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Gene: Ripk1 (receptor interacting serine/threonine kinase 1) Rattus norvegicus
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Symbol: Ripk1
Name: receptor interacting serine/threonine kinase 1
Description: Exhibits death receptor binding activity. Involved in positive regulation of necroptotic process. Localizes to membrane raft and protein-containing complex. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human RIPK1 (receptor interacting serine/threonine kinase 1); PARTICIPATES IN ceramide signaling pathway; FasL mediated signaling pathway; Toll-like receptor signaling pathway; INTERACTS WITH 2,4-dinitrotoluene; 2-acetamidofluorene; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC306886; receptor (TNFRSF)-interacting serine-threonine kinase 1; receptor-interacting serine/threonine-protein kinase 1; RIP
Orthologs:
Homo sapiens (human) : RIPK1 (receptor interacting serine/threonine kinase 1)  HGNC  Alliance
Mus musculus (house mouse) : Ripk1 (receptor (TNFRSF)-interacting serine-threonine kinase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ripk1 (receptor interacting serine/threonine kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : RIPK1 (receptor interacting serine/threonine kinase 1)
Canis lupus familiaris (dog) : RIPK1 (receptor interacting serine/threonine kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ripk1 (receptor interacting serine/threonine kinase 1)
Sus scrofa (pig) : RIPK1 (receptor interacting serine/threonine kinase 1)
Chlorocebus sabaeus (African green monkey) : RIPK1 (receptor interacting serine/threonine kinase 1)
Heterocephalus glaber (naked mole-rat) : Ripk1 (receptor interacting serine/threonine kinase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01731,537,580 - 31,569,904 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1731,537,591 - 31,569,904 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01733,430,650 - 33,462,906 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41737,183,591 - 37,216,533 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11737,188,622 - 37,213,864 (-)NCBI
Celera1730,403,934 - 30,436,026 (-)NCBICelera
Cytogenetic Map17p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Ripk1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1310158
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.