Nme8 (NME/NM23 family member 8) - Rat Genome Database

Name: Nme8
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Nme8 (NME/NM23 family member 8) Rattus norvegicus

Analyze

Symbol:

Nme8

Name:

NME/NM23 family member 8

RGD ID:

735069

Description:

Predicted to have microtubule binding activity. Predicted to be involved in cellular response to reactive oxygen species; cilium assembly; and flagellated sperm motility. Localizes to sperm fibrous sheath. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 6. Orthologous to human NME8 (NME/NM23 family member 8); INTERACTS WITH bisphenol A; trichloroethene; 17alpha-ethynylestradiol (ortholog).

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

spermatid-specific thioredoxin-2 protein; sptrx-2; Sptrx2; thioredoxin domain containing 3; thioredoxin domain containing 3 (spermatozoa); thioredoxin domain-containing protein 3; Txndc3

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NME8 (NME/NM23 family member 8)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, Panther, PhylomeDB
Mus musculus (house mouse):	Nme8 (NME/NM23 family member 8)	HGNC	NCBI, HomoloGene, Inparanoid, Panther, PhylomeDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Nme8 (NME/NM23 family member 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	NME8 (NME/NM23 family member 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	NME8 (NME/NM23 family member 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Nme8 (NME/NM23 family member 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NME8 (NME/NM23 family member 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	NME8 (NME/NM23 family member 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Nme8 (NME/NM23 family member 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	NME8 (NME/NM23 family member 8)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Mus musculus (house mouse):	Nme8 (NME/NM23 family member 8)	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG18130	Alliance	DIOPT (InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	CG14221	Alliance	DIOPT (InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER)

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	17	47,300,932 - 47,368,543 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	47,301,511 - 47,368,553 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	17	56,120,328 - 56,185,444 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	17	53,037,090 - 53,105,985 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	17	53,040,678 - 53,108,823 (+)	NCBI
Celera	17	51,224,029 - 51,290,939 (-)	NCBI		Celera
Cytogenetic Map	17	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

pleomorphic xanthoastrocytoma (ISO)

primary ciliary dyskinesia 6 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17alpha-ethynylestradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

amiodarone (ISO)

antirheumatic drug (ISO)

belinostat (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

cadmium dichloride (ISO)

dorsomorphin (ISO)

entinostat (ISO)

genistein (ISO)

mercury dibromide (ISO)

methylmercury chloride (ISO)

panobinostat (ISO)

phenylmercury acetate (ISO)

SB 431542 (ISO)

sodium fluoride (ISO)

tamoxifen (ISO)

Tributyltin oxide (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

valproic acid (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to reactive oxygen species (IEA,ISO)

cilium assembly (IEA,ISO)

flagellated sperm motility (IEA,ISO)

multicellular organism development (IEA)

spermatid development (NAS)

Cellular Component

axoneme (ISO)

cytoplasm (ISO)

cytosol (IEA,ISO)

nuclear speck (IEA,ISO)

nucleus (ISO)

outer dynein arm (IEA,ISO)

sperm cytoplasmic droplet (IEA,ISO)

sperm fibrous sheath (IDA)

sperm midpiece (IEA,ISO)

sperm principal piece (IEA,ISO)

Molecular Function

microtubule binding (IEA,ISO)

References

References - curated


1.	MGD data from the GO Consortium
2.	Miranda-Vizuete A, etal., J Biol Chem 2003 Nov 7;278(45):44874-85. Epub 2003 Aug 7.
3.	OMIM Disease Annotation Pipeline
4.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:17360648	PMID:22871113	PMID:23707457

Genomics

Comparative Map Data

Nme8
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	17	47,300,932 - 47,368,543 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	47,301,511 - 47,368,553 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	17	56,120,328 - 56,185,444 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	17	53,037,090 - 53,105,985 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	17	53,040,678 - 53,108,823 (+)	NCBI
Celera	17	51,224,029 - 51,290,939 (-)	NCBI		Celera
Cytogenetic Map	17	q11	NCBI

NME8
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	7	37,848,597 - 37,900,397 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	7	37,848,597 - 37,900,397 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	7	37,887,930 - 37,940,003 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	37,854,724 - 37,906,528 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	7	37,661,438 - 37,713,238	NCBI
Celera	7	37,872,948 - 37,924,718 (+)	NCBI
Cytogenetic Map	7	p14.1	NCBI
HuRef	7	37,768,407 - 37,820,357 (+)	NCBI		HuRef
CHM1_1	7	37,887,675 - 37,939,959 (+)	NCBI		CHM1_1
CRA_TCAGchr7v2	7	37,926,134 - 37,977,903 (+)	NCBI

Nme8
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	19,829,248 - 19,881,996 (-)	NCBI	GRCm39		mm39
GRCm38	13	19,645,078 - 19,697,826 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	19,645,078 - 19,697,794 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	13	19,736,947 - 19,789,629 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	13	19,652,543 - 19,705,225 (-)	NCBI			mm8
Celera	13	19,988,291 - 19,996,418 (-)	NCBI		Celera
Cytogenetic Map	13	A2	NCBI
cM Map	13	7.0	NCBI

