Cdk13 (cyclin-dependent kinase 13) - Rat Genome Database

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Gene: Cdk13 (cyclin-dependent kinase 13) Rattus norvegicus
Analyze
Symbol: Cdk13
Name: cyclin-dependent kinase 13
RGD ID: 1311226
Description: Predicted to enable RNA polymerase II CTD heptapeptide repeat kinase activity; cyclin binding activity; and protein kinase binding activity. Predicted to be involved in several processes, including alternative mRNA splicing, via spliceosome; hemopoiesis; and positive regulation of transcription elongation by RNA polymerase II. Predicted to act upstream of or within negative regulation of stem cell differentiation. Predicted to be located in Golgi apparatus; cytosol; and nuclear speck. Predicted to be part of cyclin K-CDK13 complex and cyclin/CDK positive transcription elongation factor complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in congenital heart defects, dysmorphic facial features, and intellectual developmental disorder; hepatocellular carcinoma; intellectual disability; and prostate carcinoma. Orthologous to human CDK13 (cyclin dependent kinase 13); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amitrole; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Cdc2l5; cell division cycle 2-like 5; cell division cycle 2-like 5 (cholinesterase-related cell division controller); cell division protein kinase 13; LOC306998
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81751,945,975 - 52,040,218 (+)NCBIGRCr8
mRatBN7.21747,251,145 - 47,344,675 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1747,251,163 - 47,341,721 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1750,448,558 - 50,539,106 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01754,451,453 - 54,542,000 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01748,553,419 - 48,643,938 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01749,833,194 - 49,922,932 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1749,833,400 - 49,921,550 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01747,889,843 - 47,979,627 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41755,146,130 - 55,235,545 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11755,071,862 - 55,237,672 (+)NCBI
Celera1743,336,076 - 43,426,801 (+)NCBICelera
Cytogenetic Map17q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Phenotypic and molecular characterisation of CDK13-related congenital heart defects, dysmorphic facial features and intellectual developmental disorders. Bostwick BL, etal., Genome Med. 2017 Aug 14;9(1):73. doi: 10.1186/s13073-017-0463-8.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Heterozygous mutations affecting the protein kinase domain of CDK13 cause a syndromic form of developmental delay and intellectual disability. Hamilton MJ, etal., J Med Genet. 2018 Jan;55(1):28-38. doi: 10.1136/jmedgenet-2017-104620. Epub 2017 Oct 11.
5. Frequent amplification of CENPF, GMNN and CDK13 genes in hepatocellular carcinomas. Kim HE, etal., PLoS One. 2012;7(8):e43223. doi: 10.1371/journal.pone.0043223. Epub 2012 Aug 13.
6. Expression of CDK13 Was Associated with Prognosis and Expression of HIF-1α and beclin1 in Breast Cancer Patients. Lu XL, etal., J Invest Surg. 2022 Feb;35(2):442-447. doi: 10.1080/08941939.2020.1852344. Epub 2020 Dec 8.
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. CDK13 upregulation-induced formation of the positive feedback loop among circCDK13, miR-212-5p/miR-449a and E2F5 contributes to prostate carcinogenesis. Qi JC, etal., J Exp Clin Cancer Res. 2021 Jan 4;40(1):2. doi: 10.1186/s13046-020-01814-5.
9. GOA pipeline RGD automated data pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Distinct genetic architectures for syndromic and nonsyndromic congenital heart defects identified by exome sequencing. Sifrim A, etal., Nat Genet. 2016 Sep;48(9):1060-5. doi: 10.1038/ng.3627. Epub 2016 Aug 1.
13. Redefining the phenotypic spectrum of de novo heterozygous CDK13 variants: Three patients without cardiac defects. Uehara T, etal., Eur J Med Genet. 2018 May;61(5):243-247. doi: 10.1016/j.ejmg.2017.12.004. Epub 2017 Dec 6.
14. De novo variants in CDK13 associated with syndromic ID/DD: Molecular and clinical delineation of 15 individuals and a further review. van den Akker WMR, etal., Clin Genet. 2018 May;93(5):1000-1007. doi: 10.1111/cge.13225.
