Gene: Dusp22 (dual specificity phosphatase 22) Rattus norvegicus
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Symbol: Dusp22
Name: dual specificity phosphatase 22
Description: ENCODES a protein that exhibits non-membrane spanning protein tyrosine phosphatase activity (ortholog); protein tyrosine kinase binding (ortholog); protein tyrosine phosphatase activity (ortholog); INVOLVED IN cellular response to epidermal growth factor stimulus (ortholog); negative regulation of cell migration (ortholog); negative regulation of focal adhesion assembly (ortholog); PARTICIPATES IN mitogen activated protein kinase signaling pathway; FOUND IN cytoplasm (ortholog); filamentous actin (ortholog); leading edge of lamellipodium (ortholog); INTERACTS WITH 2,6-dinitrotoluene; dieldrin; finasteride
AGR Description: Predicted to have non-membrane spanning protein tyrosine phosphatase activity and protein tyrosine kinase binding activity; predicted to be involved in several processes, including cellular response to growth factor stimulus, negative regulation of cell adhesion, and negative regulation of cellular metabolic process; predicted to localize to several cellular components, including the cytosol, filamentous actin, and leading edge of lamellipodium; orthologous to human DUSP22 (dual specificity phosphatase 22).
Merged Description: Predicted to have non-membrane spanning protein tyrosine phosphatase activity and protein tyrosine kinase binding activity; predicted to be involved in several processes, including cellular response to growth factor stimulus, negative regulation of cell adhesion, and negative regulation of cellular metabolic process; predicted to localize to several cellular components, including the cytosol, filamentous actin, and leading edge of lamellipodium; orthologous to human DUSP22 (dual specificity phosphatase 22); PARTICIPATES IN mitogen activated protein kinase signaling pathway; INTERACTS WITH 2,6-dinitrotoluene; dieldrin; finasteride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: dual specificity protein phosphatase 22; LOC361242
Orthologs:
Homo sapiens (human) : DUSP22 (dual specificity phosphatase 22)  HGNC  Alliance
Mus musculus (house mouse) : Dusp22 (dual specificity phosphatase 22)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dusp22 (dual specificity phosphatase 22)
Pan paniscus (bonobo/pygmy chimpanzee) : DUSP22 (dual specificity phosphatase 22)
Canis lupus familiaris (dog) : DUSP22 (dual specificity phosphatase 22)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dusp22 (dual specificity phosphatase 22)
Sus scrofa (pig) : DUSP22 (dual specificity phosphatase 22)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01734,986,589 - 35,037,297 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01738,366,974 - 38,417,681 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41740,229,790 - 40,281,414 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11740,232,640 - 40,394,580 (-)NCBI
Celera1733,321,675 - 33,372,005 (-)NCBICelera
Cytogenetic Map17p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


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References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
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QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
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Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Dusp22
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307146
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.