Nme8
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955460	5,680,678 - 5,718,628 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955460	5,672,768 - 5,718,707 (-)	NCBI	ChiLan1.0	ChiLan1.0

NME8
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	7	38,708,937 - 38,757,802 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	38,708,937 - 38,757,795 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	7	38,128,610 - 38,536,611 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

NME8
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	18	12,038,450 - 12,087,626 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	18	12,038,369 - 12,088,544 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Nme8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936478	13,176,388 - 13,243,043 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NME8
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	108,357,328 - 108,393,766 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	108,358,289 - 108,393,755 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	119,105,762 - 119,136,177 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NME8
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	20,617,683 - 20,670,346 (-)	NCBI
ChlSab1.1 Ensembl	21	20,620,941 - 20,668,888 (-)	Ensembl

Nme8
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624740	23,351,832 - 23,396,905 (-)	NCBI

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354658	Spl8	Serum phospholipid level QTL 8	3.8		blood VLDL phospholipid amount (VT:0010507)	blood very low density lipoprotein phospholipid level (CMO:0001571)	17	1	63676140	Rat
1354662	Rf49	Renal function QTL 49	2.9		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	17	1	73413148	Rat
1354581	Bp247	Blood pressure QTL 247	4.5		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	17	1	73413148	Rat
1354596	Bw32	Body weight QTL 32	4.5		body mass (VT:0001259)	body weight (CMO:0000012)	17	3336972	63676140	Rat
1354638	Insul1	Insulin level QTL 1	4.8		blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	17	3336972	73413148	Rat
1354651	Lmblg2	Limb length QTL 2	6		tibia length (VT:0004357)	tibia length (CMO:0000450)	17	3336972	73413148	Rat
1354630	Cm34	Cardiac mass QTL 34	8.7		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	17	3336972	73413148	Rat
2303627	Vencon8	Ventilatory control QTL 8		0.001	respiration trait (VT:0001943)	tidal volume (CMO:0000222)	17	5191047	50191047	Rat
10054088	Scort28	Serum corticosterone level QTL 28	2.04	0.0102	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	17	5191047	50191047	Rat
2303561	Bw91	Body weight QTL 91	2		body mass (VT:0001259)	body weight (CMO:0000012)	17	9827304	54827304	Rat
1331765	Hrtrt15	Heart rate QTL 15	4.094		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	17	15743755	61036897	Rat
1354640	Scl32	Serum cholesterol level QTL 32	5.4		blood HDL cholesterol amount (VT:0000184)	blood high density lipoprotein cholesterol level (CMO:0000052)	17	18676140	63676140	Rat
1354659	Scl68	Serum cholesterol level QTL 68	3.9		blood VLDL cholesterol amount (VT:0005144)	blood very low density lipoprotein cholesterol level (CMO:0000648)	17	18676140	63676140	Rat
7488966	Bp370	Blood pressure QTL 370		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	17	21490950	62195822	Rat
1559055	Bp278	Blood pressure QTL 278		0.04	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	17	21490950	66490950	Rat
12903978	Cm118	Cardiac mass QTL 118		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	17	21490950	66490950	Rat
12903979	Cm119	Cardiac mass QTL 119		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	17	21490950	66490950	Rat
12903980	Cm120	Cardiac mass QTL 120		0.002	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	17	21490950	66490950	Rat
12903981	Am17	Aortic mass QTL 17		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	17	21490950	66490950	Rat
12903982	Kidm70	Kidney mass QTL 70		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	17	21490950	74823273	Rat
70157	Niddm32	Non-insulin dependent diabetes mellitus QTL 32	4.34		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	17	22136814	53475276	Rat
61394	Bp8	Blood pressure QTL 8	2.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	17	22775065	64946194	Rat
1354628	Stl13	Serum triglyceride level QTL 13	3.8		blood triglyceride amount (VT:0002644)	blood triglyceride level (CMO:0000118)	17	24030618	63676140	Rat
1581512	Cm55	Cardiac mass QTL 55	2.8	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	17	27690959	61794615	Rat
4889955	Bss93	Bone structure and strength QTL 93	4.4		tibia size trait (VT:0100001)	tibia cortical bone volume to tibia total bone volume ratio (CMO:0001727)	17	27690959	63994435	Rat
2302377	Scl61	Serum cholesterol level QTL 61	4.36		blood HDL cholesterol amount (VT:0000184)	serum high density lipoprotein cholesterol level (CMO:0000361)	17	28073589	56207236	Rat
1354619	Bp242	Blood pressure QTL 242	6.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	17	28413148	73413148	Rat
9590107	Sffal7	Serum free fatty acids level QTL 7	4.81	0.001	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	17	30975228	75975228	Rat
8552928	Pigfal9	Plasma insulin-like growth factor 1 level QTL 9	9		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	17	30975228	75975228	Rat
10450503	Bp386	Blood pressure QTL 386		0.28	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	17	32055882	58468016	Rat
2324621	Coatc5	Coat color QTL 5			coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	17	32055882	77922655	Rat
2313854	Bp343	Blood pressure QTL 343	3.9		life span trait (VT:0005372)	age at time of death (CMO:0001193)	17	33303627	53475276	Rat
724549	Niddm56	Non-insulin dependent diabetes mellitus QTL 56		0.03	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	17	33303627	78303627	Rat
1354663	Bvd5	Brain ventricular dilatation QTL 5	3.51	0.001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	17	33303627	85321557	Rat
1300148	Bp192	Blood pressure QTL 192	3.47		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	17	36283245	77922655	Rat
724528	Uae4	Urinary albumin excretion QTL 4	4.9	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	17	37790306	73413148	Rat
2317054	Aia12	Adjuvant induced arthritis QTL 12	4.24		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	17	41176057	86176057	Rat
2317060	Aia26	Adjuvant induced arthritis QTL 26	3.22		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	17	41176057	86176057	Rat
2301412	Kidm40	Kidney mass QTL 40		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	17	41731080	86731080	Rat
1598871	Memor5	Memory QTL 5	5.3		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	17	42541872	85446768	Rat
631497	Bp98	Blood pressure QTL 98	3.66		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	17	42956021	63994435	Rat
1358295	Aocep1	Aortic cell protein QTL 1	6.1	0.00000071	thoracic aorta cellular protein amount (VT:0010598)	aortic cell percentage	17	44356157	89356157	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	166
Count of miRNA genes:	62
Interacting mature miRNAs:	67
Transcripts:	ENSRNOT00000059201, ENSRNOT00000059202, ENSRNOT00000066673
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium											7
Low	1		9		17				1		4	1
Below cutoff	1	8	17	12	2	12	8	9	11	4	13	9	8

