Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Akr1c2 (aldo-keto reductase family 1, member C2) Rattus norvegicus
Analyze
Symbol: Akr1c2
Name: aldo-keto reductase family 1, member C2
Description: Predicted to have NADP binding activity; lithocholic acid binding activity; and oxidoreductase activity. Predicted to be involved in several processes, including cellular response to hormone stimulus; glycoside metabolic process; and positive regulation of protein kinase B signaling. Predicted to localize to cytosol. Human ortholog(s) of this gene implicated in 46,XY sex reversal 8. Orthologous to human AKR1C2 (aldo-keto reductase family 1 member C2); INTERACTS WITH (+)-schisandrin B; acrylamide; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 17-alpha-HSD; 17-alpha-hydroxysteroid dehydrogenase; 3(17)alpha-hydroxysteroid dehydrogenase; 3(or 17)-alpha-hydroxysteroid dehydrogenase; 3-alpha-hydroxysteroid dehydrogenase; Akr1c21; aldo-keto reductase family 1 member C21; aldo-keto reductase family 1, member C21; LOC291283; RAKg
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01769,388,337 - 69,435,160 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1769,388,335 - 69,404,341 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01771,102,094 - 71,148,911 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41777,034,737 - 77,081,406 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11777,045,579 - 77,092,239 (-)NCBI
Celera1765,292,033 - 65,339,839 (-)NCBICelera
Cytogenetic Map17q12.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Akr1c2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1311841
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.