Ccny (cyclin Y) - Rat Genome Database

Name: Ccny
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Ccny (cyclin Y) Rattus norvegicus

Analyze

Symbol:

Ccny

Name:

cyclin Y

RGD ID:

1565969

Description:

Predicted to enable cyclin-dependent protein serine/threonine kinase activator activity. Predicted to be involved in several processes, including G2/M transition of mitotic cell cycle; positive regulation of autophagy; and positive regulation of cyclin-dependent protein serine/threonine kinase activity. Predicted to be located in nucleus. Predicted to be part of cytoplasmic cyclin-dependent protein kinase holoenzyme complex. Predicted to be active in plasma membrane. Orthologous to human CCNY (cyclin Y); INTERACTS WITH amphetamine; bisphenol A; cadmium dichloride.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

cyclin-Y; LOC361261; RGD1565969; similar to 5730405I09Rik protein

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CCNY (cyclin Y)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, Panther
Mus musculus (house mouse):	Ccny (cyclin Y)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ccny (cyclin Y)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CCNY (cyclin Y)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CCNY (cyclin Y)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ccny (cyclin Y)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CCNY (cyclin Y)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CCNY (cyclin Y)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ccny (cyclin Y)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	CCNY (cyclin Y)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Ccny (cyclin Y)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ccny (cyclin Y)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CycY	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	cyy-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	SIP3	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Saccharomyces cerevisiae (baker's yeast):	LAM1	Alliance	DIOPT (Ensembl Compara\|PANTHER)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	17	57,385,002 - 57,512,860 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	17	57,384,176 - 57,522,378 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	17	60,548,512 - 60,676,637 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	17	64,551,533 - 64,679,727 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	17	58,705,684 - 58,833,921 (-)	NCBI	Rnor_WKY
Rnor_6.0	17	62,332,537 - 62,462,644 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	62,332,537 - 62,462,644 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	17	64,106,292 - 64,238,150 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	17	66,039,497 - 66,168,042 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	17	58,665,541 - 58,793,343 (-)	NCBI		Celera
Cytogenetic Map	17	q12.1	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Crohn's disease (ISO)

ulcerative colitis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

4-hydroxyphenyl retinamide (ISO)

acrolein (ISO)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

amphetamine (EXP)

aristolochic acid A (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (EXP)

caffeine (ISO)

carbamazepine (ISO)

carbon nanotube (ISO)

chloroprene (ISO)

choline (ISO)

cisplatin (ISO)

cobalt dichloride (ISO)

deoxynivalenol (ISO)

dioxygen (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

ethanol (ISO)

finasteride (EXP)

folic acid (ISO)

fulvestrant (ISO)

gentamycin (EXP)

hydrogen peroxide (ISO)

ivermectin (ISO)

L-methionine (ISO)

methapyrilene (ISO)

methyl methanesulfonate (ISO)

ozone (ISO)

paracetamol (ISO)

phenobarbital (ISO)

potassium chromate (ISO)

Salinomycin (ISO)

SB 431542 (ISO)

succimer (ISO)

testosterone (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

G2/M transition of mitotic cell cycle (ISO)

positive regulation of autophagy (ISO)

positive regulation of cyclin-dependent protein serine/threonine kinase activity (ISO)

regulation of canonical Wnt signaling pathway (IBA,ISO)

regulation of protein kinase activity (IBA)

Cellular Component

cyclin-dependent protein kinase holoenzyme complex (ISO)

cytoplasmic cyclin-dependent protein kinase holoenzyme complex (IBA,ISO)

nucleus (ISO)

plasma membrane (IBA,ISO)

Molecular Function

cyclin-dependent protein serine/threonine kinase activator activity (IBA)

cyclin-dependent protein serine/threonine kinase regulator activity (ISO)

protein binding (ISO)

protein kinase binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:19524571	PMID:20059949	PMID:23376485	PMID:26220330	PMID:28241067

Genomics

Comparative Map Data

Ccny
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	17	57,385,002 - 57,512,860 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	17	57,384,176 - 57,522,378 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	17	60,548,512 - 60,676,637 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	17	64,551,533 - 64,679,727 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	17	58,705,684 - 58,833,921 (-)	NCBI	Rnor_WKY
Rnor_6.0	17	62,332,537 - 62,462,644 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	62,332,537 - 62,462,644 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	17	64,106,292 - 64,238,150 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	17	66,039,497 - 66,168,042 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	17	58,665,541 - 58,793,343 (-)	NCBI		Celera
Cytogenetic Map	17	q12.1	NCBI