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_198792	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006254088	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017600636	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017600637	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AABR07027866	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AABR07072556	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AAHX01091805	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AAHX01091806	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AAHX01091807	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC123245	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF548544	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC097265	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000087178 ⟹ ENSRNOP00000074097

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	17	47,301,518 - 47,368,541 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000090021 ⟹ ENSRNOP00000068777

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	17	47,302,272 - 47,364,209 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000092051 ⟹ ENSRNOP00000069890

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	17	47,301,511 - 47,368,553 (+)	Ensembl

RefSeq Acc Id:

NM_198792 ⟹ NP_942087

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	17	47,301,512 - 47,368,543 (+)	NCBI
Rnor_5.0	17	56,120,328 - 56,185,444 (-)	NCBI
RGSC_v3.4	17	53,037,090 - 53,105,985 (+)	RGD
Celera	17	51,224,029 - 51,290,939 (-)	RGD

Sequence:

show sequence

GGTGATGCCAGGCATCCCTCATCCCCTCCTTTAACTGGACCTGCTGGGGAAGAAGGCACAGCAG
GAACCCTGCCACCTTTAGCCTGAGCCTGACCCAGAACTGGTCCAGCAGACAAATGGCAAGCAAA
AAACGTGAAGTCCAGCTACAGTCAGTCGTCAATAGTCAGAACTTGTGGGATGAGATGTTGCTGA
ACAAAGGCTTAACAGTGATTGATGTATACCAAGCCTGGTGTGGACCCTGCAAAGCCGTGCAAGC
TTTATTCAGAAAACTAAAAAATGAACTGAATGAAGATGAGCTTCTTCATTTTGTCGTTGCGGAA
GCTGACAGCATTGTGACTCTGCAGCCATTTAGAGATAAATGTGAGCCTGTGTTCCTCTTCAGTC
TTAATGGTAAAATTATTGCAAAGATTCAGGGTGCAAATGCACCACTTATCAATAGAAAAGTCAT
TGCATTGATAGATGAAGAGAAGAAAATTGCAGCAGGTGAAATGGCTCGTCCTCAGTATGTTGAA
ATTCCACTAGTAGACTCATTGGACGAAGAATATGGGGAAGTGCACTATGAAAGTAATGTGGAAG
TTTACAATATGGCAGTTATCAACCCTGATGCTGTACTCATGAGAAAAAATTTGGAAATTAAGGA
AAAAATAACCAAAGAAGGATTTATCATAGAAATACAGGAAAACATGCTTCTCCCCGAAGAGGTA
GCGAGGGAATTCTACAATCATATGATAGATGAGCCTGACTTTGAAGAGTTTGTATATTCTATGA
CAAACCGCCTAAGCTGTGTGCTCATTATATCTCAAGGAGAAGACACAGAGGTTATTGAGGAGGA
AGCTCTCCCTCAGTCTGATGATGAAGAAGAAGAAGAAGAAGAAGAAGTAGTAGAAGAACCTGAC
CCTTTGGAAGAGCCTCACGTTAGGTTTGCACCTATGCTGGTAAAGAAGAAACGGGACAGTTTGC
AAGAGTATATGGACCGACAACATATGTCTGATTACTGTCATGTCGAGGATGATGCGGTTAAGGT
GTCCAAGTTCATTGACATATTATTCCCTGATTTTAAAACCATGAAAAGCACGAATGTACAAAGG
ACACTAGGATTACTGTATCCAGAAGTCTGTGAGGAAGAGAAAGATAATGTGTTGGACATTATTC
AAAATGAAGGGTTCACTATATTGATGCAGAGGCAAGTCGTATTATCAGAGGAAGAGGCAAGAGC
AGTGTGCCACGTCCATGAGGATGAAGACTATTTTGATAATCTTATAGGATACATGTGCAGTAAT
AACTCTTATATCCTTGTTCTAATGAGGGAACATAGTGTGGAACGTTGGAAAGAGTTAATCGGGC
CTAAAACTGTTGAGGAGGCTTATGCATCTCATCCAGACAGTTTATGTGTACGGTTTGCTTCAGG
AAATTTTCCTGTCAACCAGTTCTATGGGAGCAGTTCAAAAGCAGCAGCTGAGACAGAAATAGAG
CATTTCTTTCCTCCTCAGAGTACGCTGGCATTGATTAAGCCTCACGTGTCACACAAAGAAAGAA
TGGAGATTCTGAAGGCCATTAGAGATGCAAGATTTGAGCTGACCCAGATGAAAGAAATGCACCT
GACTCCGGAGCATGCAAGCAAAGTTTATTTCAAAATAACAGGAAAAGATTTCTATAAAAATGTA
TTGGACGTCTTATCTTCGGGCATGTCAGTAGTCATGATTCTGACCAAGTGGAATGCTGTTGGAG
AATGGAGGCGAATGATGGGCCCAGTAGACCCAGAAGAAGCAAAACTGCTGTCTCCAAATTCCCT
CCGAGCCAGATATGGAATAGACGTTTTGAGAAATGCTGTCCATGGGGCATCTAACATGTCTGAA
GCAGCAACTGCCATTAGTAATGTGTTCACAGAGAGCAATTTTGAGAACTAGGACAAATACTAGA
TTCATAGAAACTCAATGAGATAATGAAGAAGTTTCATCACATAAAACCATGAGGCACAACTTCC
TGTAAAGAGTAAGAACAAAAATTTCTCCAAGAGAAACACACATGGAGATGAAAACTCGCATGGC
TATGCATGGTAACAATAAAAACTGTAACCCCCCAA

