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GENE - TERM ANNOTATION REPORT

RGD ID: 1305218
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mcm8
Name: minichromosome maintenance 8 homologous recombination repair factor
Acc ID: GO:0000724
Term: double-strand break repair via homologous recombination
Definition: The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.
Definition Source(s): GOC:elh, PMID:10357855
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mcm8involved_inISOMCM8 (Homo sapiens)1624291RGD PMID:23401855

PMID:23401855
Mcm8involved_inISOMcm8 (Mus musculus)1624291RGD MGI:5437561 PMID:22771120

MGI:5437561 PMID:22771120
Mcm8involved_inIBAMGI:1913884 or PANTHER:PTN000179849 or UniProtKB:I0IUP3 or UniProtKB:Q9UJA31600115GO_CentralGO_REF:0000033

GO_REF:0000033
Mcm8involved_inIEAPANTHER:PTHR11630:SF471600115TreeGrafterGO_REF:0000118

GO_REF:0000118
Mcm8involved_inISSUniProtKB:Q9CWV11600115UniProtGO_REF:0000024

GO_REF:0000024
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