Exoc2 (exocyst complex component 2) - Rat Genome Database

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Gene: Exoc2 (exocyst complex component 2) Rattus norvegicus
Analyze
Symbol: Exoc2
Name: exocyst complex component 2
RGD ID: 619961
Description: Predicted to enable protein kinase binding activity and small GTPase binding activity. Predicted to be involved in Golgi to plasma membrane transport; regulation of entry of bacterium into host cell; and vesicle docking involved in exocytosis. Part of exocyst. Orthologous to human EXOC2 (exocyst complex component 2); PARTICIPATES IN insulin signaling pathway; INTERACTS WITH 1,2,4-trimethylbenzene; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: exocyst complex component 2-like; exocyst complex component Sec5; LOC103689971; Rsec5; Sec5l1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81733,714,949 - 33,906,901 (+)NCBIGRCr8
mRatBN7.21733,506,289 - 33,698,246 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1733,506,338 - 33,693,289 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1733,350,717 - 33,516,660 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01734,954,596 - 35,120,531 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01733,346,538 - 33,512,473 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01734,665,810 - 34,842,266 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1735,396,286 - 35,518,522 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1734,665,872 - 34,842,266 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01736,711,283 - 36,833,357 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01738,560,757 - 38,736,076 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41739,951,129 - 40,125,385 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11740,115,651 - 40,128,224 (+)NCBI
Celera1733,051,147 - 33,220,181 (+)NCBICelera
Cytogenetic Map17p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
exocyst  (IBA,IDA,IEA,ISO)
Flemming body  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. RalB and the exocyst mediate the cellular starvation response by direct activation of autophagosome assembly. Bodemann BO, etal., Cell. 2011 Jan 21;144(2):253-67. doi: 10.1016/j.cell.2010.12.018.
2. Structural basis of the interaction between RalA and Sec5, a subunit of the sec6/8 complex. Fukai S, etal., EMBO J. 2003 Jul 1;22(13):3267-78.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Subunit structure of the mammalian exocyst complex. Kee Y, etal., Proc Natl Acad Sci U S A 1997 Dec 23;94(26):14438-43.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
9. GOA pipeline RGD automated data pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Arl13b and the exocyst interact synergistically in ciliogenesis. Seixas C, etal., Mol Biol Cell. 2016 Jan 15;27(2):308-20. doi: 10.1091/mbc.E15-02-0061. Epub 2015 Nov 18.
Additional References at PubMed
PMID:8889548   PMID:11744922   PMID:12624092   PMID:18480549   PMID:19946888   PMID:20579884   PMID:24056301  


Genomics

Comparative Map Data
Exoc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81733,714,949 - 33,906,901 (+)NCBIGRCr8
mRatBN7.21733,506,289 - 33,698,246 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1733,506,338 - 33,693,289 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1733,350,717 - 33,516,660 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01734,954,596 - 35,120,531 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01733,346,538 - 33,512,473 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01734,665,810 - 34,842,266 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1735,396,286 - 35,518,522 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1734,665,872 - 34,842,266 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01736,711,283 - 36,833,357 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01738,560,757 - 38,736,076 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41739,951,129 - 40,125,385 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11740,115,651 - 40,128,224 (+)NCBI
Celera1733,051,147 - 33,220,181 (+)NCBICelera
Cytogenetic Map17p12NCBI
EXOC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386485,154 - 693,139 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6485,154 - 693,139 (-)EnsemblGRCh38hg38GRCh38
GRCh376485,154 - 693,139 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366430,138 - 638,109 (-)NCBINCBI36Build 36hg18NCBI36
Build 346430,138 - 638,109NCBI
Celera61,712,777 - 1,920,468 (-)NCBICelera
