Prpf4b (pre-mRNA processing factor 4B) - Rat Genome Database

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Gene: Prpf4b (pre-mRNA processing factor 4B) Rattus norvegicus
Analyze
Symbol: Prpf4b
Name: pre-mRNA processing factor 4B
RGD ID: 1307784
Description: Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in positive regulation of protein export from nucleus; regulation of intracellular signal transduction; and spliceosomal tri-snRNP complex assembly. Predicted to be located in kinetochore and nuclear speck. Predicted to be part of catalytic step 2 spliceosome. Predicted to be active in nucleus. Orthologous to human PRP4K (pre-mRNA processing factor kinase PRP4K); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC291078; PRP4 pre-mRNA processing factor 4 homolog B; PRP4 pre-mRNA processing factor 4 homolog B (yeast); PRP4 pre-mRNA-processing factor 4 homolog; Prp4k; serine/threonine-protein kinase PRP4 homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81730,190,721 - 30,230,153 (-)NCBIGRCr8
mRatBN7.21729,985,343 - 30,020,285 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1729,985,343 - 30,019,625 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1729,813,167 - 29,844,178 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01731,416,901 - 31,447,908 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01729,808,887 - 29,839,898 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01730,680,454 - 30,714,542 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1730,683,640 - 30,714,495 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01732,580,447 - 32,614,537 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41736,319,606 - 36,350,616 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11736,322,446 - 36,353,457 (-)NCBI
Celera1729,558,539 - 29,589,473 (-)NCBICelera
Cytogenetic Map17p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
acrylamide  (EXP)
aflatoxin B1  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
bisphenol A  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloroprene  (EXP)
choline  (ISO)
chrysene  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
coumarin  (ISO)
Cuprizon  (EXP)
Dibutyl phosphate  (ISO)
dicrotophos  (ISO)
diethylstilbestrol  (ISO)
diuron  (EXP)
elemental selenium  (ISO)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
gentamycin  (EXP)
glyphosate  (EXP)
indometacin  (ISO)
ivermectin  (ISO)
ketamine  (EXP)
L-methionine  (ISO)
lipopolysaccharide  (ISO)
methapyrilene  (EXP)
methyl methanesulfonate  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
ochratoxin A  (ISO)
oxaliplatin  (EXP)
paracetamol  (ISO)
pirinixic acid  (ISO)
piroxicam  (ISO)
quercetin  (ISO)
raloxifene  (ISO)
resveratrol  (EXP)
rotenone  (EXP)
selenium atom  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
succimer  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
tetraphene  (ISO)
topotecan  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
Triptolide  (EXP)
troglitazone  (ISO)
uranium atom  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vincristine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
catalytic step 2 spliceosome  (IEA,ISO)
chromosome  (ISO)
kinetochore  (IEA,ISO,ISS)
nuclear speck  (IEA,ISO,ISS)
nucleus  (IBA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9701556   PMID:11991638   PMID:12477932   PMID:16778019   PMID:22681889   PMID:25931508   PMID:31505169  


Genomics

Comparative Map Data
Prpf4b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81730,190,721 - 30,230,153 (-)NCBIGRCr8
mRatBN7.21729,985,343 - 30,020,285 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1729,985,343 - 30,019,625 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1729,813,167 - 29,844,178 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01731,416,901 - 31,447,908 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01729,808,887 - 29,839,898 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01730,680,454 - 30,714,542 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1730,683,640 - 30,714,495 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01732,580,447 - 32,614,537 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41736,319,606 - 36,350,616 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11736,322,446 - 36,353,457 (-)NCBI
Celera1729,558,539 - 29,589,473 (-)NCBICelera
Cytogenetic Map17p12NCBI
PRP4K