hide sequence

RefSeq Acc Id:

XM_006254088 ⟹ XP_006254150

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	17	47,301,473 - 47,368,543 (+)	NCBI
Rnor_5.0	17	56,120,328 - 56,185,444 (-)	NCBI

Sequence:

show sequence

GGGCTGAACGTTGGTGTCTTTGCCTTTCCTTTTCCAGGGGGTGATGCCAGGCATCCCTCATCCC
CTCCTTTAACTGGACCTGCTGGGGAAGAAGGCACAGCAGGAACCCTGCCACCTTTAGCCTGAGC
CTGACCCAGAACTGGTCCAGCAGACAAATGGCAAGCAAAAAACGTGAAGTCCAGCTACAGTCAG
TCGTCAATAGTCAGAACTTGTGGGATGAGATGTTGCTGAACAAAGGCTTAACAGTGATTGATGT
ATACCAAGCCTGGTGTGGACCCTGCAAAGCCGTGCAAGCTTTATTCAGAAAACTAAAAAATGAA
CTGAATGAAGATGAGCTTCTTCATTTTGTCGTTGCGGAAGCTGACAGCATTGTGACTCTGCAGC
CATTTAGAGATAAATGTGAGCCTGTGTTCCTCTTCAGTCTTAATGGTAAAATTATTGCAAAGAT
TCAGGGTGCAAATGCACCACTTATCAATAGAAAAGTCATTGCATTGATAGATGAAGAGAAGAAA
ATTGCAGCAGGTGAAATGGCTCGTCCTCAGTATGTTGAAATTCCACTAGTAGACTCATTGGACG
AAGAATATGGGGAAGTGCACTATGAAAGTAATGTGGAAGTTTACAATATGGCAGTTATCAACCC
TGATGCTGTACTCATGAGAAAAAATTTGGAAATTAAGGAAAAAATAACCAAAGAAGGATTTATC
ATAGAAATACAGGAAAACATGCTTCTCCCCGAAGAGGTAGCGAGGGAATTCTACAATCATATGA
TAGATGAGCCTGACTTTGAAGAGTTTGTATATTCTATGACAAACCGCCTAAGCTGTGTGCTCAT
TATATCTCAAGGAGAAGACACAGAGGTTATTGAGGAGGAAGCTCTCCCTCAGTCTGATGATGAA
GAAGAAGAAGAAGAAGAAGAAGTAGTAGAAGAACCTGACCCTTTGGAAGAGCCTCACGTTAGGT
TTGCACCTATGCTGGTAAAGAAGAAACGGGACAGTTTGCAAGAGTATATGGACCGACAACATAT
GTCTGATTACTGTCATGTCGAGGATGATGCGGTTAAGGTGTCCAAGTTCATTGACATATTATTC
CCTGATTTTAAAACCATGAAAAGCACGAATGTACAAAGGACACTAGGATTACTGTATCCAGAAG
TCTGTGAGGAAGAGAAAGATAATGTGTTGGACATTATTCAAAATGAAGGGTTCACTATATTGAT
GCAGAGGCAAGTCGTATTATCAGAGGAAGAGGCAAGAGCAGTGTGCCACGTCCATGAGGATGAA
GACTATTTTGATAATCTTATAGGATACATGTGCAGTAATAACTCTTATATCCTTGTTCTAATGA
GGGAACATAGTGTGGAACGTTGGAAAGAGTTAATCGGGCCTAAAACTGTTGAGGAGGCTTATGC
ATCTCATCCAGACAGTTTATGTGTACGGTTTGCTTCAGGAAATTTTCCTGTCAACCAGTTCTAT
GGGAGCAGTTCAAAAGCAGCAGCTGAGACAGAAATAGAGCATTTCTTTCCTCCTCAGAGTACGC
TGGCATTGATTAAGCCTCACGTGTCACACAAAGAAAGAATGGAGATTCTGAAGGCCATTAGAGA
TGCAAGATTTGAGCTGACCCAGATGAAAGAAATGCACCTGACTCCGGAGCATGCAAGCAAAGTT
TATTTCAAAATAACAGGAAAAGATTTCTATAAAAATGTATTGGACGTCTTATCTTCGGGCATGT
CAGTAGTCATGATTCTGACCAAGTGGAATGCTGTTGGAGAATGGAGGCGAATGATGGGCCCAGT
AGACCCAGAAGAAGCAAAACTGCTGTCTCCAAATTCCCTCCGAGCCAGATATGGAATAGACGTT
TTGAGAAATGCTGTCCATGGGGCATCTAACATGTCTGAAGCAGCAACTGCCATTAGTAATGTGT
TCACAGAGAGCAATTTTGAGAACTAGGACAAATACTAGAAAACTCAATGAGATAATGAAGAAGT
TTCATCACATAAAACCATGAGGCACAACTTCCTGTAAAGAGTAAGAACAAAAATTTCTCCAAGA
GAAACACACATGGAGATGAAAACTCGCATGGCTATGCATGGTAACAATAAAAACTGTAACCCCC
CAA