CCNY
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	35,247,025 - 35,572,667 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	10	35,247,025 - 35,572,669 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	35,535,953 - 35,861,595 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	35,575,959 - 35,899,164 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	10	35,575,958 - 35,898,672	NCBI
Celera	10	35,301,299 - 35,625,598 (+)	NCBI		Celera
Cytogenetic Map	10	p11.21	NCBI
HuRef	10	35,254,369 - 35,578,459 (+)	NCBI		HuRef
CHM1_1	10	35,536,901 - 35,860,352 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	10	35,275,620 - 35,601,106 (+)	NCBI		T2T-CHM13v2.0

Ccny
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	18	9,312,304 - 9,450,188 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	18	9,312,304 - 9,450,154 (-)	Ensembl		GRCm39 Ensembl
GRCm38	18	9,312,304 - 9,450,154 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	18	9,312,304 - 9,450,154 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	18	9,314,042 - 9,450,148 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	18	9,314,042 - 9,450,148 (-)	NCBI		MGSCv36	mm8
Celera	18	9,350,201 - 9,486,604 (-)	NCBI		Celera
Cytogenetic Map	18	A1	NCBI

Ccny
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955462	5,937,292 - 6,088,310 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955462	5,937,292 - 6,088,310 (-)	NCBI	ChiLan1.0	ChiLan1.0

CCNY
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	10	35,950,490 - 36,273,282 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	36,035,729 - 36,273,282 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	10	35,458,092 - 35,698,142 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

CCNY
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	1,387,962 - 1,720,497 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	1,390,082 - 1,720,357 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	1,476,374 - 1,808,633 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	1,670,014 - 2,003,475 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	1,671,101 - 1,919,834 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	1,441,682 - 1,774,513 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	1,484,477 - 1,818,050 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	1,605,744 - 1,938,890 (-)	NCBI		UU_Cfam_GSD_1.0

