Exoc2 (exocyst complex component 2) - Rat Genome Database
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Gene: Exoc2 (exocyst complex component 2) Rattus norvegicus
Analyze
Symbol: Exoc2
Name: exocyst complex component 2
RGD ID: 619961
Description: Predicted to have Ral GTPase binding activity; protein N-terminus binding activity; and protein kinase binding activity. Predicted to be involved in several processes, including Golgi to plasma membrane transport; exocytosis; and regulation of entry of bacterium into host cell. Localizes to exocyst. Orthologous to human EXOC2 (exocyst complex component 2); PARTICIPATES IN insulin signaling pathway; INTERACTS WITH 1,2,4-trimethylbenzene; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: exocyst complex component Sec5; Rsec5; Sec5l1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21733,506,289 - 33,698,246 (+)NCBI
Rnor_6.0 Ensembl1734,665,872 - 34,842,266 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01734,665,810 - 34,842,266 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01736,711,283 - 36,833,357 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01738,560,757 - 38,736,076 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41739,951,129 - 40,125,385 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11740,115,651 - 40,128,224 (+)NCBI
Celera1733,051,147 - 33,220,181 (+)NCBICelera
Cytogenetic Map17p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
exocyst  (IBA,IDA,IEA,ISO)
Flemming body  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:8889548   PMID:11744922   PMID:12624092   PMID:18480549   PMID:19946888   PMID:20579884   PMID:24056301   PMID:26582389  


Genomics

Comparative Map Data
Exoc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21733,506,289 - 33,698,246 (+)NCBI
Rnor_6.0 Ensembl1734,665,872 - 34,842,266 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01734,665,810 - 34,842,266 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01736,711,283 - 36,833,357 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01738,560,757 - 38,736,076 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41739,951,129 - 40,125,385 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11740,115,651 - 40,128,224 (+)NCBI
Celera1733,051,147 - 33,220,181 (+)NCBICelera
Cytogenetic Map17p12NCBI
EXOC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl6485,154 - 693,139 (-)EnsemblGRCh38hg38GRCh38
GRCh386485,154 - 693,141 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh376485,154 - 693,139 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh376485,138 - 693,141 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366430,138 - 638,109 (-)NCBINCBI36hg18NCBI36
Build 346430,138 - 638,109NCBI
Celera61,712,777 - 1,920,468 (-)NCBI
Cytogenetic Map6p25.3NCBI
HuRef6356,267 - 560,885 (-)NCBIHuRef
CHM1_16486,490 - 695,247 (-)NCBICHM1_1
Exoc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391330,972,939 - 31,162,082 (-)NCBIGRCm39mm39
GRCm381330,789,516 - 30,974,096 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1330,813,919 - 30,974,093 (-)EnsemblGRCm38mm10GRCm38
MGSCv371330,905,787 - 31,065,916 (-)NCBIGRCm37mm9NCBIm37
MGSCv361330,821,383 - 30,981,512 (-)NCBImm8
Celera1331,027,688 - 31,187,698 (-)NCBICelera
Cytogenetic Map13A3.2NCBI
Exoc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546512,330,483 - 12,461,281 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546512,327,423 - 12,457,171 (+)NCBIChiLan1.0ChiLan1.0
EXOC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.16435,538 - 636,997 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6435,538 - 583,027 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v06299,500 - 504,029 (-)NCBIMhudiblu_PPA_v0panPan3
EXOC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl35859,837 - 1,084,228 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.135859,158 - 1,084,228 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Exoc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049366331,657,326 - 1,848,113 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EXOC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7195,081 - 341,454 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17195,079 - 341,470 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2748,090 - 194,222 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EXOC2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11771,463,836 - 71,668,429 (+)NCBI
ChlSab1.1 Ensembl1771,473,962 - 71,670,095 (+)Ensembl
Exoc2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475623,740,248 - 23,878,386 (+)NCBI

Position Markers
D17Wox26  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01734,841,231 - 34,841,451NCBIRnor6.0
Rnor_5.01738,561,572 - 38,561,792UniSTSRnor5.0
RGSC_v3.41740,124,350 - 40,124,570UniSTSRGSC3.4
Celera1733,219,146 - 33,219,366UniSTS
Cytogenetic Map17p12UniSTS
RH128249  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01734,841,907 - 34,842,090NCBIRnor6.0
Rnor_5.01738,560,933 - 38,561,116UniSTSRnor5.0
RGSC_v3.41740,125,026 - 40,125,209UniSTSRGSC3.4
Celera1733,219,822 - 33,220,005UniSTS
Cytogenetic Map17p12UniSTS
RH131719  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01734,694,230 - 34,694,443NCBIRnor6.0
Rnor_6.01735,424,644 - 35,424,857NCBIRnor6.0
Rnor_5.01738,707,443 - 38,707,656UniSTSRnor5.0
Rnor_5.01736,739,684 - 36,739,897UniSTSRnor5.0
RGSC_v3.41739,979,549 - 39,979,762UniSTSRGSC3.4
Celera1733,079,548 - 33,079,761UniSTS
Cytogenetic Map17p12UniSTS
UniSTS:493122  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01734,693,604 - 34,694,434NCBIRnor6.0
Rnor_6.01735,424,018 - 35,424,848NCBIRnor6.0
Rnor_5.01738,707,452 - 38,708,282UniSTSRnor5.0
Rnor_5.01736,739,058 - 36,739,888UniSTSRnor5.0
RGSC_v3.41739,978,923 - 39,979,753UniSTSRGSC3.4
Celera1733,078,922 - 33,079,752UniSTS
Cytogenetic Map17p12UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631207Niddm41Non-insulin dependent diabetes mellitus QTL 41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)17138243814Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17163676140Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17173413148Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17173413148Rat
1300123Bp194Blood pressure QTL 1942.82arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1751977036283402Rat
1354613Kidm14Kidney mass QTL 146.2kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)17333697237790462Rat
1354596Bw32Body weight QTL 324.5body mass (VT:0001259)body weight (CMO:0000012)17333697263676140Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)17333697273413148Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17333697273413148Rat
1354630Cm34Cardiac mass QTL 348.7heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)17333697273413148Rat
2303627Vencon8Ventilatory control QTL 80.001respiration trait (VT:0001943)tidal volume (CMO:0000222)17519104750191047Rat
10054088Scort28Serum corticosterone level QTL 282.040.0102blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17519104750191047Rat
2303561Bw91Body weight QTL 912body mass (VT:0001259)body weight (CMO:0000012)17982730454827304Rat
2300002Iddm36Insulin dependent diabetes mellitus QTL 361.98blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)171052970942542027Rat
1331765Hrtrt15Heart rate QTL 154.094heart pumping trait (VT:2000009)heart rate (CMO:0000002)171574375561036897Rat
1354640Scl32Serum cholesterol level QTL 325.4blood HDL cholesterol amount (VT:0000184)blood high density lipoprotein cholesterol level (CMO:0000052)171867614063676140Rat
1354659Scl68Serum cholesterol level QTL 683.9blood VLDL cholesterol amount (VT:0005144)blood very low density lipoprotein cholesterol level (CMO:0000648)171867614063676140Rat
7488966Bp370Blood pressure QTL 3700.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172149095062195822Rat
1559055Bp278Blood pressure QTL 2780.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172149095066490950Rat
12903978Cm118Cardiac mass QTL 1180.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)172149095066490950Rat
12903979Cm119Cardiac mass QTL 1190.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172149095066490950Rat
12903980Cm120Cardiac mass QTL 1200.002heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)172149095066490950Rat
12903981Am17Aortic mass QTL 170.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)172149095066490950Rat
12903982Kidm70Kidney mass QTL 700.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)172149095074823273Rat
70157Niddm32Non-insulin dependent diabetes mellitus QTL 324.34blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)172213681453475276Rat
61394Bp8Blood pressure QTL 82.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172277506564946194Rat
1354628Stl13Serum triglyceride level QTL 133.8blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)172403061863676140Rat
4889891Eae32Experimental allergic encephalomyelitis QTL 324.80.0002nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)172769095938110914Rat
1581512Cm55Cardiac mass QTL 552.80.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172769095961794615Rat
4889955Bss93Bone structure and strength QTL 934.4tibia size trait (VT:0100001)tibia cortical bone volume to tibia total bone volume ratio (CMO:0001727)172769095963994435Rat
2302377Scl61Serum cholesterol level QTL 614.36blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)172807358956207236Rat
1354619Bp242Blood pressure QTL 2426.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172841314873413148Rat
9590107Sffal7Serum free fatty acids level QTL 74.810.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)173097522875975228Rat
8552928Pigfal9Plasma insulin-like growth factor 1 level QTL 99blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)173097522875975228Rat
10450503Bp386Blood pressure QTL 3860.28arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)173205588258468016Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)173205588277922655Rat
2313854Bp343Blood pressure QTL 3433.9life span trait (VT:0005372)age at time of death (CMO:0001193)173330362753475276Rat
724549Niddm56Non-insulin dependent diabetes mellitus QTL 560.03blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)173330362778303627Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173330362785321557Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:200
Count of miRNA genes:140
Interacting mature miRNAs:159
Transcripts:ENSRNOT00000040371
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 20 14 6 9 6 74 24 38 11
Low 23 43 35 10 35 8 11 11 3 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_134414 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006253891 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600448 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095326 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095327 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA875297 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF032666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP475684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB582051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473977 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK482593 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO393045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO396803 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DV724419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000289 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000077110   ⟹   ENSRNOP00000072436
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1734,704,664 - 34,840,939 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000083674   ⟹   ENSRNOP00000074512
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1734,704,622 - 34,831,649 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000085704   ⟹   ENSRNOP00000074016
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1734,665,902 - 34,723,185 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000090706   ⟹   ENSRNOP00000072864
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1734,704,616 - 34,842,265 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000092101   ⟹   ENSRNOP00000071717
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1734,665,872 - 34,842,266 (+)Ensembl
RefSeq Acc Id: NM_134414   ⟹   NP_599241
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21733,506,322 - 33,678,523 (+)NCBI
Rnor_6.01734,665,810 - 34,842,266 (+)NCBI
Rnor_5.01738,560,757 - 38,736,076 (-)NCBI
RGSC_v3.41739,951,129 - 40,125,385 (+)RGD
Celera1733,051,147 - 33,220,181 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006253891   ⟹   XP_006253953
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21733,506,295 - 33,678,523 (+)NCBI
Rnor_6.01734,665,810 - 34,842,266 (+)NCBI
Rnor_5.01738,560,757 - 38,736,076 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006253893   ⟹   XP_006253955
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01734,665,825 - 34,842,266 (+)NCBI
Rnor_5.01738,560,757 - 38,736,076 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006253895   ⟹   XP_006253957
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01734,665,825 - 34,842,266 (+)NCBI
Rnor_5.01738,560,757 - 38,736,076 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600446   ⟹   XP_017455935
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01734,665,810 - 34,838,227 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017600447   ⟹   XP_017455936
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01734,665,810 - 34,842,266 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017600448   ⟹   XP_017455937
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21733,506,295 - 33,651,802 (+)NCBI
Rnor_6.01734,665,810 - 34,799,994 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039095320   ⟹   XP_038951248
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21733,506,295 - 33,696,677 (+)NCBI
RefSeq Acc Id: XM_039095321   ⟹   XP_038951249
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21733,543,822 - 33,696,677 (+)NCBI
RefSeq Acc Id: XM_039095323   ⟹   XP_038951251
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21733,506,289 - 33,696,677 (+)NCBI
RefSeq Acc Id: XM_039095324   ⟹   XP_038951252
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21733,506,295 - 33,698,246 (+)NCBI
RefSeq Acc Id: XM_039095325   ⟹   XP_038951253
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21733,506,295 - 33,696,677 (+)NCBI
RefSeq Acc Id: XM_039095326   ⟹   XP_038951254
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21733,506,289 - 33,696,677 (+)NCBI
RefSeq Acc Id: XM_039095327   ⟹   XP_038951255
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21733,506,295 - 33,696,677 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_599241   ⟸   NM_134414
- UniProtKB: O54921 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006253953   ⟸   XM_006253891
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006253957   ⟸   XM_006253895
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006253955   ⟸   XM_006253893
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017455936   ⟸   XM_017600447
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_017455935   ⟸   XM_017600446
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017455937   ⟸   XM_017600448
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: ENSRNOP00000071717   ⟸   ENSRNOT00000092101
RefSeq Acc Id: ENSRNOP00000072436   ⟸   ENSRNOT00000077110
RefSeq Acc Id: ENSRNOP00000072864   ⟸   ENSRNOT00000090706
RefSeq Acc Id: ENSRNOP00000074016   ⟸   ENSRNOT00000085704
RefSeq Acc Id: ENSRNOP00000074512   ⟸   ENSRNOT00000083674
RefSeq Acc Id: XP_038951251   ⟸   XM_039095323
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038951254   ⟸   XM_039095326
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038951252   ⟸   XM_039095324
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038951248   ⟸   XM_039095320
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038951255   ⟸   XM_039095327
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038951253   ⟸   XM_039095325
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038951249   ⟸   XM_039095321
- Peptide Label: isoform X1
Protein Domains
IPT/TIG   Sec5

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619961 AgrOrtholog
Ensembl Genes ENSRNOG00000045721 UniProtKB/TrEMBL
  ENSRNOG00000060266 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000071717 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000072436 UniProtKB/TrEMBL
  ENSRNOP00000072864 UniProtKB/TrEMBL
  ENSRNOP00000074016 UniProtKB/TrEMBL
  ENSRNOP00000074512 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000075806 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000077110 UniProtKB/TrEMBL
  ENSRNOT00000083674 UniProtKB/TrEMBL
  ENSRNOT00000085704 UniProtKB/TrEMBL
  ENSRNOT00000090706 UniProtKB/TrEMBL
  ENSRNOT00000092101 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000092638 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro EXOC2/Sec5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EXOC2/Sec5_N_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_E-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IPT_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:171455 UniProtKB/Swiss-Prot
NCBI Gene 171455 ENTREZGENE
PANTHER PTHR13043 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Sec5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TIG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Exoc2 PhenoGen
Superfamily-SCOP SSF81296 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K711_RAT UniProtKB/TrEMBL
  A0A0G2K888_RAT UniProtKB/TrEMBL
  EXOC2_RAT UniProtKB/Swiss-Prot
  F1LMB9_RAT UniProtKB/TrEMBL
  O54921 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Exoc2  exocyst complex component 2  Sec5l1  Rsec5 protein  Symbol and Name updated 1299863 APPROVED
2004-09-10 Sec5l1  Rsec5 protein  Rsec5    Symbol and Name updated 1299863 APPROVED
2002-08-07 Rsec5  Rsec5 protein      Symbol and Name status set to provisional 70820 PROVISIONAL