Gene: Foxc1 (forkhead box C1) Rattus norvegicus
Analyze
Symbol:
Foxc1
Name:
forkhead box C1
Description:
Predicted to have several functions, including DNA binding activity; promoter-specific chromatin binding activity; and transcription coactivator activity. Predicted to be involved in several processes, including animal organ development; cell surface receptor signaling pathway; and positive regulation of cell differentiation. Predicted to localize to the cytosol; nuclear heterochromatin; and nucleoplasm. Human ortholog(s) of this gene implicated in Axenfeld-Rieger syndrome; Axenfeld-Rieger syndrome type 3; and glaucoma. Orthologous to human FOXC1 (forkhead box C1); INTERACTS WITH 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil; bisphenol A.
Type:
protein-coding
RefSeq Status:
VALIDATED
Also known as:
forkhead box protein C1; LOC364706; similar to forkhead box C1
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
FOXC1 (forkhead box C1) HGNC
Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):
Foxc1 (forkhead box C1) HGNC
NCBI, OMA, HomoloGene, Inparanoid, Panther, OrthoDB, Ensembl
Sus scrofa (pig):
FOXC1 (forkhead box C1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
FOXC2 (forkhead box C2) HGNC
OrthoDB
Alliance orthologs 3
Homo sapiens (human):
FOXC1 (forkhead box C1)
Alliance
DIOPT (Ensembl Compara, HGNC, InParanoid, OMA, OrthoFinder, PANTHER)
Mus musculus (house mouse):
Foxc1 (forkhead box C1)
Alliance
DIOPT (Ensembl Compara, InParanoid, OMA, OrthoFinder, PANTHER)
Danio rerio (zebrafish):
foxc1a (forkhead box C1a)
Alliance
DIOPT (Ensembl Compara, InParanoid, OMA, OrthoFinder, PANTHER)
Drosophila melanogaster (fruit fly):
croc
Alliance
DIOPT (Ensembl Compara, InParanoid, OrthoFinder, PANTHER)
Latest Assembly:
Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Rnor_6.0 17 33,947,501 - 33,951,484 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 17 33,947,506 - 33,951,484 (-) Ensembl Rnor_5.0 17 35,833,707 - 35,837,690 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 17 39,026,186 - 39,030,163 (-) NCBI RGSC3.4 rn4 RGSC3.4 Celera 17 32,190,633 - 32,194,475 (-) NCBI Celera Cytogenetic Map 17 p12 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Imported Annotations - ClinVar
aniridia ISO RGD:1353830 8554872 ClinVar Annotator: match by term: Aniridia ClinVar Anterior Segment Dysgenesis 3 ISO RGD:1353830 8554872 ClinVar Annotator: match by term: Iridogoniodysgenesis type1 ClinVar PMID:9792859 Anterior Segment Dysgenesis 3 ISO RGD:1353830 8554872 ClinVar Annotator: match by term: Anterior segment dysgenesis 3 ClinVar PMID:25741868 Anterior Segment Dysgenesis 3 ISO RGD:1353830 8554872 ClinVar Annotator: match by term: Iridogoniodysgenesis type1 ClinVar PMID:19793056 , PMID:28492532 Anterior Segment Dysgenesis 3 ISO RGD:1353830 8554872 ClinVar Annotator: match by term: Iridogoniodysgenesis type1 ClinVar PMID:11170889 Anterior Segment Dysgenesis 3 ISO RGD:1353830 8554872 ClinVar Annotator: match by term: Iridogoniodysgenesis type1 ClinVar PMID:9620769 Anterior Segment Dysgenesis 3 ISO RGD:1353830 8554872 ClinVar Annotator: match by term: Iridogoniodysgenesis type1 ClinVar PMID:19668217 , PMID:9620769 Anterior Segment Dysgenesis 3 ISO RGD:1353830 8554872 ClinVar Annotator: match by OMIM:601631 ClinVar PMID:11007653 more ... Anterior Segment Dysgenesis 6 ISO RGD:1353830 8554872 ClinVar Annotator: match by term: Irido-corneo-trabecular dysgenesis ClinVar PMID:11007653 more ... Anterior Segment Dysgenesis 6 ISO RGD:1353830 8554872 ClinVar Annotator: match by term: Irido-corneo-trabecular dysgenesis ClinVar PMID:11740218 more ... Anterior Segment Dysgenesis 6 ISO RGD:1353830 8554872 ClinVar Annotator: match by term: Irido-corneo-trabecular dysgenesis ClinVar PMID:12614756 , PMID:9620769 Axenfeld-Rieger syndrome ISO RGD:1353830 8554872 ClinVar Annotator: match by term: Axenfeld-rieger anomaly ClinVar PMID:9792859 Axenfeld-Rieger syndrome ISO RGD:1353830 8554872 ClinVar Annotator: match by term: Axenfeld anomaly ClinVar PMID:11170889 Axenfeld-Rieger syndrome ISO RGD:1353830 8554872 ClinVar Annotator: match by term: Axenfeld anomaly ClinVar PMID:19668217 , PMID:9620769 Axenfeld-Rieger syndrome ISO RGD:1353830 8554872 ClinVar Annotator: match by term: Axenfeld-Rieger syndrome type 3 ClinVar PMID:12614756 , PMID:9620769 Axenfeld-Rieger syndrome type 3 ISO RGD:1353830 8554872 ClinVar Annotator: match by term: Axenfeld-Rieger syndrome type 3 ClinVar PMID:28492532 Axenfeld-Rieger syndrome type 3 ISO RGD:1353830 8554872 ClinVar Annotator: match by term: Axenfeld-Rieger syndrome type 3 ClinVar PMID:23239455 , PMID:28492532 Axenfeld-Rieger syndrome type 3 ISO RGD:1353830 8554872 ClinVar Annotator: match by term: Axenfeld-Rieger syndrome type 3 ClinVar PMID:16936096 , PMID:28492532 Axenfeld-Rieger syndrome type 3 ISO RGD:1353830 8554872 ClinVar Annotator: match by term: Axenfeld-Rieger syndrome type 3 ClinVar PMID:17197537 more ... Axenfeld-Rieger syndrome type 3 ISO RGD:1353830 8554872 ClinVar Annotator: match by term: Axenfeld-Rieger syndrome type 3 ClinVar PMID:25786029 , PMID:28492532 Axenfeld-Rieger syndrome type 3 ISO RGD:1353830 8554872 ClinVar Annotator: match by term: Axenfeld-Rieger syndrome type 3 ClinVar PMID:25786029 more ... Axenfeld-Rieger syndrome type 3 ISO RGD:1353830 8554872 ClinVar Annotator: match by term: Axenfeld-Rieger syndrome type 3 ClinVar PMID:11740218 more ... Axenfeld-Rieger syndrome type 3 ISO RGD:1353830 8554872 ClinVar Annotator: match by term: Axenfeld-Rieger syndrome type 3 ClinVar PMID:11782474 , PMID:28492532 Axenfeld-Rieger syndrome type 3 ISO RGD:1353830 8554872 ClinVar Annotator: match by term: Axenfeld-Rieger syndrome type 3 ClinVar PMID:11740218 more ... Axenfeld-Rieger syndrome type 3 ISO RGD:1353830 8554872 ClinVar Annotator: match by term: Axenfeld-Rieger syndrome type 3 ClinVar PMID:20881294 more ... Axenfeld-Rieger syndrome type 3 ISO RGD:1353830 8554872 ClinVar Annotator: match by term: Axenfeld-Rieger syndrome type 3 ClinVar PMID:19793056 , PMID:28492532 Axenfeld-Rieger syndrome type 3 ISO RGD:1353830 8554872 ClinVar Annotator: match by term: Axenfeld-Rieger syndrome type 3 ClinVar PMID:11740218 more ... Axenfeld-Rieger syndrome type 3 ISO RGD:1353830 8554872 ClinVar Annotator: match by term: Axenfeld-Rieger syndrome type 3 ClinVar PMID:25741868 , PMID:25967385 Axenfeld-Rieger syndrome type 3 ISO RGD:1353830 8554872 ClinVar Annotator: match by term: Axenfeld-Rieger syndrome type 3 ClinVar PMID:19668217 more ... Axenfeld-Rieger syndrome type 3 ISO RGD:1353830 8554872 ClinVar Annotator: match by term: Axenfeld-Rieger syndrome type 3 ClinVar PMID:28432732 Axenfeld-Rieger syndrome type 3 ISO RGD:1353830 8554872 ClinVar Annotator: match by term: Axenfeld-Rieger syndrome type 3 ClinVar PMID:25741868 Axenfeld-Rieger syndrome type 3 ISO RGD:1353830 8554872 ClinVar Annotator: match by OMIM:602482 ClinVar Axenfeld-Rieger syndrome type 3 ISO RGD:1353830 8554872 ClinVar Annotator: match by term: Axenfeld-Rieger syndrome type 3 ClinVar PMID:10713890 , PMID:11170889 Axenfeld-Rieger syndrome type 3 ISO RGD:1353830 8554872 ClinVar Annotator: match by term: Axenfeld-Rieger syndrome type 3 ClinVar PMID:25741868 , PMID:28492532 Axenfeld-Rieger syndrome type 3 ISO RGD:1353830 8554872 ClinVar Annotator: match by term: Axenfeld-Rieger syndrome type 3 ClinVar PMID:11170889 more ... Axenfeld-Rieger syndrome type 3 ISO RGD:1353830 8554872 ClinVar Annotator: match by term: Axenfeld-Rieger syndrome type 3 ClinVar PMID:9620769 Axenfeld-Rieger syndrome type 3 ISO RGD:1353830 8554872 ClinVar Annotator: match by OMIM:602482 ClinVar PMID:12614756 , PMID:9620769 Iris Hypoplasia and Glaucoma ISO RGD:1353830 8554872 ClinVar Annotator: match by term: IRIS HYPOPLASIA WITH GLAUCOMA ClinVar PMID:11007653 more ... Iris Hypoplasia and Glaucoma ISO RGD:1353830 8554872 ClinVar Annotator: match by term: Iris hypoplasia and glaucoma ClinVar PMID:9620769
Imported Annotations - CTD
Axenfeld-Rieger syndrome type 1 ISO RGD:1353830 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:14630904 Dandy-Walker syndrome ISO RGD:1353830 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:19668217 open-angle glaucoma ISO RGD:1353830 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:26752265 Prostatic Neoplasms ISO RGD:1353830 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:17199135 Spinocerebellar Ataxias ISO RGD:1353830 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:19668217 tetralogy of Fallot ISO RGD:1353830 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:25093829 Imported Annotations - MGI
buphthalmos ISS RGD:1620902 13592920 OMIM:231300 MouseDO iridogoniodysgenesis syndrome ISS RGD:1353830 13592920 OMIM:137600 , OMIM:601631MouseDO Imported Annotations - OMIM
Anterior Segment Dysgenesis 3 ISO RGD:1353830 7240710 OMIM Axenfeld-Rieger syndrome type 3 ISO RGD:1353830 7240710 OMIM
17beta-estradiol increases expression ISO RGD:1353830 6480464 Estradiol results in increased expression of FOXC1 mRNA CTD PMID:16029874 more ... 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:1620902 6480464 Tetrachlorodibenzodioxin results in decreased expression of FOXC1 mRNA CTD PMID:18691609 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1620902 6480464 Tetrachlorodibenzodioxin results in increased expression of FOXC1 mRNA CTD PMID:24058054 2-methylcholine affects expression ISO RGD:1353830 6480464 beta-methylcholine affects the expression of FOXC1 mRNA CTD PMID:21179406 3-chloropropane-1,2-diol decreases expression EXP 6480464 alpha-Chlorohydrin results in decreased expression of FOXC1 mRNA CTD PMID:28522335 4,4'-sulfonyldiphenol increases expression ISO RGD:1620902 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of FOXC1 mRNA CTD PMID:30951980 5-aza-2'-deoxycytidine multiple interactions ISO RGD:1353830 6480464 [Decitabine co-treated with trichostatin A] results in increased expression of FOXC1 mRNA CTD PMID:17891453 5-fluorouracil affects expression ISO RGD:1353830 6480464 Fluorouracil affects the expression of FOXC1 mRNA CTD PMID:16584549 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of FOXC1 mRNA CTD PMID:24780913 all-trans-retinoic acid increases expression ISO RGD:1353830 6480464 Tretinoin results in increased expression of FOXC1 mRNA CTD PMID:17431108 more ... antirheumatic drug decreases expression ISO RGD:1353830 6480464 Antirheumatic Agents results in decreased expression of FOXC1 mRNA CTD PMID:24449571 atrazine multiple interactions ISO RGD:1353830 6480464 [Atrazine co-treated with Arsenates] results in increased expression of FOXC1 mRNA CTD PMID:18585445 benzalkonium chloride multiple interactions ISO RGD:1620902 6480464 [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of FOXC1 mRNA CTD PMID:30171875 benzo[a]pyrene increases expression ISO RGD:1353830 6480464 Benzo(a)pyrene results in increased expression of FOXC1 mRNA CTD PMID:20106945 more ... bis(2-chloroethyl) sulfide increases expression ISO RGD:1620902 6480464 Mustard Gas results in increased expression of FOXC1 mRNA CTD PMID:15674844 bisphenol A increases expression ISO RGD:1353830 6480464 bisphenol A results in increased expression of FOXC1 mRNA CTD PMID:16029874 , PMID:28711546 bisphenol A increases expression ISO RGD:1620902 6480464 bisphenol A results in increased expression of FOXC1 mRNA CTD PMID:30951980 bisphenol A affects methylation ISO RGD:1620902 6480464 bisphenol A affects the methylation of FOXC1 promoter CTD PMID:27334623 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of FOXC1 mRNA CTD PMID:25181051 bisphenol F increases expression ISO RGD:1620902 6480464 bisphenol F results in increased expression of FOXC1 mRNA CTD PMID:30951980 buta-1,3-diene decreases expression ISO RGD:1620902 6480464 1, 3-butadiene results in decreased expression of FOXC1 mRNA CTD PMID:29038090 calcitriol increases expression ISO RGD:1353830 6480464 Calcitriol results in increased expression of FOXC1 mRNA CTD PMID:21592394 calcitriol multiple interactions ISO RGD:1353830 6480464 [Testosterone co-treated with Calcitriol] results in increased expression of FOXC1 mRNA CTD PMID:21592394 carbamazepine affects expression ISO RGD:1353830 6480464 Carbamazepine affects the expression of FOXC1 mRNA CTD PMID:25979313 cisplatin affects response to substance ISO RGD:1353830 6480464 FOXC1 protein affects the susceptibility to Cisplatin CTD PMID:16217747 cisplatin increases expression ISO RGD:1353830 6480464 Cisplatin results in increased expression of FOXC1 mRNA CTD PMID:19561079 clomiphene decreases expression ISO RGD:1353830 6480464 Clomiphene results in decreased expression of FOXC1 mRNA CTD PMID:26865669 cobalt dichloride decreases expression ISO RGD:1353830 6480464 cobaltous chloride results in decreased expression of FOXC1 mRNA CTD PMID:19376846 copper(II) sulfate increases expression ISO RGD:1353830 6480464 Copper Sulfate results in increased expression of FOXC1 mRNA CTD PMID:19549813 cyclosporin A increases expression ISO RGD:1620902 6480464 Cyclosporine results in increased expression of FOXC1 mRNA CTD PMID:19770486 cyclosporin A decreases methylation ISO RGD:1353830 6480464 Cyclosporine results in decreased methylation of FOXC1 promoter CTD PMID:27989131 cyclosporin A decreases expression ISO RGD:1353830 6480464 Cyclosporine results in decreased expression of FOXC1 mRNA CTD PMID:27989131 cyclosporin A increases expression ISO RGD:1353830 6480464 Cyclosporine results in increased expression of FOXC1 mRNA CTD PMID:25562108 DDE increases activity ISO RGD:1353830 6480464 Dichlorodiphenyl Dichloroethylene results in increased activity of FOXC1 protein CTD PMID:27589886 dexamethasone increases expression ISO RGD:1620902 6480464 Dexamethasone results in increased expression of FOXC1 mRNA CTD PMID:22733784 diethylstilbestrol increases expression ISO RGD:1353830 6480464 Diethylstilbestrol results in increased expression of FOXC1 mRNA CTD PMID:26865669 dorsomorphin multiple interactions ISO RGD:1353830 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin decreases expression ISO RGD:1353830 6480464 Doxorubicin results in decreased expression of FOXC1 mRNA CTD PMID:29803840 estrone increases expression ISO RGD:1353830 6480464 Estrone results in increased expression of FOXC1 mRNA CTD PMID:26865669 fulvestrant decreases expression ISO RGD:1353830 6480464 fulvestrant results in decreased expression of FOXC1 mRNA CTD PMID:26865669 furan increases expression EXP 6480464 furan results in increased expression of FOXC1 mRNA CTD PMID:27387713 genistein increases expression ISO RGD:1353830 6480464 Genistein results in increased expression of FOXC1 mRNA CTD PMID:26865669 hexestrol increases expression ISO RGD:1353830 6480464 Hexestrol results in increased expression of FOXC1 mRNA CTD PMID:26865669 hydrogen peroxide affects expression ISO RGD:1353830 6480464 Hydrogen Peroxide affects the expression of FOXC1 mRNA CTD PMID:20044591 menadione affects expression ISO RGD:1353830 6480464 Vitamin K 3 affects the expression of FOXC1 mRNA CTD PMID:20044591 mercury dibromide increases expression ISO RGD:1353830 6480464 mercuric bromide results in increased expression of FOXC1 mRNA CTD PMID:26272509 mercury dibromide multiple interactions ISO RGD:1353830 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FOXC1 mRNA CTD PMID:27188386 mestranol increases expression ISO RGD:1353830 6480464 Mestranol results in increased expression of FOXC1 mRNA CTD PMID:26865669 methotrexate decreases expression ISO RGD:1353830 6480464 Methotrexate results in decreased expression of FOXC1 mRNA CTD PMID:24449571 methylmercury chloride increases expression ISO RGD:1353830 6480464 methylmercuric chloride results in increased expression of FOXC1 mRNA CTD PMID:28001369 N-methyl-4-phenylpyridinium increases methylation EXP 6480464 1-Methyl-4-phenylpyridinium results in increased methylation of FOXC1 gene CTD PMID:28801915 N-methyl-4-phenylpyridinium decreases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of FOXC1 mRNA CTD PMID:28801915 nickel atom decreases expression ISO RGD:1353830 6480464 Nickel results in decreased expression of FOXC1 mRNA CTD PMID:24768652 , PMID:25583101 p-chloromercuribenzoic acid increases expression ISO RGD:1353830 6480464 p-Chloromercuribenzoic Acid results in increased expression of FOXC1 mRNA CTD PMID:26272509 p-chloromercuribenzoic acid multiple interactions ISO RGD:1353830 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FOXC1 mRNA CTD PMID:27188386 panobinostat increases expression ISO RGD:1353830 6480464 panobinostat results in increased expression of FOXC1 mRNA CTD PMID:26272509 panobinostat multiple interactions ISO RGD:1353830 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FOXC1 mRNA CTD PMID:27188386 phenobarbital affects expression ISO RGD:1353830 6480464 Phenobarbital affects the expression of FOXC1 mRNA CTD PMID:19159669 pirinixic acid increases expression ISO RGD:1620902 6480464 pirinixic acid results in increased expression of FOXC1 mRNA CTD PMID:20813756 raloxifene decreases expression ISO RGD:1353830 6480464 Raloxifene Hydrochloride results in decreased expression of FOXC1 mRNA CTD PMID:26865669 SB 431542 multiple interactions ISO RGD:1353830 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 sodium arsenate decreases expression ISO RGD:1620902 6480464 sodium arsenate results in decreased expression of FOXC1 mRNA CTD PMID:30953684 tamoxifen affects expression ISO RGD:1353830 6480464 Tamoxifen affects the expression of FOXC1 mRNA CTD PMID:14699072 testosterone multiple interactions ISO RGD:1353830 6480464 [Testosterone co-treated with Calcitriol] results in increased expression of FOXC1 mRNA CTD PMID:21592394 testosterone increases expression ISO RGD:1353830 6480464 Testosterone results in increased expression of FOXC1 mRNA CTD PMID:21592394 thimerosal decreases expression ISO RGD:1353830 6480464 Thimerosal results in decreased expression of FOXC1 mRNA CTD PMID:27188386 titanium dioxide decreases expression ISO RGD:1620902 6480464 titanium dioxide results in decreased expression of FOXC1 mRNA CTD PMID:23557971 , PMID:29264374 toluene increases expression EXP 6480464 Toluene results in increased expression of FOXC1 mRNA CTD PMID:22967744 trichostatin A increases expression ISO RGD:1353830 6480464 trichostatin A results in increased expression of FOXC1 mRNA CTD PMID:24935251 , PMID:26272509 trichostatin A multiple interactions ISO RGD:1353830 6480464 [Decitabine co-treated with trichostatin A] results in increased expression of FOXC1 mRNA more ... CTD PMID:17891453 , PMID:27188386 triclosan decreases expression ISO RGD:1353830 6480464 Triclosan results in decreased expression of FOXC1 mRNA CTD PMID:30510588 urethane increases expression ISO RGD:1353830 6480464 Urethane results in increased expression of FOXC1 mRNA CTD PMID:28818685 valproic acid increases methylation ISO RGD:1353830 6480464 Valproic Acid results in increased methylation of FOXC1 gene CTD PMID:29154799 valproic acid multiple interactions ISO RGD:1353830 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FOXC1 mRNA CTD PMID:27188386 valproic acid increases expression ISO RGD:1353830 6480464 Valproic Acid results in increased expression of FOXC1 mRNA CTD PMID:23179753 more ... valproic acid increases expression ISO RGD:1620902 6480464 Valproic Acid analog results in increased expression of FOXC1 mRNA CTD PMID:21427059 vorinostat increases expression ISO RGD:1353830 6480464 vorinostat results in increased expression of FOXC1 mRNA CTD PMID:26272509 vorinostat multiple interactions ISO RGD:1353830 6480464 [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FOXC1 mRNA CTD PMID:27188386
Biological Process anatomical structure morphogenesis IBA MGI:MGI:1298228 more ... 13792537 PMID:21873635 GO_Central anatomical structure morphogenesis IBA MGI:MGI:1347476 , PANTHER:PTN000930906 13792537 PMID:21873635 GO_Central artery morphogenesis ISO RGD:1620902 1624291 MGI:MGI:1857869 (MGI:MGI:1345536 , PMID:10479458) RGD MGI:MGI:1345536 , PMID:10479458 artery morphogenesis IEA UniProtKB:Q61572 , ensembl:ENSMUSP000000521961600115 GO_REF:0000107 Ensembl GO_REF:0000107 biological_process ND 1598407 06/2014: no relevant rat data RGD blood vessel development ISO RGD:1620902 1624291 MGI:MGI:1347481 (MGI:MGI:3701373 , PMID:16678147) RGD MGI:MGI:3701373 , PMID:16678147 blood vessel remodeling ISO RGD:1620902 1624291 MGI:MGI:1347481 (MGI:MGI:2150572 more ... RGD MGI:MGI:2150572 more ... blood vessel remodeling IEA UniProtKB:Q61572 , ensembl:ENSMUSP000000521961600115 GO_REF:0000107 Ensembl GO_REF:0000107 brain development ISO RGD:1620902 1624291 MGI:MGI:1856705 more ... RGD MGI:MGI:1261705 more ... camera-type eye development ISO RGD:1620902 1624291 MGI:MGI:1856705 more ... RGD MGI:MGI:1340945 more ... camera-type eye development IEA UniProtKB:Q61572 , ensembl:ENSMUSP000000521961600115 GO_REF:0000107 Ensembl GO_REF:0000107 cardiac muscle cell proliferation ISO RGD:1620902 1624291 MGI:MGI:1347481 (MGI:MGI:3701735 , PMID:16839542) RGD MGI:MGI:3701735 , PMID:16839542 cardiac muscle cell proliferation IEA UniProtKB:Q61572 , ensembl:ENSMUSP000000521961600115 GO_REF:0000107 Ensembl GO_REF:0000107 cell differentiation IBA MGI:MGI:1347466 more ... 13792537 PMID:21873635 GO_Central cell differentiation IBA PANTHER:PTN000930906 , WB:WBGene00004013 13792537 PMID:21873635 GO_Central cell migration ISO RGD:1353830 1624291 (PMID:20406990), (PMID:22991501) RGD PMID:20406990 , PMID:22991501 cell population proliferation ISO RGD:1353830 1624291 (PMID:20406990), (PMID:22991501) RGD PMID:20406990 , PMID:22991501 cellular response to chemokine ISO RGD:1620902 1624291 (MGI:MGI:3773495, PMID:18187037) RGD MGI:MGI:3773495 , PMID:18187037 cellular response to epidermal growth factor stimulus ISO RGD:1353830 1624291 (PMID:16492674) RGD PMID:16492674 cellular response to epidermal growth factor stimulus IEA UniProtKB:Q12948 , ensembl:ENSP000004939061600115 GO_REF:0000107 Ensembl GO_REF:0000107 cerebellum development ISO RGD:1620902 1624291 (MGI:MGI:4359553, PMID:19668217) RGD MGI:MGI:4359553 , PMID:19668217 cerebellum development IEA UniProtKB:Q61572 , ensembl:ENSMUSP000000521961600115 GO_REF:0000107 Ensembl GO_REF:0000107 chemokine-mediated signaling pathway ISO RGD:1620902 1624291 (MGI:MGI:3773495, PMID:18187037) RGD MGI:MGI:3773495 , PMID:18187037 chemokine-mediated signaling pathway IEA UniProtKB:Q61572 , ensembl:ENSMUSP000000521961600115 GO_REF:0000107 Ensembl GO_REF:0000107 collagen fibril organization ISO RGD:1620902 1624291 MGI:MGI:1856705 (MGI:MGI:1355577 , PMID:10767326) RGD MGI:MGI:1355577 , PMID:10767326 collagen fibril organization IEA UniProtKB:Q61572 , ensembl:ENSMUSP000000521961600115 GO_REF:0000107 Ensembl GO_REF:0000107 embryonic heart tube development ISO RGD:1620902 1624291 MGI:MGI:1347481 (MGI:MGI:3701373 , PMID:16678147) RGD MGI:MGI:3701373 , PMID:16678147 embryonic heart tube development IEA UniProtKB:Q61572 , ensembl:ENSMUSP000000521961600115 GO_REF:0000107 Ensembl GO_REF:0000107 endochondral ossification ISO RGD:1620902 1624291 (MGI:MGI:5641778, PMID:25808752) RGD MGI:MGI:5641778 , PMID:25808752 endochondral ossification IEA UniProtKB:Q61572 , ensembl:ENSMUSP000000521961600115 GO_REF:0000107 Ensembl GO_REF:0000107 eye development ISO RGD:1353830 1624291 (PMID:9792859) RGD PMID:9792859 eye development ISO RGD:1620902 1624291 MGI:MGI:1856705 more ... RGD MGI:MGI:1261705 more ... germ cell migration ISO RGD:1620902 1624291 MGI:MGI:1857869 (MGI:MGI:3617053 , PMID:16412416) RGD MGI:MGI:3617053 , PMID:16412416 germ cell migration IEA UniProtKB:Q61572 , ensembl:ENSMUSP000000521961600115 GO_REF:0000107 Ensembl GO_REF:0000107 glomerular epithelium development ISO RGD:1620902 1624291 (MGI:MGI:5883353, PMID:28223138) RGD MGI:MGI:5883353 , PMID:28223138 glomerular epithelium development IEA UniProtKB:Q61572 , ensembl:ENSMUSP000000521961600115 GO_REF:0000107 Ensembl GO_REF:0000107 glycosaminoglycan metabolic process ISO RGD:1620902 1624291 MGI:MGI:1856705 (MGI:MGI:53846 , PMID:4269479) RGD MGI:MGI:53846 , PMID:4269479 glycosaminoglycan metabolic process IEA UniProtKB:Q61572 , ensembl:ENSMUSP000000521961600115 GO_REF:0000107 Ensembl GO_REF:0000107 heart development ISO RGD:1353830 1624291 (PMID:10474162) RGD PMID:10474162 heart development ISO RGD:1620902 1624291 MGI:MGI:1347481 more ... RGD MGI:MGI:1345536 more ... heart morphogenesis ISO RGD:1620902 1624291 MGI:MGI:1347481 (MGI:MGI:3701735 , PMID:16839542) RGD MGI:MGI:3701735 , PMID:16839542 in utero embryonic development ISO RGD:1620902 1624291 MGI:MGI:1856705 (MGI:MGI:53909 , PMID:4819561) RGD MGI:MGI:53909 , PMID:4819561 in utero embryonic development IEA UniProtKB:Q61572 , ensembl:ENSMUSP000000521961600115 GO_REF:0000107 Ensembl GO_REF:0000107 kidney development ISO RGD:1620902 1624291 MGI:MGI:1856705 (MGI:MGI:1353950 more ... RGD MGI:MGI:1353950 more ... lacrimal gland development ISO RGD:1620902 1624291 MGI:MGI:1857869 (MGI:MGI:3620414 , PMID:16470615) RGD MGI:MGI:3620414 , PMID:16470615 lacrimal gland development IEA UniProtKB:Q61572 , ensembl:ENSMUSP000000521961600115 GO_REF:0000107 Ensembl GO_REF:0000107 lymph vessel development ISO RGD:1620902 1624291 MGI:MGI:1347481 (MGI:MGI:3701373 , PMID:16678147) RGD MGI:MGI:3701373 , PMID:16678147 lymph vessel development IEA UniProtKB:Q61572 , ensembl:ENSMUSP000000521961600115 GO_REF:0000107 Ensembl GO_REF:0000107 maintenance of lens transparency ISO RGD:1620902 1624291 (MGI:MGI:5314489, PMID:22171010) RGD MGI:MGI:5314489 , PMID:22171010 maintenance of lens transparency IEA UniProtKB:Q61572 , ensembl:ENSMUSP000000521961600115 GO_REF:0000107 Ensembl GO_REF:0000107 mesenchymal cell development ISO RGD:1620902 1624291 (MGI:MGI:5569870, PMID:24590069) RGD MGI:MGI:5569870 , PMID:24590069 mesenchymal cell differentiation ISO RGD:1620902 1624291 MGI:MGI:1857869 (MGI:MGI:1261705 , PMID:9635428) RGD MGI:MGI:1261705 , PMID:9635428 negative regulation of angiogenesis ISO RGD:1620902 1624291 (MGI:MGI:5314489, PMID:22171010) RGD MGI:MGI:5314489 , PMID:22171010 negative regulation of angiogenesis IEA UniProtKB:Q61572 , ensembl:ENSMUSP000000521961600115 GO_REF:0000107 Ensembl GO_REF:0000107 negative regulation of apoptotic process involved in outflow tract morphogenesis ISO RGD:1620902 1624291 MGI:MGI:1347481 (MGI:MGI:3701735 , PMID:16839542) RGD MGI:MGI:3701735 , PMID:16839542 negative regulation of apoptotic process involved in outflow tract morphogenesis IEA UniProtKB:Q61572 , ensembl:ENSMUSP000000521961600115 GO_REF:0000107 Ensembl GO_REF:0000107 negative regulation of lymphangiogenesis ISO RGD:1620902 1624291 (MGI:MGI:5314489, PMID:22171010) RGD MGI:MGI:5314489 , PMID:22171010 negative regulation of lymphangiogenesis IEA UniProtKB:Q61572 , ensembl:ENSMUSP000000521961600115 GO_REF:0000107 Ensembl GO_REF:0000107 negative regulation of mitotic cell cycle ISO RGD:1353830 1624291 (PMID:12408963) RGD PMID:12408963 negative regulation of mitotic cell cycle IEA UniProtKB:Q12948 , ensembl:ENSP000004939061600115 GO_REF:0000107 Ensembl GO_REF:0000107 negative regulation of transcription by RNA polymerase II ISO RGD:1620902 1624291 (MGI:MGI:5883353, PMID:28223138) RGD MGI:MGI:5883353 , PMID:28223138 negative regulation of transcription by RNA polymerase II IEA UniProtKB:Q61572 , ensembl:ENSMUSP000000521961600115 GO_REF:0000107 Ensembl GO_REF:0000107 neural crest cell development ISO RGD:1620902 1624291 MGI:MGI:1347481 (MGI:MGI:3701735 , PMID:16839542) RGD MGI:MGI:3701735 , PMID:16839542 neural crest cell development IEA UniProtKB:Q61572 , ensembl:ENSMUSP000000521961600115 GO_REF:0000107 Ensembl GO_REF:0000107 Notch signaling pathway ISO RGD:1620902 1624291 MGI:MGI:1347481 (MGI:MGI:2150572 , PMID:11562355) RGD MGI:MGI:2150572 , PMID:11562355 Notch signaling pathway IEA UniProtKB:Q61572 , ensembl:ENSMUSP000000521961600115 GO_REF:0000107 Ensembl GO_REF:0000107 odontogenesis of dentin-containing tooth ISO RGD:1353830 1624291 (PMID:12614756) RGD PMID:12614756 odontogenesis of dentin-containing tooth IEA UniProtKB:Q12948 , ensembl:ENSP000004939061600115 GO_REF:0000107 Ensembl GO_REF:0000107 ossification ISO RGD:1620902 1624291 MGI:MGI:1856705 (MGI:MGI:2676506 , PMID:14512019) RGD MGI:MGI:2676506 , PMID:14512019 ovarian follicle development ISO RGD:1620902 1624291 MGI:MGI:1857869 (MGI:MGI:3617053 , PMID:16412416) RGD MGI:MGI:3617053 , PMID:16412416 ovarian follicle development IEA UniProtKB:Q61572 , ensembl:ENSMUSP000000521961600115 GO_REF:0000107 Ensembl GO_REF:0000107 paraxial mesoderm formation ISO RGD:1620902 1624291 MGI:MGI:1347481 (MGI:MGI:2150572 more ... RGD MGI:MGI:2150572 more ... paraxial mesoderm formation IEA UniProtKB:Q61572 , ensembl:ENSMUSP000000521961600115 GO_REF:0000107 Ensembl GO_REF:0000107 positive regulation of core promoter binding ISO RGD:1620902 1624291 (MGI:MGI:5641778, PMID:25808752) RGD MGI:MGI:5641778 , PMID:25808752 positive regulation of core promoter binding IEA UniProtKB:Q61572 , ensembl:ENSMUSP000000521961600115 GO_REF:0000107 Ensembl GO_REF:0000107 positive regulation of DNA binding ISO RGD:1353830 1624291 (PMID:26565916) RGD PMID:26565916 positive regulation of epithelial to mesenchymal transition ISO RGD:1353830 1624291 (PMID:22991501) RGD PMID:22991501 positive regulation of epithelial to mesenchymal transition IEA UniProtKB:Q12948 , ensembl:ENSP000004939061600115 GO_REF:0000107 Ensembl GO_REF:0000107 positive regulation of gene expression ISO RGD:1620902 1624291 (MGI:MGI:5569870, PMID:24590069) RGD MGI:MGI:5569870 , PMID:24590069 positive regulation of hematopoietic progenitor cell differentiation ISO RGD:1620902 1624291 (MGI:MGI:5569870, PMID:24590069) RGD MGI:MGI:5569870 , PMID:24590069 positive regulation of hematopoietic stem cell differentiation ISO RGD:1620902 1624291 (MGI:MGI:5569870, PMID:24590069) RGD MGI:MGI:5569870 , PMID:24590069 positive regulation of hematopoietic stem cell differentiation IEA UniProtKB:Q61572 , ensembl:ENSMUSP000000521961600115 GO_REF:0000107 Ensembl GO_REF:0000107 positive regulation of keratinocyte differentiation ISO RGD:1353830 1624291 (PMID:27907090) RGD PMID:27907090 positive regulation of keratinocyte differentiation IEA UniProtKB:Q12948 , ensembl:ENSP000004939061600115 GO_REF:0000107 Ensembl GO_REF:0000107 positive regulation of transcription by RNA polymerase II IEA UniProtKB:Q12948 , ensembl:ENSP000004939061600115 GO_REF:0000107 Ensembl GO_REF:0000107 positive regulation of transcription by RNA polymerase II IEA UniProtKB:Q61572 , ensembl:ENSMUSP000000521961600115 GO_REF:0000107 Ensembl GO_REF:0000107 positive regulation of transcription by RNA polymerase II ISO RGD:1620902 1624291 (MGI:MGI:3701373 more ... RGD MGI:MGI:3701373 more ... positive regulation of transcription by RNA polymerase II ISO RGD:1353830 1624291 (PMID:14578375), (PMID:16449236), (PMID:16492674), (PMID:17210863), (PMID:17993506), (PMID:19279310), (PMID:19793056), (PMID:25786029), (PMID:27804176), (PMID:27907090) RGD PMID:14578375 more ... positive regulation of transcription, DNA-templated ISO RGD:1353830 1624291 (PMID:11237714), (PMID:15277473) RGD PMID:11237714 , PMID:15277473 regulation of blood vessel diameter ISO RGD:1620902 1624291 MGI:MGI:1347481 (MGI:MGI:3701373 , PMID:16678147) RGD MGI:MGI:3701373 , PMID:16678147 regulation of blood vessel diameter IEA UniProtKB:Q61572 , ensembl:ENSMUSP000000521961600115 GO_REF:0000107 Ensembl GO_REF:0000107 regulation of organ growth ISO RGD:1620902 1624291 MGI:MGI:1347481 (MGI:MGI:3701735 , PMID:16839542) RGD MGI:MGI:3701735 , PMID:16839542 regulation of organ growth IEA UniProtKB:Q61572 , ensembl:ENSMUSP000000521961600115 GO_REF:0000107 Ensembl GO_REF:0000107 regulation of transcription by RNA polymerase II IBA FB:FBgn0000659 more ... 13792537 PMID:21873635 GO_Central regulation of transcription by RNA polymerase II IBA FB:FBgn0000659 more ... 13792537 PMID:21873635 GO_Central regulation of transcription, DNA-templated ISO RGD:1353830 1624291 (PMID:11782474), (PMID:14506133), (PMID:15299087), (PMID:15684392) RGD PMID:11782474 more ... skeletal system development ISO RGD:1620902 1624291 MGI:MGI:1856705 more ... RGD MGI:MGI:1261705 more ... somitogenesis ISO RGD:1620902 1624291 UniProtKB:Q61850 (MGI:MGI:2150572 , PMID:11562355) RGD MGI:MGI:2150572 , PMID:11562355 somitogenesis IEA UniProtKB:Q61572 , ensembl:ENSMUSP000000521961600115 GO_REF:0000107 Ensembl GO_REF:0000107 ureteric bud development ISO RGD:1620902 1624291 MGI:MGI:1856705 (MGI:MGI:1353950 , PMID:10704385) RGD MGI:MGI:1353950 , PMID:10704385 ureteric bud development IEA UniProtKB:Q61572 , ensembl:ENSMUSP000000521961600115 GO_REF:0000107 Ensembl GO_REF:0000107 vascular endothelial growth factor receptor signaling pathway ISO RGD:1620902 1624291 MGI:MGI:1347481 (MGI:MGI:3701373 , PMID:16678147) RGD MGI:MGI:3701373 , PMID:16678147 vascular endothelial growth factor receptor signaling pathway IEA UniProtKB:Q61572 , ensembl:ENSMUSP000000521961600115 GO_REF:0000107 Ensembl GO_REF:0000107 vascular endothelial growth factor signaling pathway ISO RGD:1620902 1624291 (MGI:MGI:5314489, PMID:22171010) RGD MGI:MGI:5314489 , PMID:22171010 vascular endothelial growth factor signaling pathway IEA UniProtKB:Q61572 , ensembl:ENSMUSP000000521961600115 GO_REF:0000107 Ensembl GO_REF:0000107 ventricular cardiac muscle tissue morphogenesis ISO RGD:1620902 1624291 MGI:MGI:1347481 (MGI:MGI:3701735 , PMID:16839542) RGD MGI:MGI:3701735 , PMID:16839542 ventricular cardiac muscle tissue morphogenesis IEA UniProtKB:Q61572 , ensembl:ENSMUSP000000521961600115 GO_REF:0000107 Ensembl GO_REF:0000107 Cellular Component cellular_component ND 1598407 06/2014: no relevant rat data RGD cytosol IEA UniProtKB:Q12948 , ensembl:ENSP000004939061600115 GO_REF:0000107 Ensembl GO_REF:0000107 cytosol ISO RGD:1353830 1624291 RGD GO_REF:0000052 cytosol IEA UniProtKB:W6CJ52 , ensembl:ENSP000004939061600115 GO_REF:0000107 Ensembl GO_REF:0000107 nuclear heterochromatin ISO RGD:1353830 1624291 (PMID:15684392) RGD PMID:15684392 nuclear heterochromatin IEA UniProtKB:Q12948 , ensembl:ENSP000004939061600115 GO_REF:0000107 Ensembl GO_REF:0000107 nucleoplasm ISO RGD:1353830 1624291 RGD GO_REF:0000052 nucleoplasm IEA UniProtKB:W6CJ52 , ensembl:ENSP000004939061600115 GO_REF:0000107 Ensembl GO_REF:0000107 nucleoplasm IEA UniProtKB:Q12948 , ensembl:ENSP000004939061600115 GO_REF:0000107 Ensembl GO_REF:0000107 nucleus ISO RGD:1353830 1624291 (PMID:11179011), (PMID:11562355), (PMID:11782474), (PMID:14506133), (PMID:14578375), (PMID:15277473), (PMID:15299087), (PMID:16449236), (PMID:17210863), (PMID:19279310), (PMID:19793056), (PMID:20406990), (PMID:25786029), (PMID:26565916), (PMID:27804176) RGD PMID:11179011 more ... nucleus IBA FB:FBgn0000659 more ... 13792537 PMID:21873635 GO_Central nucleus IBA FB:FBgn0000659 more ... 13792537 PMID:21873635 GO_Central nucleus ISO RGD:1620902 1624291 (MGI:MGI:5641778, PMID:25808752) RGD MGI:MGI:5641778 , PMID:25808752 Molecular Function DNA binding ISO RGD:1353830 1624291 (PMID:11179011), (PMID:15684392), (PMID:7957066) RGD PMID:11179011 more ... DNA binding, bending ISO RGD:1353830 1624291 (PMID:14506133), (PMID:7957066) RGD PMID:14506133 , PMID:7957066 DNA binding, bending IEA UniProtKB:Q12948 , ensembl:ENSP000004939061600115 GO_REF:0000107 Ensembl GO_REF:0000107 DNA-binding transcription factor activity ISO RGD:1620902 1624291 (MGI:MGI:3813419, PMID:18579532) RGD MGI:MGI:3813419 , PMID:18579532 DNA-binding transcription factor activity ISO RGD:1353830 1624291 (PMID:11179011), (PMID:11782474), (PMID:14506133), (PMID:14578375), (PMID:15277473), (PMID:15299087), (PMID:15684392), (PMID:16449236), (PMID:17210863), (PMID:19279310), (PMID:19793056), (PMID:25786029), (PMID:27804176) RGD PMID:11179011 more ... DNA-binding transcription factor activity, RNA polymerase II-specific ISO RGD:1620902 1624291 (MGI:MGI:3701373, PMID:16678147) RGD MGI:MGI:3701373 , PMID:16678147 DNA-binding transcription factor activity, RNA polymerase II-specific IBA FB:FBgn0000659 more ... 13792537 PMID:21873635 GO_Central DNA-binding transcription factor activity, RNA polymerase II-specific IBA FB:FBgn0000659 more ... 13792537 PMID:21873635 GO_Central molecular_function ND 1598407 06/2014: no relevant rat data RGD promoter-specific chromatin binding ISO RGD:1620902 1624291 (MGI:MGI:5641778, PMID:25808752) RGD MGI:MGI:5641778 , PMID:25808752 promoter-specific chromatin binding IEA UniProtKB:Q61572 , ensembl:ENSMUSP000000521961600115 GO_REF:0000107 Ensembl GO_REF:0000107 protein binding ISO RGD:1353830 1624291 UniProtKB:P21333 more ... RGD PMID:15684392 more ... RNA polymerase II regulatory region sequence-specific DNA binding ISO RGD:1353830 1624291 (PMID:7957066) RGD PMID:7957066 RNA polymerase II regulatory region sequence-specific DNA binding IEA UniProtKB:Q12948 , ensembl:ENSP000004939061600115 GO_REF:0000107 Ensembl GO_REF:0000107 sequence-specific DNA binding ISO RGD:1353830 1624291 (PMID:15277473), (PMID:7957066) RGD PMID:15277473 , PMID:7957066 sequence-specific DNA binding ISO RGD:1620902 1624291 (MGI:MGI:5641778, PMID:25808752) RGD MGI:MGI:5641778 , PMID:25808752 transcription coactivator activity ISO RGD:1620902 1624291 (MGI:MGI:5641778, PMID:25808752) RGD MGI:MGI:5641778 , PMID:25808752 transcription coactivator activity IEA UniProtKB:Q61572 , ensembl:ENSMUSP000000521961600115 GO_REF:0000107 Ensembl GO_REF:0000107 transcription coactivator binding ISO RGD:1620902 1624291 (MGI:MGI:5641778, PMID:25808752) RGD MGI:MGI:5641778 , PMID:25808752 transcription coactivator binding IEA UniProtKB:Q61572 , ensembl:ENSMUSP000000521961600115 GO_REF:0000107 Ensembl GO_REF:0000107 transcription factor binding ISO RGD:1620902 1624291 UniProtKB:Q0VGT2 (MGI:MGI:5641778 , PMID:25808752) RGD MGI:MGI:5641778 , PMID:25808752 transcription factor binding ISO RGD:1353830 1624291 UniProtKB:P10070 , UniProtKB:P40424-1 (PMID:15684392), (PMID:26565916) RGD PMID:15684392 , PMID:26565916 transcription regulatory region DNA binding ISO RGD:1620902 1624291 (MGI:MGI:3813419, PMID:18579532) RGD MGI:MGI:3813419 , PMID:18579532 transcription regulatory region DNA binding ISO RGD:1353830 1624291 (PMID:17210863), (PMID:19279310), (PMID:25786029), (PMID:27804176) RGD PMID:17210863 more ...
Gene-Chemical Interaction Annotations