Cytogenetic Map6p25.3NCBI
HuRef6356,267 - 560,885 (-)NCBIHuRef
CHM1_16486,490 - 695,247 (-)NCBICHM1_1
T2T-CHM13v2.06343,220 - 550,045 (-)NCBIT2T-CHM13v2.0
Exoc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391330,968,421 - 31,162,082 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1330,997,902 - 31,158,076 (-)EnsemblGRCm39 Ensembl
GRCm39 Ensembl1330,968,416 - 30,979,209 (-)EnsemblGRCm39 Ensembl
GRCm381330,789,516 - 30,974,096 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1330,813,919 - 30,974,093 (-)EnsemblGRCm38mm10GRCm38
MGSCv371330,905,787 - 31,065,916 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361330,821,383 - 30,981,512 (-)NCBIMGSCv36mm8
Celera1331,027,688 - 31,187,698 (-)NCBICelera
Cytogenetic Map13A3.2NCBI
cM Map1313.3NCBI
Exoc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546512,330,483 - 12,461,281 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546512,327,423 - 12,457,171 (+)NCBIChiLan1.0ChiLan1.0
EXOC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2515,099,447 - 15,304,246 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1611,090,459 - 11,295,414 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06299,500 - 504,029 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16435,538 - 636,997 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6435,538 - 583,027 (-)Ensemblpanpan1.1panPan2
EXOC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.135859,158 - 1,084,228 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl35859,837 - 1,084,228 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha35872,080 - 1,096,582 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.035815,341 - 1,040,700 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl35815,367 - 1,040,685 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.135794,664 - 1,019,577 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.035812,292 - 1,037,209 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0352,148,965 - 2,373,864 (-)NCBIUU_Cfam_GSD_1.0
Exoc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494624,772,372 - 24,963,223 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366331,657,320 - 1,848,407 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366331,657,326 - 1,848,113 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EXOC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7195,083 - 341,442 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17195,079 - 341,470 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2748,090 - 194,222 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EXOC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11771,463,836 - 71,668,429 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1771,473,962 - 71,670,095 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666044410,819 - 613,460 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Exoc2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475623,740,233 - 23,880,876 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475623,740,248 - 23,878,386 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Exoc2
1199 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:200
Count of miRNA genes:140
Interacting mature miRNAs:159
Transcripts:ENSRNOT00000040371
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
2300002Iddm36Insulin dependent diabetes mellitus QTL 361.98blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)17999128640540197Rat
1354640Scl32Serum cholesterol level QTL 325.4blood HDL cholesterol amount (VT:0000184)blood high density lipoprotein cholesterol level (CMO:0000052)171578159260781592Rat
1300123Bp194Blood pressure QTL 1942.82arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)17211514934551001Rat
9590107Sffal7Serum free fatty acids level QTL 74.810.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)172840914773409147Rat
2302377Scl61Serum cholesterol level QTL 614.36blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)172738994653481766Rat
70157Niddm32Non-insulin dependent diabetes mellitus QTL 324.34blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)172245492450909196Rat
724549Niddm56Non-insulin dependent diabetes mellitus QTL 560.03blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)173199078476990784Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
1354628Stl13Serum triglyceride level QTL 133.8blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)172129303960781592Rat
