Gene: Akr1c1 (aldo-keto reductase family 1, member C1) Rattus norvegicus
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Symbol: Akr1c1
Name: aldo-keto reductase family 1, member C1
Description: ENCODES a protein that exhibits 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; testosterone 17-beta-dehydrogenase (NADP+) activity; androsterone dehydrogenase activity (ortholog); INVOLVED IN response to drug; response to estrogen; cellular response to jasmonic acid stimulus (ortholog); PARTICIPATES IN 11-beta-hydroxylase deficiency pathway; 17-alpha-hydroxylase deficiency pathway; 21-alpha-hydroxylase deficiency pathway; ASSOCIATED WITH 46 XY gonadal dysgenesis (ortholog); bipolar disorder (ortholog); Male Pseudohermaphroditism due to Deficiency of Testicular 17,20-Desmolase (ortholog); FOUND IN cytoplasm; nucleus; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 20-alpha (3-alpha)-hydroxysteroid dehydrogenase); Akr1c6; aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1, 20-alpha (3-alpha)-hydroxysteroid dehydrogenase); aldo-keto reductase family 1, member C6; Hsd17b5; LOC307092; MGC125057; type 5 17beta-hydroxysteroid dehydrogenase
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01769,441,253 - 69,460,334 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01771,155,010 - 71,174,079 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41777,084,306 - 77,112,994 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11777,095,138 - 77,123,818 (-)NCBI
Celera1765,342,356 - 65,364,506 (-)NCBICelera
Cytogenetic Map17q12.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Akr1c1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1306847
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2018-05-29
Status: ACTIVE