Gene: Chrm3 (cholinergic receptor, muscarinic 3) Rattus norvegicus
Symbol: Chrm3
Name: cholinergic receptor, muscarinic 3
Description: Exhibits G protein-coupled acetylcholine receptor activity and acetylcholine binding activity; involved in G protein-coupled acetylcholine receptor signaling pathway and positive regulation of vascular smooth muscle contraction; localizes to the glutamatergic synapse, intrinsic component of plasma membrane, and neuron projection; orthologous to human CHRM3 (cholinergic receptor muscarinic 3); PARTICIPATES IN acetylcholine signaling pathway via muscarinic acetylcholine receptors engaging G alphaq protein family; cimetidine pharmacodynamics pathway; esomeprazole pharmacodynamics pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,4,6-trinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cholinergic receptor, muscarinic 3, cardiac; muscarinic acetylcholine receptor M3
Homo sapiens (human) : CHRM3 (cholinergic receptor muscarinic 3)  HGNC  Alliance
Mus musculus (house mouse) : Chrm3 (cholinergic receptor, muscarinic 3, cardiac)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Chrm3 (cholinergic receptor muscarinic 3)
Pan paniscus (bonobo/pygmy chimpanzee) : CHRM3 (cholinergic receptor muscarinic 3)
Canis lupus familiaris (dog) : CHRM3 (cholinergic receptor muscarinic 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Chrm3 (cholinergic receptor muscarinic 3)
Sus scrofa (pig) : CHRM3 (cholinergic receptor muscarinic 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01763,990,599 - 64,463,222 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01765,753,665 - 66,217,211 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41771,214,906 - 71,218,463 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11771,081,449 - 71,229,296 (+)NCBI
Celera1760,109,356 - 60,562,246 (-)NCBICelera
Cytogenetic Map17q12.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Chrm3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2343
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.