hide sequence

RefSeq Acc Id:

XM_017600636 ⟹ XP_017456125

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	17	47,300,932 - 47,368,543 (+)	NCBI

Sequence:

show sequence

GTGGGAATCCGAATATCATTTTGGCAGAACTTTTGTAACTCTAAACATTTAAATAGTTAAAATG
GCAGTGCTATGGGTCCAGTGCCTAGGTGGGAACGGAGGAAGGAGACCATGAGGATGAGACCATC
AGAGAACAATAGCGAAGGTGGAGAGTCAGCTCAGCAGGAAGGAAGGCCTGTTTTTGCTTCAATT
TGAGGGATTTGTACGCATATTGTAAGGCTTGGCTGATCCCCTAGGATTCAAAGCCTAGGAGAGA
GACTTCCAGCAGACAAATGGCAAGCAAAAAACGTGAAGTCCAGCTACAGTCAGTCGTCAATAGT
CAGAACTTGTGGGATGAGATGTTGCTGAACAAAGGCTTAACAGTGATTGATGTATACCAAGCCT
GGTGTGGACCCTGCAAAGCCGTGCAAGCTTTATTCAGAAAACTAAAAAATGAACTGAATGAAGA
TGAGCTTCTTCATTTTGTCGTTGCGGAAGCTGACAGCATTGTGACTCTGCAGCCATTTAGAGAT
AAATGTGAGCCTGTGTTCCTCTTCAGTCTTAATGGTAAAATTATTGCAAAGATTCAGGGTGCAA
ATGCACCACTTATCAATAGAAAAGTCATTGCATTGATAGATGAAGAGAAGAAAATTGCAGCAGG
TGAAATGGCTCGTCCTCAGTATGTTGAAATTCCACTAGTAGACTCATTGGACGAAGAATATGGG
GAAGTGCACTATGAAAGTAATGTGGAAGTTTACAATATGGCAGTTATCAACCCTGATGCTGTAC
TCATGAGAAAAAATTTGGAAATTAAGGAAAAAATAACCAAAGAAGGATTTATCATAGAAATACA
GGAAAACATGCTTCTCCCCGAAGAGGTAGCGAGGGAATTCTACAATCATATGATAGATGAGCCT
GACTTTGAAGAGTTTGTATATTCTATGACAAACCGCCTAAGCTGTGTGCTCATTATATCTCAAG
GAGAAGACACAGAGGTTATTGAGGAGGAAGCTCTCCCTCAGTCTGATGATGAAGAAGAAGAAGA
AGAAGAAGAAGTAGTAGAAGAACCTGACCCTTTGGAAGAGCCTCACGTTAGGTTTGCACCTATG
CTGGTAAAGAAGAAACGGGACAGTTTGCAAGAGTATATGGACCGACAACATATGTCTGATTACT
GTCATGTCGAGGATGATGCGGTTAAGGTGTCCAAGTTCATTGACATATTATTCCCTGATTTTAA
AACCATGAAAAGCACGAATGTACAAAGGACACTAGGATTACTGTATCCAGAAGTCTGTGAGGAA
GAGAAAGATAATGTGTTGGACATTATTCAAAATGAAGGGTTCACTATATTGATGCAGAGGCAAG
TCGTATTATCAGAGGAAGAGGCAAGAGCAGTGTGCCACGTCCATGAGGATGAAGACTATTTTGA
TAATCTTATAGGATACATGTGCAGTAATAACTCTTATATCCTTGTTCTAATGAGGGAACATAGT
GTGGAACGTTGGAAAGAGTTAATCGGGCCTAAAACTGTTGAGGAGGCTTATGCATCTCATCCAG
ACAGTTTATGTGTACGGTTTGCTTCAGGAAATTTTCCTGTCAACCAGTTCTATGGGAGCAGTTC
AAAAGCAGCAGCTGAGACAGAAATAGAGCATTTCTTTCCTCCTCAGAGTACGCTGGCATTGATT
AAGCCTCACGTGTCACACAAAGAAAGAATGGAGATTCTGAAGGCCATTAGAGATGCAAGATTTG
AGCTGACCCAGATGAAAGAAATGCACCTGACTCCGGAGCATGCAAGCAAAGTTTATTTCAAAAT
AACAGGAAAAGATTTCTATAAAAATGTATTGGACGTCTTATCTTCGGGCATGTCAGTAGTCATG
ATTCTGACCAAGTGGAATGCTGTTGGAGAATGGAGGCGAATGATGGGCCCAGTAGACCCAGAAG
AAGCAAAACTGCTGTCTCCAAATTCCCTCCGAGCCAGATATGGAATAGACGTTTTGAGAAATGC
TGTCCATGGGGCATCTAACATGTCTGAAGCAGCAACTGCCATTAGTAATGTGTTCACAGAGAGC
AATTTTGAGAACTAGGACAAATACTAGAAAACTCAATGAGATAATGAAGAAGTTTCATCACATA
AAACCATGAGGCACAACTTCCTGTAAAGAGTAAGAACAAAAATTTCTCCAAGAGAAACACACAT
GGAGATGAAAACTCGCATGGCTATGCATGGTAACAATAAAAACTGTAACCCCCCAA

