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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,1-dichloroethene | decreases expression | ISO | RGD:732387 | 6480464 | vinylidene chloride results in decreased expression of SLC17A1 mRNA | CTD | PMID:26682919 | 1-naphthyl isothiocyanate | decreases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in decreased expression of SLC17A1 mRNA | CTD | PMID:25380136 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SLC17A1 mRNA | CTD | PMID:16054898, PMID:20558275 | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2, 6-dinitrotoluene affects the expression of SLC17A1 mRNA | CTD | PMID:21346803 | 2-amino-2-deoxy-D-glucopyranose | increases expression | ISO | RGD:732387 | 6480464 | Glucosamine results in increased expression of SLC17A1 mRNA | CTD | PMID:17178593 | 3,3',4,4',5-pentachlorobiphenyl | increases expression | EXP | | 6480464 | 3 more ... | CTD | PMID:19692669 | 3-chloropropane-1,2-diol | increases expression | EXP | | 6480464 | alpha-Chlorohydrin results in increased expression of SLC17A1 protein | CTD | PMID:34915118 | 4,4'-diaminodiphenylmethane | affects expression | ISO | RGD:732387 | 6480464 | 4, 4'-diaminodiphenylmethane affects the expression of SLC17A1 mRNA | CTD | PMID:18648102 | 4,4'-sulfonyldiphenol | increases expression | ISO | RGD:732387 | 6480464 | bis(4-hydroxyphenyl)sulfone results in increased expression of SLC17A1 mRNA | CTD | PMID:33297965 | 5-azaorotic acid | multiple interactions | ISO | RGD:732387 | 6480464 | [Oxonic Acid analog co-treated with Hypoxanthine] results in decreased expression of SLC17A1 mRNA more ... | CTD | PMID:34687833 | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of SLC17A1 mRNA | CTD | PMID:31881176 | acyclovir | decreases expression | EXP | | 6480464 | Acyclovir results in decreased expression of SLC17A1 mRNA, Acyclovir results in decreased expression of SLC17A1 protein | CTD | PMID:14675048 | aflatoxin B1 | decreases expression | ISO | RGD:1350724 | 6480464 | Aflatoxin B1 results in decreased expression of SLC17A1 mRNA | CTD | PMID:27153756 | aldehydo-D-glucosamine | increases expression | ISO | RGD:732387 | 6480464 | Glucosamine results in increased expression of SLC17A1 mRNA | CTD | PMID:17178593 | allopurinol | multiple interactions | ISO | RGD:732387 | 6480464 | Allopurinol inhibits the reaction [[Oxonic Acid analog co-treated with Hypoxanthine] results in decreased expression of SLC17A1 mRNA], Allopurinol inhibits the reaction [[Oxonic Acid analog co-treated with Hypoxanthine] results in decreased expression of SLC17A1 protein] | CTD | PMID:34687833 | alpha-hexachlorocyclohexane | increases expression | EXP | | 6480464 | alpha-hexachlorocyclohexane results in increased expression of SLC17A1 mRNA | CTD | PMID:17785943 | arsane | affects methylation | ISO | RGD:1350724 | 6480464 | Arsenic affects the methylation of SLC17A1 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | RGD:1350724 | 6480464 | Arsenic affects the methylation of SLC17A1 gene | CTD | PMID:25304211 | atazanavir sulfate | multiple interactions | ISO | RGD:1350724 | 6480464 | [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of SLC17A1 mRNA | CTD | PMID:33819548 | Benoxacor | decreases expression | ISO | RGD:732387 | 6480464 | benoxacor results in decreased expression of SLC17A1 mRNA | CTD | PMID:34850242 | benzo[a]pyrene | increases mutagenesis | ISO | RGD:1350724 | 6480464 | Benzo(a)pyrene results in increased mutagenesis of SLC17A1 gene | CTD | PMID:25435355 | benzo[a]pyrene | decreases expression | ISO | RGD:1350724 | 6480464 | Benzo(a)pyrene results in decreased expression of SLC17A1 mRNA | CTD | PMID:32234424 | benzo[a]pyrene | increases methylation | ISO | RGD:1350724 | 6480464 | Benzo(a)pyrene results in increased methylation of SLC17A1 5' UTR | CTD | PMID:27901495 | beta-D-glucosamine | increases expression | ISO | RGD:732387 | 6480464 | Glucosamine results in increased expression of SLC17A1 mRNA | CTD | PMID:17178593 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of SLC17A1 mRNA | CTD | PMID:25181051 | C60 fullerene | decreases expression | EXP | | 6480464 | fullerene C60 results in decreased expression of SLC17A1 mRNA | CTD | PMID:19167457 | cadmium atom | increases expression | ISO | RGD:1350724 | 6480464 | Cadmium results in increased expression of SLC17A1 mRNA | CTD | PMID:21120746 | carbon nanotube | increases expression | ISO | RGD:732387 | 6480464 | Nanotubes more ... | CTD | PMID:25620056 | CGP 52608 | multiple interactions | ISO | RGD:1350724 | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to SLC17A1 gene] | CTD | PMID:28238834 | chenodeoxycholic acid | multiple interactions | ISO | RGD:1350724 | 6480464 | [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of SLC17A1 mRNA more ... | CTD | PMID:33819548 | ciguatoxin CTX1B | affects expression | ISO | RGD:732387 | 6480464 | Ciguatoxins affects the expression of SLC17A1 mRNA | CTD | PMID:18353800 | clofibrate | multiple interactions | ISO | RGD:732387 | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of SLC17A1 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of SLC17A1 mRNA] | CTD | PMID:17585979 | clofibric acid | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of SLC17A1 mRNA | CTD | PMID:17602206 | cobalt dichloride | increases expression | EXP | | 6480464 | cobaltous chloride results in increased expression of SLC17A1 mRNA | CTD | PMID:24386269 | coumarin | increases expression | EXP | | 6480464 | coumarin results in increased expression of SLC17A1 mRNA | CTD | PMID:18480146 | cyclosporin A | decreases expression | ISO | RGD:732387 | 6480464 | Cyclosporine results in decreased expression of SLC17A1 mRNA | CTD | PMID:19770486 | cyclosporin A | multiple interactions | ISO | RGD:1350724 | 6480464 | [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Cyclosporine] results in decreased expression of SLC17A1 mRNA | CTD | PMID:33819548 | cyclosporin A | decreases expression | ISO | RGD:1350724 | 6480464 | Cyclosporine results in decreased expression of SLC17A1 mRNA | CTD | PMID:27989131 | deoxycholic acid | multiple interactions | ISO | RGD:1350724 | 6480464 | [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of SLC17A1 mRNA more ... | CTD | PMID:33819548 | dichlorine | multiple interactions | EXP | | 6480464 | [Ozone co-treated with Chlorine] results in decreased expression of SLC17A1 mRNA | CTD | PMID:18636392 | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of SLC17A1 mRNA | CTD | PMID:24136188 | furan | increases expression | ISO | RGD:732387 | 6480464 | furan results in increased expression of SLC17A1 mRNA | CTD | PMID:24183702 | glafenine | decreases expression | EXP | | 6480464 | Glafenine results in decreased expression of SLC17A1 mRNA | CTD | PMID:24136188 | glycochenodeoxycholic acid | multiple interactions | ISO | RGD:1350724 | 6480464 | [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of SLC17A1 mRNA more ... | CTD | PMID:33819548 | glycocholic acid | multiple interactions | ISO | RGD:1350724 | 6480464 | [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of SLC17A1 mRNA more ... | CTD | PMID:33819548 | glycodeoxycholic acid | multiple interactions | ISO | RGD:1350724 | 6480464 | [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of SLC17A1 mRNA more ... | CTD | PMID:33819548 | GW 4064 | increases expression | ISO | RGD:732387 | 6480464 | GW 4064 results in increased expression of SLC17A1 mRNA | CTD | PMID:26655953 | hypoxanthine | multiple interactions | ISO | RGD:732387 | 6480464 | [Oxonic Acid analog co-treated with Hypoxanthine] results in decreased expression of SLC17A1 mRNA more ... | CTD | PMID:34687833 | leflunomide | increases expression | EXP | | 6480464 | leflunomide results in increased expression of SLC17A1 mRNA | CTD | PMID:24136188 | methamphetamine | increases expression | EXP | | 6480464 | Methamphetamine results in increased expression of SLC17A1 mRNA | CTD | PMID:15644446 | methylmercury(1+) | increases expression | EXP | | 6480464 | methylmercury II results in increased expression of SLC17A1 mRNA | CTD | PMID:17905399 | mono(2-ethylhexyl) phthalate | decreases expression | ISO | RGD:732387 | 6480464 | mono-(2-ethylhexyl)phthalate results in decreased expression of SLC17A1 mRNA | CTD | PMID:22401849 | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of SLC17A1 mRNA | CTD | PMID:17602206 | N-nitrosodiethylamine | increases expression | EXP | | 6480464 | Diethylnitrosamine results in increased expression of SLC17A1 mRNA | CTD | PMID:19638242 | N-nitrosodimethylamine | decreases expression | EXP | | 6480464 | Dimethylnitrosamine results in decreased expression of SLC17A1 mRNA | CTD | PMID:17072980, PMID:25380136 | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of SLC17A1 mRNA | CTD | PMID:24136188 | nimesulide | increases expression | EXP | | 6480464 | nimesulide results in increased expression of SLC17A1 mRNA | CTD | PMID:24136188 | nitrofen | increases expression | EXP | | 6480464 | nitrofen results in increased expression of SLC17A1 mRNA | CTD | PMID:33484710 | ochratoxin A | decreases expression | EXP | | 6480464 | ochratoxin A results in decreased expression of SLC17A1 mRNA | CTD | PMID:16251485 | ozone | multiple interactions | EXP | | 6480464 | [Ozone co-treated with Chlorine] results in decreased expression of SLC17A1 mRNA | CTD | PMID:18636392 | p-toluidine | increases expression | EXP | | 6480464 | 4-toluidine results in increased expression of SLC17A1 mRNA | CTD | PMID:27638505 | paracetamol | affects expression | ISO | RGD:732387 | 6480464 | Acetaminophen affects the expression of SLC17A1 mRNA | CTD | PMID:17562736 | paracetamol | multiple interactions | ISO | RGD:1350724 | 6480464 | [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of SLC17A1 mRNA | CTD | PMID:33819548 | paracetamol | multiple interactions | ISO | RGD:732387 | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of SLC17A1 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of SLC17A1 mRNA] | CTD | PMID:17585979 | paraquat | decreases expression | EXP | | 6480464 | Paraquat results in decreased expression of SLC17A1 mRNA | CTD | PMID:18198484 | perfluorononanoic acid | increases expression | ISO | RGD:1350724 | 6480464 | perfluoro-n-nonanoic acid results in increased expression of SLC17A1 mRNA | CTD | PMID:32588087 | perfluorooctane-1-sulfonic acid | decreases expression | EXP | | 6480464 | perfluorooctane sulfonic acid results in decreased expression of SLC17A1 mRNA | CTD | PMID:19162173 | perfluorooctanoic acid | decreases expression | EXP | | 6480464 | perfluorooctanoic acid results in decreased expression of SLC17A1 mRNA | CTD | PMID:19162173 | pirinixic acid | multiple interactions | ISO | RGD:732387 | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of SLC17A1 mRNA | CTD | PMID:19710929 | pirinixic acid | decreases expression | ISO | RGD:732387 | 6480464 | pirinixic acid results in decreased expression of SLC17A1 mRNA | CTD | PMID:23811191 | pirinixic acid | decreases expression | EXP | | 6480464 | pirinixic acid results in decreased expression of SLC17A1 mRNA | CTD | PMID:19162173 | potassium atom | affects expression | EXP | | 6480464 | Potassium affects the expression of SLC17A1 protein | CTD | PMID:11473652 | pravastatin | decreases expression | EXP | | 6480464 | Pravastatin results in decreased expression of SLC17A1 mRNA | CTD | PMID:27225895 | pravastatin | decreases expression | ISO | RGD:732387 | 6480464 | Pravastatin results in decreased expression of SLC17A1 mRNA | CTD | PMID:27225895 | pregnenolone 16alpha-carbonitrile | increases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in increased expression of SLC17A1 mRNA | CTD | PMID:19162173 | pyrazinecarboxamide | increases expression | EXP | | 6480464 | Pyrazinamide results in increased expression of SLC17A1 mRNA | CTD | PMID:22431067 | resveratrol | multiple interactions | ISO | RGD:1350724 | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of SLC17A1 mRNA | CTD | PMID:23557933 | rifampicin | decreases expression | ISO | RGD:1350724 | 6480464 | Rifampin results in decreased expression of SLC17A1 mRNA | CTD | PMID:27199754 | silicon dioxide | decreases expression | ISO | RGD:1350724 | 6480464 | Silicon Dioxide analog results in decreased expression of SLC17A1 mRNA | CTD | PMID:25895662 | tetrachloromethane | affects expression | EXP | | 6480464 | Carbon Tetrachloride affects the expression of SLC17A1 mRNA | CTD | PMID:17805973 | toluene | affects expression | EXP | | 6480464 | Toluene affects the expression of SLC17A1 mRNA | CTD | PMID:18653662 | Triptolide | increases expression | EXP | | 6480464 | triptolide results in increased expression of SLC17A1 protein | CTD | PMID:32519852 | Triptolide | affects expression | ISO | RGD:732387 | 6480464 | triptolide affects the expression of SLC17A1 mRNA | CTD | PMID:32835833 | valproic acid | decreases expression | ISO | RGD:1350724 | 6480464 | Valproic Acid results in decreased expression of SLC17A1 mRNA | CTD | PMID:29154799 | zaragozic acid A | increases expression | EXP | | 6480464 | squalestatin 1 results in increased expression of SLC17A1 mRNA | CTD | PMID:27225895 | zaragozic acid A | affects expression | ISO | RGD:732387 | 6480464 | squalestatin 1 affects the expression of SLC17A1 mRNA | CTD | PMID:27225895 | |