Atp5f1c (ATP synthase F1 subunit gamma) - Rat Genome Database

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Gene: Atp5f1c (ATP synthase F1 subunit gamma) Rattus norvegicus
Analyze
Symbol: Atp5f1c
Name: ATP synthase F1 subunit gamma
RGD ID: 620011
Description: Contributes to ATP hydrolysis activity. Involved in cellular response to nitric oxide. Located in mitochondrial inner membrane. Part of mitochondrial proton-transporting ATP synthase complex and proton-transporting ATP synthase complex, catalytic core F(1). Biomarker of schizophrenia. Orthologous to human ATP5F1C (ATP synthase F1 subunit gamma); PARTICIPATES IN electron transport chain pathway; Alzheimer's disease pathway; Huntington's disease pathway; INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ATP synthase subunit gamma, mitochondrial; ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1; Atp5c1; F-ATPase gamma subunit
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81773,333,584 - 73,355,872 (+)NCBIGRCr8
mRatBN7.21768,423,927 - 68,446,169 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1768,423,909 - 68,608,367 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1771,906,434 - 71,928,628 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01775,735,168 - 75,757,362 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01769,778,221 - 69,800,417 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01772,209,321 - 72,231,562 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1772,209,373 - 72,394,271 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01773,895,019 - 73,917,300 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41779,738,999 - 79,761,176 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11779,749,831 - 79,772,008 (+)NCBI
Celera1767,910,474 - 67,932,651 (+)NCBICelera
Cytogenetic Map17q12.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
4,4'-sulfonyldiphenol  (ISO)
5-methyl-4-oxido-2-pyrazin-4-iumcarboxylic acid  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
antimycin A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenic trichloride  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
azoxystrobin  (ISO)
benzatropine  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
chloropicrin  (ISO)
clofibrate  (EXP,ISO)
clotrimazole  (EXP)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
deoxynivalenol  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP,ISO)
dicrotophos  (ISO)
doxorubicin  (ISO)
fenpyroximate  (ISO)
flutamide  (EXP,ISO)
FR900359  (ISO)
gentamycin  (EXP)
isotretinoin  (ISO)
ivermectin  (ISO)
lamivudine  (ISO)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
manganese(II) chloride  (EXP)
methidathion  (ISO)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
mitoxantrone  (ISO)
oxybenzone  (EXP)
p-toluidine  (EXP)
paracetamol  (EXP,ISO)
parathion  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenylpropanolamine  (ISO)
phlorizin  (ISO)
picoxystrobin  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sunitinib  (ISO)
tetrachloromethane  (EXP)
thapsigargin  (EXP)
thiram  (ISO)
tolcapone  (EXP)
toluene  (EXP)
Tributyltin oxide  (EXP)
triphenyl phosphate  (ISO)
triptonide  (ISO)
tungsten  (ISO)
valproic acid  (EXP,ISO)
vincristine  (ISO)
vitamin E  (ISO)
zidovudine  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Chromosomal localization of genes required for the terminal steps of oxidative metabolism: alpha and gamma subunits of ATP synthase and the phosphate carrier. Jabs EW, etal., Hum Genet 1994 May;93(5):600-2.
4. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
5. Mitochondrial F(0)F(1) ATP synthase. Subunit regions on the F1 motor shielded by F(0), Functional significance, and evidence for an involvement of the unique F(0) subunit F(6). Ko YH, etal., J Biol Chem. 2000 Oct 20;275(42):32931-9.
6. Identification of two proteins associated with mammalian ATP synthase. Meyer B, etal., Mol Cell Proteomics. 2007 Oct;6(10):1690-9. Epub 2007 Jun 17.
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
9. Mitochondrial ATP synthase: dramatic Mg2+-induced alterations in the structure and function of the F1-ATPase moiety. Pedersen PL, etal., Biochemistry. 1987 Dec 29;26(26):8631-7.
10. Thyroid hormone-related regulation of gene expression in human fatty liver. Pihlajamäki J, etal., J Clin Endocrinol Metab. 2009 Sep;94(9):3521-9. doi: 10.1210/jc.2009-0212. Epub 2009 Jun 23.
11. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
12. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
13. GOA pipeline RGD automated data pipeline
14. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
15. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
16. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
17. Transcriptomic analysis reveals oxidative phosphorylation activation in an adolescent social isolation rat model. Sun L, etal., Brain Res Bull. 2018 Aug 22;142:304-312. doi: 10.1016/j.brainresbull.2018.08.013.
18. Impact of exposure to low concentrations of nitric oxide on protein profile in murine and human pancreatic islet cells. Tapia-Limonchi R, etal., Islets. 2014;6(5-6):e995997. doi: 10.1080/19382014.2014.995997.
Additional References at PubMed
PMID:9736690   PMID:12110673   PMID:12865426   PMID:14651853   PMID:17634366   PMID:18614015   PMID:19946888   PMID:22658674   PMID:23376485   PMID:24625528   PMID:25931508   PMID:29476059  
PMID:31904090   PMID:32357304   PMID:35659652  


Genomics

Comparative Map Data
Atp5f1c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81773,333,584 - 73,355,872 (+)NCBIGRCr8
mRatBN7.21768,423,927 - 68,446,169 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1768,423,909 - 68,608,367 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1771,906,434 - 71,928,628 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01775,735,168 - 75,757,362 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01769,778,221 - 69,800,417 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01772,209,321 - 72,231,562 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1772,209,373 - 72,394,271 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01773,895,019 - 73,917,300 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41779,738,999 - 79,761,176 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11779,749,831 - 79,772,008 (+)NCBI
Celera1767,910,474 - 67,932,651 (+)NCBICelera
Cytogenetic Map17q12.3NCBI
ATP5F1C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38107,788,177 - 7,807,801 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl107,788,147 - 7,807,815 (+)EnsemblGRCh38hg38GRCh38
GRCh37107,830,140 - 7,849,764 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36107,870,099 - 7,889,770 (+)NCBINCBI36Build 36hg18NCBI36
Build 34107,870,098 - 7,889,766NCBI
Celera107,755,913 - 7,775,585 (+)NCBICelera
Cytogenetic Map10p14NCBI
HuRef107,748,461 - 7,768,132 (+)NCBIHuRef
CHM1_1107,829,833 - 7,849,495 (+)NCBICHM1_1
T2T-CHM13v2.0107,788,947 - 7,808,583 (+)NCBIT2T-CHM13v2.0
Atp5f1c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39210,060,841 - 10,085,321 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl210,060,827 - 10,085,321 (-)EnsemblGRCm39 Ensembl
GRCm38210,056,030 - 10,080,510 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl210,056,016 - 10,080,510 (-)EnsemblGRCm38mm10GRCm38
MGSCv3729,977,657 - 10,002,137 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3629,973,887 - 9,998,282 (-)NCBIMGSCv36mm8
CeleraX56,411,914 - 56,412,248 (+)NCBICelera
Celera29,998,573 - 10,019,583 (-)NCBICelera
Cytogenetic Map2A1NCBI
cM Map26.86NCBI
Atp5f1c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542124,234,413 - 24,253,640 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542124,234,473 - 24,253,640 (+)NCBIChiLan1.0ChiLan1.0
ATP5F1C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2820,339,509 - 20,359,161 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11020,344,836 - 20,364,488 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0107,820,874 - 7,840,581 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1107,801,433 - 7,821,097 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl107,801,438 - 7,821,088 (+)Ensemblpanpan1.1panPan2
ATP5F1C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1228,306,857 - 28,325,149 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl228,306,857 - 28,325,116 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha225,347,713 - 25,366,002 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0228,688,476 - 28,706,739 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl228,688,483 - 28,706,764 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1225,794,880 - 25,813,165 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0226,636,833 - 26,655,096 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0227,354,962 - 27,373,216 (-)NCBIUU_Cfam_GSD_1.0
Atp5f1c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934430,850,402 - 30,865,882 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049364847,016,049 - 7,031,060 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ATP5F1C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1063,583,695 - 63,599,453 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11063,584,288 - 63,599,537 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ATP5F1C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.197,836,863 - 7,853,645 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl97,836,845 - 7,854,078 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605113,232,697 - 13,249,468 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Atp5f1c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247752,744,731 - 2,768,373 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247752,745,556 - 2,765,269 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Atp5f1c
38 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat
1354630Cm34Cardiac mass QTL 348.7heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)17429913069599340Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)17429913069599340Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
12903978Cm118Cardiac mass QTL 1180.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)172365318468653184Rat
12903979Cm119Cardiac mass QTL 1190.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172365318468653184Rat
12903980Cm120Cardiac mass QTL 1200.002heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)172365318468653184Rat
12903981Am17Aortic mass QTL 170.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)172365318468653184Rat
1559055Bp278Blood pressure QTL 2780.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318468653184Rat
12903982Kidm70Kidney mass QTL 700.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)172365318470974005Rat
1354619Bp242Blood pressure QTL 2426.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172459934069599340Rat
8552928Pigfal9Plasma insulin-like growth factor 1 level QTL 99blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)172840914773409147Rat
9590107Sffal7Serum free fatty acids level QTL 74.810.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)172840914773409147Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)173136839173951021Rat
724549Niddm56Non-insulin dependent diabetes mellitus QTL 560.03blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)173199078476990784Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173199078481292925Rat
1300148Bp192Blood pressure QTL 1923.47arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)173455084373951021Rat
724528Uae4Urinary albumin excretion QTL 44.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)173583708569599340Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)173747984782479847Rat
2317054Aia12Adjuvant induced arthritis QTL 124.24joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)173828150983281509Rat
2317060Aia26Adjuvant induced arthritis QTL 263.22joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)173828150983281509Rat
1598871Memor5Memory QTL 55.3exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)174054004180387013Rat
1358295Aocep1Aortic cell protein QTL 16.10.00000071thoracic aorta cellular protein amount (VT:0010598)aortic cell percentage174099000585990005Rat
1354635Bp245Blood pressure QTL 2456arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)174207316069599340Rat
1354635Bp245Blood pressure QTL 2456arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)174207316069599340Rat
7411575Bw140Body weight QTL 14030.20.001body mass (VT:0001259)body weight gain (CMO:0000420)174856093586533673Rat
8694181Bw151Body weight QTL 1514.360.001body mass (VT:0001259)body weight gain (CMO:0000420)174856093586533673Rat
2317038Ginf3Gastrointestinal inflammation QTL 32.890.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)174992015486533673Rat
2303580Gluco49Glucose level QTL 492blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)175004027186533673Rat
4889894Eae33Experimental allergic encephalomyelitis QTL 335.20.0001nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)175090909986022412Rat
1354588Bvd4Brain ventricular dilatation QTL 45.310.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)175349882882479847Rat
70210Cm15Cardiac mass QTL 156.5heart right ventricle mass (VT:0007033)heart right ventricle wet weight (CMO:0000072)175724672370156904Rat
1600398Edcs5Endometrial carcinoma susceptibility QTL 52.2uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)175724672370852846Rat
2302365Gluco40Glucose level QTL 404.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)175724684382046127Rat
7488963Bp369Blood pressure QTL 3690.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)175900564977910000Rat
2317045Aia11Adjuvant induced arthritis QTL 114.06joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)176078142686533673Rat
7411577Bw141Body weight QTL 1410.001body mass (VT:0001259)body weight gain (CMO:0000420)176261951686533673Rat
1300131Bp193Blood pressure QTL 1933.3arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)176364000973951021Rat
631502Cm26Cardiac mass QTL 263.71heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)176570358081153923Rat

Markers in Region
MARC_5003-5004:996690032:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21768,441,339 - 68,442,557 (+)MAPPERmRatBN7.2
Rnor_6.01772,226,733 - 72,227,950NCBIRnor6.0
Rnor_5.01773,912,437 - 73,913,654UniSTSRnor5.0
RGSC_v3.41779,756,357 - 79,757,574UniSTSRGSC3.4
Celera1767,927,832 - 67,929,049UniSTS
Cytogenetic Map17q12.3UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_053825 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006254229 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006254230 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006254231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC059158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212577 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212651 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212813 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213852 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213883 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214863 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214998 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215205 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215286 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215351 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215426 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216198 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216285 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216385 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216490 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216647 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216736 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219563 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219689 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220748 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224939 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234981 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L19927 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000025993   ⟹   ENSRNOP00000025993
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1772,240,802 - 72,394,271 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000041346   ⟹   ENSRNOP00000049879
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1768,423,909 - 68,473,374 (+)Ensembl
Rnor_6.0 Ensembl1772,218,769 - 72,258,890 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000064802   ⟹   ENSRNOP00000061946
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1768,423,935 - 68,446,163 (+)Ensembl
Rnor_6.0 Ensembl1772,209,373 - 72,231,551 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000090453   ⟹   ENSRNOP00000068697
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1768,455,461 - 68,608,367 (+)Ensembl
Rnor_6.0 Ensembl1772,240,852 - 72,393,448 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000098367   ⟹   ENSRNOP00000076528
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1768,431,430 - 68,446,169 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000104116   ⟹   ENSRNOP00000090262
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1768,423,917 - 68,446,202 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000116066   ⟹   ENSRNOP00000097532
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1768,423,909 - 68,443,995 (+)Ensembl
RefSeq Acc Id: NM_053825   ⟹   NP_446277
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81773,333,685 - 73,355,862 (+)NCBI
mRatBN7.21768,423,981 - 68,446,159 (+)NCBI
Rnor_6.01772,209,375 - 72,231,552 (+)NCBI
Rnor_5.01773,895,019 - 73,917,300 (+)NCBI
RGSC_v3.41779,738,999 - 79,761,176 (+)RGD
Celera1767,910,474 - 67,932,651 (+)RGD
Sequence:
RefSeq Acc Id: XM_006254229   ⟹   XP_006254291
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81773,333,593 - 73,355,872 (+)NCBI
mRatBN7.21768,423,927 - 68,446,169 (+)NCBI
Rnor_6.01772,209,321 - 72,231,562 (+)NCBI
Rnor_5.01773,895,019 - 73,917,300 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006254230   ⟹   XP_006254292
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81773,333,593 - 73,355,872 (+)NCBI
