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Gene: Gadd45a (growth arrest and DNA-damage-inducible, alpha) Rattus norvegicus
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Symbol: Gadd45a
Name: growth arrest and DNA-damage-inducible, alpha
Description: Predicted to have several functions, including promoter-specific chromatin binding activity; protein N-terminus binding activity; and protein dimerization activity. Involved in G2/M transition of mitotic cell cycle. Predicted to localize to cytoplasm and nuclear speck. Orthologous to human GADD45A (growth arrest and DNA damage inducible alpha); PARTICIPATES IN p38 MAPK signaling pathway; cell cycle pathway, mitotic; mitogen activated protein kinase signaling pathway; INTERACTS WITH (+)-alpha-tocopherol; (+)-schisandrin B; (S)-colchicine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: DDIT-1; Ddit1; DNA damage-inducible transcript 1 protein; DNA-damage-inducible transcript 1; Gadd45; growth arrest and DNA damage-inducible protein GADD45 alpha; growth arrest and DNA-damage-inducible 45 alpha; Growth arrest and DNA-damage-inducible protein; growth arrest and DNA-damage-inducible protein GADD45 alpha
Orthologs:
Homo sapiens (human) : GADD45A (growth arrest and DNA damage inducible alpha)  HGNC  Alliance
Mus musculus (house mouse) : Gadd45a (growth arrest and DNA-damage-inducible 45 alpha)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gadd45a (growth arrest and DNA damage inducible alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : GADD45A (growth arrest and DNA damage inducible alpha)
Canis lupus familiaris (dog) : GADD45A (growth arrest and DNA damage inducible alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gadd45a (growth arrest and DNA damage inducible alpha)
Sus scrofa (pig) : GADD45A (growth arrest and DNA damage inducible alpha)
Chlorocebus sabaeus (African green monkey) : GADD45A (growth arrest and DNA damage inducible alpha)
Heterocephalus glaber (naked mole-rat) : Gadd45a (growth arrest and DNA damage inducible alpha)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0497,782,512 - 97,784,814 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl497,782,512 - 97,784,842 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04162,568,472 - 162,570,774 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4496,649,941 - 96,652,243 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1496,894,423 - 96,896,724 (-)NCBI
Celera490,851,517 - 90,853,819 (-)NCBICelera
Cytogenetic Map4q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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Alliance Gene
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JBrowse: rn5 rn6
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RGD Object Information
RGD ID: 2654
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-03-31
Status: ACTIVE



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