Additional References at PubMed
PMID:1731328   PMID:12477932   PMID:16721827   PMID:17261272   PMID:20952539   PMID:22012619   PMID:22547058   PMID:22664934   PMID:22681889  


Genomics

Comparative Map Data
Cdk13
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81751,945,975 - 52,040,218 (+)NCBIGRCr8
mRatBN7.21747,251,145 - 47,344,675 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1747,251,163 - 47,341,721 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1750,448,558 - 50,539,106 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01754,451,453 - 54,542,000 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01748,553,419 - 48,643,938 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01749,833,194 - 49,922,932 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1749,833,400 - 49,921,550 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01747,889,843 - 47,979,627 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41755,146,130 - 55,235,545 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11755,071,862 - 55,237,672 (+)NCBI
Celera1743,336,076 - 43,426,801 (+)NCBICelera
Cytogenetic Map17q11NCBI
CDK13
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38739,950,256 - 40,099,580 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl739,950,121 - 40,099,580 (+)EnsemblGRCh38hg38GRCh38
GRCh37739,989,855 - 40,139,179 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36739,956,484 - 40,101,679 (+)NCBINCBI36Build 36hg18NCBI36
Build 34739,763,348 - 39,908,385NCBI
Celera739,978,186 - 40,124,932 (+)NCBICelera
Cytogenetic Map7p14.1NCBI
HuRef739,873,916 - 40,020,642 (+)NCBIHuRef
CHM1_1739,992,473 - 40,139,235 (+)NCBICHM1_1
T2T-CHM13v2.0740,107,756 - 40,257,030 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2740,028,472 - 40,175,171 (+)NCBI
Cdk13
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391317,885,309 - 17,979,960 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1317,884,900 - 17,979,682 (-)EnsemblGRCm39 Ensembl
GRCm381317,711,676 - 17,805,212 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1317,710,315 - 17,805,097 (-)EnsemblGRCm38mm10GRCm38
MGSCv371317,807,796 - 17,896,931 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361317,500,876 - 17,590,239 (-)NCBIMGSCv36mm8
Celera1318,019,147 - 18,109,011 (-)NCBICelera
Cytogenetic Map13A2NCBI
cM Map136.05NCBI
Cdk13
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554603,590,854 - 3,701,148 (-)NCBIChiLan1.0ChiLan1.0
CDK13
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2648,337,077 - 48,483,741 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1796,663,417 - 96,808,867 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0744,138,345 - 44,285,606 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1744,177,940 - 44,324,319 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl744,177,204 - 44,324,683 (-)Ensemblpanpan1.1panPan2
CDK13
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1189,801,350 - 9,920,401 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl189,803,535 - 9,920,281 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha189,647,410 - 9,768,703 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0189,847,718 - 9,969,056 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl189,851,883 - 10,014,941 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1189,825,425 - 9,946,650 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0189,795,209 - 9,922,569 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0189,909,730 - 10,031,244 (-)NCBIUU_Cfam_GSD_1.0
Cdk13
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511896,084,330 - 96,178,160 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647815,296,055 - 15,388,309 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647815,296,055 - 15,387,749 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDK13
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1854,310,324 - 54,430,786 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11854,310,311 - 54,430,060 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21859,602,083 - 59,696,059 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CDK13
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12118,551,273 - 18,688,889 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2118,553,446 - 18,688,525 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660623,715,053 - 3,852,971 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cdk13
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474021,105,212 - 21,202,111 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474021,100,780 - 21,202,147 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cdk13
152 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:199
Count of miRNA genes:131
Interacting mature miRNAs:153
Transcripts:ENSRNOT00000018431
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631497Bp98Blood pressure QTL 983.66arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)174135465160463643Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
1358295Aocep1Aortic cell protein QTL 16.17e-07thoracic aorta cellular protein amount (VT:0010598)aortic cell percentage174099000585990005Rat
1354640Scl32Serum cholesterol level QTL 325.4blood HDL cholesterol amount (VT:0000184)blood high density lipoprotein cholesterol level (CMO:0000052)171578159260781592Rat
