Akr1e2 (aldo-keto reductase family 1, member E2) - Rat Genome Database

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Gene: Akr1e2 (aldo-keto reductase family 1, member E2) Rattus norvegicus
Analyze
Symbol: Akr1e2
Name: aldo-keto reductase family 1, member E2
RGD ID: 1309599
Description: Predicted to enable alditol:NADP+ 1-oxidoreductase activity. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Orthologous to human AKR1E2 (aldo-keto reductase family 1 member E2); INTERACTS WITH (+)-schisandrin B; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 1,5-anhydro-D-fructose reductase; AF reductase; Akr1cl2; Akr1e1; aldo-keto reductase family 1 member C-like protein 2; aldo-keto reductase family 1 member E2; aldo-keto reductase family 1, member C-like 2; aldo-keto reductase family 1, member E1; LOC307091; MGC105536
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81770,645,835 - 70,660,366 (+)NCBIGRCr8
mRatBN7.21765,735,909 - 65,750,441 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1765,735,943 - 65,750,441 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1769,231,629 - 69,246,118 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01773,060,477 - 73,074,961 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01767,103,460 - 67,117,949 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01769,365,437 - 69,379,944 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1769,365,453 - 69,379,947 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01771,079,217 - 71,093,701 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41777,011,336 - 77,025,824 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11777,022,168 - 77,036,651 (+)NCBI
Celera1765,268,655 - 65,283,123 (+)NCBICelera
Cytogenetic Map17q12.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IBA,IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15118078   PMID:23376485  


Genomics

Comparative Map Data
Akr1e2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81770,645,835 - 70,660,366 (+)NCBIGRCr8
mRatBN7.21765,735,909 - 65,750,441 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1765,735,943 - 65,750,441 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1769,231,629 - 69,246,118 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01773,060,477 - 73,074,961 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01767,103,460 - 67,117,949 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01769,365,437 - 69,379,944 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1769,365,453 - 69,379,947 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01771,079,217 - 71,093,701 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41777,011,336 - 77,025,824 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11777,022,168 - 77,036,651 (+)NCBI
Celera1765,268,655 - 65,283,123 (+)NCBICelera
Cytogenetic Map17q12.2NCBI
AKR1E2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38104,824,973 - 4,873,237 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl104,786,629 - 4,848,062 (+)EnsemblGRCh38hg38GRCh38
GRCh37104,868,369 - 4,890,254 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36104,858,402 - 4,880,254 (+)NCBINCBI36Build 36hg18NCBI36
Build 34104,858,425 - 4,880,249NCBI
Celera104,811,323 - 4,833,177 (+)NCBICelera
Cytogenetic Map10p15.1NCBI
HuRef104,802,403 - 4,824,264 (+)NCBIHuRef
CHM1_1104,868,717 - 4,890,574 (+)NCBICHM1_1
T2T-CHM13v2.0104,825,330 - 4,873,573 (+)NCBIT2T-CHM13v2.0
Akr1e1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39134,641,122 - 4,659,163 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl134,640,749 - 4,659,173 (-)EnsemblGRCm39 Ensembl
GRCm38134,591,123 - 4,609,164 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl134,590,750 - 4,609,174 (-)EnsemblGRCm38mm10GRCm38
MGSCv37134,591,736 - 4,608,410 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36134,591,777 - 4,608,381 (-)NCBIMGSCv36mm8
Celera134,571,016 - 4,587,416 (-)NCBICelera
Cytogenetic Map13A1NCBI
cM Map132.57NCBI
Akr1e2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955429715,157 - 731,303 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955429714,843 - 731,285 (-)NCBIChiLan1.0ChiLan1.0
AKR1E2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2817,376,873 - 17,506,881 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11017,379,890 - 17,404,469 (+)NCBINHGRI_mPanPan1
PanPan1.1104,850,001 - 4,872,215 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl104,850,001 - 4,872,210 (+)Ensemblpanpan1.1panPan2
AKR1E2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1230,694,119 - 30,706,693 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl230,694,249 - 30,706,637 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha227,723,671 - 27,736,248 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0231,074,880 - 31,087,459 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl231,074,883 - 31,087,898 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1228,164,234 - 28,176,774 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0229,001,557 - 29,014,106 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0229,725,464 - 29,738,044 (-)NCBIUU_Cfam_GSD_1.0