mRatBN7.21768,423,935 - 68,443,075 (+)NCBI
Rnor_6.01772,209,413 - 72,228,466 (+)NCBI
Rnor_5.01773,895,019 - 73,917,300 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006254231   ⟹   XP_006254293
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81773,341,151 - 73,355,872 (+)NCBI
mRatBN7.21768,431,525 - 68,446,169 (+)NCBI
Rnor_6.01772,216,880 - 72,231,556 (+)NCBI
Rnor_5.01773,895,019 - 73,917,300 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063276021   ⟹   XP_063132091
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81773,333,584 - 73,355,163 (+)NCBI
RefSeq Acc Id: NP_446277   ⟸   NM_053825
- UniProtKB: Q6PCU0 (UniProtKB/TrEMBL),   F7FFJ9 (UniProtKB/TrEMBL),   A0A8I5YBP6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006254291   ⟸   XM_006254229
- Peptide Label: isoform X2
- UniProtKB: A0A8J8YGG0 (UniProtKB/TrEMBL),   A0A8I5YBP6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006254292   ⟸   XM_006254230
- Peptide Label: isoform X3
- UniProtKB: A0A8J8YGG0 (UniProtKB/TrEMBL),   A0A8I5YBP6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006254293   ⟸   XM_006254231
- Peptide Label: isoform X4
- UniProtKB: P35435 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000049879   ⟸   ENSRNOT00000041346
RefSeq Acc Id: ENSRNOP00000068697   ⟸   ENSRNOT00000090453
RefSeq Acc Id: ENSRNOP00000061946   ⟸   ENSRNOT00000064802
RefSeq Acc Id: ENSRNOP00000025993   ⟸   ENSRNOT00000025993
RefSeq Acc Id: ENSRNOP00000090262   ⟸   ENSRNOT00000104116
RefSeq Acc Id: ENSRNOP00000076528   ⟸   ENSRNOT00000098367
RefSeq Acc Id: ENSRNOP00000097532   ⟸   ENSRNOT00000116066
RefSeq Acc Id: XP_063132091   ⟸   XM_063276021
- Peptide Label: isoform X1
- UniProtKB: A0A8I5YBP6 (UniProtKB/TrEMBL),   F7FFJ9 (UniProtKB/TrEMBL),   Q6PCU0 (UniProtKB/TrEMBL)
Protein Domains
Bromodomain associated

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P35435-F1-model_v2 AlphaFold P35435 1-273 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700561
Promoter ID:EPDNEW_R11084
Type:initiation region
Name:Atp5c1_1
Description:ATP synthase, H+ transporting, mitochondrial F1 complex, gammapolypeptide 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01772,209,375 - 72,209,435EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620011 AgrOrtholog
BioCyc Gene G2FUF-8755 BioCyc
BioCyc Pathway PWY-7980 [ATP biosynthesis] BioCyc
BioCyc Pathway Image PWY-7980 BioCyc
Ensembl Genes ENSRNOG00000019223 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000041346.5 UniProtKB/TrEMBL
  ENSRNOT00000064802.4 UniProtKB/TrEMBL
  ENSRNOT00000098367.1 UniProtKB/TrEMBL
  ENSRNOT00000104116.1 UniProtKB/TrEMBL
  ENSRNOT00000116066.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.20.10 UniProtKB/TrEMBL
  3.40.1380.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATP synthase, gamma subunit, helix hairpin domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:6920493 IMAGE-MGC_LOAD
InterPro ATP_synth_F1_ATPase_gsu UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATP_synth_F1_gsu UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATP_synth_F1_gsu_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BTP UniProtKB/TrEMBL
  Histone-fold UniProtKB/TrEMBL
KEGG Report rno:116550 UniProtKB/TrEMBL
MGC_CLONE MGC:72961 IMAGE-MGC_LOAD
NCBI Gene 116550 ENTREZGENE
PANTHER ATP SYNTHASE SUBUNIT GAMMA, MITOCHONDRIAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11693 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 3 UniProtKB/TrEMBL
  TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 3 UniProtKB/TrEMBL
Pfam ATP-synt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Bromo_TP UniProtKB/TrEMBL
PhenoGen Atp5f1c PhenoGen
PIRSF ATP_synthase_gamma UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS ATPASEGAMMA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ATPASE_GAMMA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000019223 RatGTEx
SMART BTP UniProtKB/TrEMBL
Superfamily-SCOP SSF52943 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5YBP6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GIR3_RAT UniProtKB/TrEMBL
  A0A8J8YGG0 ENTREZGENE, UniProtKB/TrEMBL
  ATPG_RAT UniProtKB/Swiss-Prot
  F7FFJ9 ENTREZGENE
  P35435 ENTREZGENE
  Q6PCU0 ENTREZGENE, UniProtKB/TrEMBL
  Q6QI09_RAT UniProtKB/TrEMBL
UniProt Secondary F7FFJ9 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-01-10 Atp5f1c  ATP synthase F1 subunit gamma  Atp5c1  ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Atp5c1  ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Atp5c1  ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1      Symbol and Name status set to provisional 70820 PROVISIONAL