152023626Bp403Blood pressure QTL 4033.86arterial blood pressure trait (VT:2000000)172393042179524188Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)173747984782479847Rat
9590107Sffal7Serum free fatty acids level QTL 74.810.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)172840914773409147Rat
2302377Scl61Serum cholesterol level QTL 614.36blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)172738994653481766Rat
70157Niddm32Non-insulin dependent diabetes mellitus QTL 324.34blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)172245492450909196Rat
724549Niddm56Non-insulin dependent diabetes mellitus QTL 560.03blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)173199078476990784Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
1598871Memor5Memory QTL 55.3exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)174054004180387013Rat
1354628Stl13Serum triglyceride level QTL 133.8blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)172129303960781592Rat
1581512Cm55Cardiac mass QTL 552.80.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172702794956836890Rat
10054088Scort28Serum corticosterone level QTL 282.040.0102blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17452803849528038Rat
1354630Cm34Cardiac mass QTL 348.7heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)17429913069599340Rat
61394Bp8Blood pressure QTL 82.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172308056759555013Rat
1559055Bp278Blood pressure QTL 2780.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318468653184Rat
10450503Bp386Blood pressure QTL 3860.28arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)173136839162109574Rat
152025238Slep14Serum leptin concentration QTL 144.62blood leptin amount (VT:0005667)172418489079524188Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)17429913069599340Rat
2313854Bp343Blood pressure QTL 3433.9life span trait (VT:0005372)age at time of death (CMO:0001193)173199078450909196Rat
2317054Aia12Adjuvant induced arthritis QTL 124.24joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)173828150983281509Rat
1354635Bp245Blood pressure QTL 2456arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)174207316069599340Rat
1331765Hrtrt15Heart rate QTL 154.094heart pumping trait (VT:2000009)heart rate (CMO:0000002)171533061355836425Rat
8552928Pigfal9Plasma insulin-like growth factor 1 level QTL 99blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)172840914773409147Rat
1300148Bp192Blood pressure QTL 1923.47arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)173455084373951021Rat
2317060Aia26Adjuvant induced arthritis QTL 263.22joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)173828150983281509Rat
2303627Vencon8Ventilatory control QTL 80.001respiration trait (VT:0001943)tidal volume (CMO:0000222)17452803849528038Rat
12903980Cm120Cardiac mass QTL 1200.002heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)172365318468653184Rat
12903981Am17Aortic mass QTL 170.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)172365318468653184Rat
4889955Bss93Bone structure and strength QTL 934.4tibia size trait (VT:0100001)tibia cortical bone volume to tibia total bone volume ratio (CMO:0001727)172702794960463643Rat
2303561Bw91Body weight QTL 912body mass (VT:0001259)body weight (CMO:0000012)17886846253868462Rat
12903982Kidm70Kidney mass QTL 700.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)172365318470974005Rat
12903978Cm118Cardiac mass QTL 1180.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)172365318468653184Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)173136839173951021Rat
12903979Cm119Cardiac mass QTL 1190.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172365318468653184Rat
1354619Bp242Blood pressure QTL 2426.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172459934069599340Rat
1354596Bw32Body weight QTL 324.5body mass (VT:0001259)body weight (CMO:0000012)17429913060781592Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat
152023740Bp406Blood pressure QTL 4066.06arterial blood pressure trait (VT:2000000)172393042179524188Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173199078481292925Rat
7488966Bp370Blood pressure QTL 3700.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318457246843Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17160781592Rat
152023737Bp405Blood pressure QTL 4055.06arterial blood pressure trait (VT:2000000)2393042179524188Rat
1354659Scl68Serum cholesterol level QTL 683.9blood VLDL cholesterol amount (VT:0005144)blood very low density lipoprotein cholesterol level (CMO:0000648)171578159260781592Rat
152023736Bp404Blood pressure QTL 4043.78arterial blood pressure trait (VT:2000000)172393042179524188Rat
724528Uae4Urinary albumin excretion QTL 44.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)173583708569599340Rat

Markers in Region
D17Rat74  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21747,220,193 - 47,220,440 (+)MAPPERmRatBN7.2
Rnor_6.01749,802,453 - 49,802,699NCBIRnor6.0
Rnor_5.01747,859,089 - 47,859,335UniSTSRnor5.0
RGSC_v3.41755,109,994 - 55,110,241RGDRGSC3.4
RGSC_v3.41755,109,995 - 55,110,241UniSTSRGSC3.4
RGSC_v3.11755,112,835 - 55,113,082RGD
Celera1743,305,192 - 43,305,438UniSTS
SHRSP x BN Map1730.3699UniSTS
SHRSP x BN Map1730.3699RGD
FHH x ACI Map1735.5899RGD
Cytogenetic Map17q12.1UniSTS
RH132491  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21747,330,420 - 47,330,600 (+)MAPPERmRatBN7.2
