H2ac23 (H2A clustered histone 23) - Rat Genome Database

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Gene: H2ac23 (H2A clustered histone 23) Rattus norvegicus
Analyze
No known orthologs.
Symbol: H2ac23 (Ensembl: Hist1h2anl1)
Name: H2A clustered histone 23 (Ensembl:histone cluster 1, H2an-like 1)
RGD ID: 1586722
Description: Predicted to enable DNA binding activity and protein heterodimerization activity.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: H2A clustered histone 13; H2ac13; histone H2A type 1; histone H2A type 1-B; histone H2A type 1-H; LOC684773; similar to histone 2a
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81741,960,723 - 41,961,309 (-)NCBIGRCr8
mRatBN7.21741,532,685 - 41,533,271 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1741,534,691 - 41,539,869 (+)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl1742,478,860 - 42,479,252 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01743,777,353 - 43,777,827 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1744,794,130 - 44,794,522 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1744,520,537 - 44,520,929 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1744,758,460 - 44,758,852 (+)EnsemblRnor6.0rn6Rnor6.0
Celera1741,163,599 - 41,164,207 (-)NCBICelera
Cytogenetic Map17p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
H2ac23Ratheterochromatin formation involved_inIBAPANTHER:PTN000604564 and SGD:S0000053721600115GO_REF:0000033GO_CentralGO_REF:0000033

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
H2ac23Ratchromosome located_inIEAUniProtKB-SubCell:SL-04681600115GO_REF:0000044UniProtGO_REF:0000044
H2ac23Ratchromosome located_inIEAUniProtKB-KW:KW-01581600115GO_REF:0000043UniProtGO_REF:0000043
H2ac23Ratnucleosome part_ofIEAInterPro:IPR0021191600115GO_REF:0000002InterProGO_REF:0000002
H2ac23Ratnucleosome part_ofIEAUniProtKB-KW:KW-05441600115GO_REF:0000043UniProtGO_REF:0000043
H2ac23Ratnucleosome part_ofIBAFB:FBgn0001197 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
H2ac23Ratnucleus is_active_inIBAFB:FBgn0001196 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
H2ac23Ratnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044
H2ac23Ratnucleus located_inIEAUniProtKB-KW:KW-05391600115GO_REF:0000043UniProtGO_REF:0000043

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
H2ac23RatDNA binding enablesIEAUniProtKB-KW:KW-02381600115GO_REF:0000043UniProtGO_REF:0000043
H2ac23RatDNA binding enablesIEAInterPro:IPR002119 and InterPro:IPR0071251600115GO_REF:0000002InterProGO_REF:0000002
H2ac23Ratprotein heterodimerization activity enablesIEAInterPro:IPR0090721600115GO_REF:0000002InterProGO_REF:0000002
H2ac23Ratstructural constituent of chromatin enablesIBAPANTHER:PTN000604564 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
H2ac23Ratstructural constituent of chromatin enablesIEAInterPro:IPR0021191600115GO_REF:0000002InterProGO_REF:0000002


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.


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Variants in H2ac23
3 total Variants

1 to 10 of 47 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
631497Bp98Blood pressure QTL 983.66arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)174135465160463643Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
1358295Aocep1Aortic cell protein QTL 16.17e-07thoracic aorta cellular protein amount (VT:0010598)aortic cell percentage174099000585990005Rat
1354640Scl32Serum cholesterol level QTL 325.4blood HDL cholesterol amount (VT:0000184)blood high density lipoprotein cholesterol level (CMO:0000052)171578159260781592Rat
152023626Bp403Blood pressure QTL 4033.86arterial blood pressure trait (VT:2000000)172393042179524188Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)173747984782479847Rat
9590107Sffal7Serum free fatty acids level QTL 74.810.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)172840914773409147Rat
2302377Scl61Serum cholesterol level QTL 614.36blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)172738994653481766Rat
70157Niddm32Non-insulin dependent diabetes mellitus QTL 324.34blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)172245492450909196Rat
724549Niddm56Non-insulin dependent diabetes mellitus QTL 560.03blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)173199078476990784Rat

1 to 10 of 47 rows






Ensembl Acc Id: ENSRNOT00000095023   ⟹   ENSRNOP00000080682
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1742,478,860 - 42,479,252 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000104913   ⟹   ENSRNOP00000094790
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1741,534,691 - 41,539,869 (+)Ensembl
RefSeq Acc Id: NM_001408932   ⟹   NP_001395861
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81741,960,723 - 41,961,309 (-)NCBI
mRatBN7.21741,532,685 - 41,533,271 (-)NCBI
Protein RefSeqs NP_001395861 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Acc Id: ENSRNOP00000094790   ⟸   ENSRNOT00000104913
Ensembl Acc Id: ENSRNOP00000080682   ⟸   ENSRNOT00000095023
RefSeq Acc Id: NP_001395861   ⟸   NM_001408932
- UniProtKB: Q64598 (UniProtKB/Swiss-Prot),   G3V9C0 (UniProtKB/TrEMBL),   A6KLN9 (UniProtKB/TrEMBL)

Name Modeler Protein Id AA Range Protein Structure
AF-G3V9C0-F1-model_v2 AlphaFold G3V9C0 1-130 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 29 of 29 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-9368 BioCyc
Ensembl Genes ENSRNOG00000056411 Ensembl
  ENSRNOG00000058437 Ensembl
  ENSRNOG00000059748 Ensembl
  ENSRNOG00000067434 Ensembl
  ENSRNOG00000070462 Ensembl
Gene3D-CATH Histone, subunit A UniProtKB/Swiss-Prot
InterPro Histone-fold UniProtKB/Swiss-Prot
  Histone_H2A UniProtKB/Swiss-Prot
  Histone_H2A/H2B/H3 UniProtKB/Swiss-Prot
  Histone_H2A_C UniProtKB/Swiss-Prot
  Histone_H2A_CS UniProtKB/Swiss-Prot
NCBI Gene 684773 ENTREZGENE
PANTHER HISTONE H2A UniProtKB/Swiss-Prot
Pfam Histone UniProtKB/Swiss-Prot
  Histone_H2A_C UniProtKB/Swiss-Prot
PhenoGen H2ac23 PhenoGen
PRINTS HISTONEH2A UniProtKB/Swiss-Prot
PROSITE HISTONE_H2A UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000056411 RatGTEx
  ENSRNOG00000058437 RatGTEx
  ENSRNOG00000059748 RatGTEx
  ENSRNOG00000067434 RatGTEx
  ENSRNOG00000070462 RatGTEx
SMART H2A UniProtKB/Swiss-Prot
Superfamily-SCOP Histone-fold UniProtKB/Swiss-Prot
UniProt A6KLN9 ENTREZGENE
  G3V9C0 ENTREZGENE
  H2A1F_RAT UniProtKB/Swiss-Prot, ENTREZGENE
1 to 29 of 29 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-25 H2ac23  H2A clustered histone 23  H2ac13  H2A clustered histone 13  Name and Symbol changed 629549 APPROVED
2022-08-25 H2ac13  H2A clustered histone 13  LOC684773  similar to histone 2a  Name and Symbol changed 629549 APPROVED
2006-11-19 LOC684773  similar to histone 2a      Symbol and Name status set to provisional 70820 PROVISIONAL