hide sequence

RefSeq Acc Id:

XM_017600637 ⟹ XP_017456126

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	17	47,301,473 - 47,368,543 (+)	NCBI

Sequence:

show sequence

GGGCTGAACGTTGGTGTCTTTGCCTTTCCTTTTCCAGGGGGTGATGCCAGGCATCCCTCATCCC
CTCCTTTAACTGGACCTGCTGGGGAAGAAGGCACAGCAGGAACCCTGCCACCTTTAGCCTGAGC
CTGACCCAGAACTGGTCCAGCAGACAAATGGCAAGCAAAAAACGTGAAGTCCAGCTACAGTCAG
TCGTCAATAGTCAGAACTTGTGGGATGAGATGTTGCTGAACAAAGGCTTAACAGTGATTGATGT
ATACCAAGCCTGGTGTGGACCCTGCAAAGCCGTGCAAGCTTTATTCAGAAAACTAAAAAATGAA
CTGAATGAAGATGAGCTTCTTCATTTTGTCGTTAATGGTAAAATTATTGCAAAGATTCAGGGTG
CAAATGCACCACTTATCAATAGAAAAGTCATTGCATTGATAGATGAAGAGAAGAAAATTGCAGC
AGGTGAAATGGCTCGTCCTCAGTATGTTGAAATTCCACTAGTAGACTCATTGGACGAAGAATAT
GGGGAAGTGCACTATGAAAGTAATGTGGAAGTTTACAATATGGCAGTTATCAACCCTGATGCTG
TACTCATGAGAAAAAATTTGGAAATTAAGGAAAAAATAACCAAAGAAGGATTTATCATAGAAAT
ACAGGAAAACATGCTTCTCCCCGAAGAGGTAGCGAGGGAATTCTACAATCATATGATAGATGAG
CCTGACTTTGAAGAGTTTGTATATTCTATGACAAACCGCCTAAGCTGTGTGCTCATTATATCTC
AAGGAGAAGACACAGAGGTTATTGAGGAGGAAGCTCTCCCTCAGTCTGATGATGAAGAAGAAGA
AGAAGAAGAAGAAGTAGTAGAAGAACCTGACCCTTTGGAAGAGCCTCACGTTAGGTTTGCACCT
ATGCTGGTAAAGAAGAAACGGGACAGTTTGCAAGAGTATATGGACCGACAACATATGTCTGATT
ACTGTCATGTCGAGGATGATGCGGTTAAGGTGTCCAAGTTCATTGACATATTATTCCCTGATTT
TAAAACCATGAAAAGCACGAATGTACAAAGGACACTAGGATTACTGTATCCAGAAGTCTGTGAG
GAAGAGAAAGATAATGTGTTGGACATTATTCAAAATGAAGGGTTCACTATATTGATGCAGAGGC
AAGTCGTATTATCAGAGGAAGAGGCAAGAGCAGTGTGCCACGTCCATGAGGATGAAGACTATTT
TGATAATCTTATAGGATACATGTGCAGTAATAACTCTTATATCCTTGTTCTAATGAGGGAACAT
AGTGTGGAACGTTGGAAAGAGTTAATCGGGCCTAAAACTGTTGAGGAGGCTTATGCATCTCATC
CAGACAGTTTATGTGTACGGTTTGCTTCAGGAAATTTTCCTGTCAACCAGTTCTATGGGAGCAG
TTCAAAAGCAGCAGCTGAGACAGAAATAGAGCATTTCTTTCCTCCTCAGAGTACGCTGGCATTG
ATTAAGCCTCACGTGTCACACAAAGAAAGAATGGAGATTCTGAAGGCCATTAGAGATGCAAGAT
TTGAGCTGACCCAGATGAAAGAAATGCACCTGACTCCGGAGCATGCAAGCAAAGTTTATTTCAA
AATAACAGGAAAAGATTTCTATAAAAATGTATTGGACGTCTTATCTTCGGGCATGTCAGTAGTC
ATGATTCTGACCAAGTGGAATGCTGTTGGAGAATGGAGGCGAATGATGGGCCCAGTAGACCCAG
AAGAAGCAAAACTGCTGTCTCCAAATTCCCTCCGAGCCAGATATGGAATAGACGTTTTGAGAAA
TGCTGTCCATGGGGCATCTAACATGTCTGAAGCAGCAACTGCCATTAGTAATGTGTTCACAGAG
AGCAATTTTGAGAACTAGGACAAATACTAGAAAACTCAATGAGATAATGAAGAAGTTTCATCAC
ATAAAACCATGAGGCACAACTTCCTGTAAAGAGTAAGAACAAAAATTTCTCCAAGAGAAACACA
CATGGAGATGAAAACTCGCATGGCTATGCATGGTAACAATAAAAACTGTAACCCCCCAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_942087	(Get FASTA)	NCBI Sequence Viewer
	XP_006254150	(Get FASTA)	NCBI Sequence Viewer
	XP_017456125	(Get FASTA)	NCBI Sequence Viewer
	XP_017456126	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH97265	(Get FASTA)	NCBI Sequence Viewer
	AAQ12344	(Get FASTA)	NCBI Sequence Viewer
	Q715S9	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_942087 ⟸ NM_198792

