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Gene: Amph (amphiphysin) Rattus norvegicus
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Symbol: Amph
Name: amphiphysin
Description: Exhibits protein C-terminus binding activity and protein heterodimerization activity. Involved in positive regulation of GTPase activity and positive regulation of endocytosis. Localizes to the axon terminus and extrinsic component of synaptic vesicle membrane. Orthologous to human AMPH (amphiphysin); PARTICIPATES IN Fc gamma receptor mediated signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Amph1; amphiphysin 1; LOC687233; similar to amphiphysin 1
Orthologs:
Homo sapiens (human) : AMPH (amphiphysin)  HGNC  Alliance
Mus musculus (house mouse) : Amph (amphiphysin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Amph (amphiphysin)
Pan paniscus (bonobo/pygmy chimpanzee) : AMPH (amphiphysin)
Canis lupus familiaris (dog) : AMPH (amphiphysin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Amph (amphiphysin)
Sus scrofa (pig) : AMPH (amphiphysin)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01748,304,324 - 48,562,838 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01746,357,604 - 46,621,763 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41753,558,804 - 53,802,936NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11753,561,655 - 53,805,777NCBI
Cytogenetic Map17q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Amph
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620274
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.