1581512Cm55Cardiac mass QTL 552.80.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172702794956836890Rat
10054088Scort28Serum corticosterone level QTL 282.040.0102blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17452803849528038Rat
1354630Cm34Cardiac mass QTL 348.7heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)17429913069599340Rat
61394Bp8Blood pressure QTL 82.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172308056759555013Rat
1559055Bp278Blood pressure QTL 2780.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318468653184Rat
10450503Bp386Blood pressure QTL 3860.28arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)173136839162109574Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)17429913069599340Rat
2313854Bp343Blood pressure QTL 3433.9life span trait (VT:0005372)age at time of death (CMO:0001193)173199078450909196Rat
1354613Kidm14Kidney mass QTL 146.2kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)17429913035837242Rat
1331765Hrtrt15Heart rate QTL 154.094heart pumping trait (VT:2000009)heart rate (CMO:0000002)171533061355836425Rat
8552928Pigfal9Plasma insulin-like growth factor 1 level QTL 99blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)172840914773409147Rat
7394837Memor18Memory QTL 18exploratory behavior trait (VT:0010471)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)171864018263640182Rat
2303627Vencon8Ventilatory control QTL 80.001respiration trait (VT:0001943)tidal volume (CMO:0000222)17452803849528038Rat
12903980Cm120Cardiac mass QTL 1200.002heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)172365318468653184Rat
12903981Am17Aortic mass QTL 170.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)172365318468653184Rat
4889891Eae32Experimental allergic encephalomyelitis QTL 324.80.0002nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)172702794936146731Rat
4889955Bss93Bone structure and strength QTL 934.4tibia size trait (VT:0100001)tibia cortical bone volume to tibia total bone volume ratio (CMO:0001727)172702794960463643Rat
2303561Bw91Body weight QTL 912body mass (VT:0001259)body weight (CMO:0000012)17886846253868462Rat
12903982Kidm70Kidney mass QTL 700.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)172365318470974005Rat
631207Niddm41Non-insulin dependent diabetes mellitus QTL 41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)17137830672Rat
12903978Cm118Cardiac mass QTL 1180.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)172365318468653184Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)173136839173951021Rat
12903979Cm119Cardiac mass QTL 1190.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172365318468653184Rat
1354619Bp242Blood pressure QTL 2426.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172459934069599340Rat
1354596Bw32Body weight QTL 324.5body mass (VT:0001259)body weight (CMO:0000012)17429913060781592Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173199078481292925Rat
7488966Bp370Blood pressure QTL 3700.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318457246843Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17160781592Rat
1354659Scl68Serum cholesterol level QTL 683.9blood VLDL cholesterol amount (VT:0005144)blood very low density lipoprotein cholesterol level (CMO:0000648)171578159260781592Rat

Markers in Region
D17Wox26  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21733,677,487 - 33,677,708 (+)MAPPERmRatBN7.2
Rnor_6.01734,841,231 - 34,841,451NCBIRnor6.0
Rnor_5.01738,561,572 - 38,561,792UniSTSRnor5.0
RGSC_v3.41740,124,350 - 40,124,570UniSTSRGSC3.4
Celera1733,219,146 - 33,219,366UniSTS
Cytogenetic Map17p12UniSTS
RH128249  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21733,678,163 - 33,678,347 (+)MAPPERmRatBN7.2
Rnor_6.01734,841,907 - 34,842,090NCBIRnor6.0
Rnor_5.01738,560,933 - 38,561,116UniSTSRnor5.0
RGSC_v3.41740,125,026 - 40,125,209UniSTSRGSC3.4
Celera1733,219,822 - 33,220,005UniSTS
Cytogenetic Map17p12UniSTS
RH131719  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21733,534,738 - 33,534,952 (+)MAPPERmRatBN7.2
Rnor_6.01735,424,644 - 35,424,857NCBIRnor6.0
Rnor_6.01734,694,230 - 34,694,443NCBIRnor6.0
Rnor_5.01736,739,684 - 36,739,897UniSTSRnor5.0
Rnor_5.01738,707,443 - 38,707,656UniSTSRnor5.0
RGSC_v3.41739,979,549 - 39,979,762UniSTSRGSC3.4
Celera1733,079,548 - 33,079,761UniSTS
Cytogenetic Map17p12UniSTS
UniSTS:493122  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21733,534,112 - 33,534,943 (+)MAPPERmRatBN7.2
Rnor_6.01735,424,018 - 35,424,848NCBIRnor6.0
Rnor_6.01734,693,604 - 34,694,434NCBIRnor6.0
Rnor_5.01736,739,058 - 36,739,888UniSTSRnor5.0
Rnor_5.01738,707,452 - 38,708,282UniSTSRnor5.0
RGSC_v3.41739,978,923 - 39,979,753UniSTSRGSC3.4
Celera1733,078,922 - 33,079,752UniSTS
Cytogenetic Map17p12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 20 14 6 9 6 74 24 38 11
Low 23 43 35 10 35 8 11 11 3 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_134414 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006253891 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006253893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006253895 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095327 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA875297 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF032666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP475684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB582051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473977 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK482593 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO393045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO396803 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DV724419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000074800   ⟹   ENSRNOP00000064839
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1735,435,079 - 35,456,063 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000077110   ⟹   ENSRNOP00000072436
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1733,506,338 - 33,693,289 (+)Ensembl
Rnor_6.0 Ensembl1734,704,664 - 34,840,939 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000083674   ⟹   ENSRNOP00000074512
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1733,511,922 - 33,678,517 (+)Ensembl
Rnor_6.0 Ensembl1734,704,622 - 34,831,649 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000085704   ⟹   ENSRNOP00000074016
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1734,665,902 - 34,723,185 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000089613   ⟹   ENSRNOP00000071882
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1733,506,338 - 33,673,281 (+)Ensembl
Rnor_6.0 Ensembl1735,396,286 - 35,518,522 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000090706   ⟹   ENSRNOP00000072864
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1733,511,922 - 33,678,517 (+)Ensembl
Rnor_6.0 Ensembl1734,704,616 - 34,842,265 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000092101   ⟹   ENSRNOP00000071717
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1733,511,922 - 33,678,517 (+)Ensembl
Rnor_6.0 Ensembl1734,665,872 - 34,842,266 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000092638   ⟹   ENSRNOP00000075806
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1735,396,316 - 35,454,365 (+)Ensembl
RefSeq Acc Id: NM_134414   ⟹   NP_599241
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81733,714,980 - 33,887,178 (+)NCBI
mRatBN7.21733,506,322 - 33,678,523 (+)NCBI
Rnor_6.01734,665,810 - 34,842,266 (+)NCBI
Rnor_5.01738,560,757 - 38,736,076 (-)NCBI
RGSC_v3.41739,951,129 - 40,125,385 (+)RGD
Celera1733,051,147 - 33,220,181 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006253891   ⟹   XP_006253953
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81733,714,956 - 33,887,178 (+)NCBI
mRatBN7.21733,506,295 - 33,678,523 (+)NCBI
Rnor_6.01734,665,810 - 34,842,266 (+)NCBI
Rnor_5.01738,560,757 - 38,736,076 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039095320   ⟹   XP_038951248
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81733,714,956 - 33,906,298 (+)NCBI
mRatBN7.21733,506,295 - 33,696,677 (+)NCBI
RefSeq Acc Id: XM_039095321   ⟹   XP_038951249
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81733,752,458 - 33,905,332 (+)NCBI
mRatBN7.21733,543,822 - 33,696,677 (+)NCBI
RefSeq Acc Id: XM_039095323   ⟹   XP_038951251
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81733,714,949 - 33,905,332 (+)NCBI
mRatBN7.21733,506,289 - 33,696,677 (+)NCBI
RefSeq Acc Id: XM_039095324   ⟹   XP_038951252
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81733,714,956 - 33,906,901 (+)NCBI
mRatBN7.21733,506,295 - 33,698,246 (+)NCBI
RefSeq Acc Id: XM_039095325   ⟹   XP_038951253
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81733,714,956 - 33,905,332 (+)NCBI
mRatBN7.21733,506,295 - 33,696,677 (+)NCBI
RefSeq Acc Id: XM_039095327   ⟹   XP_038951255
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81733,714,955 - 33,905,332 (+)NCBI
mRatBN7.21733,506,295 - 33,696,677 (+)NCBI
RefSeq Acc Id: XM_063276039   ⟹   XP_063132109
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81733,714,956 - 33,887,178 (+)NCBI
RefSeq Acc Id: XM_063276040   ⟹   XP_063132110
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81733,714,956 - 33,854,441 (+)NCBI
RefSeq Acc Id: XM_063276041   ⟹   XP_063132111
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81733,714,956 - 33,870,513 (+)NCBI
RefSeq Acc Id: NP_599241   ⟸   NM_134414
- UniProtKB: O54921 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006253953   ⟸   XM_006253891
- Peptide Label: isoform X4
- UniProtKB: O54921 (UniProtKB/Swiss-Prot),   A0A0G2K416 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000071717   ⟸   ENSRNOT00000092101
Ensembl Acc Id: ENSRNOP00000072436   ⟸   ENSRNOT00000077110
Ensembl Acc Id: ENSRNOP00000072864   ⟸   ENSRNOT00000090706
Ensembl Acc Id: ENSRNOP00000074016   ⟸   ENSRNOT00000085704
Ensembl Acc Id: ENSRNOP00000074512   ⟸   ENSRNOT00000083674
RefSeq Acc Id: XP_038951251   ⟸   XM_039095323
- Peptide Label: isoform X1
- UniProtKB: F1LMB9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951252   ⟸   XM_039095324
- Peptide Label: isoform X2
- UniProtKB: F1LMB9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951248   ⟸   XM_039095320
- Peptide Label: isoform X1
- UniProtKB: F1LMB9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951255   ⟸   XM_039095327
- Peptide Label: isoform X5
- UniProtKB: F1LMB9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951253   ⟸   XM_039095325
- Peptide Label: isoform X3
- UniProtKB: F1LMB9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951249   ⟸   XM_039095321
- Peptide Label: isoform X1
- UniProtKB: F1LMB9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000064839   ⟸   ENSRNOT00000074800
Ensembl Acc Id: ENSRNOP00000071882   ⟸   ENSRNOT00000089613
Ensembl Acc Id: ENSRNOP00000075806   ⟸   ENSRNOT00000092638
RefSeq Acc Id: XP_063132109   ⟸   XM_063276039
- Peptide Label: isoform X6
- UniProtKB: O54921 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063132111   ⟸   XM_063276041
- Peptide Label: isoform X8
- UniProtKB: A0A0G2K1K8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132110   ⟸   XM_063276040
- Peptide Label: isoform X7
- UniProtKB: A0A0G2K1K8 (UniProtKB/TrEMBL)
Protein Domains
Exocyst complex component EXOC2/Sec5 N-terminal   IPT/TIG

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O54921-F1-model_v2 AlphaFold O54921 1-924 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619961 AgrOrtholog
BioCyc Gene G2FUF-9547 BioCyc
Ensembl Genes ENSRNOG00000045721 Ensembl
  ENSRNOG00000060266 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000077110.2 UniProtKB/TrEMBL
  ENSRNOT00000083674.2 UniProtKB/TrEMBL
  ENSRNOT00000089613.2 UniProtKB/TrEMBL
  ENSRNOT00000090706.2 UniProtKB/TrEMBL
  ENSRNOT00000092101.2 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro EXOC2/Sec5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EXOC2/Sec5_N_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_E-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IPT_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:171455 UniProtKB/Swiss-Prot
NCBI Gene 171455 ENTREZGENE
PANTHER EXOCYST COMPLEX COMPONENT 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR13043 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Sec5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TIG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Exoc2 PhenoGen
RatGTEx ENSRNOG00000045721 RatGTEx
  ENSRNOG00000060266 RatGTEx
Superfamily-SCOP SSF81296 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K166_RAT UniProtKB/TrEMBL
  A0A0G2K1K8 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2K416 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2K888_RAT UniProtKB/TrEMBL
  A6J7L2_RAT UniProtKB/TrEMBL
  EXOC2_RAT UniProtKB/Swiss-Prot
  F1LMB9 ENTREZGENE, UniProtKB/TrEMBL
  O54921 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Exoc2  exocyst complex component 2  LOC103689971  exocyst complex component 2-like  Data merged from RGD:9258978 737654 PROVISIONAL
2014-08-25 LOC103689971  exocyst complex component 2-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-03-30 Exoc2  exocyst complex component 2  Sec5l1  Rsec5 protein  Symbol and Name updated 1299863 APPROVED
2004-09-10 Sec5l1  Rsec5 protein  Rsec5    Symbol and Name updated 1299863 APPROVED
2002-08-07 Rsec5  Rsec5 protein      Symbol and Name status set to provisional 70820 PROVISIONAL