- UniProtKB:

F7EU06 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MASKKREVQLQSVVNSQNLWDEMLLNKGLTVIDVYQAWCGPCKAVQALFRKLKNELNEDELLHF
VVAEADSIVTLQPFRDKCEPVFLFSLNGKIIAKIQGANAPLINRKVIALIDEEKKIAAGEMARP
QYVEIPLVDSLDEEYGEVHYESNVEVYNMAVINPDAVLMRKNLEIKEKITKEGFIIEIQENMLL
PEEVAREFYNHMIDEPDFEEFVYSMTNRLSCVLIISQGEDTEVIEEEALPQSDDEEEEEEEEVV
EEPDPLEEPHVRFAPMLVKKKRDSLQEYMDRQHMSDYCHVEDDAVKVSKFIDILFPDFKTMKST
NVQRTLGLLYPEVCEEEKDNVLDIIQNEGFTILMQRQVVLSEEEARAVCHVHEDEDYFDNLIGY
MCSNNSYILVLMREHSVERWKELIGPKTVEEAYASHPDSLCVRFASGNFPVNQFYGSSSKAAAE
TEIEHFFPPQSTLALIKPHVSHKERMEILKAIRDARFELTQMKEMHLTPEHASKVYFKITGKDF
YKNVLDVLSSGMSVVMILTKWNAVGEWRRMMGPVDPEEAKLLSPNSLRARYGIDVLRNAVHGAS
NMSEAATAISNVFTESNFEN

hide sequence

RefSeq Acc Id:	XP_006254150 ⟸ XM_006254088
- Peptide Label:	isoform X1
- UniProtKB:	F7EU06 (UniProtKB/TrEMBL)
- Sequence:	show sequence MASKKREVQLQSVVNSQNLWDEMLLNKGLTVIDVYQAWCGPCKAVQALFRKLKNELNEDELLHF VVAEADSIVTLQPFRDKCEPVFLFSLNGKIIAKIQGANAPLINRKVIALIDEEKKIAAGEMARP QYVEIPLVDSLDEEYGEVHYESNVEVYNMAVINPDAVLMRKNLEIKEKITKEGFIIEIQENMLL PEEVAREFYNHMIDEPDFEEFVYSMTNRLSCVLIISQGEDTEVIEEEALPQSDDEEEEEEEEVV EEPDPLEEPHVRFAPMLVKKKRDSLQEYMDRQHMSDYCHVEDDAVKVSKFIDILFPDFKTMKST NVQRTLGLLYPEVCEEEKDNVLDIIQNEGFTILMQRQVVLSEEEARAVCHVHEDEDYFDNLIGY MCSNNSYILVLMREHSVERWKELIGPKTVEEAYASHPDSLCVRFASGNFPVNQFYGSSSKAAAE TEIEHFFPPQSTLALIKPHVSHKERMEILKAIRDARFELTQMKEMHLTPEHASKVYFKITGKDF YKNVLDVLSSGMSVVMILTKWNAVGEWRRMMGPVDPEEAKLLSPNSLRARYGIDVLRNAVHGAS NMSEAATAISNVFTESNFEN hide sequence

