PRP4K (pre-mRNA processing factor kinase PRP4K) - Rat Genome Database

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Gene: PRP4K (pre-mRNA processing factor kinase PRP4K) Pan paniscus
Analyze
Symbol: PRP4K
Name: pre-mRNA processing factor kinase PRP4K
RGD ID: 12026286
Description: ENCODES a protein that exhibits 3-phosphoinositide-dependent protein kinase activity (inferred); AMP-activated protein kinase activity (inferred); ATP binding (inferred); INVOLVED IN chromatin remodeling (inferred); mRNA cis splicing, via spliceosome (inferred); positive regulation of hippo signaling (inferred); FOUND IN nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: pre-mRNA processing factor 4B; PRP4 pre-mRNA processing factor 4 homolog B; PRPF4B; serine/threonine-protein kinase PRP4 homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2518,648,631 - 18,691,933 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1614,649,258 - 14,695,425 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v063,854,844 - 3,898,185 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.164,044,456 - 4,088,226 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl64,044,610 - 4,085,148 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PRP4K
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2518,648,631 - 18,691,933 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1614,649,258 - 14,695,425 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v063,854,844 - 3,898,185 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.164,044,456 - 4,088,226 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl64,044,610 - 4,085,148 (+)Ensemblpanpan1.1panPan2
PRP4K
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3864,021,300 - 4,064,983 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl64,021,267 - 4,064,983 (+)EnsemblGRCh38hg38GRCh38
GRCh3764,021,534 - 4,065,217 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3663,966,568 - 4,010,216 (+)NCBINCBI36Build 36hg18NCBI36
Build 3463,966,594 - 4,010,215NCBI
Celera65,250,468 - 5,293,786 (+)NCBICelera
Cytogenetic Map6p25.2NCBI
HuRef63,898,364 - 3,941,580 (+)NCBIHuRef
CHM1_164,024,403 - 4,067,684 (+)NCBICHM1_1
T2T-CHM13v2.063,890,936 - 3,934,285 (+)NCBIT2T-CHM13v2.0
Prpf4b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391335,058,803 - 35,090,047 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1335,059,285 - 35,090,047 (+)EnsemblGRCm39 Ensembl
GRCm381334,874,820 - 34,906,064 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1334,875,302 - 34,906,064 (+)EnsemblGRCm38mm10GRCm38
MGSCv371334,967,363 - 34,994,747 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361334,882,961 - 34,910,497 (+)NCBIMGSCv36mm8
Celera1336,002,342 - 36,029,666 (+)NCBICelera
Cytogenetic Map13A3.3NCBI
cM Map1314.21NCBI
Prpf4b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81730,190,721 - 30,230,153 (-)NCBIGRCr8
mRatBN7.21729,985,343 - 30,020,285 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1729,985,343 - 30,019,625 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1729,813,167 - 29,844,178 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01731,416,901 - 31,447,908 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01729,808,887 - 29,839,898 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01730,680,454 - 30,714,542 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1730,683,640 - 30,714,495 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01732,580,447 - 32,614,537 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41736,319,606 - 36,350,616 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11736,322,446 - 36,353,457 (-)NCBI
Celera1729,558,539 - 29,589,473 (-)NCBICelera
Cytogenetic Map17p12NCBI
Prp4k
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554659,359,634 - 9,392,913 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554659,359,634 - 9,392,913 (-)NCBIChiLan1.0ChiLan1.0
PRP4K
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1354,274,664 - 4,311,813 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl354,271,685 - 4,307,750 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha354,284,298 - 4,321,450 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0354,336,704 - 4,373,868 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl354,336,715 - 4,370,715 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1354,211,834 - 4,248,986 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0354,233,455 - 4,270,536 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0355,567,860 - 5,605,013 (+)NCBIUU_Cfam_GSD_1.0
Prp4k
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494620,110,397 - 20,149,962 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365348,382,485 - 8,418,938 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365348,379,386 - 8,418,963 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRP4K
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl72,382,495 - 2,412,908 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.172,382,498 - 2,417,085 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.272,454,111 - 2,475,718 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PRP4K
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11768,110,544 - 68,153,939 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1768,114,973 - 68,153,844 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660443,972,241 - 4,015,978 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Prp4k
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475621,038,438 - 21,082,607 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003806704 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_003028258 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004671814 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004671815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004671816 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004671817 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004671818 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004671819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004671820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004671821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008625545 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008625547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008625548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008625549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008955723 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010112348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010112349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010112350 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010112351 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010112352 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010112353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010112354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010112355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010112356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010112357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010112358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010112359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010112360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010112361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010112362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010112363 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010112364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010112365 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010112366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010112367 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010112368 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_609313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSPPAT00000057560   ⟹   ENSPPAP00000034677
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl64,044,610 - 4,085,148 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000057565   ⟹   ENSPPAP00000034682
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl64,052,370 - 4,083,857 (+)Ensembl
RefSeq Acc Id: XM_003806704   ⟹   XP_003806752
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2518,648,631 - 18,691,933 (+)NCBI
NHGRI_mPanPan1614,649,258 - 14,692,347 (+)NCBI
Mhudiblu_PPA_v063,854,861 - 3,898,183 (+)NCBI
PanPan1.164,044,456 - 4,085,148 (+)NCBI
Sequence:
RefSeq Acc Id: XR_008625545
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2518,648,631 - 18,691,933 (+)NCBI
NHGRI_mPanPan1614,649,258 - 14,695,425 (+)NCBI
RefSeq Acc Id: XR_008625547
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2518,648,631 - 18,691,933 (+)NCBI
NHGRI_mPanPan1614,649,258 - 14,695,425 (+)NCBI
RefSeq Acc Id: XR_008625548
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2518,648,631 - 18,691,933 (+)NCBI
NHGRI_mPanPan1614,649,258 - 14,695,425 (+)NCBI
RefSeq Acc Id: XR_008625549
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2518,648,631 - 18,691,933 (+)NCBI
NHGRI_mPanPan1614,649,258 - 14,695,425 (+)NCBI
RefSeq Acc Id: XR_008955723
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2518,648,631 - 18,691,933 (+)NCBI
NHGRI_mPanPan1614,649,258 - 14,695,425 (+)NCBI
RefSeq Acc Id: XR_010112348
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2518,648,631 - 18,691,933 (+)NCBI
RefSeq Acc Id: XR_010112349
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2518,648,631 - 18,691,933 (+)NCBI
RefSeq Acc Id: XR_010112350
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2518,648,631 - 18,691,933 (+)NCBI
RefSeq Acc Id: XR_010112351
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2518,648,631 - 18,691,933 (+)NCBI
RefSeq Acc Id: XR_010112352
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2518,648,631 - 18,691,933 (+)NCBI
RefSeq Acc Id: XR_010112353
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2518,648,631 - 18,691,933 (+)NCBI
RefSeq Acc Id: XR_010112354
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2518,648,631 - 18,691,933 (+)NCBI
RefSeq Acc Id: XR_010112355
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2518,648,631 - 18,691,933 (+)NCBI
RefSeq Acc Id: XR_010112356
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2518,648,631 - 18,691,933 (+)NCBI
RefSeq Acc Id: XR_010112357
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2518,648,631 - 18,691,933 (+)NCBI
RefSeq Acc Id: XR_010112358
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2518,648,631 - 18,691,933 (+)NCBI
RefSeq Acc Id: XR_010112359
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2518,648,631 - 18,691,933 (+)NCBI
RefSeq Acc Id: XR_010112360
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2518,648,631 - 18,691,933 (+)NCBI
RefSeq Acc Id: XR_010112361
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2518,648,631 - 18,691,933 (+)NCBI
RefSeq Acc Id: XR_010112362
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2518,648,631 - 18,691,933 (+)NCBI
RefSeq Acc Id: XR_010112363
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2518,648,631 - 18,691,933 (+)NCBI
RefSeq Acc Id: XR_010112364
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2518,648,631 - 18,691,933 (+)NCBI
RefSeq Acc Id: XR_010112365
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2518,648,631 - 18,691,933 (+)NCBI
RefSeq Acc Id: XR_010112366
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2518,648,631 - 18,691,933 (+)NCBI
RefSeq Acc Id: XR_010112367
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2518,648,631 - 18,691,933 (+)NCBI
RefSeq Acc Id: XR_010112368
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2518,648,631 - 18,691,933 (+)NCBI
Protein Sequences
Protein RefSeqs XP_003806752 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000034677
  ENSPPAP00000034677.1
  ENSPPAP00000034682.1
RefSeq Acc Id: XP_003806752   ⟸   XM_003806704
- UniProtKB: A0A2R9BYC3 (UniProtKB/TrEMBL),   A0A2R9BYC8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000034677   ⟸   ENSPPAT00000057560
Ensembl Acc Id: ENSPPAP00000034682   ⟸   ENSPPAT00000057565
Protein Domains
Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000040144 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000057560.1 UniProtKB/TrEMBL
  ENSPPAT00000057565.1 UniProtKB/TrEMBL
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
  Ser_Thr_dual-spec_kinase UniProtKB/TrEMBL
  STKc_PRP4 UniProtKB/TrEMBL
KEGG Report pps:100974029 UniProtKB/TrEMBL
NCBI Gene PRPF4B ENTREZGENE
PANTHER DUAL SPECIFICITY PROTEIN KINASE UniProtKB/TrEMBL
  MITOGEN-ACTIVATED PROTEIN KINASE-RELATED UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A2R9BYC3 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BYC8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-12-26 PRP4K  pre-mRNA processing factor kinase PRP4K  PRPF4B  pre-mRNA processing factor 4B  Symbol and/or name change 5135510 APPROVED