Rnor_6.01749,911,632 - 49,911,811NCBIRnor6.0
Rnor_5.01747,968,327 - 47,968,506UniSTSRnor5.0
RGSC_v3.41755,224,912 - 55,225,091UniSTSRGSC3.4
Celera1743,415,501 - 43,415,680UniSTS
RH 3.4 Map17474.3UniSTS
Cytogenetic Map17q12.1UniSTS
RH139622  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21747,340,451 - 47,340,658 (+)MAPPERmRatBN7.2
Rnor_6.01749,921,663 - 49,921,869NCBIRnor6.0
Rnor_5.01747,978,358 - 47,978,564UniSTSRnor5.0
RGSC_v3.41755,234,944 - 55,235,150UniSTSRGSC3.4
Celera1743,425,532 - 43,425,738UniSTS
RH 3.4 Map17476.49UniSTS
Cytogenetic Map17q12.1UniSTS
CDC2L5_3913  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21747,340,187 - 47,341,074 (+)MAPPERmRatBN7.2
Rnor_6.01749,921,399 - 49,922,285NCBIRnor6.0
Rnor_5.01747,978,094 - 47,978,980UniSTSRnor5.0
RGSC_v3.41755,234,680 - 55,235,566UniSTSRGSC3.4
Celera1743,425,268 - 43,426,154UniSTS
Cytogenetic Map17q12.1UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000018431   ⟹   ENSRNOP00000018431
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1747,251,163 - 47,341,721 (+)Ensembl
Rnor_6.0 Ensembl1749,833,400 - 49,921,550 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000107948   ⟹   ENSRNOP00000091047
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1747,251,163 - 47,341,721 (+)Ensembl
RefSeq Acc Id: NM_001271295   ⟹   NP_001258224
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81751,946,701 - 52,037,257 (+)NCBI
mRatBN7.21747,251,163 - 47,341,721 (+)NCBI
Rnor_6.01749,833,194 - 49,922,932 (+)NCBI
Rnor_5.01747,889,843 - 47,979,627 (+)NCBI
Celera1743,336,076 - 43,426,801 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001271296   ⟹   NP_001258225
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81751,946,701 - 52,037,257 (+)NCBI
mRatBN7.21747,251,163 - 47,341,721 (+)NCBI
Rnor_6.01749,833,194 - 49,922,932 (+)NCBI
Rnor_5.01747,889,843 - 47,979,627 (+)NCBI
Celera1743,336,076 - 43,426,801 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039095721   ⟹   XP_038951649
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81751,945,975 - 52,040,218 (+)NCBI
mRatBN7.21747,251,145 - 47,344,675 (+)NCBI
RefSeq Acc Id: XM_039095722   ⟹   XP_038951650
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81751,945,975 - 52,040,218 (+)NCBI
mRatBN7.21747,251,145 - 47,344,675 (+)NCBI
RefSeq Acc Id: XM_039095723   ⟹   XP_038951651
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81751,945,975 - 52,004,532 (+)NCBI
mRatBN7.21747,251,145 - 47,309,008 (+)NCBI
RefSeq Acc Id: XM_039095724   ⟹   XP_038951652
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81751,945,975 - 52,009,016 (+)NCBI
mRatBN7.21747,251,145 - 47,313,479 (+)NCBI
RefSeq Acc Id: XM_039095725   ⟹   XP_038951653
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81751,945,975 - 52,001,522 (+)NCBI
mRatBN7.21747,251,145 - 47,300,177 (+)NCBI
RefSeq Acc Id: XM_063276458   ⟹   XP_063132528
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81751,970,565 - 52,040,218 (+)NCBI
RefSeq Acc Id: NP_001258224   ⟸   NM_001271295
- Peptide Label: isoform 1
- UniProtKB: F1M1X9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001258225   ⟸   NM_001271296
- Peptide Label: isoform 2
- Sequence:
Ensembl Acc Id: ENSRNOP00000018431   ⟸   ENSRNOT00000018431
RefSeq Acc Id: XP_038951649   ⟸   XM_039095721
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AEX0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951650   ⟸   XM_039095722
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038951652   ⟸   XM_039095724
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038951651   ⟸   XM_039095723
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038951653   ⟸   XM_039095725
- Peptide Label: isoform X6
Ensembl Acc Id: ENSRNOP00000091047   ⟸   ENSRNOT00000107948
RefSeq Acc Id: XP_063132528   ⟸   XM_063276458
- Peptide Label: isoform X3
- UniProtKB: A6K9A4 (UniProtKB/TrEMBL)
Protein Domains
Protein kinase

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311226 AgrOrtholog
BioCyc Gene G2FUF-9113 BioCyc
Ensembl Genes ENSRNOG00000013620 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000018431.8 UniProtKB/TrEMBL
  ENSRNOT00000107948.1 UniProtKB/TrEMBL
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7382019 IMAGE-MGC_LOAD
InterPro CDK UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
MGC_CLONE MGC:116330 IMAGE-MGC_LOAD
NCBI Gene 306998 ENTREZGENE
PANTHER CELL DIVISION PROTEIN KINASE UniProtKB/TrEMBL
  CYCLIN-DEPENDENT KINASE 13 UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PhenoGen Cdk13 PhenoGen
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
RatGTEx ENSRNOG00000013620 RatGTEx
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A8I6AEX0 ENTREZGENE, UniProtKB/TrEMBL
  A6K9A4 ENTREZGENE, UniProtKB/TrEMBL
  F1M1X9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-07-29 Cdk13  cyclin-dependent kinase 13  Cdc2l5  cell division cycle 2-like 5 (cholinesterase-related cell division controller)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Cdc2l5  cell division cycle 2-like 5 (cholinesterase-related cell division controller)  Cdc2l5_predicted  cell division cycle 2-like 5 (cholinesterase-related cell division controller) (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Cdc2l5_predicted  cell division cycle 2-like 5 (cholinesterase-related cell division controller) (predicted)      Symbol and Name status set to approved 70820 APPROVED