   ⟸   ENSRNOT00000079433
RefSeq Acc Id: ENSRNOP00000042689   ⟸   ENSRNOT00000040743
RefSeq Acc Id: XP_038951838   ⟸   XM_039095910
- Peptide Label: isoform X2
- UniProtKB: A0A0G2K191 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951839   ⟸   XM_039095911
- Peptide Label: isoform X4
RefSeq Acc Id: ENSRNOP00000079636   ⟸   ENSRNOT00000111847
Protein Domains
CAP-Gly   LRRCT

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5FVQ9-F1-model_v2 AlphaFold Q5FVQ9 1-524 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700517
Promoter ID:EPDNEW_R11040
Type:initiation region
Name:Tbce_1
Description:tubulin folding cofactor E
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01753,983,159 - 53,983,219EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305533 AgrOrtholog
BioCyc Gene G2FUF-9063 BioCyc
Ensembl Genes ENSRNOG00000029667 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000042689 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000071747 ENTREZGENE
  ENSRNOP00000071747.1 UniProtKB/TrEMBL
  ENSRNOP00000079636.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000040743 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000079433 ENTREZGENE
  ENSRNOT00000079433.2 UniProtKB/TrEMBL
  ENSRNOT00000111847.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.30.190 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7325371 IMAGE-MGC_LOAD
InterPro CAP-Gly_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CAP-Gly_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TBCE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ubiquitin-like_dom UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ubiquitin_dom UniProtKB/Swiss-Prot
  Ubl_TBCE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:361255 UniProtKB/Swiss-Prot
MGC_CLONE MGC:108815 IMAGE-MGC_LOAD
NCBI Gene 361255 ENTREZGENE
PANTHER PTHR15140 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam CAP_GLY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ubiquitin_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tbce PhenoGen
PROSITE CAP_GLY_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CAP_GLY_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART CAP_GLY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54236 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF74924 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K191 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZRE1_RAT UniProtKB/TrEMBL
  Q5FVQ9 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-23 Tbce  tubulin folding cofactor E  Tbce  tubulin-specific chaperone e  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Tbce  tubulin-specific chaperone e  Tbce_predicted  tubulin-specific chaperone e (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Tbce_predicted  tubulin-specific chaperone e (predicted)      Symbol and Name status set to approved 70820 APPROVED