Fbh1 (F-box DNA helicase 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Fbh1 (F-box DNA helicase 1) Rattus norvegicus
Analyze
Symbol: Fbh1
Name: F-box DNA helicase 1
RGD ID: 1306298
Description: Predicted to enable ATP-dependent activity, acting on DNA and DNA binding activity. Predicted to be involved in DNA metabolic process; negative regulation of double-strand break repair via homologous recombination; and protein ubiquitination. Predicted to act upstream of or within several processes, including DNA catabolic process; positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage; and response to intra-S DNA damage checkpoint signaling. Predicted to be located in chromatin. Predicted to be part of SCF ubiquitin ligase complex. Predicted to be active in nucleus. Orthologous to human FBH1 (F-box DNA helicase 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: F-box only protein 18; F-box protein, helicase, 18; Fbxo18; LOC291293
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81771,659,351 - 71,697,431 (+)NCBIGRCr8
mRatBN7.21766,749,506 - 66,787,590 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1766,749,534 - 66,787,590 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1770,234,900 - 70,273,108 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01774,063,717 - 74,101,925 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01768,106,715 - 68,144,923 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01770,399,093 - 70,437,151 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1770,399,049 - 70,437,144 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01772,103,236 - 72,141,153 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41777,945,025 - 77,982,314 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11777,955,040 - 77,992,878 (+)NCBI
Celera1766,254,767 - 66,292,706 (+)NCBICelera
Cytogenetic Map17q12.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11956208   PMID:19736316   PMID:23319600   PMID:23361013   PMID:23393192   PMID:24108124   PMID:25585578  


Genomics

Comparative Map Data
Fbh1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81771,659,351 - 71,697,431 (+)NCBIGRCr8
mRatBN7.21766,749,506 - 66,787,590 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1766,749,534 - 66,787,590 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1770,234,900 - 70,273,108 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01774,063,717 - 74,101,925 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01768,106,715 - 68,144,923 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01770,399,093 - 70,437,151 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1770,399,049 - 70,437,144 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01772,103,236 - 72,141,153 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41777,945,025 - 77,982,314 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11777,955,040 - 77,992,878 (+)NCBI
Celera1766,254,767 - 66,292,706 (+)NCBICelera
Cytogenetic Map17q12.2NCBI
FBH1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38105,889,572 - 5,937,593 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl105,890,203 - 5,937,594 (+)EnsemblGRCh38hg38GRCh38
GRCh37105,931,535 - 5,979,556 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36105,972,220 - 6,019,562 (+)NCBINCBI36Build 36hg18NCBI36
Celera105,862,606 - 5,909,945 (+)NCBICelera
Cytogenetic Map10p15.1NCBI
HuRef105,858,336 - 5,906,371 (+)NCBIHuRef
CHM1_1105,931,521 - 5,979,540 (+)NCBICHM1_1
T2T-CHM13v2.0105,890,100 - 5,938,280 (+)NCBIT2T-CHM13v2.0
Fbh1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39211,747,384 - 11,782,396 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl211,747,384 - 11,782,393 (-)EnsemblGRCm39 Ensembl
GRCm38211,742,573 - 11,777,585 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl211,742,573 - 11,777,582 (-)EnsemblGRCm38mm10GRCm38
MGSCv37211,664,200 - 11,699,154 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36211,660,426 - 11,695,380 (-)NCBIMGSCv36mm8
Celera211,660,214 - 11,695,055 (-)NCBICelera
Cytogenetic Map2A1NCBI
cM Map29.01NCBI
Fbh1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542122,535,777 - 22,579,965 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542122,535,777 - 22,579,965 (+)NCBIChiLan1.0ChiLan1.0
FBH1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2818,443,816 - 18,491,260 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11018,449,139 - 18,496,583 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0105,931,389 - 5,978,844 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1105,915,696 - 5,962,778 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl105,915,713 - 5,962,778 (+)Ensemblpanpan1.1panPan2
FBH1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1230,047,994 - 30,095,761 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl230,048,567 - 30,095,696 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha227,078,633 - 27,126,242 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0230,429,230 - 30,476,841 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl230,429,696 - 30,477,995 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1227,526,051 - 27,573,654 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0228,362,332 - 28,409,932 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0229,080,666 - 29,128,279 (-)NCBIUU_Cfam_GSD_1.0