Akr1e2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934433,305,613 - 33,325,444 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364849,474,458 - 9,490,676 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364849,472,920 - 9,490,624 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AKR1E2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1065,680,332 - 65,702,190 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11065,680,314 - 65,704,701 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21072,108,978 - 72,133,547 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AKR1E2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.195,012,793 - 5,033,946 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl95,013,032 - 5,033,947 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605110,188,747 - 10,209,140 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Akr1e2
20 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:31
Count of miRNA genes:29
Interacting mature miRNAs:30
Transcripts:ENSRNOT00000023133
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2317045Aia11Adjuvant induced arthritis QTL 114.06joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)176078142686533673Rat
2317054Aia12Adjuvant induced arthritis QTL 124.24joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)173828150983281509Rat
2317060Aia26Adjuvant induced arthritis QTL 263.22joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)173828150983281509Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)173136839173951021Rat
4889894Eae33Experimental allergic encephalomyelitis QTL 335.20.0001nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)175090909986022412Rat
8552928Pigfal9Plasma insulin-like growth factor 1 level QTL 99blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)172840914773409147Rat
9590107Sffal7Serum free fatty acids level QTL 74.810.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)172840914773409147Rat
631502Cm26Cardiac mass QTL 263.71heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)176570358081153923Rat
7411577Bw141Body weight QTL 1410.001body mass (VT:0001259)body weight gain (CMO:0000420)176261951686533673Rat
7411575Bw140Body weight QTL 14030.20.001body mass (VT:0001259)body weight gain (CMO:0000420)174856093586533673Rat
7488963Bp369Blood pressure QTL 3690.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)175900564977910000Rat
8694181Bw151Body weight QTL 1514.360.001body mass (VT:0001259)body weight gain (CMO:0000420)174856093586533673Rat
1300131Bp193Blood pressure QTL 1933.3arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)176364000973951021Rat
1300148Bp192Blood pressure QTL 1923.47arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)173455084373951021Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
1354619Bp242Blood pressure QTL 2426.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172459934069599340Rat
1354630Cm34Cardiac mass QTL 348.7heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)17429913069599340Rat
1354635Bp245Blood pressure QTL 2456arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)174207316069599340Rat
1354635Bp245Blood pressure QTL 2456arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)174207316069599340Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)17429913069599340Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173199078481292925Rat
1354588Bvd4Brain ventricular dilatation QTL 45.310.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)175349882882479847Rat
1358295Aocep1Aortic cell protein QTL 16.10.00000071thoracic aorta cellular protein amount (VT:0010598)aortic cell percentage174099000585990005Rat
1559055Bp278Blood pressure QTL 2780.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318468653184Rat
1598871Memor5Memory QTL 55.3exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)174054004180387013Rat
70210Cm15Cardiac mass QTL 156.5heart right ventricle mass (VT:0007033)heart right ventricle wet weight (CMO:0000072)175724672370156904Rat
724528Uae4Urinary albumin excretion QTL 44.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)173583708569599340Rat
2303580Gluco49Glucose level QTL 492blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)175004027186533673Rat
724549Niddm56Non-insulin dependent diabetes mellitus QTL 560.03blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)173199078476990784Rat
12903978Cm118Cardiac mass QTL 1180.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)172365318468653184Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)173747984782479847Rat
2302365Gluco40Glucose level QTL 404.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)175724684382046127Rat
12903980Cm120Cardiac mass QTL 1200.002heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)172365318468653184Rat
12903982Kidm70Kidney mass QTL 700.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)172365318470974005Rat
12903979Cm119Cardiac mass QTL 1190.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172365318468653184Rat
2317038Ginf3Gastrointestinal inflammation QTL 32.890.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)174992015486533673Rat
12903981Am17Aortic mass QTL 170.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)172365318468653184Rat
1600398Edcs5Endometrial carcinoma susceptibility QTL 52.2uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)175724672370852846Rat

Markers in Region
