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Gene: Sox4 (SRY-box transcription factor 4) Rattus norvegicus
Symbol: Sox4
Name: SRY-box transcription factor 4
RGD ID: 1309488
Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and miRNA binding activity. Involved in response to hypoxia. Predicted to localize to mitochondrion; nucleoplasm; and transcription regulator complex. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome and urinary bladder cancer. Orthologous to human SOX4 (SRY-box transcription factor 4); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC364712; SRY (sex determining region Y)-box 4; SRY box 4; SRY-box containing gene 4; transcription factor SOX-4
Homo sapiens (human) : SOX4 (SRY-box transcription factor 4)  HGNC  Alliance
Mus musculus (house mouse) : Sox4 (SRY (sex determining region Y)-box 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sox4 (SRY-box transcription factor 4)
Pan paniscus (bonobo/pygmy chimpanzee) : SOX4 (SRY-box transcription factor 4)
Canis lupus familiaris (dog) : SOX4 (SRY-box transcription factor 4)
Sus scrofa (pig) : SOX4 (SRY-box transcription factor 4)
Chlorocebus sabaeus (African green monkey) : SOX4 (SRY-box transcription factor 4)
Heterocephalus glaber (naked mole-rat) : Sox4 (SRY-box transcription factor 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01737,615,022 - 37,619,728 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01739,476,956 - 39,481,662 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41742,172,863 - 42,177,590 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11742,175,727 - 42,178,618 (+)NCBI
Celera1735,186,015 - 35,190,495 (+)NCBICelera
Cytogenetic Map17p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)



Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Sox4
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309488
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.