Akr1c3 Rat (-)-epigallocatechin 3-gallate multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of AKR1C3 mRNA CTD PMID:22079256 Akr1c3 Rat (20S)-20-hydroxypregn-4-en-3-one multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in increased metabolism of Progesterone] which results in increased chemical synthesis of more ... CTD PMID:19010312|PMID:20036328 Akr1c3 Rat (20S)-20-hydroxypregn-4-en-3-one increases chemical synthesis EXP 6480464 AKR1C18 protein results in increased chemical synthesis of 20-alpha-Dihydroprogesterone CTD PMID:8172618 Akr1c3 Rat (20S)-20-hydroxypregn-4-en-3-one increases chemical synthesis ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased chemical synthesis of 20-alpha-Dihydroprogesterone CTD PMID:25463305 Akr1c3 Rat (E)-cinnamyl alcohol increases expression ISO AKR1C3 (Homo sapiens) 6480464 cinnamyl alcohol results in increased expression of AKR1C3 mRNA CTD PMID:20566472 Akr1c3 Rat (S)-naringenin decreases activity ISO AKR1C3 (Homo sapiens) 6480464 naringenin results in decreased activity of AKR1C3 protein CTD PMID:19007764 Akr1c3 Rat 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane multiple interactions EXP 6480464 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [FSHB protein affects the expression of AKR1C18 mRNA] CTD PMID:19414516 Akr1c3 Rat 1,10-phenanthroline decreases activity ISO AKR1C3 (Homo sapiens) 6480464 1,10-phenanthroline results in decreased activity of AKR1C3 protein CTD PMID:12604236 Akr1c3 Rat 1,2-dichloroethane increases expression ISO Akr1c18 (Mus musculus) 6480464 ethylene dichloride results in increased expression of AKR1C18 mRNA CTD PMID:28960355 Akr1c3 Rat 1,2-dimethylhydrazine decreases expression ISO Akr1c18 (Mus musculus) 6480464 1,2-Dimethylhydrazine results in decreased expression of AKR1C18 mRNA CTD PMID:22206623 Akr1c3 Rat 1,8-Dinitropyrene multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in increased degradation of 1,8-dinitropyrene] which results in increased abundance of 1-amino-8-nitropyrene CTD PMID:36399404 Akr1c3 Rat 1-Aminopyrene multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in increased degradation of 1-nitropyrene] which results in increased abundance of 1-aminopyrene CTD PMID:36399404 Akr1c3 Rat 1-chloro-2,4-dinitrobenzene increases expression ISO AKR1C3 (Homo sapiens) 6480464 Dinitrochlorobenzene results in increased expression of AKR1C3 mRNA CTD PMID:20566472 Akr1c3 Rat 1-chloro-2,4-dinitrobenzene affects expression ISO Akr1c18 (Mus musculus) 6480464 Dinitrochlorobenzene affects the expression of AKR1C18 mRNA CTD PMID:22302311 Akr1c3 Rat 1-naphthyl isothiocyanate decreases expression EXP 6480464 1-Naphthylisothiocyanate results in decreased expression of AKR1C3 mRNA CTD PMID:25380136|PMID:30723492 Akr1c3 Rat 1-nitropyrene multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in increased degradation of 1-nitropyrene] which results in increased abundance of 1-aminopyrene CTD PMID:36399404 Akr1c3 Rat 11-deoxycorticosterone increases metabolic processing ISO Akr1c18 (Mus musculus) 6480464 AKR1C18 protein results in increased metabolism of Desoxycorticosterone CTD PMID:17122075 Akr1c3 Rat 13-dihydrodaunorubicin multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in increased metabolism of Daunorubicin] which results in increased abundance of daunorubicinol; more ... CTD PMID:30703376|PMID:32588086|PMID:33025066|PMID:35972551 Akr1c3 Rat 13-dihydrodaunorubicin increases chemical synthesis ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased chemical synthesis of daunorubicinol CTD PMID:33025066 Akr1c3 Rat 15-deoxy-Delta(12,14)-prostaglandin J2 multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [Medroxyprogesterone Acetate inhibits the reaction [[AKR1C3 protein results in increased metabolism of Prostaglandin D2] which more ... CTD PMID:19997560 Akr1c3 Rat 17beta-estradiol multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in increased metabolism of Estrone] which results in increased chemical synthesis of more ... CTD PMID:19010312|PMID:19619570|PMID:20036328 Akr1c3 Rat 17beta-estradiol decreases expression ISO Akr1c18 (Mus musculus) 6480464 Estradiol results in decreased expression of AKR1C18 mRNA CTD PMID:39298647 Akr1c3 Rat 17beta-estradiol increases expression ISO Akr1c18 (Mus musculus) 6480464 Estradiol results in increased expression of AKR1C18 mRNA CTD PMID:19484750 Akr1c3 Rat 17beta-estradiol decreases expression ISO AKR1C3 (Homo sapiens) 6480464 Estradiol results in decreased expression of AKR1C3 mRNA CTD PMID:19619570|PMID:23019147|PMID:31614463 Akr1c3 Rat 17beta-hydroxy-5alpha-androstan-3-one multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in increased metabolism of Androstenedione] which results in increased chemical synthesis of more ... CTD PMID:14672942|PMID:19010312 Akr1c3 Rat 17beta-hydroxy-5alpha-androstan-3-one increases metabolic processing ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased metabolism of Dihydrotestosterone CTD PMID:14672942 Akr1c3 Rat 2,2',4,4',5,5'-hexachlorobiphenyl increases expression ISO AKR1C3 (Homo sapiens) 6480464 2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of AKR1C3 mRNA CTD PMID:38568856 Akr1c3 Rat 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of AKR1C3 mRNA CTD PMID:19619570 Akr1c3 Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Akr1c18 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of AKR1C18 mRNA CTD PMID:28922406 Akr1c3 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Akr1c18 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of AKR1C18 mRNA CTD PMID:21570461 Akr1c3 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of AKR1C3 mRNA CTD PMID:21215274 Akr1c3 Rat 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 AHR protein alternative form affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of AKR1C3 mRNA] CTD PMID:21215274 Akr1c3 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO AKR1C3 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in decreased expression of AKR1C3 mRNA CTD PMID:19619570 Akr1c3 Rat 2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expression ISO Akr1c18 (Mus musculus) 6480464 2,2',4,4',5-brominated diphenyl ether affects the expression of AKR1C18 mRNA CTD PMID:38648751 Akr1c3 Rat 2-amino-14,16-dimethyloctadecan-3-ol decreases expression ISO AKR1C3 (Homo sapiens) 6480464 2-amino-14,16-dimethyloctadecan-3-ol results in decreased expression of AKR1C3 protein CTD PMID:32044396 Akr1c3 Rat 2-hydroxyethyl methacrylate increases expression ISO AKR1C3 (Homo sapiens) 6480464 hydroxyethyl methacrylate results in increased expression of AKR1C3 mRNA CTD PMID:30497689 Akr1c3 Rat 2-hydroxypropanoic acid increases expression ISO AKR1C3 (Homo sapiens) 6480464 Lactic Acid results in increased expression of AKR1C3 mRNA CTD PMID:20566472 Akr1c3 Rat 2-methoxyethanol multiple interactions EXP 6480464 methyl cellosolve inhibits the reaction [Bromocriptine results in increased expression of AKR1C3 mRNA] CTD PMID:21427058 Akr1c3 Rat 2-methoxyethanol decreases expression EXP 6480464 methyl cellosolve results in decreased expression of AKR1C3 mRNA CTD PMID:21427058 Akr1c3 Rat 20-hydroxypregn-4-en-3-one increases chemical synthesis ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased chemical synthesis of 3-hydroxypregn-4-en-20-one CTD PMID:25463305 Akr1c3 Rat 3,3',5-triiodo-L-thyronine increases expression ISO AKR1C3 (Homo sapiens) 6480464 Triiodothyronine results in increased expression of AKR1C3 mRNA CTD PMID:15507505 Akr1c3 Rat 3,4-dichloroaniline increases expression ISO AKR1C3 (Homo sapiens) 6480464 3,4-dichloroaniline results in increased expression of AKR1C3 mRNA CTD PMID:24172598 Akr1c3 Rat 3,4-methylenedioxymethamphetamine decreases expression ISO Akr1c18 (Mus musculus) 6480464 N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of AKR1C18 mRNA CTD PMID:20188158 Akr1c3 Rat 3-chloropropane-1,2-diol decreases expression EXP 6480464 alpha-Chlorohydrin results in decreased expression of AKR1C3 protein CTD PMID:34915118 Akr1c3 Rat 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression more ... CTD PMID:28628672 Akr1c3 Rat 3-Nitrobenzanthrone increases reduction ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased reduction of 3-nitrobenzanthrone CTD PMID:30406992 Akr1c3 Rat 3-Nitrobenzanthrone multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in increased reduction of 3-nitrobenzanthrone] which results in increased chemical synthesis of more ... CTD PMID:30406992 Akr1c3 Rat 3alpha-hydroxy-5beta-pregnan-20-one increases chemical synthesis ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased chemical synthesis of Pregnanolone CTD PMID:25463305 Akr1c3 Rat 4,4'-diaminodiphenylmethane decreases expression EXP 6480464 4,4'-diaminodiphenylmethane results in decreased expression of AKR1C3 mRNA CTD PMID:25380136 Akr1c3 Rat 4,4'-diaminodiphenylmethane increases expression ISO Akr1c18 (Mus musculus) 