RefSeq Acc Id:	XP_017456125 ⟸ XM_017600636
- Peptide Label:	isoform X1
- UniProtKB:	F7EU06 (UniProtKB/TrEMBL)
- Sequence:	show sequence MASKKREVQLQSVVNSQNLWDEMLLNKGLTVIDVYQAWCGPCKAVQALFRKLKNELNEDELLHF VVAEADSIVTLQPFRDKCEPVFLFSLNGKIIAKIQGANAPLINRKVIALIDEEKKIAAGEMARP QYVEIPLVDSLDEEYGEVHYESNVEVYNMAVINPDAVLMRKNLEIKEKITKEGFIIEIQENMLL PEEVAREFYNHMIDEPDFEEFVYSMTNRLSCVLIISQGEDTEVIEEEALPQSDDEEEEEEEEVV EEPDPLEEPHVRFAPMLVKKKRDSLQEYMDRQHMSDYCHVEDDAVKVSKFIDILFPDFKTMKST NVQRTLGLLYPEVCEEEKDNVLDIIQNEGFTILMQRQVVLSEEEARAVCHVHEDEDYFDNLIGY MCSNNSYILVLMREHSVERWKELIGPKTVEEAYASHPDSLCVRFASGNFPVNQFYGSSSKAAAE TEIEHFFPPQSTLALIKPHVSHKERMEILKAIRDARFELTQMKEMHLTPEHASKVYFKITGKDF YKNVLDVLSSGMSVVMILTKWNAVGEWRRMMGPVDPEEAKLLSPNSLRARYGIDVLRNAVHGAS NMSEAATAISNVFTESNFEN hide sequence

RefSeq Acc Id:

XP_017456126 ⟸ XM_017600637

- Peptide Label:

isoform X2

- Sequence:

show sequence

MASKKREVQLQSVVNSQNLWDEMLLNKGLTVIDVYQAWCGPCKAVQALFRKLKNELNEDELLHF
VVNGKIIAKIQGANAPLINRKVIALIDEEKKIAAGEMARPQYVEIPLVDSLDEEYGEVHYESNV
EVYNMAVINPDAVLMRKNLEIKEKITKEGFIIEIQENMLLPEEVAREFYNHMIDEPDFEEFVYS
MTNRLSCVLIISQGEDTEVIEEEALPQSDDEEEEEEEEVVEEPDPLEEPHVRFAPMLVKKKRDS
LQEYMDRQHMSDYCHVEDDAVKVSKFIDILFPDFKTMKSTNVQRTLGLLYPEVCEEEKDNVLDI
IQNEGFTILMQRQVVLSEEEARAVCHVHEDEDYFDNLIGYMCSNNSYILVLMREHSVERWKELI
GPKTVEEAYASHPDSLCVRFASGNFPVNQFYGSSSKAAAETEIEHFFPPQSTLALIKPHVSHKE
RMEILKAIRDARFELTQMKEMHLTPEHASKVYFKITGKDFYKNVLDVLSSGMSVVMILTKWNAV
GEWRRMMGPVDPEEAKLLSPNSLRARYGIDVLRNAVHGASNMSEAATAISNVFTESNFEN

hide sequence

RefSeq Acc Id:

ENSRNOP00000069890 ⟸ ENSRNOT00000092051

RefSeq Acc Id:

ENSRNOP00000068777 ⟸ ENSRNOT00000090021

RefSeq Acc Id:

ENSRNOP00000074097 ⟸ ENSRNOT00000087178

Protein Domains

Thioredoxin

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13700501

Promoter ID:

EPDNEW_R11023

Type:

single initiation site

Name:

Nme8_1

Description:

NME/NM23 family member 8

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	17	47,301,488 - 47,301,548	EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

Visual

CSV

TAB

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

Visual

CSV

TAB

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

Visual

CSV

TAB

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

Visual

CSV

TAB

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

Visual

CSV

TAB

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

Visual

CSV

TAB

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

Visual

CSV

TAB

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

Visual

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:735069	AgrOrtholog
Ensembl Genes	ENSRNOG00000058285	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000068777	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOP00000069890	ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOP00000074097	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000087178	UniProtKB/TrEMBL
	ENSRNOT00000090021	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOT00000092051	ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH	3.30.70.141	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	3.40.30.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	NDK-like_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	NDK-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Thioredoxin-like_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Thioredoxin_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Thioredoxin_domain	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:364729	UniProtKB/TrEMBL
NCBI Gene	364729	ENTREZGENE
Pfam	NDK	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Thioredoxin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Nme8	PhenoGen
PROSITE	THIOREDOXIN_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	THIOREDOXIN_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	NDK	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF52833	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF54919	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene	Rn.107066	ENTREZGENE
UniProt	F7EU06	ENTREZGENE, UniProtKB/TrEMBL
	Q4V8P5_RAT	UniProtKB/TrEMBL
	Q715S9	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2012-10-17	Nme8	NME/NM23 family member 8	Txndc3	thioredoxin domain containing 3 (spermatozoa)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-09-10	Txndc3	thioredoxin domain containing 3 (spermatozoa)		thioredoxin domain containing 3	Name updated	1299863	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM