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Gene: Pfkfb3 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3) Rattus norvegicus
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Symbol: Pfkfb3
Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
Description: Predicted to have 6-phosphofructo-2-kinase activity and fructose-2,6-bisphosphate 2-phosphatase activity. Involved in brain development and fructose 2,6-bisphosphate metabolic process. Predicted to localize to the cytosol and nucleoplasm. Orthologous to human PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3); PARTICIPATES IN hypoxia inducible factor pathway; fructose and mannose metabolic pathway; glycolysis pathway; INTERACTS WITH 6-propyl-2-thiouracil; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3; 6PF-2-K/Fru-2,6-P2ase 3; 6PF-2-K/Fru-2,6-P2ASE brain-type isozyme; PFK/FBPase 3; RB2K
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01770,632,778 - 70,713,736 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01772,334,950 - 72,416,018 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41778,241,182 - 78,268,272 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11778,252,014 - 78,279,105 (+)NCBI
Celera1766,539,556 - 66,566,619 (+)NCBICelera
Cytogenetic Map17q12.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pfkfb3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 619776
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.