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3864,021,300 - 4,064,983 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl64,021,267 - 4,064,983 (+)EnsemblGRCh38hg38GRCh38
GRCh3764,021,534 - 4,065,217 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3663,966,568 - 4,010,216 (+)NCBINCBI36Build 36hg18NCBI36
Build 3463,966,594 - 4,010,215NCBI
Celera65,250,468 - 5,293,786 (+)NCBICelera
Cytogenetic Map6p25.2NCBI
HuRef63,898,364 - 3,941,580 (+)NCBIHuRef
CHM1_164,024,403 - 4,067,684 (+)NCBICHM1_1
T2T-CHM13v2.063,890,936 - 3,934,285 (+)NCBIT2T-CHM13v2.0
Prpf4b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391335,058,803 - 35,090,047 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1335,059,285 - 35,090,047 (+)EnsemblGRCm39 Ensembl
GRCm381334,874,820 - 34,906,064 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1334,875,302 - 34,906,064 (+)EnsemblGRCm38mm10GRCm38
MGSCv371334,967,363 - 34,994,747 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361334,882,961 - 34,910,497 (+)NCBIMGSCv36mm8
Celera1336,002,342 - 36,029,666 (+)NCBICelera
Cytogenetic Map13A3.3NCBI
cM Map1314.21NCBI
Prp4k
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554659,359,634 - 9,392,913 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554659,359,634 - 9,392,913 (-)NCBIChiLan1.0ChiLan1.0
PRP4K
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2518,648,631 - 18,691,933 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1614,649,258 - 14,695,425 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v063,854,844 - 3,898,185 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.164,044,456 - 4,088,226 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl64,044,610 - 4,085,148 (+)Ensemblpanpan1.1panPan2
PRP4K
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1354,274,664 - 4,311,813 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl354,271,685 - 4,307,750 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha354,284,298 - 4,321,450 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0354,336,704 - 4,373,868 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl354,336,715 - 4,370,715 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1354,211,834 - 4,248,986 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0354,233,455 - 4,270,536 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0355,567,860 - 5,605,013 (+)NCBIUU_Cfam_GSD_1.0
Prp4k
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494620,110,397 - 20,149,962 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365348,382,485 - 8,418,938 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365348,379,386 - 8,418,963 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRP4K
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl72,382,495 - 2,412,908 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.172,382,498 - 2,417,085 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.272,454,111 - 2,475,718 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PRP4K
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11768,110,544 - 68,153,939 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1768,114,973 - 68,153,844 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660443,972,241 - 4,015,978 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Prp4k
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475621,038,438 - 21,082,607 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Prpf4b
68 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:197
Count of miRNA genes:137
Interacting mature miRNAs:168
Transcripts:ENSRNOT00000022902
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
2300002Iddm36Insulin dependent diabetes mellitus QTL 361.98blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)17999128640540197Rat
1354640Scl32Serum cholesterol level QTL 325.4blood HDL cholesterol amount (VT:0000184)blood high density lipoprotein cholesterol level (CMO:0000052)171578159260781592Rat
1300123Bp194Blood pressure QTL 1942.82arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)17211514934551001Rat
9590107Sffal7Serum free fatty acids level QTL 74.810.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)172840914773409147Rat
2302377Scl61Serum cholesterol level QTL 614.36blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)172738994653481766Rat
70157Niddm32Non-insulin dependent diabetes mellitus QTL 324.34blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)172245492450909196Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
1354628Stl13Serum triglyceride level QTL 133.8blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)172129303960781592Rat
1581512Cm55Cardiac mass QTL 552.80.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172702794956836890Rat
10401807Kidm52Kidney mass QTL 52kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17131701463Rat
10054088Scort28Serum corticosterone level QTL 282.040.0102blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17452803849528038Rat
1354630Cm34Cardiac mass QTL 348.7heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)17429913069599340Rat
61394Bp8Blood pressure QTL 82.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172308056759555013Rat
1559055Bp278Blood pressure QTL 2780.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318468653184Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)17429913069599340Rat
1354613Kidm14Kidney mass QTL 146.2kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)17429913035837242Rat
1331765Hrtrt15Heart rate QTL 154.094heart pumping trait (VT:2000009)heart rate (CMO:0000002)171533061355836425Rat
8552928Pigfal9Plasma insulin-like growth factor 1 level QTL 99blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)172840914773409147Rat
7394837Memor18Memory QTL 18exploratory behavior trait (VT:0010471)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)171864018263640182Rat
2303627Vencon8Ventilatory control QTL 80.001respiration trait (VT:0001943)tidal volume (CMO:0000222)17452803849528038Rat
12903980Cm120Cardiac mass QTL 1200.002heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)172365318468653184Rat
70184BpQTLcluster14Blood pressure QTL cluster 143.38arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)17131990913Rat
12903981Am17Aortic mass QTL 170.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)172365318468653184Rat
4889891Eae32Experimental allergic encephalomyelitis QTL 324.80.0002nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)172702794936146731Rat
4889955Bss93Bone structure and strength QTL 934.4tibia size trait (VT:0100001)tibia cortical bone volume to tibia total bone volume ratio (CMO:0001727)172702794960463643Rat
2303561Bw91Body weight QTL 912body mass (VT:0001259)body weight (CMO:0000012)17886846253868462Rat
12903982Kidm70Kidney mass QTL 700.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)172365318470974005Rat
631207Niddm41Non-insulin dependent diabetes mellitus QTL 41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)17137830672Rat
12903978Cm118Cardiac mass QTL 1180.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)172365318468653184Rat
12903979Cm119Cardiac mass QTL 1190.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172365318468653184Rat
1354619Bp242Blood pressure QTL 2426.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172459934069599340Rat
1354596Bw32Body weight QTL 324.5body mass (VT:0001259)body weight (CMO:0000012)17429913060781592Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat
7488966Bp370Blood pressure QTL 3700.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318457246843Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17160781592Rat
1354659Scl68Serum cholesterol level QTL 683.9blood VLDL cholesterol amount (VT:0005144)blood very low density lipoprotein cholesterol level (CMO:0000648)171578159260781592Rat

Markers in Region
D6S1932  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21729,988,556 - 29,988,736 (+)MAPPERmRatBN7.2
Rnor_6.01730,683,668 - 30,683,847NCBIRnor6.0
Rnor_5.01732,583,661 - 32,583,840UniSTSRnor5.0
RGSC_v3.41736,319,634 - 36,319,813UniSTSRGSC3.4
Celera1729,558,567 - 29,558,746UniSTS
Cytogenetic Map17p12UniSTS
RH142938  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21730,008,720 - 30,008,945 (+)MAPPERmRatBN7.2
Rnor_6.01730,703,587 - 30,703,811NCBIRnor6.0
Rnor_5.01732,603,623 - 32,603,847UniSTSRnor5.0
RGSC_v3.41736,339,793 - 36,340,017UniSTSRGSC3.4
Celera1729,578,650 - 29,578,874UniSTS
RH 3.4 Map17373.9UniSTS
Cytogenetic Map17p12UniSTS
AU048390  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21730,013,720 - 30,013,915 (+)MAPPERmRatBN7.2
Rnor_6.01730,708,587 - 30,708,781NCBIRnor6.0
Rnor_5.01732,608,623 - 32,608,817UniSTSRnor5.0
RGSC_v3.41736,344,793 - 36,344,987UniSTSRGSC3.4
Celera1729,583,650 - 29,583,844UniSTS
Cytogenetic Map17p12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 42 57 41 19 41 8 10 74 35 39 11 8
Low 1 1 2
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001011923 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095488 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276168 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276172 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_596679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_596681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_596683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_596691 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC085927 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ766876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000022902   ⟹   ENSRNOP00000022902
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1729,985,343 - 30,012,742 (-)Ensembl
Rnor_6.0 Ensembl1730,683,640 - 30,714,410 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000081993   ⟹   ENSRNOP00000072106
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1729,985,343 - 30,019,625 (-)Ensembl
Rnor_6.0 Ensembl1730,684,849 - 30,714,495 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000120267   ⟹   ENSRNOP00000092761
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1729,985,343 - 30,012,742 (-)Ensembl
RefSeq Acc Id: NM_001011923   ⟹   NP_001011923
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81730,193,907 - 30,224,920 (-)NCBI
mRatBN7.21729,988,529 - 30,019,543 (-)NCBI
Rnor_6.01730,683,640 - 30,714,410 (-)NCBI
Rnor_5.01732,580,447 - 32,614,537 (-)NCBI
RGSC_v3.41736,319,606 - 36,350,616 (-)RGD
Celera1729,558,539 - 29,589,473 (-)RGD
Sequence:
RefSeq Acc Id: XM_039095488   ⟹   XP_038951416
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81730,190,721 - 30,230,153 (-)NCBI
mRatBN7.21729,985,343 - 30,020,276 (-)NCBI
RefSeq Acc Id: XM_039095489   ⟹   XP_038951417
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81730,203,085 - 30,225,819 (-)NCBI
mRatBN7.21729,997,709 - 30,020,285 (-)NCBI
RefSeq Acc Id: XM_063276161   ⟹   XP_063132231
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81730,190,721 - 30,225,011 (-)NCBI
RefSeq Acc Id: XM_063276162   ⟹   XP_063132232
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81730,190,721 - 30,225,011 (-)NCBI
RefSeq Acc Id: XM_063276163   ⟹   XP_063132233
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81730,190,721 - 30,225,011 (-)NCBI
RefSeq Acc Id: XM_063276164   ⟹   XP_063132234
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81730,190,721 - 30,225,011 (-)NCBI
RefSeq Acc Id: XM_063276165   ⟹   XP_063132235
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81730,190,721 - 30,225,011 (-)NCBI
RefSeq Acc Id: XM_063276166   ⟹   XP_063132236
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81730,190,721 - 30,225,011 (-)NCBI
RefSeq Acc Id: XM_063276167   ⟹   XP_063132237
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81730,190,721 - 30,225,011 (-)NCBI
RefSeq Acc Id: XM_063276168   ⟹   XP_063132238
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81730,190,721 - 30,225,011 (-)NCBI
RefSeq Acc Id: XM_063276169   ⟹   XP_063132239
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81730,190,721 - 30,225,011 (-)NCBI
RefSeq Acc Id: XM_063276170   ⟹   XP_063132240
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81730,190,721 - 30,225,011 (-)NCBI
RefSeq Acc Id: XM_063276171   ⟹   XP_063132241
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81730,190,721 - 30,225,011 (-)NCBI
RefSeq Acc Id: XM_063276172   ⟹   XP_063132242
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81730,190,721 - 30,225,011 (-)NCBI
RefSeq Acc Id: XM_063276173   ⟹   XP_063132243
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81730,190,721 - 30,225,011 (-)NCBI
RefSeq Acc Id: XM_063276174   ⟹   XP_063132244
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81730,190,721 - 30,225,011 (-)NCBI
RefSeq Acc Id: XM_063276175   ⟹   XP_063132245
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81730,190,721 - 30,225,011 (-)NCBI
RefSeq Acc Id: XM_063276176   ⟹   XP_063132246
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81730,190,721 - 30,225,011 (-)NCBI
RefSeq Acc Id: XM_063276177   ⟹   XP_063132247
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81730,190,721 - 30,225,011 (-)NCBI
RefSeq Acc Id: XM_063276178   ⟹   XP_063132248
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81730,190,721 - 30,225,011 (-)NCBI
RefSeq Acc Id: XM_063276179   ⟹   XP_063132249
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81730,190,721 - 30,225,011 (-)NCBI
RefSeq Acc Id: XM_063276180   ⟹   XP_063132250
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81730,190,721 - 30,225,011 (-)NCBI
RefSeq Acc Id: XM_063276181   ⟹   XP_063132251
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81730,190,721 - 30,225,011 (-)NCBI
RefSeq Acc Id: XM_063276182   ⟹   XP_063132252
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81730,196,997 - 30,225,139 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001011923 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951416 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951417 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132231 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132232 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132233 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132234 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132235 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132236 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132237 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132238 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132239 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132240 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132241 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132242 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132243 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132244 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132245 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132246 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132247 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132248 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132249 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132250 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132251 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132252 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH85927 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000022902.7
  ENSRNOP00000072106
  ENSRNOP00000072106.2
  ENSRNOP00000092761.1
  ENSRNOP00055019179
  ENSRNOP00060012244
  ENSRNOP00065009803
GenBank Protein Q5RKH1 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001011923   ⟸   NM_001011923
- UniProtKB: Q5RKH1 (UniProtKB/Swiss-Prot),   A6J7F3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000072106   ⟸   ENSRNOT00000081993
Ensembl Acc Id: ENSRNOP00000022902   ⟸   ENSRNOT00000022902
RefSeq Acc Id: XP_038951416   ⟸   XM_039095488
- Peptide Label: isoform X1
- UniProtKB: Q5RKH1 (UniProtKB/Swiss-Prot),   A6J7F3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951417   ⟸   XM_039095489
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000092761   ⟸   ENSRNOT00000120267
RefSeq Acc Id: XP_063132236   ⟸   XM_063276166
- Peptide Label: isoform X1
- UniProtKB: Q5RKH1 (UniProtKB/Swiss-Prot),   A6J7F3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132237   ⟸   XM_063276167
- Peptide Label: isoform X1
- UniProtKB: Q5RKH1 (UniProtKB/Swiss-Prot),   A6J7F3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132251   ⟸   XM_063276181
- Peptide Label: isoform X1
- UniProtKB: Q5RKH1 (UniProtKB/Swiss-Prot),   A6J7F3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132250   ⟸   XM_063276180
- Peptide Label: isoform X1
- UniProtKB: Q5RKH1 (UniProtKB/Swiss-Prot),   A6J7F3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132248   ⟸   XM_063276178
- Peptide Label: isoform X1
- UniProtKB: Q5RKH1 (UniProtKB/Swiss-Prot),   A6J7F3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132238   ⟸   XM_063276168
- Peptide Label: isoform X1
- UniProtKB: Q5RKH1 (UniProtKB/Swiss-Prot),   A6J7F3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132232   ⟸   XM_063276162
- Peptide Label: isoform X1
- UniProtKB: Q5RKH1 (UniProtKB/Swiss-Prot),   A6J7F3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132234   ⟸   XM_063276164
- Peptide Label: isoform X1
- UniProtKB: Q5RKH1 (UniProtKB/Swiss-Prot),   A6J7F3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132235   ⟸   XM_063276165
- Peptide Label: isoform X1
- UniProtKB: Q5RKH1 (UniProtKB/Swiss-Prot),   A6J7F3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132233   ⟸   XM_063276163
- Peptide Label: isoform X1
- UniProtKB: Q5RKH1 (UniProtKB/Swiss-Prot),   A6J7F3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132231   ⟸   XM_063276161
- Peptide Label: isoform X1
- UniProtKB: Q5RKH1 (UniProtKB/Swiss-Prot),   A6J7F3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132239   ⟸   XM_063276169
- Peptide Label: isoform X1
- UniProtKB: Q5RKH1 (UniProtKB/Swiss-Prot),   A6J7F3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132249   ⟸   XM_063276179
- Peptide Label: isoform X1
- UniProtKB: Q5RKH1 (UniProtKB/Swiss-Prot),   A6J7F3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132241   ⟸   XM_063276171
- Peptide Label: isoform X1
- UniProtKB: Q5RKH1 (UniProtKB/Swiss-Prot),   A6J7F3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132247   ⟸   XM_063276177
- Peptide Label: isoform X1
- UniProtKB: Q5RKH1 (UniProtKB/Swiss-Prot),   A6J7F3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132240   ⟸   XM_063276170
- Peptide Label: isoform X1
- UniProtKB: Q5RKH1 (UniProtKB/Swiss-Prot),   A6J7F3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132246   ⟸   XM_063276176
- Peptide Label: isoform X1
- UniProtKB: Q5RKH1 (UniProtKB/Swiss-Prot),   A6J7F3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132245   ⟸   XM_063276175
- Peptide Label: isoform X1
- UniProtKB: Q5RKH1 (UniProtKB/Swiss-Prot),   A6J7F3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132244   ⟸   XM_063276174
- Peptide Label: isoform X1
- UniProtKB: Q5RKH1 (UniProtKB/Swiss-Prot),   A6J7F3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132242   ⟸   XM_063276172
- Peptide Label: isoform X1
- UniProtKB: Q5RKH1 (UniProtKB/Swiss-Prot),   A6J7F3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132243   ⟸   XM_063276173
- Peptide Label: isoform X1
- UniProtKB: Q5RKH1 (UniProtKB/Swiss-Prot),   A6J7F3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132252   ⟸   XM_063276182
- Peptide Label: isoform X2
- UniProtKB: A6J7F3 (UniProtKB/TrEMBL)
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5RKH1-F1-model_v2 AlphaFold Q5RKH1 1-1007 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700408
Promoter ID:EPDNEW_R10931
Type:initiation region
Name:Prpf4b_1
Description:pre-mRNA processing factor 4B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01730,714,492 - 30,714,552EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307784 AgrOrtholog
BioCyc Gene G2FUF-9617 BioCyc
Ensembl Genes ENSRNOG00000016705 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055013673 UniProtKB/Swiss-Prot
  ENSRNOG00060009191 UniProtKB/Swiss-Prot
  ENSRNOG00065008310 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000022902.8 UniProtKB/TrEMBL
  ENSRNOT00000081993 UniProtKB/TrEMBL
  ENSRNOT00000081993.2 UniProtKB/Swiss-Prot
  ENSRNOT00000120267.1 UniProtKB/TrEMBL
  ENSRNOT00055023571 UniProtKB/Swiss-Prot
  ENSRNOT00060015713 UniProtKB/Swiss-Prot
  ENSRNOT00065013236 UniProtKB/Swiss-Prot
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7110150 IMAGE-MGC_LOAD
InterPro Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STKc_PRP4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:291078 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94868 IMAGE-MGC_LOAD
NCBI Gene 291078 ENTREZGENE
PANTHER DUAL SPECIFICITY PROTEIN KINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MITOGEN-ACTIVATED PROTEIN KINASE-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Prpf4b PhenoGen
PROSITE PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000016705 RatGTEx
  ENSRNOG00055013673 RatGTEx
  ENSRNOG00060009191 RatGTEx
  ENSRNOG00065008310 RatGTEx
SMART S_TKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K249_RAT UniProtKB/TrEMBL
  A0A8I6AEI6_RAT UniProtKB/TrEMBL
  A0A8L2QC63_RAT UniProtKB/TrEMBL
  A6J7F3 ENTREZGENE, UniProtKB/TrEMBL
  PRP4B_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-11-19 Prpf4b  pre-mRNA processing factor 4B  Prpf4b  PRP4 pre-mRNA processing factor 4 homolog B (yeast)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Prpf4b  PRP4 pre-mRNA processing factor 4 homolog B (yeast)  Prpf4b_predicted  PRP4 pre-mRNA processing factor 4 homolog B (yeast) (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Prpf4b_predicted  PRP4 pre-mRNA processing factor 4 homolog B (yeast) (predicted)      Symbol and Name status set to approved 70820 APPROVED