Imported Disease Annotations - OMIMObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Mcm8 | Rat | primary ovarian insufficiency 10 | | ISO | MCM8 (Homo sapiens) | 7240710 | | OMIM | | |
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Imported Disease Annotations - OMIMObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Mcm8 | Rat | primary ovarian insufficiency 10 | | ISO | MCM8 (Homo sapiens) | 7240710 | | OMIM | | |
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# | Reference Title | Reference Citation |
1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
2. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
PMID:22771115 | PMID:22771120 | PMID:23401855 | PMID:26215093 | PMID:26300262 |
Mcm8 (Rattus norvegicus - Norway rat) |
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MCM8 (Homo sapiens - human) |
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Mcm8 (Mus musculus - house mouse) |
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Mcm8 (Chinchilla lanigera - long-tailed chinchilla) |
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MCM8 (Pan paniscus - bonobo/pygmy chimpanzee) |
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MCM8 (Canis lupus familiaris - dog) |
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Mcm8 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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MCM8 (Sus scrofa - pig) |
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MCM8 (Chlorocebus sabaeus - green monkey) |
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Mcm8 (Heterocephalus glaber - naked mole-rat) |
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The detailed report is available here: | Full Report | CSV | TAB | Printer | ||||
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
BF389667 |
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BF412056 |
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alimentary part of gastrointestinal system
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appendage
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circulatory system
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ectoderm
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endocrine system
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endoderm
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exocrine system
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hemolymphoid system
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hepatobiliary system
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integumental system
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mesenchyme
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mesoderm
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nervous system
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renal system
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reproductive system
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respiratory system
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9 | 11 | 49 | 113 | 91 | 90 | 59 | 25 | 59 | 6 | 218 | 97 | 93 | 45 | 60 | 31 |
RefSeq Transcripts | NM_001106514 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
NM_001431517 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
NM_001431518 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
NR_197230 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_006235074 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039104589 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039104590 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | CH473949 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
JAXUCZ010000003 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Ensembl Acc Id: | ENSRNOT00000028898 ⟹ ENSRNOP00000028898 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Ensembl Acc Id: | ENSRNOT00000106451 ⟹ ENSRNOP00000076589 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | NM_001106514 ⟹ NP_001099984 | ||||||||||||||||||||||||||||
RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006235074 ⟹ XP_006235136 | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_039104589 ⟹ XP_038960517 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XM_039104590 ⟹ XP_038960518 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Protein RefSeqs | NP_001099984 | (Get FASTA) | NCBI Sequence Viewer |
NP_001418446 | (Get FASTA) | NCBI Sequence Viewer | |
NP_001418447 | (Get FASTA) | NCBI Sequence Viewer | |
XP_006235136 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038960517 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038960518 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | D3ZVK1 | (Get FASTA) | NCBI Sequence Viewer |
EDL80275 | (Get FASTA) | NCBI Sequence Viewer | |
Ensembl Protein | ENSRNOP00000028898.5 | ||
ENSRNOP00000076589.1 | |||
ENSRNOP00055007369 |
RefSeq Acc Id: | NP_001099984 ⟸ NM_001106514 |
- UniProtKB: | D3ZVK1 (UniProtKB/Swiss-Prot), A0A8I5XV71 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006235136 ⟸ XM_006235074 |
- Peptide Label: | isoform X1 |
- Sequence: |
Ensembl Acc Id: | ENSRNOP00000028898 ⟸ ENSRNOT00000028898 |
RefSeq Acc Id: | XP_038960517 ⟸ XM_039104589 |
- Peptide Label: | isoform X2 |
RefSeq Acc Id: | XP_038960518 ⟸ XM_039104590 |
- Peptide Label: | isoform X3 |
Ensembl Acc Id: | ENSRNOP00000076589 ⟸ ENSRNOT00000106451 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-D3ZVK1-F1-model_v2 | AlphaFold | D3ZVK1 | 1-830 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
Database | Acc Id | Source(s) |
AGR Gene | RGD:1305218 | AgrOrtholog |
BioCyc Gene | G2FUF-47763 | BioCyc |
Ensembl Genes | ENSRNOG00000021272 | Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
ENSRNOG00055005905 | UniProtKB/Swiss-Prot | |
Ensembl Transcript | ENSRNOT00000028898.6 | UniProtKB/Swiss-Prot |
ENSRNOT00000106451.1 | UniProtKB/TrEMBL | |
ENSRNOT00055009556 | UniProtKB/Swiss-Prot | |
Gene3D-CATH | 2.20.28.10 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
2.40.50.140 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
3.40.50.300 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
InterPro | AAA+_ATPase | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
MCM | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
MCM_dom | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
MCM_lid | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
MCM_OB | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
NA-bd_OB-fold | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
P-loop_NTPase | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
KEGG Report | rno:296178 | UniProtKB/Swiss-Prot |
NCBI Gene | 296178 | ENTREZGENE |
PANTHER | DNA HELICASE MCM8 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PTHR11630 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Pfam | MCM | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
MCM_lid | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
MCM_OB | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PhenoGen | Mcm8 | PhenoGen |
PRINTS | MCMFAMILY | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PROSITE | MCM_2 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
RatGTEx | ENSRNOG00000021272 | RatGTEx |
ENSRNOG00055005905 | RatGTEx | |
SMART | AAA | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
MCM | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Superfamily-SCOP | SSF50249 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
SSF52540 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
UniProt | A0A8I5XV71 | ENTREZGENE, UniProtKB/TrEMBL |
D3ZVK1 | ENTREZGENE, UniProtKB/Swiss-Prot |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2015-09-16 | Mcm8 | minichromosome maintenance 8 homologous recombination repair factor | Mcm8 | minichromosome maintenance complex component 8 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2008-10-24 | Mcm8 | minichromosome maintenance complex component 8 | Mcm8 | minichromosome maintenance deficient 8 (S. cerevisiae) | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2008-04-30 | Mcm8 | minichromosome maintenance deficient 8 (S. cerevisiae) | Mcm8_predicted | minichromosome maintenance deficient 8 (S. cerevisiae) (predicted) | 'predicted' is removed | 2292626 | APPROVED |
2005-01-12 | Mcm8_predicted | minichromosome maintenance deficient 8 (S. cerevisiae) (predicted) | Symbol and Name status set to approved | 70820 | APPROVED |