Ccny
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	14,138,557 - 14,349,544 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936574	3,638,048 - 3,849,736 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936574	3,638,054 - 3,849,154 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CCNY
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	10	57,929,244 - 58,086,872 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	10	57,929,484 - 58,057,964 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	10	63,625,440 - 63,709,347 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CCNY
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	34,626,185 - 34,847,835 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	34,626,323 - 34,848,918 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666056	43,780,187 - 44,014,772 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ccny
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624805	10,033,112 - 10,199,398 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Ccny
536 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	28
Count of miRNA genes:	27
Interacting mature miRNAs:	27
Transcripts:	ENSRNOT00000024545
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354658	Spl8	Serum phospholipid level QTL 8	3.8		blood VLDL phospholipid amount (VT:0010507)	blood very low density lipoprotein phospholipid level (CMO:0001571)	17	1	60781592	Rat
1354581	Bp247	Blood pressure QTL 247	4.5		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	17	1	69599340	Rat
1354662	Rf49	Renal function QTL 49	2.9		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	17	1	69599340	Rat
1354596	Bw32	Body weight QTL 32	4.5		body mass (VT:0001259)	body weight (CMO:0000012)	17	4299130	60781592	Rat
1354630	Cm34	Cardiac mass QTL 34	8.7		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	17	4299130	69599340	Rat
1354638	Insul1	Insulin level QTL 1	4.8		blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	17	4299130	69599340	Rat
1354651	Lmblg2	Limb length QTL 2	6		tibia length (VT:0004357)	tibia length (CMO:0000450)	17	4299130	69599340	Rat
1354640	Scl32	Serum cholesterol level QTL 32	5.4		blood HDL cholesterol amount (VT:0000184)	blood high density lipoprotein cholesterol level (CMO:0000052)	17	15781592	60781592	Rat
1354659	Scl68	Serum cholesterol level QTL 68	3.9		blood VLDL cholesterol amount (VT:0005144)	blood very low density lipoprotein cholesterol level (CMO:0000648)	17	15781592	60781592	Rat
7394837	Memor18	Memory QTL 18			exploratory behavior trait (VT:0010471)	measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)	17	18640182	63640182	Rat
1354628	Stl13	Serum triglyceride level QTL 13	3.8		blood triglyceride amount (VT:0002644)	blood triglyceride level (CMO:0000118)	17	21293039	60781592	Rat
61394	Bp8	Blood pressure QTL 8	2.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	17	23080567	59555013	Rat
12903978	Cm118	Cardiac mass QTL 118		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	17	23653184	68653184	Rat
12903979	Cm119	Cardiac mass QTL 119		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	17	23653184	68653184	Rat
12903980	Cm120	Cardiac mass QTL 120		0.002	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	17	23653184	68653184	Rat
12903981	Am17	Aortic mass QTL 17		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	17	23653184	68653184	Rat
1559055	Bp278	Blood pressure QTL 278		0.04	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	17	23653184	68653184	Rat
12903982	Kidm70	Kidney mass QTL 70		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	17	23653184	70974005	Rat
1354619	Bp242	Blood pressure QTL 242	6.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	17	24599340	69599340	Rat
4889955	Bss93	Bone structure and strength QTL 93	4.4		tibia size trait (VT:0100001)	tibia cortical bone volume to tibia total bone volume ratio (CMO:0001727)	17	27027949	60463643	Rat
8552928	Pigfal9	Plasma insulin-like growth factor 1 level QTL 9	9		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	17	28409147	73409147	Rat
9590107	Sffal7	Serum free fatty acids level QTL 7	4.81	0.001	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	17	28409147	73409147	Rat
10450503	Bp386	Blood pressure QTL 386		0.28	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	17	31368391	62109574	Rat
2324621	Coatc5	Coat color QTL 5			coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	17	31368391	73951021	Rat
724549	Niddm56	Non-insulin dependent diabetes mellitus QTL 56		0.03	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	17	31990784	76990784	Rat
1354663	Bvd5	Brain ventricular dilatation QTL 5	3.51	0.001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	17	31990784	81292925	Rat
1300148	Bp192	Blood pressure QTL 192	3.47		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	17	34550843	73951021	Rat
724528	Uae4	Urinary albumin excretion QTL 4	4.9	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	17	35837085	69599340	Rat
2301412	Kidm40	Kidney mass QTL 40		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	17	37479847	82479847	Rat
2317054	Aia12	Adjuvant induced arthritis QTL 12	4.24		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	17	38281509	83281509	Rat
2317060	Aia26	Adjuvant induced arthritis QTL 26	3.22		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	17	38281509	83281509	Rat
1598871	Memor5	Memory QTL 5	5.3		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	17	40540041	80387013	Rat
1358295	Aocep1	Aortic cell protein QTL 1	6.1	0.00000071	thoracic aorta cellular protein amount (VT:0010598)	aortic cell percentage	17	40990005	85990005	Rat
631497	Bp98	Blood pressure QTL 98	3.66		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	17	41354651	60463643	Rat
1354635	Bp245	Blood pressure QTL 245	6		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	17	42073160	69599340	Rat
1354635	Bp245	Blood pressure QTL 245	6		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	17	42073160	69599340	Rat
7411575	Bw140	Body weight QTL 140	30.2	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	17	48560935	86533673	Rat
8694181	Bw151	Body weight QTL 151	4.36	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	17	48560935	86533673	Rat
2317038	Ginf3	Gastrointestinal inflammation QTL 3	2.89	0.005	liver integrity trait (VT:0010547)	liver granuloma severity score (CMO:0002157)	17	49920154	86533673	Rat
2303580	Gluco49	Glucose level QTL 49	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	17	50040271	86533673	Rat
1354629	Scl31	Serum cholesterol level QTL 31	4.1		blood cholesterol amount (VT:0000180)	blood total cholesterol level (CMO:0000051)	17	50890908	60781592	Rat
1354654	Spl7	Serum phospholipid level QTL 7	5.5		blood phospholipid amount (VT:0006084)	blood phospholipid level (CMO:0001169)	17	50890908	60781592	Rat
4889894	Eae33	Experimental allergic encephalomyelitis QTL 33	5.2	0.0001	nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis severity score (CMO:0001419)	17	50909099	86022412	Rat
2317053	Aia25	Adjuvant induced arthritis QTL 25	2.69		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	17	50909196	60781426	Rat
1354588	Bvd4	Brain ventricular dilatation QTL 4	5.31	0.001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	17	53498828	82479847	Rat
61466	Niddm12	Non-insulin dependent diabetes mellitus QTL 12	3.2	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	17	54029929	60463637	Rat
70210	Cm15	Cardiac mass QTL 15	6.5		heart right ventricle mass (VT:0007033)	heart right ventricle wet weight (CMO:0000072)	17	57246723	70156904	Rat
1600398	Edcs5	Endometrial carcinoma susceptibility QTL 5	2.2		uterus morphology trait (VT:0001120)	percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)	17	57246723	70852846	Rat
2302365	Gluco40	Glucose level QTL 40	4.79		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	17	57246843	82046127	Rat