6480464 4,4'-diaminodiphenylmethane results in increased expression of AKR1C18 mRNA CTD PMID:18648102 Akr1c3 Rat 4,4'-sulfonyldiphenol decreases expression ISO AKR1C3 (Homo sapiens) 6480464 bisphenol S results in decreased expression of AKR1C3 mRNA CTD PMID:38568856 Akr1c3 Rat 4-hydroxybenzoic acid decreases activity ISO AKR1C3 (Homo sapiens) 6480464 4-hydroxybenzoic acid analog results in decreased activity of AKR1C3 protein CTD PMID:27163852 Akr1c3 Rat 4-hydroxynon-2-enal multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 7-hydroxycoumarin inhibits the reaction [AKR1C3 mutant form results in increased susceptibility to 4-hydroxy-2-nonenal] CTD PMID:22964423 Akr1c3 Rat 4-hydroxynon-2-enal increases expression ISO AKR1C3 (Homo sapiens) 6480464 4-hydroxy-2-nonenal results in increased expression of AKR1C3 mRNA; 4-hydroxy-2-nonenal results in increased expression of AKR1C3 more ... CTD PMID:22964423|PMID:30849339 Akr1c3 Rat 4-hydroxynon-2-enal increases response to substance ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 mutant form results in increased susceptibility to 4-hydroxy-2-nonenal CTD PMID:22964423 Akr1c3 Rat 4-hydroxyphenyl retinamide decreases expression ISO Akr1c18 (Mus musculus) 6480464 Fenretinide results in decreased expression of AKR1C3 mRNA CTD PMID:28973697 Akr1c3 Rat 5-fluorouracil affects expression ISO AKR1C3 (Homo sapiens) 6480464 Fluorouracil affects the expression of AKR1C3 mRNA CTD PMID:16584549 Akr1c3 Rat 5-fluorouracil affects response to substance ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 Akr1c3 Rat 5alpha-Pregnan-20alpha-ol-3-one increases chemical synthesis ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased chemical synthesis of allopregnan-20 alpha-ol-3-one CTD PMID:25463305 Akr1c3 Rat 5alpha-pregnane-3,20-dione increases chemical synthesis ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased chemical synthesis of 5-alpha-Dihydroprogesterone CTD PMID:25463305 Akr1c3 Rat 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of AKR1C18 mRNA CTD PMID:24780913 Akr1c3 Rat 7-hydroxyflavone decreases activity ISO AKR1C3 (Homo sapiens) 6480464 7-hydroxyflavone results in decreased activity of AKR1C3 protein CTD PMID:19007764 Akr1c3 Rat 9,10-phenanthroquinone increases metabolic processing ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased metabolism of 9,10-phenanthrenequinone CTD PMID:17950253|PMID:29108775 Akr1c3 Rat 9,10-phenanthroquinone increases reduction ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased reduction of 9,10-phenanthrenequinone CTD PMID:19442656|PMID:21851338|PMID:23261716 Akr1c3 Rat 9,10-phenanthroquinone increases expression ISO AKR1C3 (Homo sapiens) 6480464 9,10-phenanthrenequinone results in increased expression of AKR1C3 protein CTD PMID:29108775 Akr1c3 Rat 9,10-phenanthroquinone multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in increased reduction of 9,10-phenanthrenequinone] which results in increased abundance of Superoxides; more ... CTD PMID:17950253|PMID:19442656|PMID:21910479 Akr1c3 Rat 9-cis-retinal increases reduction ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein mutant form results in increased reduction of 9-cis-retinal; AKR1C3 protein results in increased more ... CTD PMID:21851338 Akr1c3 Rat acetylsalicylic acid decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Aspirin results in decreased activity of AKR1C3 protein CTD PMID:19010312 Akr1c3 Rat acrolein multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ... CTD PMID:32699268 Akr1c3 Rat actinomycin D multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [Dactinomycin co-treated with nutlin 3] results in increased secretion of AKR1C3 protein CTD PMID:38460933 Akr1c3 Rat aldehydo-D-glucose multiple interactions ISO Akr1c18 (Mus musculus) 6480464 [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] more ... CTD PMID:37567420 Akr1c3 Rat all-trans-retinal increases reduction ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased reduction of Retinaldehyde CTD PMID:23261716 Akr1c3 Rat all-trans-retinoic acid increases expression ISO AKR1C3 (Homo sapiens) 6480464 Tretinoin results in increased expression of AKR1C3 mRNA CTD PMID:23724009|PMID:33167477 Akr1c3 Rat all-trans-retinoic acid multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [Tretinoin results in decreased activity of AKR1C3 protein] which results in increased susceptibility to Daunorubicin; more ... CTD PMID:32588086 Akr1c3 Rat Aloe emodin decreases activity ISO AKR1C3 (Homo sapiens) 6480464 aloe emodin results in decreased activity of AKR1C3 protein CTD PMID:35065925 Akr1c3 Rat alpha-hexylcinnamaldehyde increases expression ISO AKR1C3 (Homo sapiens) 6480464 hexyl cinnamic aldehyde results in increased expression of AKR1C3 mRNA CTD PMID:20566472 Akr1c3 Rat alpha-hexylcinnamaldehyde affects expression ISO Akr1c18 (Mus musculus) 6480464 hexyl cinnamic aldehyde affects the expression of AKR1C18 mRNA CTD PMID:22302311 Akr1c3 Rat alpha-pinene multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ... CTD PMID:32699268 Akr1c3 Rat alpha-Zearalanol multiple interactions EXP 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of AKR1C3 mRNA CTD PMID:35163327 Akr1c3 Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of AKR1C18 mRNA CTD PMID:16483693 Akr1c3 Rat androst-4-ene-3,17-dione increases metabolic processing ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased metabolism of Androstenedione CTD PMID:19010312 Akr1c3 Rat androst-4-ene-3,17-dione increases reduction ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased reduction of Androstenedione CTD PMID:17950253|PMID:20036328 Akr1c3 Rat androst-4-ene-3,17-dione multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in increased metabolism of Androstenedione] which results in increased chemical synthesis of more ... CTD PMID:17950253|PMID:19010312|PMID:20036328 Akr1c3 Rat antimonite multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of more ... CTD PMID:32076005 Akr1c3 Rat antirheumatic drug increases expression ISO AKR1C3 (Homo sapiens) 6480464 Antirheumatic Agents results in increased expression of AKR1C3 mRNA CTD PMID:24449571 Akr1c3 Rat arsane multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of AKR1C3 more ... CTD PMID:32525701 Akr1c3 Rat arsane increases expression ISO AKR1C3 (Homo sapiens) 6480464 Arsenic results in increased expression of AKR1C3 mRNA CTD PMID:36861143 Akr1c3 Rat arsenic acid multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of arsenic acid] which results in increased expression of more ... CTD PMID:38630284 Akr1c3 Rat arsenic atom multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of AKR1C3 more ... CTD PMID:32525701 Akr1c3 Rat arsenic atom increases expression ISO AKR1C3 (Homo sapiens) 6480464 Arsenic results in increased expression of AKR1C3 mRNA CTD PMID:36861143 Akr1c3 Rat arsenite(3-) multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [sodium arsenite results in increased abundance of arsenite] which results in increased expression of AKR1C3 more ... CTD PMID:32076005|PMID:38630284 Akr1c3 Rat arsenous acid multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to AKR1C3 protein] CTD PMID:26598702 Akr1c3 Rat arsenous acid increases expression ISO AKR1C3 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of AKR1C3 mRNA CTD PMID:19128835|PMID:21461292|PMID:26705709 Akr1c3 Rat arsenous acid decreases response to substance ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in decreased susceptibility to Arsenic Trioxide CTD PMID:20707922 Akr1c3 Rat atrazine decreases expression EXP 6480464 Atrazine results in decreased expression of AKR1C3 mRNA CTD PMID:21427058 Akr1c3 Rat avobenzone increases expression ISO AKR1C3 (Homo sapiens) 6480464 avobenzone results in increased expression of AKR1C3 mRNA CTD PMID:31016361 Akr1c3 Rat Azoxymethane multiple interactions ISO Akr1c18 (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of AKR1C18 more ... CTD PMID:29950665 Akr1c3 Rat Bandrowski's base increases expression ISO AKR1C3 (Homo sapiens) 6480464 Bandrowski's base results in increased expression of AKR1C3 mRNA CTD PMID:20566472 Akr1c3 Rat benzbromarone decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Benzbromarone results in decreased activity of AKR1C3 protein CTD PMID:12604236 Akr1c3 Rat benzo[a]pyrene multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [Butyric Acid co-treated with Benzo(a)pyrene] results in increased expression of AKR1C3 mRNA; [Particulate Matter co-treated more ... CTD PMID:17612574|PMID:30439556 Akr1c3 Rat benzo[a]pyrene decreases expression ISO AKR1C3 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of AKR1C3 mRNA CTD PMID:30439556 Akr1c3 Rat benzo[a]pyrene decreases expression ISO Akr1c18 (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of AKR1C18 mRNA CTD PMID:22228805 Akr1c3 Rat benzo[a]pyrene increases expression ISO AKR1C3 