RH127938  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21765,750,099 - 65,750,288 (+)MAPPERmRatBN7.2
Rnor_6.01769,379,603 - 69,379,791NCBIRnor6.0
Rnor_5.01771,093,360 - 71,093,548UniSTSRnor5.0
RGSC_v3.41777,025,483 - 77,025,671UniSTSRGSC3.4
Celera1765,282,782 - 65,282,970UniSTS
RH 3.4 Map17637.9UniSTS
Cytogenetic Map17q12.3UniSTS
BE121379  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21765,736,321 - 65,736,472 (+)MAPPERmRatBN7.2
Rnor_6.01769,365,826 - 69,365,976NCBIRnor6.0
Rnor_5.01771,079,583 - 71,079,733UniSTSRnor5.0
RGSC_v3.41777,011,702 - 77,011,852UniSTSRGSC3.4
Celera1765,269,022 - 65,269,172UniSTS
RH 3.4 Map17637.4UniSTS
Cytogenetic Map17q12.3UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 7 56 41 15 41 68 31 30 10
Low 36 1 4 8 11 6 4 11 1 8
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000023133   ⟹   ENSRNOP00000023133
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1765,735,943 - 65,750,435 (+)Ensembl
Rnor_6.0 Ensembl1769,365,453 - 69,379,947 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000109731   ⟹   ENSRNOP00000083564
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1765,736,023 - 65,750,441 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000113194   ⟹   ENSRNOP00000087312
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1765,737,747 - 65,750,441 (+)Ensembl
RefSeq Acc Id: NM_001008342   ⟹   NP_001008343
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81770,645,882 - 70,660,366 (+)NCBI
mRatBN7.21765,735,956 - 65,750,441 (+)NCBI
Rnor_6.01769,365,460 - 69,379,944 (+)NCBI
Rnor_5.01771,079,217 - 71,093,701 (+)NCBI
RGSC_v3.41777,011,336 - 77,025,824 (+)RGD
Celera1765,268,655 - 65,283,123 (+)RGD
Sequence:
RefSeq Acc Id: XM_008771865   ⟹   XP_008770087
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81770,645,835 - 70,660,366 (+)NCBI
mRatBN7.21765,735,909 - 65,750,441 (+)NCBI
Rnor_6.01769,365,437 - 69,379,944 (+)NCBI
Sequence:
RefSeq Acc Id: NP_001008343   ⟸   NM_001008342
- UniProtKB: Q5U1Y4 (UniProtKB/Swiss-Prot),   A0A8I6GF05 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008770087   ⟸   XM_008771865
- Peptide Label: isoform X1
- UniProtKB: A0A8I6GF05 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000023133   ⟸   ENSRNOT00000023133
RefSeq Acc Id: ENSRNOP00000083564   ⟸   ENSRNOT00000109731
RefSeq Acc Id: ENSRNOP00000087312   ⟸   ENSRNOT00000113194
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5U1Y4-F1-model_v2 AlphaFold Q5U1Y4 1-301 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700541
Promoter ID:EPDNEW_R11064
Type:initiation region
Name:Akr1e2_1
Description:aldo-keto reductase family 1, member E2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01769,365,478 - 69,365,538EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309599 AgrOrtholog
BioCyc Gene G2FUF-8843 BioCyc
Ensembl Genes ENSRNOG00000017165 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055018208 UniProtKB/Swiss-Prot
  ENSRNOG00060016684 UniProtKB/Swiss-Prot
  ENSRNOG00065003462 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000023133 ENTREZGENE
  ENSRNOT00000023133.8 UniProtKB/Swiss-Prot
  ENSRNOT00000109731.1 UniProtKB/TrEMBL
  ENSRNOT00000113194.1 UniProtKB/TrEMBL
  ENSRNOT00055030943 UniProtKB/Swiss-Prot
  ENSRNOT00060028940 UniProtKB/Swiss-Prot
  ENSRNOT00065004925 UniProtKB/Swiss-Prot
Gene3D-CATH 3.20.20.100 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7302893 IMAGE-MGC_LOAD
InterPro AKR UniProtKB/TrEMBL
  Aldo/ket_reductase_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Aldo/keto_reductase UniProtKB/Swiss-Prot
  NADP_OxRdtase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NADP_OxRdtase_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:307091 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105536 IMAGE-MGC_LOAD
NCBI Gene 307091 ENTREZGENE
PANTHER 1,5-ANHYDRO-D-FRUCTOSE REDUCTASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ALDO/KETO REDUCTASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Aldo_ket_red UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Akr1e2 PhenoGen
PIRSF AKR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS ALDKETRDTASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ALDOKETO_REDUCTASE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ALDOKETO_REDUCTASE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ALDOKETO_REDUCTASE_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000017165 RatGTEx
  ENSRNOG00055018208 RatGTEx
  ENSRNOG00060016684 RatGTEx
  ENSRNOG00065003462 RatGTEx
Superfamily-SCOP SSF51430 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZXF6_RAT UniProtKB/TrEMBL
  A0A8I6GF05 ENTREZGENE, UniProtKB/TrEMBL
  AKCL2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-02 Akr1e2  aldo-keto reductase family 1, member E2  Akr1cl2  aldo-keto reductase family 1, member C-like 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-26 Akr1cl2  aldo-keto reductase family 1, member C-like 2  Akr1e1  aldo-keto reductase family 1, member E1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Akr1e1  aldo-keto reductase family 1, member E1  Akr1e1_predicted  aldo-keto reductase family 1, member E1 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Akr1e1_predicted  aldo-keto reductase family 1, member E1 (predicted)      Symbol and Name status set to approved 70820 APPROVED