SOX4 (SRY-box transcription factor 4) - Rat Genome Database

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Gene: SOX4 (SRY-box transcription factor 4) Pan paniscus
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Symbol: SOX4
Name: SRY-box transcription factor 4
RGD ID: 11945563
Description: ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN ascending aorta morphogenesis (ortholog); atrial septum primum morphogenesis (ortholog); cardiac right ventricle morphogenesis (ortholog); ASSOCIATED WITH adenoid cystic carcinoma (ortholog); Asphyxia (ortholog); Cardiomegaly (ortholog); FOUND IN cytoplasm (ortholog); mitochondrion (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: SRY-box 4; transcription factor SOX-4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1621,765,921 - 21,771,728 (+)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v0621,422,846 - 21,427,779 (+)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
ascending aorta morphogenesis  (ISO)
atrial septum primum morphogenesis  (ISO)
cardiac right ventricle morphogenesis  (ISO)
cardiac ventricle formation  (ISO)
cellular response to glucose stimulus  (ISO)
DNA damage response, detection of DNA damage  (ISO)
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest  (ISO)
endocrine pancreas development  (ISO)
glial cell development  (ISO)
glial cell proliferation  (ISO)
glucose homeostasis  (ISO)
heart development  (ISO)
hematopoietic stem cell homeostasis  (ISO)
kidney morphogenesis  (ISO)
limb bud formation  (ISO)
mitral valve morphogenesis  (ISO)
negative regulation of cell death  (ISO)
negative regulation of cell population proliferation  (ISO)
negative regulation of protein ubiquitination  (ISO)
neural tube formation  (ISO)
neuroepithelial cell differentiation  (ISO)
noradrenergic neuron differentiation  (ISO)
positive regulation of apoptotic process  (ISO)
positive regulation of canonical Wnt signaling pathway  (ISO)
positive regulation of cell population proliferation  (ISO)
positive regulation of gamma-delta T cell differentiation  (ISO)
positive regulation of insulin secretion  (ISO)
positive regulation of N-terminal peptidyl-lysine acetylation  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
positive regulation of transcription, DNA-templated  (ISO)
positive regulation of translation  (ISO)
pro-B cell differentiation  (ISO)
protein stabilization  (ISO)
regulation of protein stability  (ISO)
regulation of transcription, DNA-templated  (ISO)
response to hypoxia  (ISO)
skeletal system development  (ISO)
somatic stem cell population maintenance  (ISO)
spinal cord development  (ISO)
spinal cord motor neuron differentiation  (ISO)
sympathetic nervous system development  (ISO)
T cell differentiation  (ISO)
ventricular septum morphogenesis  (ISO)

Cellular Component

References

Genomics

Comparative Map Data
SOX4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1621,765,921 - 21,771,728 (+)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v0621,422,846 - 21,427,779 (+)NCBIMhudiblu_PPA_v0panPan3
SOX4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl621,593,751 - 21,598,619 (+)EnsemblGRCh38hg38GRCh38
GRCh38621,593,751 - 21,598,619 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37621,593,982 - 21,598,850 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36621,701,951 - 21,706,829 (+)NCBINCBI36hg18NCBI36
Build 34621,701,950 - 21,706,826NCBI
Celera622,827,304 - 22,832,182 (+)NCBI
Cytogenetic Map6p22.3NCBI
HuRef621,537,779 - 21,542,257 (+)NCBIHuRef
CHM1_1621,596,072 - 21,600,948 (+)NCBICHM1_1
Sox4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391329,132,902 - 29,137,682 (-)NCBIGRCm39mm39
GRCm39 Ensembl1329,132,902 - 29,137,696 (-)Ensembl
GRCm381328,948,919 - 28,953,699 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1328,948,919 - 28,953,713 (-)EnsemblGRCm38mm10GRCm38
MGSCv371329,042,585 - 29,045,551 (-)NCBIGRCm37mm9NCBIm37
MGSCv361328,958,181 - 28,961,147 (-)NCBImm8
Celera1329,175,127 - 29,178,093 (-)NCBICelera
Cytogenetic Map13A3.1NCBI
cM Map1312.87NCBI
Sox4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21735,667,809 - 35,672,515 (+)NCBI
Rnor_6.01737,615,022 - 37,619,728 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01739,476,956 - 39,481,662 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41742,172,863 - 42,177,590 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11742,175,727 - 42,178,618 (+)NCBI
Celera1735,186,015 - 35,190,495 (+)NCBICelera
Cytogenetic Map17p12NCBI
Sox4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554835,076,664 - 5,077,059 (-)NCBIChiLan1.0ChiLan1.0
SOX4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13520,098,783 - 20,101,357 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3520,099,773 - 20,101,154 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3520,057,136 - 20,059,714 (+)NCBI
ROS_Cfam_1.03520,209,623 - 20,212,209 (+)NCBI
UMICH_Zoey_3.13520,010,721 - 20,014,021 (+)NCBI
UNSW_CanFamBas_1.03520,075,381 - 20,077,956 (+)NCBI
UU_Cfam_GSD_1.03521,494,787 - 21,497,360 (+)NCBI
SOX4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1716,886,834 - 16,895,488 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2717,852,748 - 17,857,158 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Sox4
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247565,128,848 - 5,156,174 (-)NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_034961534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide SSBP01000015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_034961534   ⟹   XP_034817425
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v0621,422,846 - 21,427,779 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034817425 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_034817425   ⟸   XM_034961534


Additional Information

Database Acc Id Source(s)
NCBI Gene SOX4 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-06-18 SOX4  SRY-box transcription factor 4  SOX4  SRY-box 4  Symbol and/or name change 5135510 APPROVED