Markers in Region

RH137311

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	17	57,384,843 - 57,385,023 (+)	MAPPER	mRatBN7.2
Rnor_6.0	17	62,332,379 - 62,332,558	NCBI	Rnor6.0
Rnor_5.0	17	64,106,134 - 64,106,313	UniSTS	Rnor5.0
RGSC_v3.4	17	66,039,339 - 66,039,518	UniSTS	RGSC3.4
Celera	17	58,665,383 - 58,665,562	UniSTS
RH 3.4 Map	17	608.3	UniSTS
Cytogenetic Map	17	q12.1	UniSTS

ha3046

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	17	57,421,918 - 57,423,478 (+)	MAPPER	mRatBN7.2
Rnor_6.0	17	62,369,201 - 62,370,760	NCBI	Rnor6.0
Rnor_5.0	17	64,142,956 - 64,144,515	UniSTS	Rnor5.0
RGSC_v3.4	17	66,076,435 - 66,077,994	UniSTS	RGSC3.4
Celera	17	58,702,457 - 58,704,016	UniSTS
Cytogenetic Map	17	q12.1	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	43	57	41	19	41	8	11	74	35	41	11	8
Low
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001191833	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474080	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000293	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000024545 ⟹ ENSRNOP00000024545

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	17	57,384,176 - 57,512,860 (-)	Ensembl
Rnor_6.0 Ensembl	17	62,332,537 - 62,462,644 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000099842 ⟹ ENSRNOP00000082775

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	17	57,385,002 - 57,522,378 (-)	Ensembl

RefSeq Acc Id:

NM_001191833 ⟹ NP_001178762

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	17	57,385,002 - 57,512,860 (-)	NCBI
Rnor_6.0	17	62,332,537 - 62,462,644 (-)	NCBI
Rnor_5.0	17	64,106,292 - 64,238,150 (-)	NCBI
Celera	17	58,665,541 - 58,793,343 (-)	NCBI

Sequence:

show sequence

ATGGGGAACACAACTTCGTGCTGCGTGTCGTCCAGCCCTAAGCTCCGGAGGAATGCGCACTCGC
GGCTGGAGTCCTACCGCCCGGACACGGACCTCAGCCGCGAGGACACTGGCTGCAATCTGCAGCA
CATCAGCGACCGGGAAAACATCGACGATTTAAACATGGAATTCAATCCTTCAGACCATCCTCGG
GCCAGCACAATATTCCTCAGCAAATCTCAGACAGACGTGAGAGAAAAACGAAAGAGTCTCTTCA
TTAACCATCATCCTCCAGGGCAGACATCAAGGAAATACAGTTCCTGCTCCACCATCTTTCTAGA
CGACAGCACAGTCAGCCAGCCAAACCTCAAGTACACCATCAAATGTGTAGCTCTTGCGATATAT
TACCACATCAAAAACAGGGACCCAGATGGAAGGATGCTCTTAGATATTTTTGATGAAAACCTCC
ACCCTCTTTCGAAATCCGAAGTGCCACCAGATTATGACAAACACAACCCAGAGCAGAAGCAGAT
TTACCGGTTCGTTCGGACACTGTTCAGTGCTGCTCAGCTGACAGCTGAATGTGCCATTGTCACC
CTGGTATACCTTGAAAGGCTCTTGACATATGCAGAGATTGACATTTGTCCAGCCAATTGGAAGC
GCATTGTTCTAGGAGCTATCCTGCTGGCCTCTAAGGTGTGGGATGACCAGGCTGTGTGGAATGT
GGACTACTGCCAGATCCTGAAAGACATCACAGTGGAGGACATGAATGAACTGGAACGCCAGTTC
CTTGAATTGCTACAGTTTAACATCAATGTTCCTTCCAGTGTGTATGCCAAGTATTATTTTGATC
TGCGTTCTCTGGCAGAAGCAAACAGCCTGAGCTTTCCTCTGGAGCCCCTGAGCAGGGAGCGTGC
CCACAAGCTGGAGGCCATCTCTCGTCTCTGTGAGGACAAGTACAAGGACCTCAGAAAACCCATG
AGGAAGCGTTCAGCAAGTGCTGACAACCTGATTCTGCCTCGGTGGTCCCCAGCCATCATCTCCT
AACTGGGGCACTCTCCTGAGGCCATGCCGTCCCTCATCTTCTCCTTTTGTTTAAGAAAAGATGA
ACTTGGATGGTTTGGTTTGGTTTGGTTTTCTTTTTTCCTTCTGTTTTTAACGCAGCCCCGTCAA
GGCTGCCTTCACACCCACCTCCACGTTGCGTGGGTGTACACAAAGAGGCTTTAAGGGACGTAAA
ATCAGTATTCAGGAAACTCGGTGTCAAGCCTTCGCAGCAGTCACCAACAGCGCTTCTTTCATGG
AGGAAACAGACTCTAATCCTGGAGAAGGAAATGAAGGAAAAGGAAGTTGTGTTGAGGCAAAGAT
TAGTTGGGAGCTTTGCTGTTTCTGGGTTTCTGTCTGGTCATAGACACCAGATGGAGGCAGATGG
TAGGTAGCAGAGTTGAAGGCACCTCCAAATCCGGAATGCCATGCTATG

hide sequence

Protein Sequences


Protein RefSeqs	NP_001178762	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL83778	(Get FASTA)	NCBI Sequence Viewer
	EDL83779	(Get FASTA)	NCBI Sequence Viewer
	EDL83780	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001178762 ⟸ NM_001191833

- UniProtKB:

F1MA89 (UniProtKB/TrEMBL), A0A8I5ZU57 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGNTTSCCVSSSPKLRRNAHSRLESYRPDTDLSREDTGCNLQHISDRENIDDLNMEFNPSDHPR
ASTIFLSKSQTDVREKRKSLFINHHPPGQTSRKYSSCSTIFLDDSTVSQPNLKYTIKCVALAIY
YHIKNRDPDGRMLLDIFDENLHPLSKSEVPPDYDKHNPEQKQIYRFVRTLFSAAQLTAECAIVT
LVYLERLLTYAEIDICPANWKRIVLGAILLASKVWDDQAVWNVDYCQILKDITVEDMNELERQF
LELLQFNINVPSSVYAKYYFDLRSLAEANSLSFPLEPLSRERAHKLEAISRLCEDKYKDLRKPM
RKRSASADNLILPRWSPAIIS

hide sequence

RefSeq Acc Id:

ENSRNOP00000024545 ⟸ ENSRNOT00000024545

RefSeq Acc Id:

ENSRNOP00000082775 ⟸ ENSRNOT00000099842

Protein Domains

CYCLIN

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1MA89-F1-model_v2	AlphaFold	F1MA89	1-341	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1565969	AgrOrtholog
BioCyc Gene	G2FUF-8948	BioCyc
Ensembl Genes	ENSRNOG00000018123	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000024545.5	UniProtKB/TrEMBL
	ENSRNOP00000082775	ENTREZGENE
	ENSRNOP00000082775.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000024545.5	UniProtKB/TrEMBL
	ENSRNOT00000099842	ENTREZGENE
	ENSRNOT00000099842.1	UniProtKB/TrEMBL
InterPro	Cyclin-like	UniProtKB/TrEMBL
	Cyclin-like_sf	UniProtKB/TrEMBL
	Cyclin_N	UniProtKB/TrEMBL
	Cyclin_Y	UniProtKB/TrEMBL
KEGG Report	rno:361261	UniProtKB/TrEMBL
NCBI Gene	361261	ENTREZGENE
Pfam	Cyclin_N	UniProtKB/TrEMBL
PhenoGen	Ccny	PhenoGen
PIRSF	Cyclin_CG14939	UniProtKB/TrEMBL
SMART	CYCLIN	UniProtKB/TrEMBL
Superfamily-SCOP	Cyclin_like	UniProtKB/TrEMBL
UniProt	A0A8I5ZU57	ENTREZGENE, UniProtKB/TrEMBL
	F1MA89	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-06	Ccny	cyclin Y	RGD1565969_predicted	similar to 5730405I09Rik protein (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1565969_predicted	similar to 5730405I09Rik protein (predicted)	LOC361261	similar to 5730405I09Rik protein	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC361261	similar to 5730405I09Rik protein			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD