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Gene: E2f3 (E2F transcription factor 3) Rattus norvegicus
Symbol: E2f3
Name: E2F transcription factor 3
RGD ID: 1561600
Description: Predicted to contribute to RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including positive regulation of vascular associated smooth muscle cell apoptotic process; protein import into nucleus; and regulation of transcription by RNA polymerase II. Predicted to localize to RNA polymerase II transcription regulator complex and nucleus. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human E2F3 (E2F transcription factor 3); PARTICIPATES IN cell cycle pathway, mitotic; ceramide signaling pathway; chronic myeloid leukemia pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-acetamidofluorene; bisphenol A.
Type: protein-coding
Also known as: E2F transcription factor 3-like; LOC100361421; LOC291105; RGD1561600; similar to E2f3 protein; similar to Transcription factor E2F3 (E2F-3); transcription factor E2F3
Homo sapiens (human) : E2F3 (E2F transcription factor 3)  HGNC  Alliance
Mus musculus (house mouse) : E2f3 (E2F transcription factor 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : E2f3 (E2F transcription factor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : E2F3 (E2F transcription factor 3)
Canis lupus familiaris (dog) : E2F3 (E2F transcription factor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : E2f3 (E2F transcription factor 3)
Sus scrofa (pig) : E2F3 (E2F transcription factor 3)
Chlorocebus sabaeus (African green monkey) : E2F3 (E2F transcription factor 3)
Heterocephalus glaber (naked mole-rat) : E2f3 (E2F transcription factor 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01736,334,136 - 36,408,831 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1736,334,147 - 36,408,831 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01737,641,855 - 37,716,592 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41741,079,346 - 41,145,568 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1734,130,042 - 34,203,210 (+)NCBICelera
Cytogenetic Map17p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on E2f3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1561600
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.