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of AKR1C3 mRNA; Benzo(a)pyrene results in increased expression of AKR1C3 more ... CTD PMID:20106945|PMID:21632981|PMID:22316170|PMID:26238291|PMID:30439556|PMID:33278487 Akr1c3 Rat Benzo[a]pyrene-7,8-diol multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein co-treated with NADP] results in increased oxidation of and affects the activity of more ... CTD PMID:21910479 Akr1c3 Rat benzo[a]pyrene-7,8-dione multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein co-treated with NADP] results in increased reduction of and affects the activity of more ... CTD PMID:21910479 Akr1c3 Rat benzo[e]pyrene increases methylation ISO AKR1C3 (Homo sapiens) 6480464 benzo(e)pyrene results in increased methylation of AKR1C3 intron CTD PMID:30157460 Akr1c3 Rat benzoic acid increases expression ISO AKR1C3 (Homo sapiens) 6480464 Benzoic Acid results in increased expression of AKR1C3 mRNA CTD PMID:20566472 Akr1c3 Rat beta-lapachone increases expression ISO AKR1C3 (Homo sapiens) 6480464 beta-lapachone results in increased expression of AKR1C3 mRNA CTD PMID:38218311 Akr1c3 Rat beta-naphthoflavone increases expression ISO AKR1C3 (Homo sapiens) 6480464 beta-Naphthoflavone results in increased expression of AKR1C3 mRNA; beta-Naphthoflavone results in increased expression of AKR1C3 more ... CTD PMID:19737606|PMID:32151702|PMID:39638853 Akr1c3 Rat beta-naphthoflavone multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of AKR1C18 mRNA CTD PMID:18164116 Akr1c3 Rat bexarotene increases expression ISO AKR1C3 (Homo sapiens) 6480464 bexarotene results in increased expression of AKR1C3 mRNA CTD PMID:17178900 Akr1c3 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of AKR1C3 mRNA CTD PMID:25181051 Akr1c3 Rat bisphenol A increases methylation ISO AKR1C3 (Homo sapiens) 6480464 bisphenol A results in increased methylation of AKR1C3 gene CTD PMID:31601247 Akr1c3 Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of AKR1C3 mRNA CTD PMID:32145629 Akr1c3 Rat bisphenol A affects expression ISO AKR1C3 (Homo sapiens) 6480464 bisphenol A affects the expression of AKR1C3 mRNA CTD PMID:30903817 Akr1c3 Rat bisphenol AF increases expression ISO AKR1C3 (Homo sapiens) 6480464 bisphenol AF results in increased expression of AKR1C3 protein CTD PMID:34186270 Akr1c3 Rat Bisphenol B increases expression ISO AKR1C3 (Homo sapiens) 6480464 bisphenol B results in increased expression of AKR1C3 protein CTD PMID:34186270 Akr1c3 Rat bisphenol F increases expression ISO AKR1C3 (Homo sapiens) 6480464 bisphenol F results in increased expression of AKR1C3 protein CTD PMID:34186270 Akr1c3 Rat bortezomib increases expression ISO AKR1C3 (Homo sapiens) 6480464 Bortezomib results in increased expression of AKR1C3 mRNA CTD PMID:21215737 Akr1c3 Rat Bromazepam decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Bromazepam results in decreased activity of AKR1C3 protein CTD PMID:11995921 Akr1c3 Rat bromocriptine increases expression EXP 6480464 Bromocriptine results in increased expression of AKR1C3 mRNA CTD PMID:21427058 Akr1c3 Rat bromocriptine multiple interactions EXP 6480464 methyl cellosolve inhibits the reaction [Bromocriptine results in increased expression of AKR1C3 mRNA] CTD PMID:21427058 Akr1c3 Rat butan-1-ol multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic more ... CTD PMID:29432896 Akr1c3 Rat butyric acid increases expression ISO AKR1C3 (Homo sapiens) 6480464 Butyric Acid results in increased expression of AKR1C3 mRNA CTD PMID:30439556 Akr1c3 Rat butyric acid multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [Butyric Acid co-treated with Benzo(a)pyrene] results in increased expression of AKR1C3 mRNA; Benzo(a)pyrene promotes the more ... CTD PMID:30439556 Akr1c3 Rat cadmium acetate increases expression ISO AKR1C3 (Homo sapiens) 6480464 cadmium acetate results in increased expression of AKR1C3 mRNA; cadmium acetate results in increased expression more ... CTD PMID:21787718 Akr1c3 Rat cadmium acetate multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cadmium acetate results in increased expression of AKR1C3 protein]; Acetylcysteine inhibits more ... CTD PMID:21787718 Akr1c3 Rat cadmium atom increases expression ISO AKR1C3 (Homo sapiens) 6480464 Cadmium results in increased expression of AKR1C3 mRNA CTD PMID:21120746 Akr1c3 Rat cadmium atom multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of AKR1C3 more ... CTD PMID:29741670|PMID:31738976|PMID:35301059 Akr1c3 Rat cadmium atom decreases expression ISO Akr1c18 (Mus musculus) 6480464 Cadmium results in decreased expression of AKR1C18 mRNA CTD PMID:24067728 Akr1c3 Rat cadmium dichloride multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of AKR1C3 more ... CTD PMID:29741670|PMID:31738976|PMID:35301059 Akr1c3 Rat cadmium dichloride increases expression ISO AKR1C3 (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of AKR1C3 mRNA CTD PMID:38568856 Akr1c3 Rat capecitabine increases response to substance ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased susceptibility to Capecitabine CTD PMID:16734730 Akr1c3 Rat carbamazepine affects expression ISO AKR1C3 (Homo sapiens) 6480464 Carbamazepine affects the expression of AKR1C3 mRNA CTD PMID:25979313 Akr1c3 Rat carbon nanotube decreases expression ISO Akr1c18 (Mus musculus) 6480464 Nanotubes, Carbon results in decreased expression of AKR1C18 mRNA CTD PMID:25620056 Akr1c3 Rat CGP 52608 multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to AKR1C3 gene] CTD PMID:28238834 Akr1c3 Rat choline multiple interactions ISO Akr1c18 (Mus musculus) 6480464 [Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in increased expression more ... CTD PMID:20938992|PMID:29127188 Akr1c3 Rat chromium(6+) multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [zinc chromate results in increased abundance of chromium hexavalent ion] which results in increased expression more ... CTD PMID:38479592 Akr1c3 Rat cinnamyl alcohol increases expression ISO AKR1C3 (Homo sapiens) 6480464 cinnamyl alcohol results in increased expression of AKR1C3 mRNA CTD PMID:20566472 Akr1c3 Rat cisplatin increases expression ISO AKR1C3 (Homo sapiens) 6480464 Cisplatin results in increased expression of AKR1C3 mRNA; Cisplatin results in increased expression of AKR1C3 more ... CTD PMID:23165153|PMID:27392435 Akr1c3 Rat cisplatin multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of AKR1C3 mRNA; [Cisplatin results in increased more ... CTD PMID:23165153|PMID:27392435 Akr1c3 Rat cisplatin decreases response to substance ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in decreased susceptibility to Cisplatin CTD PMID:23165153 Akr1c3 Rat Clofop increases reduction ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased reduction of fenofibric acid CTD PMID:27599626 Akr1c3 Rat cloxazolam decreases activity ISO AKR1C3 (Homo sapiens) 6480464 cloxazolam results in decreased activity of AKR1C3 protein CTD PMID:11995921|PMID:12604236 Akr1c3 Rat cobalt dichloride decreases expression ISO AKR1C3 (Homo sapiens) 6480464 cobaltous chloride results in decreased expression of AKR1C3 mRNA CTD PMID:17553155 Akr1c3 Rat colforsin daropate hydrochloride decreases expression ISO AKR1C3 (Homo sapiens) 6480464 Colforsin results in decreased expression of AKR1C3 mRNA CTD PMID:28235592 Akr1c3 Rat coniferyl aldehyde increases expression ISO AKR1C3 (Homo sapiens) 6480464 coniferaldehyde results in increased expression of AKR1C3 mRNA CTD PMID:26275128 Akr1c3 Rat copper atom multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [NSC 689534 binds to Copper] which results in increased expression of AKR1C3 mRNA CTD PMID:20971185 Akr1c3 Rat copper(0) multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [NSC 689534 binds to Copper] which results in increased expression of AKR1C3 mRNA CTD PMID:20971185 Akr1c3 Rat copper(II) chloride increases expression ISO AKR1C3 (Homo sapiens) 6480464 cupric chloride results in increased expression of AKR1C3 mRNA CTD PMID:38568856 Akr1c3 Rat copper(II) sulfate increases expression ISO AKR1C3 (Homo sapiens) 6480464 Copper Sulfate results in increased expression of AKR1C3 mRNA CTD PMID:19549813 Akr1c3 Rat crotonaldehyde increases expression ISO AKR1C3 (Homo sapiens) 6480464 2-butenal results in increased expression of AKR1C3 mRNA CTD PMID:20471460 Akr1c3 Rat cycloheximide multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 Cycloheximide inhibits the reaction [cadmium acetate results in increased expression of AKR1C3 protein] CTD PMID:21787718 Akr1c3 Rat cyclopentanol increases oxidation ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased oxidation of cyclopentanol CTD PMID:23261716 Akr1c3 Rat cyclopentanone multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein co-treated with NADP] results in increased reduction of cyclopentanone; Medroxyprogesterone Acetate inhibits the more ... CTD PMID:23261716 Akr1c3 Rat cyclopentanone increases reduction ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased reduction of cyclopentanone CTD PMID:23261716 Akr1c3 Rat cyclosporin A decreases expression ISO AKR1C3 (Homo sapiens) 6480464 Cyclosporine results in decreased expression of AKR1C3 mRNA CTD PMID:25562108|PMID:33631201 Akr1c3 Rat cyclosporin A decreases expression EXP 6480464 Cyclosporine results in decreased expression of AKR1C18 mRNA CTD PMID:21865292 Akr1c3 Rat D-glucose multiple interactions ISO Akr1c18 (Mus musculus) 6480464 [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] more ... CTD PMID:37567420 Akr1c3 Rat daunorubicin increases metabolic processing ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased metabolism of Daunorubicin; AKR1C3 results in increased metabolism of Daunorubicin CTD PMID:20837989|PMID:32588086|PMID:33025066 Akr1c3 Rat daunorubicin increases reduction ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased reduction of Daunorubicin CTD PMID:33025066|PMID:35972551 Akr1c3 Rat daunorubicin multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in increased metabolism of Daunorubicin] which results in increased abundance of daunorubicinol; more ... CTD PMID:29992508|PMID:30703376|PMID:32588086|PMID:33025066|PMID:35972551 Akr1c3 Rat daunorubicin decreases response to substance ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in decreased susceptibility to Daunorubicin CTD PMID:29992508|PMID:33025066|PMID:35972551 Akr1c3 Rat DDE decreases expression ISO AKR1C3 (Homo sapiens) 6480464 Dichlorodiphenyl Dichloroethylene results in decreased expression of AKR1C3 mRNA CTD PMID:38568856 Akr1c3 Rat deguelin increases expression ISO AKR1C3 (Homo sapiens) 6480464 deguelin results in increased expression of AKR1C3 mRNA CTD PMID:33512557 Akr1c3 Rat dehydroepiandrosterone affects metabolic processing EXP 6480464 AKR1C18 protein affects the metabolism of Dehydroepiandrosterone CTD PMID:15261307 Akr1c3 Rat desogestrel decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Desogestrel results in decreased activity of AKR1C3 protein CTD PMID:21182831 Akr1c3 Rat dexamethasone increases expression ISO AKR1C3 (Homo sapiens) 6480464 Dexamethasone results in increased expression of AKR1C3 mRNA CTD PMID:25047013 Akr1c3 Rat dexamethasone multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression more ... CTD PMID:28628672 Akr1c3 Rat dextran sulfate multiple interactions ISO Akr1c18 (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of AKR1C18 more ... CTD PMID:29950665 Akr1c3 Rat diarsenic trioxide multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to AKR1C3 protein] CTD PMID:26598702 Akr1c3 Rat diarsenic trioxide decreases response to substance ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in decreased susceptibility to Arsenic Trioxide CTD PMID:20707922 Akr1c3 Rat diarsenic trioxide increases expression ISO AKR1C3 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of AKR1C3 mRNA CTD PMID:19128835|PMID:21461292|PMID:26705709 Akr1c3 Rat diazepam decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Diazepam results in decreased activity of AKR1C3 protein CTD PMID:11995921|PMID:12604236 Akr1c3 Rat dibenzo[a,l]pyrene multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [Particulate Matter co-treated with dibenzo(a,l)pyrene] results in increased expression of AKR1C3 mRNA; [Vehicle Emissions co-treated more ... CTD PMID:17612574 Akr1c3 Rat Dibutyl phosphate affects expression ISO AKR1C3 (Homo sapiens) 6480464 di-n-butylphosphoric acid affects the expression of AKR1C3 mRNA CTD PMID:37042841 Akr1c3 Rat dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of AKR1C18 mRNA CTD PMID:21266533 Akr1c3 Rat dicrotophos decreases expression ISO AKR1C3 (Homo sapiens) 6480464 dicrotophos results in decreased expression of AKR1C3 mRNA CTD PMID:28302478 Akr1c3 Rat diethylstilbestrol increases expression ISO Akr1c18 (Mus musculus) 6480464 Diethylstilbestrol results in increased expression of AKR1C3 mRNA CTD PMID:19665456 Akr1c3 Rat diethylstilbestrol multiple interactions ISO Akr1c18 (Mus musculus) 6480464 sodium arsenite promotes the reaction [Diethylstilbestrol results in increased expression of AKR1C3 mRNA] CTD PMID:19665456 Akr1c3 Rat dimethylarsinic acid increases expression ISO AKR1C3 (Homo sapiens) 6480464 Cacodylic Acid results in increased expression of AKR1C3 mRNA CTD PMID:38630284 Akr1c3 Rat dinaciclib multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 dinaciclib binds to and results in decreased activity of AKR1C3 protein; dinaciclib inhibits the reaction more ... CTD PMID:29992508 Akr1c3 Rat dioxygen multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in increased reduction of and affects the activity of benzo(a)pyrene-3,6-quinone] which results more ... CTD PMID:21910479 Akr1c3 Rat dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate increases expression ISO AKR1C3 (Homo sapiens) 6480464 Antimony Potassium Tartrate results in increased expression of AKR1C3 mRNA; Antimony Potassium Tartrate results in more ... CTD PMID:28713220 Akr1c3 Rat dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of more ... CTD PMID:32076005 Akr1c3 Rat disulfiram increases expression ISO AKR1C3 (Homo sapiens) 6480464 Disulfiram results in increased expression of AKR1C3 mRNA CTD PMID:20566472 Akr1c3 Rat diuron increases expression ISO AKR1C3 (Homo sapiens) 6480464 Diuron metabolite results in increased expression of AKR1C3 mRNA CTD PMID:24172598 Akr1c3 Rat dorsomorphin multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Akr1c3 Rat doxifluridine increases response to substance ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased susceptibility to doxifluridine CTD PMID:16734730 Akr1c3 Rat doxorubicin affects reduction ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein affects the reduction of Doxorubicin CTD PMID:18635746 Akr1c3 Rat doxorubicin decreases expression ISO AKR1C3 (Homo sapiens) 6480464 Doxorubicin results in decreased expression of AKR1C3 mRNA CTD PMID:29803840 Akr1c3 Rat doxorubicin increases metabolic processing ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 results in increased metabolism of Doxorubicin CTD PMID:20837989 Akr1c3 Rat dutasteride increases expression ISO AKR1C3 (Homo sapiens) 6480464 Dutasteride results in increased expression of AKR1C3 mRNA CTD PMID:16806904 Akr1c3 Rat dydrogesterone decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Dydrogesterone results in decreased activity of AKR1C3 protein CTD PMID:21182831 Akr1c3 Rat dydrogesterone decreases expression ISO AKR1C3 (Homo sapiens) 6480464 Dydrogesterone results in decreased expression of AKR1C3 mRNA CTD PMID:23183084 Akr1c3 Rat emodin decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Emodin results in decreased activity of AKR1C3 protein CTD PMID:35065925 Akr1c3 Rat enasidenib multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 enasidenib inhibits the reaction [[AKR1C3 protein results in increased reduction of Daunorubicin] which results in more ... CTD PMID:35972551 Akr1c3 Rat enasidenib decreases activity ISO AKR1C3 (Homo sapiens) 6480464 enasidenib results in decreased activity of AKR1C3 protein CTD PMID:35972551 Akr1c3 Rat estazolam decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Estazolam results in decreased activity of AKR1C3 protein CTD PMID:11995921 Akr1c3 Rat estrone increases metabolic processing ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased metabolism of Estrone CTD PMID:19010312 Akr1c3 Rat estrone increases reduction ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased reduction of Estrone CTD PMID:20036328 Akr1c3 Rat estrone multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in increased metabolism of Estrone] which results in increased chemical synthesis of more ... CTD PMID:19010312|PMID:20036328 Akr1c3 Rat ethanol multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic more ... CTD PMID:29432896 Akr1c3 Rat ethylparaben increases expression ISO AKR1C3 (Homo sapiens) 6480464 ethyl-p-hydroxybenzoate results in increased expression of AKR1C3 mRNA CTD PMID:37690743 Akr1c3 Rat eugenol increases expression ISO AKR1C3 (Homo sapiens) 6480464 Eugenol results in increased expression of AKR1C3 mRNA CTD PMID:20566472 Akr1c3 Rat farnesal increases reduction ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased reduction of farnesal CTD PMID:21187079 Akr1c3 Rat farnesoic acid multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [Flurbiprofen results in decreased activity of AKR1C3 protein] which results in increased chemical synthesis of more ... CTD PMID:21187079 Akr1c3 Rat farnesol increases chemical synthesis ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased chemical synthesis of Farnesol CTD PMID:21187079 Akr1c3 Rat farnesol multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [Flurbiprofen results in decreased activity of AKR1C3 protein] which results in increased metabolism of Farnesol; more ... CTD