Ank1 (ankyrin 1) - Rat Genome Database
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Gene: Ank1 (ankyrin 1) Rattus norvegicus
Analyze
Symbol: Ank1
Name: ankyrin 1
RGD ID: 1309620
Description: Predicted to have several functions, including enzyme binding activity; ion channel binding activity; and spectrin binding activity. Involved in positive regulation of organelle organization. Localizes to several cellular components, including axolemma; sarcolemma; and sarcomere. Biomarker of transient cerebral ischemia. Human ortholog(s) of this gene implicated in anemia; hereditary spherocytosis; and hereditary spherocytosis type 1. Orthologous to human ANK1 (ankyrin 1); INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ankyrin 1, erythrocytic; ankyrin 1, erythroid; ankyrin-1; LOC306570
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21668,876,294 - 69,054,812 (-)NCBI
Rnor_6.0 Ensembl1673,681,422 - 73,827,488 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01673,681,422 - 73,912,605 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01673,397,821 - 73,459,822 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01673,314,002 - 73,331,197 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41673,333,564 - 73,437,926 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11673,333,832 - 73,438,435 (-)NCBI
Celera1666,776,909 - 66,863,441 (-)NCBICelera
Cytogenetic Map16q12.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
1. Ackermann MA, etal., J Cell Sci. 2011 Nov 1;124(Pt 21):3619-30. Epub 2011 Nov 1.
2. Birkenmeier CS, etal., Hematol J. 2003;4(6):445-9.
3. Eber SW, etal., Nat Genet. 1996 Jun;13(2):214-8.
4. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. GOA data from the GO Consortium
6. Harada K, etal., J Neurochem. 1997 Jul;69(1):371-6.
7. Huang H, etal., G3 (Bethesda). 2013 Oct 3;3(10):1687-95. doi: 10.1534/g3.113.007013.
8. Hughes MR, etal., Exp Hematol. 2011 Mar;39(3):305-20, 320.e1-2. doi: 10.1016/j.exphem.2010.12.009. Epub 2010 Dec 28.
9. Kontrogianni-Konstantopoulos A, etal., FASEB J. 2006 Oct;20(12):2102-11.
10. Kontrogianni-Konstantopoulos A, etal., Mol Biol Cell 2003 Mar;14(3):1138-48.
11. Kordeli E, etal., J Cell Biol. 1990 Apr;110(4):1341-52.
12. Kordeli E, etal., J Cell Sci 1998 Aug;111 ( Pt 15):2197-207.
13. MGD data from the GO Consortium
14. Morgans CW and Kopito RR, J Cell Sci. 1993 Aug;105 ( Pt 4):1137-42.
15. Nakanishi H, etal., Int J Hematol. 2001 Jan;73(1):54-63.
16. OMIM Disease Annotation Pipeline
17. Randon J, etal., Br J Haematol. 1997 Mar;96(3):500-6.
18. Rank G, etal., Blood. 2009 Apr 2;113(14):3352-62. doi: 10.1182/blood-2008-08-172841. Epub 2009 Jan 28.
19. RGD automated data pipeline
20. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
21. RGD automated import pipeline for gene-chemical interactions
22. RGD comprehensive gene curation
23. Yoshida K and Harada K, J Biochem (Tokyo). 1997 Aug;122(2):279-85.
24. Yuki KE, etal., PLoS One. 2013;8(2):e55331. doi: 10.1371/journal.pone.0055331. Epub 2013 Feb 4.
25. Zhou D, etal., J Cell Biol. 1997 Feb 10;136(3):621-31.
Additional References at PubMed
PMID:379653   PMID:658175   PMID:2139228   PMID:6234993   PMID:7492791   PMID:8159688   PMID:8889548   PMID:12354383   PMID:18723693   PMID:18768923   PMID:19002483   PMID:21177872  
PMID:21700703   PMID:22416964   PMID:26405035  


Genomics

Comparative Map Data
Ank1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21668,876,294 - 69,054,812 (-)NCBI
Rnor_6.0 Ensembl1673,681,422 - 73,827,488 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01673,681,422 - 73,912,605 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01673,397,821 - 73,459,822 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01673,314,002 - 73,331,197 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41673,333,564 - 73,437,926 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11673,333,832 - 73,438,435 (-)NCBI
Celera1666,776,909 - 66,863,441 (-)NCBICelera
Cytogenetic Map16q12.5NCBI
ANK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl841,653,220 - 41,896,762 (-)EnsemblGRCh38hg38GRCh38
GRCh38841,653,225 - 41,896,741 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37841,510,744 - 41,754,259 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh37841,510,744 - 41,754,280 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36841,629,901 - 41,774,297 (-)NCBINCBI36hg18NCBI36
Build 34841,632,000 - 41,641,949NCBI
Celera840,459,268 - 40,702,528 (-)NCBI
Cytogenetic Map8p11.21NCBI
HuRef840,038,471 - 40,281,660 (-)NCBIHuRef
CHM1_1841,558,937 - 41,802,421 (-)NCBICHM1_1
Ank1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39823,464,852 - 23,640,517 (+)NCBIGRCm39mm39
GRCm38822,974,836 - 23,150,501 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl822,974,844 - 23,150,497 (+)EnsemblGRCm38mm10GRCm38
MGSCv37824,085,354 - 24,260,968 (+)NCBIGRCm37mm9NCBIm37
MGSCv36824,523,820 - 24,616,041 (+)NCBImm8
Celera824,465,487 - 24,646,749 (+)NCBICelera
Cytogenetic Map8A2NCBI
cM Map811.42NCBI
Ank1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555361,049,407 - 1,237,943 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555361,049,325 - 1,237,943 (+)NCBIChiLan1.0ChiLan1.0
ANK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1838,346,503 - 38,588,620 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl838,346,503 - 38,588,549 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0840,897,879 - 41,140,290 (-)NCBIMhudiblu_PPA_v0panPan3
ANK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1623,766,193 - 23,964,226 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11623,858,299 - 23,966,181 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Ank1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936785738,323 - 944,734 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ANK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1710,763,876 - 10,985,191 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11710,752,258 - 10,985,129 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21712,184,513 - 12,419,119 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ANK1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1839,627,766 - 39,871,329 (-)NCBI
ChlSab1.1 Ensembl839,626,981 - 39,871,151 (-)Ensembl
Ank1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247801,429,415 - 1,619,010 (+)NCBI

Position Markers
D16Rat56  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01673,796,479 - 73,796,715NCBIRnor6.0
Rnor_5.01673,428,945 - 73,429,181UniSTSRnor5.0
RGSC_v3.41673,406,840 - 73,407,077RGDRGSC3.4
RGSC_v3.41673,406,841 - 73,407,077UniSTSRGSC3.4
RGSC_v3.11673,407,019 - 73,407,477RGD
Celera1666,832,820 - 66,833,048UniSTS
SHRSP x BN Map1636.28UniSTS
SHRSP x BN Map1636.28RGD
Cytogenetic Map16q12.5UniSTS
RH141704  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01673,674,719 - 73,674,918NCBIRnor6.0
Rnor_5.01673,306,846 - 73,307,045UniSTSRnor5.0
RGSC_v3.41673,335,789 - 73,335,988UniSTSRGSC3.4
Celera1666,769,840 - 66,770,039UniSTS
RH 3.4 Map16635.2UniSTS
Cytogenetic Map16q12.5UniSTS
BI276346  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01673,788,574 - 73,788,731NCBIRnor6.0
Rnor_5.01673,421,040 - 73,421,197UniSTSRnor5.0
RGSC_v3.41673,398,935 - 73,399,092UniSTSRGSC3.4
Celera1666,824,919 - 66,825,076UniSTS
Cytogenetic Map16q12.5UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)16109005486162972Rat
70215Niddm29Non-insulin dependent diabetes mellitus QTL 293.54blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)162075555680316424Rat
1578768Stresp22Stress response QTL 222.8thymus mass (VT:0004954)thymus wet weight (CMO:0000855)163900002184000021Rat
2300163Bmd64Bone mineral density QTL 645.30.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)164151271086512710Rat
2293690Bss45Bone structure and strength QTL 455.130.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)164151271086512710Rat
7205510Activ5Activity QTL 53.780.00028locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)164655818890668790Rat
7411648Foco22Food consumption QTL 22150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)165781635790668790Rat
8694429Bw164Body weight QTL 16450.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)165781635790668790Rat
8694364Abfw7Abdominal fat weight QTL 712.220.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)165781635790668790Rat
631525Pia14Pristane induced arthritis QTL 144.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)165928577589248943Rat
1298527Arunc2Aerobic running capacity QTL 22.9exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)167321963880115794Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:58
Count of miRNA genes:55
Interacting mature miRNAs:56
Transcripts:ENSRNOT00000064070
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 38 22 22 11 22 8 11 52 11 8
Low 5 15 4 7 4 22 26 25 11
Below cutoff 3 19 14 1 14 9 5

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001107322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094562 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094563 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094565 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094566 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094568 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094570 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094571 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094577 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094579 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094581 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094583 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094584 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094585 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005494624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473970 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000283 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000064070   ⟹   ENSRNOP00000062056
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1673,681,422 - 73,827,488 (-)Ensembl
RefSeq Acc Id: NM_001107322   ⟹   NP_001100792
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21668,885,524 - 68,969,002 (-)NCBI
Rnor_6.01673,681,422 - 73,827,488 (-)NCBI
Rnor_5.01673,314,002 - 73,331,197 (-)NCBI
Rnor_5.01673,397,821 - 73,459,822 (-)NCBI
RGSC_v3.41673,333,564 - 73,437,926 (-)RGD
Celera1666,776,909 - 66,863,441 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008771356   ⟹   XP_008769578
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01673,764,153 - 73,851,427 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008771357   ⟹   XP_008769579
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01673,764,153 - 73,851,427 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008771358   ⟹   XP_008769580
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01673,764,153 - 73,828,802 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008771359   ⟹   XP_008769581
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01673,764,153 - 73,912,605 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600148   ⟹   XP_017455637
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01673,764,153 - 73,912,604 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039094562   ⟹   XP_038950490
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21668,876,294 - 68,994,307 (-)NCBI
RefSeq Acc Id: XM_039094563   ⟹   XP_038950491
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21668,876,294 - 68,994,307 (-)NCBI
RefSeq Acc Id: XM_039094564   ⟹   XP_038950492
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21668,876,294 - 68,994,307 (-)NCBI
RefSeq Acc Id: XM_039094565   ⟹   XP_038950493
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21668,876,294 - 68,994,307 (-)NCBI
RefSeq Acc Id: XM_039094566   ⟹   XP_038950494
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21668,876,294 - 68,994,307 (-)NCBI
RefSeq Acc Id: XM_039094568   ⟹   XP_038950496
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21668,876,294 - 68,994,307 (-)NCBI
RefSeq Acc Id: XM_039094569   ⟹   XP_038950497
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21668,876,294 - 68,994,307 (-)NCBI
RefSeq Acc Id: XM_039094570   ⟹   XP_038950498
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21668,876,294 - 68,994,307 (-)NCBI
RefSeq Acc Id: XM_039094571   ⟹   XP_038950499
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21668,876,296 - 69,054,812 (-)NCBI
RefSeq Acc Id: XM_039094572   ⟹   XP_038950500
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21668,876,294 - 68,994,307 (-)NCBI
RefSeq Acc Id: XM_039094573   ⟹   XP_038950501
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21668,876,294 - 68,994,307 (-)NCBI
RefSeq Acc Id: XM_039094574   ⟹   XP_038950502
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21668,876,294 - 68,994,307 (-)NCBI
RefSeq Acc Id: XM_039094575   ⟹   XP_038950503
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21668,876,296 - 69,054,812 (-)NCBI
RefSeq Acc Id: XM_039094576   ⟹   XP_038950504
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21668,876,294 - 68,969,145 (-)NCBI
RefSeq Acc Id: XM_039094577   ⟹   XP_038950505
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21668,876,296 - 69,054,812 (-)NCBI
RefSeq Acc Id: XM_039094578   ⟹   XP_038950506
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21668,876,294 - 68,969,140 (-)NCBI
RefSeq Acc Id: XM_039094579   ⟹   XP_038950507
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21668,876,294 - 68,969,142 (-)NCBI
RefSeq Acc Id: XM_039094580   ⟹   XP_038950508
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21668,876,294 - 68,969,142 (-)NCBI
RefSeq Acc Id: XM_039094581   ⟹   XP_038950509
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21668,876,294 - 68,994,307 (-)NCBI
RefSeq Acc Id: XM_039094582   ⟹   XP_038950510
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21668,876,294 - 68,994,307 (-)NCBI
RefSeq Acc Id: XM_039094583   ⟹   XP_038950511
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21668,876,296 - 69,054,812 (-)NCBI
RefSeq Acc Id: XM_039094584   ⟹   XP_038950512
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21668,876,294 - 68,888,455 (-)NCBI
RefSeq Acc Id: XM_039094585   ⟹   XP_038950513
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21668,876,294 - 68,888,448 (-)NCBI
RefSeq Acc Id: XR_005494624
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21668,894,492 - 68,994,307 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001100792   ⟸   NM_001107322
- UniProtKB: D3Z9Z0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008769581   ⟸   XM_008771359
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_008769578   ⟸   XM_008771356
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008769579   ⟸   XM_008771357
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008769580   ⟸   XM_008771358
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_017455637   ⟸   XM_017600148
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: ENSRNOP00000062056   ⟸   ENSRNOT00000064070
RefSeq Acc Id: XP_038950510   ⟸   XM_039094582
- Peptide Label: isoform X20
RefSeq Acc Id: XP_038950502   ⟸   XM_039094574
- Peptide Label: isoform X12
RefSeq Acc Id: XP_038950498   ⟸   XM_039094570
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038950497   ⟸   XM_039094569
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038950491   ⟸   XM_039094563
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038950509   ⟸   XM_039094581
- Peptide Label: isoform X19
RefSeq Acc Id: XP_038950501   ⟸   XM_039094573
- Peptide Label: isoform X11
RefSeq Acc Id: XP_038950496   ⟸   XM_039094568
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038950494   ⟸   XM_039094566
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038950500   ⟸   XM_039094572
- Peptide Label: isoform X10
RefSeq Acc Id: XP_038950493   ⟸   XM_039094565
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038950492   ⟸   XM_039094564
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038950490   ⟸   XM_039094562
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038950504   ⟸   XM_039094576
- Peptide Label: isoform X14
RefSeq Acc Id: XP_038950508   ⟸   XM_039094580
- Peptide Label: isoform X18
RefSeq Acc Id: XP_038950507   ⟸   XM_039094579
- Peptide Label: isoform X17
RefSeq Acc Id: XP_038950506   ⟸   XM_039094578
- Peptide Label: isoform X16
RefSeq Acc Id: XP_038950512   ⟸   XM_039094584
- Peptide Label: isoform X22
RefSeq Acc Id: XP_038950513   ⟸   XM_039094585
- Peptide Label: isoform X23
RefSeq Acc Id: XP_038950511   ⟸   XM_039094583
- Peptide Label: isoform X21
RefSeq Acc Id: XP_038950505   ⟸   XM_039094577
- Peptide Label: isoform X15
RefSeq Acc Id: XP_038950503   ⟸   XM_039094575
- Peptide Label: isoform X13
RefSeq Acc Id: XP_038950499   ⟸   XM_039094571
- Peptide Label: isoform X9
Protein Domains
ANK_REP_REGION   ZU5

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Damaging Variants


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
16 73765771 73765772 G A snv F344/NRrrc (MCW), MR/N (MCW), FHL/EurMcwi (RGD), WAG/Rij (RGD), FHH/EurMcwi (RGD), LE/Stm (RGD), F344/NCrl (RGD)


Assembly: RGSC_v3.4

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
16 73376133 73376134 G A snv FHH/EurMcwi (MDC), F344/NHsd (ICAHN), LE/Stm (KNAW), MR/N (KNAW), FHH/EurMcwi (MCW), FHL/EurMcwi (MCW), F344/NCrl (ICL), LE/Stm (ICL), FHH/EurMcwi (ICL), FHL/EurMcwi (ICL), WAG/Rij (ICL), HCR/1Mco (UMich), LCR/1Mco (UMich), HCR/2Mco (UMich), LCR/2Mco (UMich), F344/NRrrc (KNAW)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309620 AgrOrtholog
Ensembl Genes ENSRNOG00000018241 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000062056 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000064070 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.20 UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_dom UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
  Ankyrin_UPA UniProtKB/TrEMBL
  ZU5 UniProtKB/TrEMBL
KEGG Report rno:306570 UniProtKB/TrEMBL
NCBI Gene 306570 ENTREZGENE
Pfam Ank UniProtKB/TrEMBL
  Ank_2 UniProtKB/TrEMBL
  Ank_3 UniProtKB/TrEMBL
  UPA_2 UniProtKB/TrEMBL
  ZU5 UniProtKB/TrEMBL
PhenoGen Ank1 PhenoGen
PRINTS ANKYRIN UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
  ZU5 UniProtKB/TrEMBL
SMART ANK UniProtKB/TrEMBL
  ZU5 UniProtKB/TrEMBL
Superfamily-SCOP ANK UniProtKB/TrEMBL
UniProt D3Z9Z0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-25 Ank1  ankyrin 1  Ank1  ankyrin 1, erythrocytic  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-26 Ank1  ankyrin 1, erythrocytic  Ank1  ankyrin 1, erythroid  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Ank1  ankyrin 1, erythroid  Ank1_predicted  ankyrin 1, erythroid (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Ank1_predicted  ankyrin 1, erythroid (predicted)      Symbol and Name status set to approved 70820 APPROVED