Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Dhtkd1 (dehydrogenase E1 and transketolase domain containing 1) Rattus norvegicus
Analyze
Symbol: Dhtkd1
Name: dehydrogenase E1 and transketolase domain containing 1
Description: Predicted to have oxoglutarate dehydrogenase (succinyl-transferring) activity. Predicted to be involved in hematopoietic progenitor cell differentiation and tricarboxylic acid cycle. Predicted to localize to the cytosol; mitochondrion; and oxoglutarate dehydrogenase complex. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2Q. Orthologous to human DHTKD1 (dehydrogenase E1 and transketolase domain containing 1); PARTICIPATES IN 2-aminoadipic 2-oxoadipic aciduria pathway; glutaric aciduria type I pathway; hyperlysinemia pathway; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: dehydrogenase E1 and transketolase domain-containing protein 1; LOC361272; MGC116097; probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial; probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial-like
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01776,306,585 - 76,358,058 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01778,007,307 - 78,014,756 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01777,943,860 - 78,003,052 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41783,461,479 - 83,463,086 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11783,407,566 - 83,477,143 (+)NCBI
Celera1771,810,969 - 71,857,821 (+)NCBICelera
Cytogenetic Map17q12.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Dhtkd1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1308092
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.