PMID:21187079 Akr1c3 Rat fenamic acid decreases activity ISO AKR1C3 (Homo sapiens) 6480464 fenamic acid analog results in decreased activity of AKR1C3 protein CTD PMID:19010312 Akr1c3 Rat flufenamic acid affects binding ISO AKR1C3 (Homo sapiens) 6480464 Flufenamic Acid binds to AKR1C3 protein CTD PMID:14996743 Akr1c3 Rat flufenamic acid multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 Flufenamic Acid inhibits the reaction [AKR1C3 protein affects the susceptibility to oxaliplatin]; Flufenamic Acid inhibits more ... CTD PMID:14672942|PMID:23933386 Akr1c3 Rat flufenamic acid decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Flufenamic Acid results in decreased activity of AKR1C3 protein CTD PMID:12604236 Akr1c3 Rat flunitrazepam decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Flunitrazepam results in decreased activity of AKR1C3 protein CTD PMID:11995921 Akr1c3 Rat flurbiprofen multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [Flurbiprofen results in decreased activity of AKR1C3 protein] which results in increased chemical synthesis of more ... CTD PMID:21187079 Akr1c3 Rat flurbiprofen decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Flurbiprofen results in decreased activity of AKR1C3 protein CTD PMID:19010312|PMID:21187079 Akr1c3 Rat folic acid multiple interactions ISO Akr1c18 (Mus musculus) 6480464 [Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in increased expression more ... CTD PMID:20938992|PMID:29127188 Akr1c3 Rat formaldehyde decreases expression ISO AKR1C3 (Homo sapiens) 6480464 Formaldehyde results in decreased expression of AKR1C3 mRNA CTD PMID:23649840 Akr1c3 Rat formaldehyde increases expression ISO AKR1C3 (Homo sapiens) 6480464 Formaldehyde results in increased expression of AKR1C3 mRNA CTD PMID:28937961 Akr1c3 Rat Frangulin A decreases activity ISO AKR1C3 (Homo sapiens) 6480464 frangulin A results in decreased activity of AKR1C3 protein CTD PMID:35065925 Akr1c3 Rat Frangulin B decreases activity ISO AKR1C3 (Homo sapiens) 6480464 frangulin B results in decreased activity of AKR1C3 protein CTD PMID:35065925 Akr1c3 Rat fructose multiple interactions ISO Akr1c18 (Mus musculus) 6480464 [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] more ... CTD PMID:37567420 Akr1c3 Rat furan increases expression ISO Akr1c18 (Mus musculus) 6480464 furan results in increased expression of AKR1C18 mRNA CTD PMID:24183702|PMID:37517673 Akr1c3 Rat geranylgeraniol increases chemical synthesis ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased chemical synthesis of geranylgeraniol CTD PMID:21187079 Akr1c3 Rat gliclazide decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Gliclazide results in decreased activity of AKR1C3 protein CTD PMID:26362498 Akr1c3 Rat glimepiride decreases activity ISO AKR1C3 (Homo sapiens) 6480464 glimepiride results in decreased activity of AKR1C3 protein CTD PMID:26362498 Akr1c3 Rat glipizide decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Glipizide results in decreased activity of AKR1C3 protein CTD PMID:26362498 Akr1c3 Rat glucose multiple interactions ISO Akr1c18 (Mus musculus) 6480464 [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] more ... CTD PMID:37567420 Akr1c3 Rat glyburide decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Glyburide results in decreased activity of AKR1C3 protein CTD PMID:26362498 Akr1c3 Rat glycidyl methacrylate decreases expression ISO AKR1C3 (Homo sapiens) 6480464 glycidyl methacrylate results in decreased expression of AKR1C3 protein CTD PMID:36641056 Akr1c3 Rat glycyrrhetinate affects activity ISO AKR1C3 (Homo sapiens) 6480464 18alpha-glycyrrhetinic acid affects the activity of AKR1C3 protein CTD PMID:11165023 Akr1c3 Rat glycyrrhetinate decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Glycyrrhetinic Acid results in decreased activity of AKR1C3 protein CTD PMID:12604236 Akr1c3 Rat glycyrrhetinic acid affects activity ISO AKR1C3 (Homo sapiens) 6480464 18alpha-glycyrrhetinic acid affects the activity of AKR1C3 protein CTD PMID:11165023 Akr1c3 Rat glycyrrhetinic acid decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Glycyrrhetinic Acid results in decreased activity of AKR1C3 protein CTD PMID:12604236 Akr1c3 Rat glyphosate decreases expression ISO Akr1c18 (Mus musculus) 6480464 Glyphosate results in decreased expression of AKR1C18 protein CTD PMID:37208198 Akr1c3 Rat gold atom increases expression ISO AKR1C3 (Homo sapiens) 6480464 Gold results in increased expression of AKR1C3 mRNA CTD PMID:29705079 Akr1c3 Rat gold(0) increases expression ISO AKR1C3 (Homo sapiens) 6480464 Gold results in increased expression of AKR1C3 mRNA CTD PMID:29705079 Akr1c3 Rat GSK-J4 decreases expression ISO AKR1C3 (Homo sapiens) 6480464 GSK-J4 results in decreased expression of AKR1C3 mRNA CTD PMID:29301935 Akr1c3 Rat hexane increases expression ISO AKR1C3 (Homo sapiens) 6480464 n-hexane results in increased expression of AKR1C3 mRNA CTD PMID:20566472 Akr1c3 Rat hexestrol decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Hexestrol results in decreased activity of AKR1C3 protein CTD PMID:12604236 Akr1c3 Rat hydrogen peroxide multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 7-hydroxycoumarin inhibits the reaction [AKR1C3 mutant form results in increased susceptibility to Hydrogen Peroxide]; [AKR1C3 more ... CTD PMID:21910479|PMID:22964423 Akr1c3 Rat hydrogen peroxide increases expression ISO AKR1C3 (Homo sapiens) 6480464 Hydrogen Peroxide results in increased expression of AKR1C3 protein CTD PMID:22964423 Akr1c3 Rat hydrogen peroxide increases response to substance ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 mutant form results in increased susceptibility to Hydrogen Peroxide CTD PMID:22964423 Akr1c3 Rat ibuprofen decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Ibuprofen results in decreased activity of AKR1C3 protein CTD PMID:19010312 Akr1c3 Rat idarubicin multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in increased metabolism of Idarubicin] which results in increased abundance of idarubicinol; more ... CTD PMID:38175295 Akr1c3 Rat idarubicin increases metabolic processing ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased metabolism of Idarubicin CTD PMID:38175295 Akr1c3 Rat Idarubicinol multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in increased metabolism of Idarubicin] which results in increased abundance of idarubicinol; more ... CTD PMID:38175295 Akr1c3 Rat indometacin multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression more ... CTD PMID:17950253|PMID:28628672 Akr1c3 Rat indometacin decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Indomethacin analog results in decreased activity of AKR1C3 protein; Indomethacin results in decreased activity of more ... CTD PMID:12604236|PMID:17950253|PMID:19010312 Akr1c3 Rat indometacin affects binding ISO AKR1C3 (Homo sapiens) 6480464 Indomethacin binds to AKR1C3 protein CTD PMID:14996743 Akr1c3 Rat inulin multiple interactions ISO Akr1c18 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of AKR1C18 mRNA CTD PMID:36331819 Akr1c3 Rat isoeugenol increases expression ISO AKR1C3 (Homo sapiens) 6480464 isoeugenol results in increased expression of AKR1C3 mRNA CTD PMID:20566472 Akr1c3 Rat isoniazide increases expression ISO AKR1C3 (Homo sapiens) 6480464 Isoniazid results in increased expression of AKR1C3 protein CTD PMID:40015660 Akr1c3 Rat Isoxanthohumol decreases activity ISO AKR1C3 (Homo sapiens) 6480464 isoxanthohumol results in decreased activity of AKR1C3 protein CTD PMID:35065925 Akr1c3 Rat ivermectin decreases expression ISO AKR1C3 (Homo sapiens) 6480464 Ivermectin results in decreased expression of AKR1C3 protein CTD PMID:32959892 Akr1c3 Rat L-methionine multiple interactions ISO Akr1c18 (Mus musculus) 6480464 [Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in increased expression more ... CTD PMID:20938992|PMID:29127188 Akr1c3 Rat lead diacetate increases expression ISO AKR1C3 (Homo sapiens) 6480464 lead acetate results in increased expression of AKR1C3 mRNA CTD PMID:38568856 Akr1c3 Rat levonorgestrel decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Levonorgestrel results in decreased activity of AKR1C3 protein CTD PMID:21182831 Akr1c3 Rat lithocholic acid decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Lithocholic Acid results in decreased activity of AKR1C3 protein CTD PMID:12604236|PMID:21851338 Akr1c3 Rat LY294002 multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cadmium acetate results in increased expression of AKR1C3 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits more ... CTD PMID:18826220|PMID:21787718 Akr1c3 Rat meclofenamic acid decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Meclofenamic Acid results in decreased activity of AKR1C3 protein CTD PMID:19010312|PMID:26362498|PMID:27163852 Akr1c3 Rat Medazepam decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Medazepam results in decreased activity of AKR1C3 protein CTD PMID:11995921|PMID:12604236 Akr1c3 Rat medroxyprogesterone acetate multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [Medroxyprogesterone Acetate inhibits the reaction [[AKR1C3 protein results in increased metabolism of Prostaglandin D2] which more ... CTD PMID:19997560|PMID:23261716 Akr1c3 Rat medroxyprogesterone acetate decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Medroxyprogesterone Acetate results in decreased activity of AKR1C3 protein CTD PMID:12604236|PMID:19997560|PMID:21182831|PMID:23261716 Akr1c3 Rat mefenamic acid decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Mefenamic Acid analog results in decreased activity of AKR1C3 protein CTD PMID:19010312 Akr1c3 Rat mercury dibromide increases expression ISO AKR1C3 (Homo sapiens) 6480464 mercuric bromide results in increased expression of AKR1C3 mRNA CTD PMID:26272509 Akr1c3 Rat mercury dibromide multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Akr1c3 Rat mercury dichloride increases expression ISO AKR1C3 (Homo sapiens) 6480464 Mercuric Chloride results in increased expression of AKR1C3 mRNA CTD PMID:38568856 Akr1c3 Rat methapyrilene increases methylation ISO AKR1C3 (Homo sapiens) 6480464 Methapyrilene results in increased methylation of AKR1C3 intron CTD PMID:30157460 Akr1c3 Rat methyl salicylate increases expression ISO AKR1C3 (Homo sapiens) 6480464 methyl salicylate results in increased expression of AKR1C3 mRNA CTD PMID:20566472 Akr1c3 Rat methylarsonic acid increases expression ISO AKR1C3 (Homo sapiens) 6480464 monomethylarsonic acid results in increased expression of AKR1C3 mRNA CTD PMID:38630284 Akr1c3 Rat methylglyoxal increases expression ISO AKR1C3 (Homo sapiens) 6480464 Pyruvaldehyde results in increased expression of AKR1C3 mRNA CTD PMID:25451587 Akr1c3 Rat methylmercury chloride increases expression ISO Akr1c18 (Mus musculus) 6480464 methylmercuric chloride results in increased expression of AKR1C18 mRNA CTD PMID:20061341 Akr1c3 Rat methylmercury chloride increases expression ISO AKR1C3 (Homo sapiens) 6480464 methylmercuric chloride results in increased expression of AKR1C3 mRNA CTD PMID:28001369 Akr1c3 Rat methylparaben decreases expression ISO AKR1C3 (Homo sapiens) 6480464 methylparaben results in decreased expression of AKR1C3 mRNA CTD PMID:38568856 Akr1c3 Rat midostaurin decreases activity ISO AKR1C3 (Homo sapiens) 6480464 midostaurin results in decreased activity of AKR1C3 protein CTD PMID:33025066 Akr1c3 Rat midostaurin multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 midostaurin inhibits the reaction [AKR1C3 protein results in decreased susceptibility to Daunorubicin]; midostaurin inhibits the more ... CTD PMID:33025066 Akr1c3 Rat N-acetyl-L-cysteine multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [cadmium acetate results in increased expression of AKR1C3 protein]; Acetylcysteine inhibits more ... CTD PMID:18829485|PMID:21787718 Akr1c3 Rat N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases expression ISO AKR1C3 (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of AKR1C3 mRNA CTD PMID:21215737|PMID:23165153 Akr1c3 Rat N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [tolfenamic acid inhibits the reaction [AKR1C3 protein results in decreased more ... CTD PMID:23165153 Akr1c3 Rat N-nitrosodiethylamine increases expression ISO Akr1c18 (Mus musculus) 6480464 Diethylnitrosamine results in increased expression of AKR1C18 mRNA CTD PMID:24535843 Akr1c3 Rat N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of AKR1C18 mRNA CTD PMID:18164116 Akr1c3 Rat N-nitrosomorpholine increases expression EXP 6480464 N-nitrosomorpholine results in increased expression of AKR1C18 protein CTD PMID:19716841 Akr1c3 Rat NAD zwitterion multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein co-treated with NAD] results in increased oxidation of acenaphthene-1-ol; dichloro(4-cymene)ruthenium(II) analog inhibits the more ... CTD PMID:25446855 Akr1c3 Rat NAD(+) multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein co-treated with NAD] results in increased oxidation of acenaphthene-1-ol; dichloro(4-cymene)ruthenium(II) analog inhibits the more ... CTD PMID:25446855 Akr1c3 Rat NADP zwitterion multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein co-treated with NADP] results in increased oxidation of and affects the activity of more ... CTD PMID:14672942|PMID:21910479|PMID:23261716 Akr1c3 Rat NADP(+) multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein co-treated with NADP] results in increased oxidation of and affects the activity of more ... CTD PMID:14672942|PMID:21910479|PMID:23261716 Akr1c3 Rat naphthalenes multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased reduction of and affects the activity of Naphthalenes CTD PMID:21910479 Akr1c3 Rat naproxen decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Naproxen results in decreased activity of AKR1C3 protein CTD PMID:19010312 Akr1c3 Rat nickel atom decreases expression ISO AKR1C3 (Homo sapiens) 6480464 Nickel results in decreased expression of AKR1C3 mRNA CTD PMID:23195993 Akr1c3 Rat nickel sulfate increases expression ISO AKR1C3 (Homo sapiens) 6480464 nickel sulfate results in increased expression of AKR1C3 mRNA CTD PMID:20566472 Akr1c3 Rat nitrazepam decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Nitrazepam results in decreased activity of AKR1C3 protein CTD PMID:11995921 Akr1c3 Rat norethisterone decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Norethindrone results in decreased activity of AKR1C3 protein CTD PMID:21182831 Akr1c3 Rat Nutlin-3 multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [Dactinomycin co-treated with nutlin 3] results in increased secretion of AKR1C3 protein CTD PMID:38460933 Akr1c3 Rat ochratoxin A decreases expression ISO AKR1C3 (Homo sapiens) 6480464 ochratoxin A results in decreased expression of AKR1C3 mRNA CTD PMID:19287073|PMID:32905824 Akr1c3 Rat octyl gallate decreases activity ISO AKR1C3 (Homo sapiens) 6480464 octyl gallate results in decreased activity of AKR1C3 protein CTD PMID:27163852 Akr1c3 Rat oxaliplatin multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 alpha-methylcinnamic acid inhibits the reaction [AKR1C3 protein affects the susceptibility to oxaliplatin]; Flufenamic Acid inhibits more ... CTD PMID:23933386 Akr1c3 Rat oxaliplatin affects response to substance ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein affects the susceptibility to oxaliplatin CTD PMID:23933386 Akr1c3 Rat oxcarbazepine increases reduction ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased reduction of oxcarbazepine CTD PMID:25063510 Akr1c3 Rat oxidopamine increases expression ISO AKR1C3 (Homo sapiens) 6480464 Oxidopamine results in increased expression of AKR1C3 mRNA; Oxidopamine results in increased expression of AKR1C3 more ... CTD PMID:33486071 Akr1c3 Rat oxycodone decreases expression EXP 6480464 Oxycodone results in decreased expression of AKR1C3 mRNA CTD PMID:23439660 Akr1c3 Rat ozone multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ... CTD PMID:32699268 Akr1c3 Rat p-chloromercuribenzoic acid increases expression ISO AKR1C3 (Homo sapiens) 6480464 p-Chloromercuribenzoic Acid results in increased expression of AKR1C3 mRNA CTD PMID:26272509 Akr1c3 Rat p-chloromercuribenzoic acid multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Akr1c3 Rat Panaxytriol increases activity ISO AKR1C3 (Homo sapiens) 6480464 panaxytriol results in increased activity of AKR1C3 protein CTD PMID:18826220 Akr1c3 Rat Panaxytriol multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [panaxytriol results in increased activity of AKR1C3 protein]; Ro 31-8220 inhibits more ... CTD PMID:18826220 Akr1c3 Rat paracetamol decreases expression ISO AKR1C3 (Homo sapiens) 6480464 Acetaminophen results in decreased expression of AKR1C3 mRNA CTD PMID:21420995 Akr1c3 Rat paracetamol multiple interactions ISO Akr1c18 (Mus musculus) 6480464 PANX1 gene mutant form inhibits the reaction [Acetaminophen results in increased expression of AKR1C18 mRNA] CTD PMID:29246445 Akr1c3 Rat paracetamol increases expression ISO Akr1c18 (Mus musculus) 6480464 Acetaminophen results in increased expression of AKR1C18 mRNA CTD PMID:29246445 Akr1c3 Rat paracetamol affects expression ISO Akr1c18 (Mus musculus) 6480464 Acetaminophen affects the expression of AKR1C18 mRNA CTD PMID:17562736 Akr1c3 Rat paraquat multiple interactions ISO Akr1c18 (Mus musculus) 6480464 [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of AKR1C3 mRNA CTD PMID:28012437 Akr1c3 Rat perfluorohexanesulfonic acid increases expression ISO Akr1c18 (Mus musculus) 6480464 perfluorohexanesulfonic acid results in increased expression of AKR1C18 mRNA CTD PMID:37315490|PMID:37995155 Akr1c3 Rat perfluorooctane-1-sulfonic acid affects expression ISO Akr1c18 (Mus musculus) 6480464 perfluorooctane sulfonic acid affects the expression of AKR1C18 