Fbh1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934432,470,555 - 32,524,769 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364848,635,753 - 8,689,971 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364848,635,752 - 8,689,949 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FBH1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1065,060,312 - 65,108,379 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11065,060,714 - 65,108,975 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21071,185,904 - 71,224,589 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FBH1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.196,001,071 - 6,047,512 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl96,013,908 - 6,047,753 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605111,301,589 - 11,351,058 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fbh1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624775788,463 - 837,524 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624775788,388 - 844,968 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Fbh1
157 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:225
Count of miRNA genes:161
Interacting mature miRNAs:182
Transcripts:ENSRNOT00000025228
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
70210Cm15Cardiac mass QTL 156.5heart right ventricle mass (VT:0007033)heart right ventricle wet weight (CMO:0000072)175724672370156904Rat
1358295Aocep1Aortic cell protein QTL 16.17e-07thoracic aorta cellular protein amount (VT:0010598)aortic cell percentage174099000585990005Rat
152023626Bp403Blood pressure QTL 4033.86arterial blood pressure trait (VT:2000000)172393042179524188Rat
7411575Bw140Body weight QTL 14030.20.001body mass (VT:0001259)body weight gain (CMO:0000420)174856093586533673Rat
631502Cm26Cardiac mass QTL 263.71heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)176570358081153923Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)173747984782479847Rat
1354588Bvd4Brain ventricular dilatation QTL 45.310.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)175349882882479847Rat
7411577Bw141Body weight QTL 1410.001body mass (VT:0001259)body weight gain (CMO:0000420)176261951686533673Rat
9590107Sffal7Serum free fatty acids level QTL 74.810.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)172840914773409147Rat
2317038Ginf3Gastrointestinal inflammation QTL 32.890.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)174992015486533673Rat
724549Niddm56Non-insulin dependent diabetes mellitus QTL 560.03blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)173199078476990784Rat
1598871Memor5Memory QTL 55.3exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)174054004180387013Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
1354630Cm34Cardiac mass QTL 348.7heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)17429913069599340Rat
1600398Edcs5Endometrial carcinoma susceptibility QTL 52.2uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)175724672370852846Rat
2317045Aia11Adjuvant induced arthritis QTL 114.06joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)176078142686533673Rat
1559055Bp278Blood pressure QTL 2780.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318468653184Rat
152025238Slep14Serum leptin concentration QTL 144.62blood leptin amount (VT:0005667)172418489079524188Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)17429913069599340Rat
2317054Aia12Adjuvant induced arthritis QTL 124.24joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)173828150983281509Rat
1354635Bp245Blood pressure QTL 2456arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)174207316069599340Rat
8694181Bw151Body weight QTL 1514.360.001body mass (VT:0001259)body weight gain (CMO:0000420)174856093586533673Rat
8552928Pigfal9Plasma insulin-like growth factor 1 level QTL 99blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)172840914773409147Rat
1300148Bp192Blood pressure QTL 1923.47arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)173455084373951021Rat
2317060Aia26Adjuvant induced arthritis QTL 263.22joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)173828150983281509Rat
12903980Cm120Cardiac mass QTL 1200.002heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)172365318468653184Rat
12903981Am17Aortic mass QTL 170.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)172365318468653184Rat
12903982Kidm70Kidney mass QTL 700.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)172365318470974005Rat
4889894Eae33Experimental allergic encephalomyelitis QTL 335.20.0001nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)175090909986022412Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)173136839173951021Rat
12903978Cm118Cardiac mass QTL 1180.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)172365318468653184Rat
1354619Bp242Blood pressure QTL 2426.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172459934069599340Rat
12903979Cm119Cardiac mass QTL 1190.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172365318468653184Rat
