Armh2 (armadillo-like helical domain containing 2) - Rat Genome Database

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Gene: Armh2 (armadillo-like helical domain containing 2) Rattus norvegicus
Analyze
Symbol: Armh2
Name: armadillo-like helical domain containing 2
RGD ID: 7707229
Description: Orthologous to human ARMH2 (armadillo like helical domain containing 2); INTERACTS WITH aristolochic acid A (ortholog); sodium arsenite (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: armadillo-like helical domain-containing protein 2; LOC102548126; uncharacterized LOC102548126; uncharacterized protein C6orf229 homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81740,745,342 - 40,749,947 (-)NCBIGRCr8
mRatBN7.21740,317,319 - 40,321,924 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1740,317,331 - 40,321,937 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1740,385,217 - 40,389,803 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01741,989,257 - 41,993,843 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01740,272,492 - 40,277,083 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01742,317,899 - 42,323,589 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01744,185,493 - 44,191,081 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1739,954,033 - 39,959,723 (-)NCBICelera
Cytogenetic Map17p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
Armh2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81740,745,342 - 40,749,947 (-)NCBIGRCr8
mRatBN7.21740,317,319 - 40,321,924 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1740,317,331 - 40,321,937 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1740,385,217 - 40,389,803 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01741,989,257 - 41,993,843 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01740,272,492 - 40,277,083 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01742,317,899 - 42,323,589 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01744,185,493 - 44,191,081 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1739,954,033 - 39,959,723 (-)NCBICelera
Cytogenetic Map17p11NCBI
ARMH2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38624,797,335 - 24,798,917 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl624,797,335 - 24,798,917 (-)EnsemblGRCh38hg38GRCh38
GRCh37624,797,563 - 24,799,145 (-)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map6p22.3NCBI
HuRef624,747,000 - 24,748,977 (-)NCBIHuRef
CHM1_1624,801,672 - 24,803,649 (-)NCBICHM1_1
T2T-CHM13v2.0624,668,473 - 24,670,055 (-)NCBIT2T-CHM13v2.0
Armh2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391324,918,006 - 24,930,577 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1324,925,215 - 24,930,575 (+)EnsemblGRCm39 Ensembl
GRCm381324,734,023 - 24,746,594 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1324,741,232 - 24,746,592 (+)EnsemblGRCm38mm10GRCm38
MGSCv371324,833,089 - 24,838,459 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361324,748,679 - 24,754,057 (+)NCBIMGSCv36mm8
Celera1324,971,876 - 24,977,255 (+)NCBICelera
Cytogenetic Map13A3.1NCBI
cM Map1310.63NCBI
Armh2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554832,270,940 - 2,274,025 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554832,271,132 - 2,273,986 (+)NCBIChiLan1.0ChiLan1.0
ARMH2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2539,448,695 - 39,450,346 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1635,448,252 - 35,449,903 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0624,635,315 - 24,636,866 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1624,966,457 - 24,968,033 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl624,966,457 - 24,968,033 (-)Ensemblpanpan1.1panPan2
ARMH2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13522,816,634 - 22,819,325 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3522,816,723 - 22,819,242 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3522,784,567 - 22,787,245 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03522,939,013 - 22,941,691 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3522,939,006 - 22,941,621 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13522,744,051 - 22,746,729 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03522,791,893 - 22,794,572 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03524,228,164 - 24,230,842 (-)NCBIUU_Cfam_GSD_1.0
Armh2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049462,586,955 - 2,588,421 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366711,033,147 - 1,034,665 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366711,033,182 - 1,034,899 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARMH2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl719,598,807 - 19,602,084 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1719,598,328 - 19,603,533 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2720,752,375 - 20,755,341 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ARMH2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11747,446,311 - 47,450,767 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1747,446,807 - 47,450,669 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604424,730,194 - 24,734,196 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Armh2
18 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
2300002Iddm36Insulin dependent diabetes mellitus QTL 361.98blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)17999128640540197Rat
1354640Scl32Serum cholesterol level QTL 325.4blood HDL cholesterol amount (VT:0000184)blood high density lipoprotein cholesterol level (CMO:0000052)171578159260781592Rat
152023626Bp403Blood pressure QTL 4033.86arterial blood pressure trait (VT:2000000)172393042179524188Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)173747984782479847Rat
9590107Sffal7Serum free fatty acids level QTL 74.810.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)172840914773409147Rat
2302377Scl61Serum cholesterol level QTL 614.36blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)172738994653481766Rat
70157Niddm32Non-insulin dependent diabetes mellitus QTL 324.34blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)172245492450909196Rat
724549Niddm56Non-insulin dependent diabetes mellitus QTL 560.03blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)173199078476990784Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
1354628Stl13Serum triglyceride level QTL 133.8blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)172129303960781592Rat
1581512Cm55Cardiac mass QTL 552.80.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172702794956836890Rat
10054088Scort28Serum corticosterone level QTL 282.040.0102blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17452803849528038Rat
1354630Cm34Cardiac mass QTL 348.7heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)17429913069599340Rat
61394Bp8Blood pressure QTL 82.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172308056759555013Rat
1559055Bp278Blood pressure QTL 2780.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318468653184Rat
10450503Bp386Blood pressure QTL 3860.28arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)173136839162109574Rat
152025238Slep14Serum leptin concentration QTL 144.62blood leptin amount (VT:0005667)172418489079524188Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)17429913069599340Rat
2313854Bp343Blood pressure QTL 3433.9life span trait (VT:0005372)age at time of death (CMO:0001193)173199078450909196Rat
2317054Aia12Adjuvant induced arthritis QTL 124.24joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)173828150983281509Rat
1331765Hrtrt15Heart rate QTL 154.094heart pumping trait (VT:2000009)heart rate (CMO:0000002)171533061355836425Rat
8552928Pigfal9Plasma insulin-like growth factor 1 level QTL 99blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)172840914773409147Rat
1300148Bp192Blood pressure QTL 1923.47arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)173455084373951021Rat
2317060Aia26Adjuvant induced arthritis QTL 263.22joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)173828150983281509Rat
2303627Vencon8Ventilatory control QTL 80.001respiration trait (VT:0001943)tidal volume (CMO:0000222)17452803849528038Rat
12903980Cm120Cardiac mass QTL 1200.002heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)172365318468653184Rat
12903981Am17Aortic mass QTL 170.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)172365318468653184Rat
4889955Bss93Bone structure and strength QTL 934.4tibia size trait (VT:0100001)tibia cortical bone volume to tibia total bone volume ratio (CMO:0001727)172702794960463643Rat
2303561Bw91Body weight QTL 912body mass (VT:0001259)body weight (CMO:0000012)17886846253868462Rat
12903982Kidm70Kidney mass QTL 700.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)172365318470974005Rat
12903978Cm118Cardiac mass QTL 1180.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)172365318468653184Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)173136839173951021Rat
12903979Cm119Cardiac mass QTL 1190.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172365318468653184Rat
1354619Bp242Blood pressure QTL 2426.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172459934069599340Rat
1354596Bw32Body weight QTL 324.5body mass (VT:0001259)body weight (CMO:0000012)17429913060781592Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat
152023740Bp406Blood pressure QTL 4066.06arterial blood pressure trait (VT:2000000)172393042179524188Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173199078481292925Rat
7488966Bp370Blood pressure QTL 3700.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318457246843Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17160781592Rat
152023737Bp405Blood pressure QTL 4055.06arterial blood pressure trait (VT:2000000)2393042179524188Rat
1354659Scl68Serum cholesterol level QTL 683.9blood VLDL cholesterol amount (VT:0005144)blood very low density lipoprotein cholesterol level (CMO:0000648)171578159260781592Rat
152023736Bp404Blood pressure QTL 4043.78arterial blood pressure trait (VT:2000000)172393042179524188Rat
724528Uae4Urinary albumin excretion QTL 44.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)173583708569599340Rat


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSRNOT00000114703   ⟹   ENSRNOP00000095241
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1740,317,331 - 40,321,937 (-)Ensembl
RefSeq Acc Id: NM_001400849   ⟹   NP_001387778
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81740,745,342 - 40,749,947 (-)NCBI
mRatBN7.21740,317,319 - 40,321,924 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001387778 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL86505 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000095241.1
Ensembl Acc Id: ENSRNOP00000095241   ⟸   ENSRNOT00000114703
RefSeq Acc Id: NP_001387778   ⟸   NM_001400849
- UniProtKB: A0A8I6AT44 (UniProtKB/TrEMBL),   A6KLG0 (UniProtKB/TrEMBL)

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:7707229 AgrOrtholog
BioCyc Gene G2FUF-9419 BioCyc
Ensembl Genes ENSRNOG00000064812 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000114703.1 UniProtKB/TrEMBL
InterPro ARM-type_fold UniProtKB/TrEMBL
  ARMH2 UniProtKB/TrEMBL
NCBI Gene LOC102548126 ENTREZGENE
PANTHER ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 2 UniProtKB/TrEMBL
  PTHR37679 UniProtKB/TrEMBL
Pfam DUF5584 UniProtKB/TrEMBL
PhenoGen Armh2 PhenoGen
RatGTEx ENSRNOG00000064812 RatGTEx
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
UniProt A0A8I6AT44 ENTREZGENE, UniProtKB/TrEMBL
  A6KLG0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-02 Armh2  armadillo-like helical domain containing 2  Armh2  armadillo-like helical domain containing 2  Data merged from RGD:149736477 737654 PROVISIONAL
2021-08-09 Armh2  armadillo-like helical domain containing 2      Symbol and Name status set to provisional 45752 PROVISIONAL
2018-02-12 Armh2  armadillo-like helical domain containing 2  LOC102548126  uncharacterized LOC102548126  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-12-18 LOC102548126  uncharacterized LOC102548126      Symbol and Name status set to provisional 70820 PROVISIONAL