mRNA; perfluorooctane sulfonic acid affects the expression more ... CTD PMID:19429403 Akr1c3 Rat perfluorooctane-1-sulfonic acid multiple interactions ISO Akr1c18 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of AKR1C18 mRNA CTD PMID:36331819 Akr1c3 Rat perfluorooctanoic acid affects expression ISO Akr1c18 (Mus musculus) 6480464 perfluorooctanoic acid affects the expression of AKR1C18 mRNA; perfluorooctanoic acid affects the expression of AKR1C3 more ... CTD PMID:19429403 Akr1c3 Rat perfluorooctanoic acid multiple interactions EXP 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of AKR1C3 mRNA CTD PMID:35163327 Akr1c3 Rat perfluorooctanoic acid decreases expression EXP 6480464 perfluorooctanoic acid results in decreased expression of AKR1C18 mRNA CTD PMID:16221955|PMID:19162173 Akr1c3 Rat perfluorooctanoic acid increases expression ISO Akr1c18 (Mus musculus) 6480464 perfluorooctanoic acid results in increased expression of AKR1C3 mRNA CTD PMID:17681415 Akr1c3 Rat phenethyl caffeate decreases activity ISO AKR1C3 (Homo sapiens) 6480464 caffeic acid phenethyl ester results in decreased activity of AKR1C3 protein CTD PMID:27163852 Akr1c3 Rat phenobarbital increases expression ISO AKR1C3 (Homo sapiens) 6480464 Phenobarbital results in increased expression of AKR1C3 protein CTD PMID:35881160 Akr1c3 Rat phenolphthalein multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 Phenolphthalein inhibits the reaction [AKR1C3 protein affects the susceptibility to oxaliplatin] CTD PMID:23933386 Akr1c3 Rat phenolphthalein decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Phenolphthalein results in decreased activity of AKR1C3 protein CTD PMID:12604236 Akr1c3 Rat phenylmercury acetate increases expression ISO AKR1C3 (Homo sapiens) 6480464 Phenylmercuric Acetate results in increased expression of AKR1C3 mRNA CTD PMID:26272509 Akr1c3 Rat phenylmercury acetate multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Akr1c3 Rat phthalaldehyde affects expression ISO Akr1c18 (Mus musculus) 6480464 o-Phthalaldehyde affects the expression of AKR1C18 mRNA CTD PMID:22302311 Akr1c3 Rat picoxystrobin increases expression ISO AKR1C3 (Homo sapiens) 6480464 picoxystrobin results in increased expression of AKR1C3 mRNA CTD PMID:33512557 Akr1c3 Rat pirinixic acid multiple interactions ISO Akr1c18 (Mus musculus) 6480464 PPARA protein promotes the reaction [pirinixic acid results in increased expression of AKR1C18 mRNA] CTD PMID:17950772|PMID:20032461 Akr1c3 Rat pirinixic acid increases expression ISO Akr1c18 (Mus musculus) 6480464 pirinixic acid results in increased expression of AKR1C18 mRNA CTD PMID:17950772|PMID:18301758|PMID:20032461|PMID:20813756|PMID:23811191 Akr1c3 Rat potassium chromate multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of AKR1C3 mRNA CTD PMID:22079256 Akr1c3 Rat potassium chromate decreases expression ISO AKR1C3 (Homo sapiens) 6480464 potassium chromate(VI) results in decreased expression of AKR1C3 mRNA CTD PMID:22079256 Akr1c3 Rat pravastatin decreases expression ISO Akr1c18 (Mus musculus) 6480464 Pravastatin results in decreased expression of AKR1C18 mRNA CTD PMID:27225895 Akr1c3 Rat pravastatin decreases expression EXP 6480464 Pravastatin results in decreased expression of AKR1C3 mRNA CTD PMID:27225895 Akr1c3 Rat progesterone multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in increased metabolism of Progesterone] which results in increased chemical synthesis of more ... CTD PMID:19010312|PMID:20036328 Akr1c3 Rat progesterone increases metabolic processing EXP 6480464 AKR1C18 protein results in increased metabolism of Progesterone CTD PMID:8172618 Akr1c3 Rat progesterone affects metabolic processing EXP 6480464 AKR1C18 protein affects the metabolism of Progesterone CTD PMID:15261307 Akr1c3 Rat progesterone increases metabolic processing ISO Akr1c18 (Mus musculus) 6480464 AKR1C18 protein results in increased metabolism of Progesterone CTD PMID:17122075 Akr1c3 Rat progesterone affects metabolic processing ISO Akr1c18 (Mus musculus) 6480464 AKR1C18 protein affects the metabolism of Progesterone CTD PMID:15471942 Akr1c3 Rat progesterone affects abundance ISO Akr1c18 (Mus musculus) 6480464 AKR1C18 protein affects the abundance of Progesterone CTD PMID:15471942 Akr1c3 Rat progesterone increases reduction ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased reduction of Progesterone CTD PMID:20036328|PMID:25463305 Akr1c3 Rat progesterone decreases expression ISO AKR1C3 (Homo sapiens) 6480464 Progesterone results in decreased expression of AKR1C3 mRNA CTD PMID:23183084 Akr1c3 Rat progesterone increases expression ISO AKR1C3 (Homo sapiens) 6480464 Progesterone results in increased expression of AKR1C3 mRNA CTD PMID:23183084 Akr1c3 Rat progesterone increases metabolic processing ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased metabolism of Progesterone CTD PMID:19010312 Akr1c3 Rat propan-2-ol increases expression ISO AKR1C3 (Homo sapiens) 6480464 2-Propanol results in increased expression of AKR1C3 mRNA CTD PMID:20566472 Akr1c3 Rat prostaglandin D2 increases metabolic processing ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased metabolism of Prostaglandin D2 CTD PMID:19010312 Akr1c3 Rat prostaglandin D2 increases reduction ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased reduction of Prostaglandin D2 CTD PMID:20036328 Akr1c3 Rat prostaglandin D2 decreases response to substance ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in decreased susceptibility to Prostaglandin D2 CTD PMID:20036328 Akr1c3 Rat prostaglandin D2 decreases metabolic processing ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in decreased metabolism of Prostaglandin D2 CTD PMID:20036328 Akr1c3 Rat prostaglandin D2 multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in decreased metabolism of Prostaglandin D2] which results in decreased chemical synthesis more ... CTD PMID:19997560|PMID:20036328 Akr1c3 Rat prostaglandin F2alpha multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in increased reduction of Prostaglandin D2] which results in increased chemical synthesis more ... CTD PMID:19997560|PMID:20036328 Akr1c3 Rat prostaglandin J2 multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in decreased metabolism of Prostaglandin D2] which results in decreased chemical synthesis more ... CTD PMID:20036328 Akr1c3 Rat quercetin decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Quercetin results in decreased activity of AKR1C3 protein CTD PMID:19007764 Akr1c3 Rat rac-lactic acid increases expression ISO AKR1C3 (Homo sapiens) 6480464 Lactic Acid results in increased expression of AKR1C3 mRNA CTD PMID:20566472 Akr1c3 Rat ranirestat multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 ranirestat inhibits the reaction [[AKR1C3 protein results in increased metabolism of Idarubicin] which results in more ... CTD PMID:38175295 Akr1c3 Rat resveratrol multiple interactions EXP 6480464 [resveratrol co-treated with Streptozocin] results in decreased expression of AKR1C3 mRNA CTD PMID:25905778 Akr1c3 Rat Ro 31-8220 multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 Ro 31-8220 inhibits the reaction [panaxytriol results in increased activity of AKR1C3 protein] CTD PMID:18826220 Akr1c3 Rat rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of AKR1C3 mRNA CTD PMID:28374803 Akr1c3 Rat salicylic acid decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Salicylic Acid results in decreased activity of AKR1C3 protein CTD PMID:19010312 Akr1c3 Rat SB 431542 multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Akr1c3 Rat silibinin decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Silybin results in decreased activity of AKR1C3 protein CTD PMID:19007764 Akr1c3 Rat silicon dioxide decreases expression ISO AKR1C3 (Homo sapiens) 6480464 Silicon Dioxide analog results in decreased expression of AKR1C3 mRNA CTD PMID:25895662 Akr1c3 Rat silicon dioxide decreases expression ISO Akr1c18 (Mus musculus) 6480464 Silicon Dioxide results in decreased expression of AKR1C18 mRNA CTD PMID:29341224 Akr1c3 Rat silicon dioxide increases expression ISO AKR1C3 (Homo sapiens) 6480464 Silicon Dioxide results in increased expression of AKR1C3 mRNA CTD PMID:25351596 Akr1c3 Rat silicon dioxide increases secretion ISO AKR1C3 (Homo sapiens) 6480464 Silicon Dioxide analog results in increased secretion of AKR1C3 protein CTD PMID:25895662 Akr1c3 Rat simvastatin decreases expression ISO AKR1C3 (Homo sapiens) 6480464 Simvastatin results in decreased expression of AKR1C3 mRNA CTD PMID:18192897 Akr1c3 Rat sodium arsenate multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of arsenic acid] which results in increased expression of more ... CTD PMID:32525701|PMID:38630284 Akr1c3 Rat sodium arsenite increases expression ISO AKR1C3 (Homo sapiens) 6480464 sodium arsenite results in increased expression of AKR1C3 mRNA; sodium arsenite results in increased expression more ... CTD PMID:12727804|PMID:19696165|PMID:20886546|PMID:22714537|PMID:23876855|PMID:28595984|PMID:28713220|PMID:34032870|PMID:38568856 Akr1c3 Rat sodium arsenite multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [sodium arsenite results in increased abundance of arsenite] which results in increased expression of AKR1C3 more ... CTD PMID:32076005|PMID:38630284 Akr1c3 Rat sodium arsenite multiple interactions ISO Akr1c18 (Mus musculus) 6480464 sodium arsenite promotes the reaction [Diethylstilbestrol results in increased expression of AKR1C3 mRNA] CTD PMID:19665456 Akr1c3 Rat sodium arsenite affects expression ISO Akr1c18 (Mus musculus) 6480464 sodium arsenite affects the expression of AKR1C18 mRNA CTD PMID:16507464 Akr1c3 Rat sodium arsenite decreases expression ISO Akr1c18 (Mus musculus) 6480464 sodium arsenite results in decreased expression of AKR1C18 mRNA CTD PMID:17350061 Akr1c3 Rat sodium dichromate decreases expression EXP 6480464 sodium bichromate results in decreased expression of AKR1C3 mRNA CTD PMID:25993096 Akr1c3 Rat sodium dodecyl sulfate increases expression ISO AKR1C3 (Homo sapiens) 6480464 Sodium Dodecyl Sulfate results in increased expression of AKR1C3 mRNA CTD PMID:20566472 Akr1c3 Rat sodium dodecyl sulfate decreases expression ISO AKR1C3 (Homo sapiens) 6480464 Sodium Dodecyl Sulfate results in decreased expression of AKR1C3 mRNA CTD PMID:31734321 Akr1c3 Rat sodium dodecyl sulfate decreases expression EXP 6480464 Sodium Dodecyl Sulfate results in decreased expression of AKR1C18 mRNA CTD PMID:12815608 Akr1c3 Rat streptozocin multiple interactions EXP 6480464 [resveratrol co-treated with Streptozocin] results in decreased expression of AKR1C3 mRNA CTD PMID:25905778 Akr1c3 Rat streptozocin multiple interactions ISO Akr1c18 (Mus musculus) 6480464 [Streptozocin co-treated with Dietary Fats] results in increased expression of AKR1C18 mRNA CTD PMID:29127188 Akr1c3 Rat sulforaphane increases expression ISO AKR1C3 (Homo sapiens) 6480464 sulforaphane results in increased expression of AKR1C3 mRNA; sulforaphane results in increased expression of AKR1C3 more ... CTD PMID:24383545|PMID:31746589 Akr1c3 Rat sulindac decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Sulindac results in decreased activity of AKR1C3 protein CTD PMID:19010312 Akr1c3 Rat sulpiride decreases expression EXP 6480464 Sulpiride results in decreased expression of AKR1C3 mRNA CTD PMID:21427058 Akr1c3 Rat superoxide multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in increased reduction of 9,10-phenanthrenequinone] which results in increased abundance of Superoxides; more ... CTD PMID:19442656|PMID:21910479 Akr1c3 Rat testosterone increases abundance ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 promoter SNP results in increased abundance of Testosterone CTD PMID:16263811 Akr1c3 Rat testosterone multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in increased metabolism of Androstenedione] which results in increased chemical synthesis of more ... CTD PMID:19010312|PMID:20036328 Akr1c3 Rat testosterone enanthate affects expression ISO AKR1C3 (Homo sapiens) 6480464 testosterone enanthate affects the expression of AKR1C3 mRNA CTD PMID:17440010 Akr1c3 Rat tetrachloromethane increases expression ISO Akr1c18 (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of AKR1C18 mRNA CTD PMID:27339419 Akr1c3 Rat tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of AKR1C3 mRNA CTD PMID:31150632 Akr1c3 Rat tetraphene increases expression ISO AKR1C3 (Homo sapiens) 6480464 benz(a)anthracene results in increased expression of AKR1C3 mRNA CTD PMID:22236718 Akr1c3 Rat thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of AKR1C18 mRNA; Thioacetamide results in decreased expression of AKR1C3 more ... CTD PMID:23411599|PMID:34492290 Akr1c3 Rat titanium dioxide affects expression ISO Akr1c18 (Mus musculus) 6480464 titanium dioxide affects the expression of AKR1C18 mRNA CTD PMID:23557971 Akr1c3 Rat titanium dioxide multiple interactions ISO Akr1c18 (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of AKR1C18 more ... CTD PMID:29950665 Akr1c3 Rat titanium dioxide increases expression ISO Akr1c18 (Mus musculus) 6480464 titanium dioxide results in increased expression of AKR1C18 mRNA CTD PMID:23131501 Akr1c3 Rat tolcapone decreases expression EXP 6480464 tolcapone results in decreased expression of AKR1C3 mRNA CTD PMID:24136188 Akr1c3 Rat tolfenamic acid decreases activity ISO AKR1C3 (Homo sapiens) 6480464 tolfenamic acid results in decreased activity of AKR1C3 protein CTD PMID:21187079|PMID:23165153 Akr1c3 Rat tolfenamic acid multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [tolfenamic acid results in decreased activity of AKR1C3 protein] which results in increased chemical synthesis more ... CTD PMID:21187079|PMID:23165153 Akr1c3 Rat trans-isoeugenol increases expression ISO AKR1C3 (Homo sapiens) 6480464 isoeugenol results in increased expression of AKR1C3 mRNA CTD PMID:20566472 Akr1c3 Rat trichloroethene increases expression ISO Akr1c18 (Mus musculus) 6480464 Trichloroethylene results in increased expression of AKR1C18 mRNA CTD PMID:25549359 Akr1c3 Rat trichostatin A increases expression ISO AKR1C3 (Homo sapiens) 6480464 trichostatin A results in increased expression of AKR1C3 mRNA CTD PMID:24935251|PMID:26705709 Akr1c3 Rat triclosan decreases expression ISO AKR1C3 (Homo sapiens) 6480464 Triclosan results in decreased expression of AKR1C3 mRNA CTD PMID:30510588 Akr1c3 Rat trimellitic anhydride increases expression ISO Akr1c18 (Mus musculus) 6480464 trimellitic anhydride results in increased expression of AKR1C18 mRNA CTD PMID:19042947 Akr1c3 Rat trimellitic anhydride affects expression ISO Akr1c18 (Mus musculus) 6480464 trimellitic anhydride affects the expression of AKR1C18 mRNA CTD PMID:22302311 Akr1c3 Rat triphenyl phosphate affects expression ISO AKR1C3 (Homo sapiens) 6480464 triphenyl phosphate affects the expression of AKR1C3 mRNA CTD PMID:37042841 Akr1c3 Rat troglitazone increases expression ISO Akr1c18 (Mus musculus) 6480464 troglitazone results in increased expression of AKR1C3 mRNA CTD PMID:28973697 Akr1c3 Rat umbelliferone increases expression ISO AKR1C3 (Homo sapiens) 6480464 7-hydroxycoumarin results in increased expression of AKR1C3 mRNA; 7-hydroxycoumarin results in increased expression of AKR1C3 more ... CTD PMID:22964423|PMID:28263721 Akr1c3 Rat umbelliferone multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 7-hydroxycoumarin inhibits the reaction [AKR1C3 mutant form results in increased susceptibility to 4-hydroxy-2-nonenal]; 7-hydroxycoumarin inhibits more ... CTD PMID:22964423 Akr1c3 Rat uranium atom affects expression ISO AKR1C3 (Homo sapiens) 6480464 Uranium affects the expression of AKR1C3 mRNA CTD PMID:15672453 Akr1c3 Rat urethane decreases expression ISO AKR1C3 (Homo sapiens) 6480464 Urethane results in decreased expression of AKR1C3 mRNA CTD PMID:28818685 Akr1c3 Rat ursodeoxycholic acid decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Ursodeoxycholic Acid results in decreased activity of AKR1C3 protein CTD PMID:12604236 Akr1c3 Rat valproic acid decreases methylation ISO AKR1C3 (Homo sapiens) 6480464 Valproic Acid results in decreased methylation of AKR1C3 gene CTD PMID:29154799 Akr1c3 Rat valproic acid multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Akr1c3 Rat valproic acid increases expression ISO AKR1C3 (Homo sapiens) 6480464 Valproic Acid results in increased expression of AKR1C3 mRNA CTD PMID:23179753|PMID:24383497|PMID:24935251|PMID:25192806|PMID:26272509|PMID:26705709|PMID:28001369 Akr1c3 Rat valproic acid affects expression ISO Akr1c18 (Mus musculus) 6480464 Valproic Acid affects the expression of AKR1C18 mRNA CTD PMID:17292431 Akr1c3 Rat valproic acid affects expression ISO AKR1C3 (Homo sapiens) 6480464 Valproic Acid affects the expression of AKR1C3 mRNA CTD PMID:25979313 Akr1c3 Rat vorinostat increases expression ISO AKR1C3 (Homo sapiens) 6480464 vorinostat results in increased expression of AKR1C3 mRNA CTD PMID:18769122 Akr1c3 Rat vorinostat decreases expression ISO AKR1C3 (Homo sapiens) 6480464 vorinostat results in decreased expression of AKR1C3 mRNA CTD PMID:18769122 Akr1c3 Rat zaragozic acid A increases expression EXP 6480464 squalestatin 1 results in increased expression of AKR1C3 mRNA CTD PMID:27225895 Akr1c3 Rat zaragozic acid A affects expression ISO Akr1c18 (Mus musculus) 6480464 squalestatin 1 affects the expression of AKR1C18 mRNA CTD PMID:27225895 Akr1c3 Rat zinc atom decreases expression ISO AKR1C3 (Homo sapiens) 6480464 Zinc deficiency results in decreased expression of AKR1C3 mRNA CTD PMID:22171008 Akr1c3 Rat zinc(0) decreases expression ISO AKR1C3 (Homo sapiens) 6480464 Zinc deficiency results in decreased expression of AKR1C3 mRNA CTD PMID:22171008 Akr1c3 Rat zomepirac decreases activity ISO AKR1C3 (Homo sapiens) 6480464 zomepirac results in decreased activity of AKR1C3 protein CTD PMID:19010312