1300131Bp193Blood pressure QTL 1933.3arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)176364000973951021Rat
7488963Bp369Blood pressure QTL 3690.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)175900564977910000Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173199078481292925Rat
152023740Bp406Blood pressure QTL 4066.06arterial blood pressure trait (VT:2000000)172393042179524188Rat
152023737Bp405Blood pressure QTL 4055.06arterial blood pressure trait (VT:2000000)2393042179524188Rat
152023736Bp404Blood pressure QTL 4043.78arterial blood pressure trait (VT:2000000)172393042179524188Rat
724528Uae4Urinary albumin excretion QTL 44.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)173583708569599340Rat
2302365Gluco40Glucose level QTL 404.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)175724684382046127Rat
2303580Gluco49Glucose level QTL 492blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)175004027186533673Rat

Markers in Region
RH133366  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21766,787,310 - 66,787,493 (+)MAPPERmRatBN7.2
Rnor_6.01770,436,872 - 70,437,054NCBIRnor6.0
Rnor_5.01772,140,874 - 72,141,056UniSTSRnor5.0
RGSC_v3.41777,982,035 - 77,982,217UniSTSRGSC3.4
Celera1766,292,427 - 66,292,609UniSTS
Cytogenetic Map17q12.3UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000025228   ⟹   ENSRNOP00000025228
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1766,749,534 - 66,787,590 (+)Ensembl
Rnor_6.0 Ensembl1770,399,049 - 70,437,144 (+)Ensembl
RefSeq Acc Id: NM_001106119   ⟹   NP_001099589
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81771,659,378 - 71,697,431 (+)NCBI
mRatBN7.21766,749,534 - 66,787,590 (+)NCBI
Rnor_6.01770,399,102 - 70,437,151 (+)NCBI
Rnor_5.01772,103,236 - 72,141,153 (+)NCBI
RGSC_v3.41777,945,025 - 77,982,314 (+)RGD
Celera1766,254,767 - 66,292,706 (+)RGD
Sequence:
RefSeq Acc Id: XM_039095534   ⟹   XP_038951462
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81771,659,554 - 71,697,426 (+)NCBI
mRatBN7.21766,749,705 - 66,787,590 (+)NCBI
RefSeq Acc Id: XM_039095536   ⟹   XP_038951464
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81771,659,411 - 71,697,426 (+)NCBI
mRatBN7.21766,749,554 - 66,787,590 (+)NCBI
RefSeq Acc Id: XM_039095537   ⟹   XP_038951465
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81771,659,401 - 71,697,426 (+)NCBI
mRatBN7.21766,749,552 - 66,787,590 (+)NCBI
RefSeq Acc Id: XM_063276238   ⟹   XP_063132308
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81771,669,640 - 71,697,426 (+)NCBI
RefSeq Acc Id: XM_063276239   ⟹   XP_063132309
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81771,659,351 - 71,689,385 (+)NCBI
RefSeq Acc Id: NP_001099589   ⟸   NM_001106119
- UniProtKB: F1M298 (UniProtKB/TrEMBL),   A6JLR6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000025228   ⟸   ENSRNOT00000025228
RefSeq Acc Id: XP_038951465   ⟸   XM_039095537
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038951464   ⟸   XM_039095536
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038951462   ⟸   XM_039095534
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063132309   ⟸   XM_063276239
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063132308   ⟸   XM_063276238
- Peptide Label: isoform X1
Protein Domains
F-box

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1M298-F1-model_v2 AlphaFold F1M298 1-1042 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700555
Promoter ID:EPDNEW_R11078
Type:initiation region
Name:Fbxo18_1
Description:F-box protein, helicase, 18
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01770,399,117 - 70,399,177EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306298 AgrOrtholog
BioCyc Gene G2FUF-8802 BioCyc
Ensembl Genes ENSRNOG00000018549 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000025228.8 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1280.50 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro DNA_helicase_UvrD-like_C UniProtKB/TrEMBL
  DNA_helicase_UvrD/REP UniProtKB/TrEMBL
  F-box_dom_cyclin-like UniProtKB/TrEMBL
  F-box_dom_like UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  UvrD-like_ATP-bd UniProtKB/TrEMBL
KEGG Report rno:291293 UniProtKB/TrEMBL
NCBI Gene 291293 ENTREZGENE
PANTHER F-BOX DNA HELICASE 1 UniProtKB/TrEMBL
  UvrD_helicase UniProtKB/TrEMBL
Pfam F-box-like UniProtKB/TrEMBL
  UvrD-helicase UniProtKB/TrEMBL
  UvrD_C UniProtKB/TrEMBL
PhenoGen Fbh1 PhenoGen
PROSITE FBOX UniProtKB/TrEMBL
RatGTEx ENSRNOG00000018549 RatGTEx
Superfamily-SCOP F-box_dom_Skp2-like UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A6JLR6 ENTREZGENE, UniProtKB/TrEMBL
  F1M298 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-03-26 Fbh1  F-box DNA helicase 1  Fbxo18  F-box protein, helicase, 18  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-16 Fbxo18  F-box protein, helicase, 18  Fbxo18  F-box only protein 18  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Fbxo18  F-box only protein 18   Fbxo18_predicted  F-box only protein 18 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Fbxo18_predicted  F-box only protein 18 (predicted)      Symbol and Name status set to approved 70820 APPROVED