(+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of PHGDH mRNA] CTD PMID:31150632 (R)-adrenaline increases expression EXP 6480464 Epinephrine results in increased expression of PHGDH mRNA CTD PMID:12423672 (S)-nicotine increases expression ISO PHGDH (Homo sapiens) 6480464 Nicotine results in increased expression of PHGDH mRNA CTD PMID:23825647 1,2-dichloroethane increases expression ISO Phgdh (Mus musculus) 6480464 ethylene dichloride results in increased expression of PHGDH mRNA CTD PMID:28960355 1,2-dimethylhydrazine increases expression ISO Phgdh (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in increased expression of PHGDH mRNA CTD PMID:22206623 1,2-dimethylhydrazine multiple interactions ISO Phgdh (Mus musculus) 6480464 Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of PHGDH mRNA] CTD PMID:22206623 1-bromopropane increases expression EXP 6480464 1-bromopropane results in increased expression of PHGDH protein CTD PMID:21925529 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of PHGDH mRNA CTD PMID:30723492 17alpha-ethynylestradiol increases expression ISO Phgdh (Mus musculus) 6480464 Ethinyl Estradiol results in increased expression of PHGDH mRNA CTD PMID:16174780 more ... 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of PHGDH mRNA CTD PMID:16174780 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of PHGDH mRNA CTD PMID:17557909 17alpha-ethynylestradiol multiple interactions ISO Phgdh (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PHGDH mRNA CTD PMID:17942748 17beta-estradiol affects expression ISO PHGDH (Homo sapiens) 6480464 Estradiol affects the expression of PHGDH mRNA CTD PMID:22574217 17beta-estradiol affects expression EXP 6480464 Estradiol affects the expression of PHGDH mRNA CTD PMID:32145629 17beta-estradiol multiple interactions ISO PHGDH (Homo sapiens) 6480464 [Estradiol co-treated with TGFB1 protein] results in decreased expression of PHGDH mRNA CTD PMID:30165855 17beta-estradiol decreases expression ISO Phgdh (Mus musculus) 6480464 Estradiol results in decreased expression of PHGDH mRNA CTD PMID:19484750 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one decreases expression ISO PHGDH (Homo sapiens) 6480464 Metribolone results in decreased expression of PHGDH protein CTD PMID:17152098 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one increases expression ISO PHGDH (Homo sapiens) 6480464 Metribolone results in increased expression of PHGDH protein CTD PMID:17152098 17beta-hydroxy-5alpha-androstan-3-one increases expression ISO Phgdh (Mus musculus) 6480464 Dihydrotestosterone results in increased expression of PHGDH mRNA CTD PMID:17023530 2,2',4,4'-Tetrabromodiphenyl ether decreases expression ISO PHGDH (Homo sapiens) 6480464 2 more ... CTD PMID:31675489 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Phgdh (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PHGDH mRNA and Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to PHGDH promoter] CTD PMID:17942748 and PMID:19654925 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of PHGDH mRNA CTD PMID:20959002 and PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Phgdh (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of PHGDH mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO PHGDH (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in decreased expression of PHGDH mRNA CTD PMID:20106945 and PMID:21632981 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Phgdh (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of PHGDH mRNA CTD PMID:19770486 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Phgdh (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of PHGDH mRNA CTD PMID:17942748 and PMID:19933214 2,4,6-tribromophenol decreases expression ISO PHGDH (Homo sapiens) 6480464 2 more ... CTD PMID:31675489 2,4-D multiple interactions ISO Phgdh (Mus musculus) 6480464 [lard co-treated with Cholesterol more ... CTD PMID:37567420 2,4-dibromophenyl 2,4,5-tribromophenyl ether increases expression ISO Phgdh (Mus musculus) 6480464 2 more ... CTD PMID:18550172 2,4-dibromophenyl 2,4,5-tribromophenyl ether increases expression EXP 6480464 2 more ... CTD PMID:19954255 2-amino-14,16-dimethyloctadecan-3-ol decreases expression ISO PHGDH (Homo sapiens) 6480464 2-amino-14 and 16-dimethyloctadecan-3-ol results in decreased expression of PHGDH protein CTD PMID:32044396 2-methylcholine affects expression ISO PHGDH (Homo sapiens) 6480464 beta-methylcholine affects the expression of PHGDH mRNA CTD PMID:21179406 2-nitrofluorene decreases expression EXP 6480464 2-nitrofluorene results in decreased expression of PHGDH mRNA CTD PMID:15890375 3,3',4,4',5-pentachlorobiphenyl increases expression EXP 6480464 3 more ... CTD PMID:20959002 3,3',5,5'-tetrabromobisphenol A decreases expression ISO PHGDH (Homo sapiens) 6480464 tetrabromobisphenol A results in decreased expression of PHGDH protein CTD PMID:31675489 3,4-methylenedioxymethamphetamine increases expression ISO Phgdh (Mus musculus) 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of PHGDH mRNA CTD PMID:20188158 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of PHGDH mRNA CTD PMID:28522335 3H-1,2-dithiole-3-thione increases expression EXP 6480464 1 and 2-dithiol-3-thione results in increased expression of PHGDH mRNA CTD PMID:19162173 4,4'-diaminodiphenylmethane increases expression EXP 6480464 4 and 4'-diaminodiphenylmethane results in increased expression of PHGDH mRNA CTD PMID:30723492 4,4'-sulfonyldiphenol affects expression ISO PHGDH (Homo sapiens) 6480464 bisphenol S affects the expression of PHGDH protein CTD PMID:31945527 4,4'-sulfonyldiphenol affects methylation ISO Phgdh (Mus musculus) 6480464 bisphenol S affects the methylation of PHGDH gene CTD PMID:31683443 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases expression EXP 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PHGDH mRNA CTD PMID:15890375 4-hydroxynon-2-enal affects binding ISO PHGDH (Homo sapiens) 6480464 PHGDH protein binds to 4-hydroxy-2-nonenal CTD PMID:20043646 4-hydroxyphenyl retinamide decreases expression ISO Phgdh (Mus musculus) 6480464 Fenretinide results in decreased expression of PHGDH mRNA CTD PMID:28973697 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of PHGDH mRNA CTD PMID:30047161 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of PHGDH mRNA CTD PMID:36843608 6alpha-methylprednisolone decreases expression ISO PHGDH (Homo sapiens) 6480464 Methylprednisolone results in decreased expression of PHGDH mRNA CTD PMID:19192274 acetamide increases expression EXP 6480464 acetamide results in increased expression of PHGDH mRNA CTD PMID:31881176 acrolein multiple interactions ISO PHGDH (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of PHGDH mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of PHGDH mRNA CTD PMID:32699268 acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of PHGDH mRNA CTD PMID:28959563 acrylamide increases expression ISO PHGDH (Homo sapiens) 6480464 Acrylamide results in increased expression of PHGDH mRNA CTD PMID:32763439 aflatoxin B1 affects expression ISO PHGDH (Homo sapiens) 6480464 Aflatoxin B1 affects the expression of PHGDH protein CTD PMID:20106945 aflatoxin B1 decreases expression ISO PHGDH (Homo sapiens) 6480464 Aflatoxin B1 results in decreased expression of PHGDH mRNA CTD PMID:21632981 more ... aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of PHGDH mRNA CTD PMID:15890375 more ... aflatoxin B1 decreases expression ISO Phgdh (Mus musculus) 6480464 Aflatoxin B1 results in decreased expression of PHGDH mRNA CTD PMID:19770486 aldehydo-D-glucose multiple interactions ISO Phgdh (Mus musculus) 6480464 [lard co-treated with Cholesterol more ... CTD PMID:37567420 all-trans-retinoic acid decreases expression ISO PHGDH (Homo sapiens) 6480464 Tretinoin results in decreased expression of PHGDH mRNA CTD PMID:33167477 alpha-pinene multiple interactions ISO PHGDH (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of PHGDH mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of PHGDH mRNA CTD PMID:32699268 amitrole increases expression EXP 6480464 Amitrole results in increased expression of PHGDH mRNA CTD PMID:30047161 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of PHGDH mRNA CTD PMID:16483693 antimycin A increases expression ISO PHGDH (Homo sapiens) 6480464 Antimycin A results in increased expression of PHGDH mRNA CTD PMID:33512557 aristolochic acid A decreases expression ISO PHGDH (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of PHGDH mRNA CTD PMID:33212167 arsane increases ubiquitination ISO PHGDH (Homo sapiens) 6480464 Arsenic results in increased ubiquitination of PHGDH protein CTD PMID:35994080 arsenic atom increases ubiquitination ISO PHGDH (Homo sapiens) 6480464 Arsenic results in increased ubiquitination of PHGDH protein CTD PMID:35994080 arsenite(3-) multiple interactions ISO PHGDH (Homo sapiens) 6480464 arsenite promotes the reaction [G3BP1 protein binds to PHGDH protein] CTD PMID:32406909 arsenous acid multiple interactions ISO PHGDH (Homo sapiens) 6480464 Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PHGDH protein] CTD PMID:26598702 azathioprine decreases expression ISO PHGDH (Homo sapiens) 6480464 Azathioprine results in decreased expression of PHGDH mRNA CTD PMID:19192274 azoxystrobin increases expression ISO PHGDH (Homo sapiens) 6480464 azoxystrobin results in increased expression of PHGDH mRNA CTD PMID:33512557 beauvericin multiple interactions ISO PHGDH (Homo sapiens) 6480464 [beauvericin co-treated with enniatins] results in increased expression of PHGDH protein CTD PMID:32407736 benzatropine decreases expression ISO PHGDH (Homo sapiens) 6480464 Benztropine results in decreased expression of PHGDH protein CTD PMID:34122009 benzo[a]pyrene decreases expression ISO Phgdh (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of PHGDH mRNA CTD PMID:19770486 and PMID:22610609 benzo[a]pyrene affects methylation ISO PHGDH (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of PHGDH promoter CTD PMID:27901495 benzo[a]pyrene decreases expression ISO PHGDH (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of PHGDH mRNA and Benzo(a)pyrene results in decreased expression of PHGDH protein CTD PMID:20106945 more ... benzo[a]pyrene multiple interactions ISO PHGDH (Homo sapiens) 6480464 [Soot co-treated with Benzo(a)pyrene] results in increased expression of PHGDH protein CTD PMID:24464499 beta-naphthoflavone increases expression ISO PHGDH (Homo sapiens) 6480464 beta-Naphthoflavone results in increased expression of PHGDH mRNA CTD PMID:32858204 bisphenol A decreases expression ISO PHGDH (Homo sapiens) 6480464 bisphenol A results in decreased expression of PHGDH mRNA and bisphenol A results in decreased expression of PHGDH protein CTD PMID:20678512 more ... bisphenol A decreases expression ISO Phgdh (Mus musculus) 6480464 bisphenol A results in decreased expression of PHGDH mRNA CTD PMID:35598803 bisphenol A increases expression ISO PHGDH (Homo sapiens) 6480464 bisphenol A results in increased expression of PHGDH mRNA and bisphenol A results in increased expression of PHGDH protein CTD PMID:29275510 and PMID:34186270 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of PHGDH mRNA CTD PMID:30816183 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of PHGDH mRNA CTD PMID:25181051 and PMID:32145629 Bisphenol B increases expression ISO PHGDH (Homo sapiens) 6480464 bisphenol B results in increased expression of PHGDH protein CTD PMID:34186270 bisphenol F increases expression ISO PHGDH (Homo sapiens) 6480464 bisphenol F results in increased expression of PHGDH protein CTD PMID:34186270 butanal increases expression ISO PHGDH (Homo sapiens) 6480464 butyraldehyde results in increased expression of PHGDH mRNA CTD PMID:26079696 cadmium atom multiple interactions ISO PHGDH (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PHGDH mRNA CTD PMID:35301059 cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of PHGDH protein CTD PMID:21699967 cadmium dichloride multiple interactions ISO PHGDH (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PHGDH mRNA CTD PMID:35301059 cadmium dichloride affects expression ISO PHGDH (Homo sapiens) 6480464 Cadmium Chloride affects the expression of PHGDH mRNA CTD PMID:25596134 calcium silicate increases expression ISO Phgdh (Mus musculus) 6480464 calcium silicate results in increased expression of PHGDH mRNA CTD PMID:29279043 cantharidin increases expression ISO Phgdh (Mus musculus) 6480464 Cantharidin results in increased expression of PHGDH mRNA CTD PMID:36907384 carbon nanotube decreases expression ISO Phgdh (Mus musculus) 6480464 Nanotubes and Carbon analog results in decreased expression of PHGDH mRNA CTD PMID:25554681 carnosic acid decreases expression ISO Phgdh (Mus musculus) 6480464 salvin results in decreased expression of PHGDH protein CTD PMID:35926579 CGP 52608 multiple interactions ISO PHGDH (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to PHGDH gene] CTD PMID:28238834 chloroacetaldehyde affects expression ISO PHGDH (Homo sapiens) 6480464 chloroacetaldehyde affects the expression of PHGDH mRNA CTD PMID:25596134 chloropicrin decreases expression ISO PHGDH (Homo sapiens) 6480464 chloropicrin results in decreased expression of PHGDH mRNA CTD PMID:26352163 choline multiple interactions ISO Phgdh (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of PHGDH mRNA CTD PMID:20938992 cidofovir anhydrous affects expression ISO PHGDH (Homo sapiens) 6480464 Cidofovir affects the expression of PHGDH mRNA CTD PMID:25596134 cisplatin multiple interactions ISO PHGDH (Homo sapiens) 6480464 Cisplatin promotes the reaction [Piroxicam results in decreased expression of PHGDH mRNA] CTD PMID:21858171 cisplatin decreases expression ISO PHGDH (Homo sapiens) 6480464 Cisplatin results in decreased expression of PHGDH protein CTD PMID:20540955 cisplatin increases expression ISO PHGDH (Homo sapiens) 6480464 Cisplatin results in increased expression of PHGDH mRNA CTD PMID:27594783 cisplatin decreases expression EXP 6480464 Cisplatin results in decreased expression of PHGDH mRNA CTD PMID:22023808 clobetasol increases expression ISO Phgdh (Mus musculus) 6480464 Clobetasol results in increased expression of PHGDH mRNA CTD PMID:27462272 clodronic acid decreases expression ISO PHGDH (Homo sapiens) 6480464 Clodronic Acid results in decreased expression of PHGDH mRNA CTD PMID:25596134 cobalt dichloride decreases expression ISO PHGDH (Homo sapiens) 6480464 cobaltous chloride results in decreased expression of PHGDH mRNA CTD PMID:19376846 copper atom multiple interactions ISO PHGDH (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in increased expression of PHGDH mRNA CTD PMID:30911355 and PMID:31162603 copper(0) multiple interactions ISO PHGDH (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in increased expression of PHGDH mRNA CTD PMID:30911355 and PMID:31162603 copper(II) sulfate increases expression ISO PHGDH (Homo sapiens) 6480464 Copper Sulfate results in increased expression of PHGDH mRNA CTD PMID:19549813 coumestrol increases expression ISO PHGDH (Homo sapiens) 6480464 Coumestrol results in increased expression of PHGDH mRNA CTD PMID:19167446 Cuprizon increases expression EXP 6480464 Cuprizone results in increased expression of PHGDH mRNA CTD PMID:27523638 cyclosporin A affects expression ISO Phgdh (Mus musculus) 6480464 Cyclosporine affects the expression of PHGDH mRNA CTD PMID:19770486 cyclosporin A increases expression ISO PHGDH (Homo sapiens) 6480464 Cyclosporine results in increased expression of PHGDH mRNA CTD PMID:20106945 more ... cyclosporin A increases expression EXP 6480464 Cyclosporine results in increased expression of PHGDH mRNA CTD PMID:25596134 cyclosporin A affects expression ISO PHGDH (Homo sapiens) 6480464 Cyclosporine affects the expression of PHGDH mRNA CTD PMID:25562108 D-glucose multiple interactions ISO Phgdh (Mus musculus) 6480464 [lard co-treated with Cholesterol more ... CTD PMID:37567420 decabromodiphenyl ether decreases expression ISO PHGDH (Homo sapiens) 6480464 decabromobiphenyl ether results in decreased expression of PHGDH protein CTD PMID:31675489 deguelin increases expression ISO PHGDH (Homo sapiens) 6480464 deguelin results in increased expression of PHGDH mRNA CTD PMID:33512557 deoxynivalenol decreases expression ISO PHGDH (Homo sapiens) 6480464 deoxynivalenol results in decreased expression of PHGDH mRNA CTD PMID:31863870 dexamethasone decreases expression ISO Phgdh (Mus musculus) 6480464 Dexamethasone results in decreased expression of PHGDH mRNA CTD PMID:22733784 dexamethasone decreases expression ISO PHGDH (Homo sapiens) 6480464 Dexamethasone results in decreased expression of PHGDH mRNA CTD PMID:25047013 diarsenic trioxide multiple interactions ISO PHGDH (Homo sapiens) 6480464 Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PHGDH protein] CTD PMID:26598702 dibenzofurans decreases expression ISO Phgdh (Mus musculus) 6480464 Dibenzofurans results in decreased expression of PHGDH mRNA CTD PMID:34254344 dibutyl phthalate decreases expression ISO Phgdh (Mus musculus) 6480464 Dibutyl Phthalate results in decreased expression of PHGDH mRNA CTD PMID:21266533 dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of PHGDH mRNA CTD PMID:17379624 dichloroacetic acid decreases expression ISO PHGDH (Homo sapiens) 6480464 Dichloroacetic Acid results in decreased expression of PHGDH mRNA CTD PMID:33405312 diethylstilbestrol increases expression EXP 6480464 Diethylstilbestrol results in increased expression of PHGDH mRNA CTD PMID:15890375 diethylstilbestrol increases expression ISO Phgdh (Mus musculus) 6480464 Diethylstilbestrol results in increased expression of PHGDH mRNA CTD PMID:14648872 dioxygen decreases expression ISO PHGDH (Homo sapiens) 6480464 Oxygen deficiency results in decreased expression of PHGDH mRNA CTD PMID:25596134 dobutamine increases expression EXP 6480464 Dobutamine results in increased expression of PHGDH mRNA CTD PMID:12423672 doxorubicin affects expression ISO PHGDH (Homo sapiens) 6480464 Doxorubicin affects the expression of PHGDH protein CTD PMID:29385562 doxorubicin decreases expression ISO PHGDH (Homo sapiens) 6480464 Doxorubicin results in decreased expression of PHGDH mRNA CTD PMID:29803840 endosulfan increases expression EXP 6480464 Endosulfan results in increased expression of PHGDH mRNA CTD PMID:29391264 enniatin multiple interactions ISO PHGDH (Homo sapiens) 6480464 [beauvericin co-treated with enniatins] results in increased expression of PHGDH protein CTD PMID:32407736 enzyme inhibitor multiple interactions ISO PHGDH (Homo sapiens) 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of PHGDH protein CTD PMID:23301498 enzyme inhibitor decreases activity EXP 6480464 Enzyme Inhibitors results in decreased activity of PHGDH protein CTD PMID:31108107 ethanol decreases expression EXP 6480464 Ethanol results in decreased expression of PHGDH mRNA CTD PMID:20655511 ethanol increases expression ISO Phgdh (Mus musculus) 6480464 Ethanol results in increased expression of PHGDH mRNA CTD PMID:30319688 ethanol increases expression ISO PHGDH (Homo sapiens) 6480464 Ethanol results in increased expression of PHGDH protein CTD PMID:20621659 etoposide affects response to substance ISO PHGDH (Homo sapiens) 6480464 PHGDH protein affects the susceptibility to Etoposide CTD PMID:16217747 fenamidone increases expression ISO Phgdh (Mus musculus) 6480464 fenamidone results in increased expression of PHGDH mRNA CTD PMID:27029645 fenofibrate increases expression EXP 6480464 Fenofibrate results in increased expression of PHGDH mRNA CTD PMID:25596134 fenofibrate increases expression ISO PHGDH (Homo sapiens) 6480464 Fenofibrate results in increased expression of PHGDH mRNA CTD PMID:25596134 fenpyroximate increases expression ISO PHGDH (Homo sapiens) 6480464 fenpyroximate results in increased expression of PHGDH mRNA CTD PMID:33512557 flutamide increases expression EXP 6480464 Flutamide results in increased expression of PHGDH mRNA CTD PMID:24136188 folic acid multiple interactions ISO Phgdh (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of PHGDH mRNA more ... CTD PMID:20938992 and PMID:22206623 FR900359 affects phosphorylation ISO PHGDH (Homo sapiens) 6480464 FR900359 affects the phosphorylation of PHGDH protein CTD PMID:37730182 fructose multiple interactions ISO Phgdh (Mus musculus) 6480464 [lard co-treated with Cholesterol more ... CTD PMID:37567420 furan increases methylation EXP 6480464 furan results in increased methylation of PHGDH gene CTD PMID:22079235 furan increases expression EXP 6480464 furan results in increased expression of PHGDH mRNA CTD PMID:25539665 and PMID:26194646 glafenine increases expression EXP 6480464 Glafenine results in increased expression of PHGDH mRNA CTD PMID:24136188 glucose multiple interactions ISO Phgdh (Mus musculus) 6480464 [lard co-treated with Cholesterol more ... CTD PMID:37567420 hyaluronic acid multiple interactions EXP 6480464 Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of PHGDH protein] CTD PMID:23178681 hydrogen peroxide multiple interactions EXP 6480464 Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of PHGDH protein] CTD PMID:23178681 hydrogen peroxide decreases expression EXP 6480464 Hydrogen Peroxide results in decreased expression of PHGDH protein CTD PMID:23178681 ifosfamide increases expression ISO PHGDH (Homo sapiens) 6480464 Ifosfamide results in increased expression of PHGDH mRNA CTD PMID:25596134 indole-3-methanol affects expression EXP 6480464 indole-3-carbinol affects the expression of PHGDH mRNA CTD PMID:21396975 indometacin increases expression EXP 6480464 Indomethacin results in increased expression of PHGDH mRNA CTD PMID:16184411 indometacin affects expression EXP 6480464 Indomethacin affects the expression of PHGDH mRNA CTD PMID:36868495 isotretinoin increases expression ISO PHGDH (Homo sapiens) 6480464 Isotretinoin results in increased expression of PHGDH mRNA CTD PMID:20436886 ivermectin decreases expression ISO PHGDH (Homo sapiens) 6480464 Ivermectin results in decreased expression of PHGDH protein CTD PMID:32959892 L-ascorbic acid decreases expression ISO PHGDH (Homo sapiens) 6480464 Ascorbic Acid results in decreased expression of PHGDH mRNA CTD PMID:19197388 L-methionine multiple interactions ISO Phgdh (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of PHGDH mRNA CTD PMID:20938992 lipopolysaccharide increases expression ISO Phgdh (Mus musculus) 6480464 Lipopolysaccharides results in increased expression of PHGDH mRNA CTD PMID:12057914 lucanthone decreases expression ISO PHGDH (Homo sapiens) 6480464 Lucanthone results in decreased expression of PHGDH mRNA CTD PMID:21148553 metformin increases expression EXP 6480464 Metformin results in increased expression of PHGDH mRNA CTD PMID:25596134 methamphetamine decreases expression EXP 6480464 Methamphetamine results in decreased expression of PHGDH protein CTD PMID:19826936 methapyrilene increases expression EXP 6480464 Methapyrilene results in increased expression of PHGDH mRNA CTD PMID:15890375 and PMID:22484513 methapyrilene decreases expression EXP 6480464 Methapyrilene results in decreased expression of PHGDH mRNA CTD PMID:30467583 methimazole increases expression EXP 6480464 Methimazole results in increased expression of PHGDH mRNA CTD PMID:30047161 methotrexate decreases expression ISO PHGDH (Homo sapiens) 6480464 Methotrexate results in decreased expression of PHGDH mRNA CTD PMID:19192274 mitoxantrone affects response to substance ISO PHGDH (Homo sapiens) 6480464 PHGDH protein affects the susceptibility to Mitoxantrone CTD PMID:16217747 N-methyl-4-phenylpyridinium increases expression ISO PHGDH (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium results in increased expression of PHGDH mRNA CTD PMID:24810058 N-methyl-4-phenylpyridinium increases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in increased expression of PHGDH mRNA CTD PMID:28801915 N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of PHGDH mRNA CTD PMID:19638242 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of PHGDH mRNA CTD PMID:28943392 N-nitrosodiethylamine increases expression ISO Phgdh (Mus musculus) 6480464 Diethylnitrosamine results in increased expression of PHGDH mRNA CTD PMID:24535843 N-nitrosodimethylamine increases expression EXP 6480464 Dimethylnitrosamine results in increased expression of PHGDH mRNA CTD PMID:15890375 nefazodone increases expression EXP 6480464 nefazodone results in increased expression of PHGDH mRNA CTD PMID:24136188 nicotine increases expression ISO PHGDH (Homo sapiens) 6480464 Nicotine results in increased expression of PHGDH mRNA CTD PMID:23825647 ochratoxin A decreases expression ISO PHGDH (Homo sapiens) 6480464 ochratoxin A results in decreased expression of PHGDH mRNA CTD PMID:30559759 ozone multiple interactions ISO PHGDH (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of PHGDH mRNA more ... CTD PMID:32699268 paclitaxel decreases expression EXP 6480464 Paclitaxel results in decreased expression of PHGDH protein CTD PMID:21118710 paracetamol affects expression ISO Phgdh (Mus musculus) 6480464 Acetaminophen affects the expression of PHGDH mRNA CTD PMID:17562736 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of PHGDH mRNA CTD PMID:30723492 paracetamol increases expression ISO PHGDH (Homo sapiens) 6480464 Acetaminophen results in increased expression of PHGDH mRNA CTD PMID:29067470 paraquat increases expression EXP 6480464 Paraquat results in increased expression of PHGDH mRNA CTD PMID:32680482 pentachlorophenol decreases expression ISO Phgdh (Mus musculus) 6480464 Pentachlorophenol results in decreased expression of PHGDH mRNA CTD PMID:23892564 perfluorononanoic acid increases expression ISO PHGDH (Homo sapiens) 6480464 perfluoro-n-nonanoic acid results in increased expression of PHGDH mRNA CTD PMID:32588087 perfluorooctane-1-sulfonic acid increases expression ISO PHGDH (Homo sapiens) 6480464 perfluorooctane sulfonic acid results in increased expression of PHGDH mRNA CTD PMID:32588087 and PMID:36864359 perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of PHGDH mRNA CTD PMID:19162173 perfluorooctanoic acid increases expression ISO PHGDH (Homo sapiens) 6480464 perfluorooctanoic acid results in increased expression of PHGDH mRNA CTD PMID:32588087 phenylephrine increases expression EXP 6480464 Phenylephrine results in increased expression of PHGDH mRNA CTD PMID:18158353 PhIP increases expression EXP 6480464 2-amino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine results in increased expression of PHGDH mRNA CTD PMID:15215175 phorone affects expression EXP 6480464 phorone affects the expression of PHGDH mRNA CTD PMID:18198479 picoxystrobin increases expression ISO PHGDH (Homo sapiens) 6480464 picoxystrobin results in increased expression of PHGDH mRNA CTD PMID:33512557 piperonyl butoxide increases expression EXP 6480464 Piperonyl Butoxide results in increased expression of PHGDH mRNA CTD PMID:15890375 pirinixic acid multiple interactions ISO PHGDH (Homo sapiens) 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of PHGDH mRNA CTD PMID:19710929 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of PHGDH mRNA CTD PMID:15890375 piroxicam multiple interactions ISO PHGDH (Homo sapiens) 6480464 Cisplatin promotes the reaction [Piroxicam results in decreased expression of PHGDH mRNA] CTD PMID:21858171 piroxicam decreases expression ISO PHGDH (Homo sapiens) 6480464 Piroxicam results in decreased expression of PHGDH mRNA CTD PMID:21858171 potassium bromate decreases expression ISO PHGDH (Homo sapiens) 6480464 potassium bromate results in decreased expression of PHGDH mRNA CTD PMID:30559759 potassium dichromate increases expression EXP 6480464 Potassium Dichromate results in increased expression of PHGDH protein CTD PMID:18563748 prednisolone decreases expression ISO PHGDH (Homo sapiens) 6480464 Prednisolone results in decreased expression of PHGDH mRNA CTD PMID:19192274 prostaglandin A1 increases metabolic processing ISO Phgdh (Mus musculus) 6480464 prostaglandin A1 analog results in increased metabolism of PHGDH protein CTD PMID:19800325 pyrazinecarboxamide increases expression EXP 6480464 Pyrazinamide results in increased expression of PHGDH mRNA CTD PMID:22431067 pyrimidifen increases expression ISO PHGDH (Homo sapiens) 6480464 pyrimidifen results in increased expression of PHGDH mRNA CTD PMID:33512557 pyrogallol increases expression ISO Phgdh (Mus musculus) 6480464 Pyrogallol results in increased expression of PHGDH mRNA CTD PMID:20362636 pyrogallol multiple interactions ISO Phgdh (Mus musculus) 6480464 Silymarin inhibits the reaction [Pyrogallol results in increased expression of PHGDH mRNA] CTD PMID:20362636 quercetin decreases expression ISO PHGDH (Homo sapiens) 6480464 Quercetin results in decreased expression of PHGDH mRNA CTD PMID:21632981 quercetin increases expression ISO PHGDH (Homo sapiens) 6480464 Quercetin results in increased expression of PHGDH protein CTD PMID:14750173 retinyl acetate increases expression ISO Phgdh (Mus musculus) 6480464 retinol acetate results in increased expression of PHGDH mRNA CTD PMID:16772331 rotenone decreases expression ISO PHGDH (Homo sapiens) 6480464 Rotenone results in decreased expression of PHGDH mRNA CTD PMID:29955902 rotenone increases expression ISO PHGDH (Homo sapiens) 6480464 Rotenone results in increased expression of PHGDH mRNA CTD PMID:33512557 SB 431542 multiple interactions ISO PHGDH (Homo sapiens) 6480464 [LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in decreased expression of PHGDH protein CTD PMID:37664457 silicon dioxide decreases expression ISO PHGDH (Homo sapiens) 6480464 Silicon Dioxide analog results in decreased expression of PHGDH mRNA CTD PMID:23806026 silver atom increases expression ISO PHGDH (Homo sapiens) 6480464 Silver results in increased expression of PHGDH mRNA CTD PMID:26551752 silver(0) increases expression ISO PHGDH (Homo sapiens) 6480464 Silver results in increased expression of PHGDH mRNA CTD PMID:26551752 sodium arsenate decreases expression ISO Phgdh (Mus musculus) 6480464 sodium arsenate results in decreased expression of PHGDH mRNA CTD PMID:21795629 sodium arsenite decreases expression ISO PHGDH (Homo sapiens) 6480464 sodium arsenite results in decreased expression of PHGDH protein CTD PMID:21925251 sodium arsenite decreases expression ISO Phgdh (Mus musculus) 6480464 sodium arsenite results in decreased expression of PHGDH mRNA CTD PMID:37682722 sodium arsenite increases expression ISO PHGDH (Homo sapiens) 6480464 sodium arsenite results in increased expression of PHGDH protein CTD PMID:21925251 sodium aurothiomalate decreases expression ISO PHGDH (Homo sapiens) 6480464 Gold Sodium Thiomalate results in decreased expression of PHGDH mRNA CTD PMID:19192274 sodium fluoride decreases expression ISO Phgdh (Mus musculus) 6480464 Sodium Fluoride results in decreased expression of PHGDH protein CTD PMID:28918527 sodium fluoride increases expression ISO Phgdh (Mus musculus) 6480464 Sodium Fluoride results in increased expression of PHGDH protein CTD PMID:27548804 sulfadimethoxine increases expression EXP 6480464 Sulfadimethoxine results in increased expression of PHGDH mRNA CTD PMID:30047161 sulforaphane increases expression ISO Phgdh (Mus musculus) 6480464 sulforaphane results in increased expression of PHGDH mRNA CTD PMID:30529165 sulforaphane increases expression ISO PHGDH (Homo sapiens) 6480464 sulforaphane results in increased expression of PHGDH mRNA CTD PMID:31838189 sunitinib increases expression ISO PHGDH (Homo sapiens) 6480464 Sunitinib results in increased expression of PHGDH mRNA CTD PMID:31533062 T-2 toxin decreases expression ISO PHGDH (Homo sapiens) 6480464 T-2 Toxin results in decreased expression of PHGDH mRNA CTD PMID:34581912 tamoxifen affects expression ISO Phgdh (Mus musculus) 6480464 Tamoxifen affects the expression of PHGDH mRNA CTD PMID:17555576 Tanshinone I increases expression EXP 6480464 tanshinone results in increased expression of PHGDH mRNA CTD PMID:31108107 Tanshinone I multiple interactions EXP 6480464 tanshinone inhibits the reaction [Estrogens deficiency results in increased methylation of PHGDH promoter] CTD PMID:31108107 tebufenpyrad increases expression ISO PHGDH (Homo sapiens) 6480464 4-chloro-N-((4-(1 and 1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in increased expression of PHGDH mRNA CTD PMID:33512557 temozolomide increases expression ISO PHGDH (Homo sapiens) 6480464 Temozolomide results in increased expression of PHGDH mRNA CTD PMID:31758290 terbutaline increases expression EXP 6480464 Terbutaline results in increased expression of PHGDH mRNA CTD PMID:12423672 tetrachloroethene increases expression ISO Phgdh (Mus musculus) 6480464 Tetrachloroethylene results in increased expression of PHGDH mRNA CTD PMID:28973375 tetrachloromethane multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of PHGDH mRNA] CTD PMID:31150632 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of PHGDH mRNA CTD PMID:30723492 and PMID:31150632 thapsigargin increases expression ISO PHGDH (Homo sapiens) 6480464 Thapsigargin results in increased expression of PHGDH mRNA CTD PMID:22378314 thifluzamide increases expression ISO PHGDH (Homo sapiens) 6480464 thifluzamide results in increased expression of PHGDH mRNA CTD PMID:33512557 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of PHGDH mRNA CTD PMID:23411599 and PMID:34492290 thioacetamide multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of PHGDH mRNA CTD PMID:28943392 titanium dioxide increases expression EXP 6480464 titanium dioxide results in increased expression of PHGDH mRNA CTD PMID:30012374 trichloroethene increases expression ISO Phgdh (Mus musculus) 6480464 Trichloroethylene results in increased expression of PHGDH mRNA CTD PMID:28973375 trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of PHGDH mRNA CTD PMID:33387578 triclosan increases expression ISO PHGDH (Homo sapiens) 6480464 Triclosan results in increased expression of PHGDH mRNA CTD PMID:30510588 trimellitic anhydride increases expression ISO Phgdh (Mus musculus) 6480464 trimellitic anhydride results in increased expression of PHGDH mRNA CTD PMID:19042947 triphenyl phosphate increases expression EXP 6480464 triphenyl phosphate results in increased expression of PHGDH mRNA CTD PMID:30589522 troglitazone increases expression ISO PHGDH (Homo sapiens) 6480464 troglitazone results in increased expression of PHGDH mRNA CTD PMID:19140230 trovafloxacin decreases expression ISO Phgdh (Mus musculus) 6480464 trovafloxacin results in decreased expression of PHGDH mRNA CTD PMID:35537566 tunicamycin increases expression ISO PHGDH (Homo sapiens) 6480464 Tunicamycin results in increased expression of PHGDH mRNA and Tunicamycin results in increased expression of PHGDH protein CTD PMID:22378314 and PMID:29453283 valdecoxib increases expression EXP 6480464 valdecoxib results in increased expression of PHGDH mRNA CTD PMID:24136188 valproic acid decreases methylation ISO PHGDH (Homo sapiens) 6480464 Valproic Acid results in decreased methylation of PHGDH gene CTD PMID:29154799 valproic acid increases expression ISO PHGDH (Homo sapiens) 6480464 Valproic Acid results in increased expression of PHGDH mRNA CTD PMID:25596134 and PMID:29154799 valproic acid affects expression ISO Phgdh (Mus musculus) 6480464 Valproic Acid affects the expression of PHGDH mRNA CTD PMID:17963808 vinclozolin affects expression EXP 6480464 vinclozolin affects the expression of PHGDH mRNA CTD PMID:23034163 zearalenone multiple interactions ISO Phgdh (Mus musculus) 6480464 [Zearalenone co-treated with CGA protein] results in increased expression of PHGDH protein CTD PMID:25058043 zearalenone decreases expression ISO Phgdh (Mus musculus) 6480464 Zearalenone results in decreased expression of PHGDH protein CTD PMID:36252740 zinc atom increases expression ISO PHGDH (Homo sapiens) 6480464 Zinc deficiency results in increased expression of PHGDH mRNA CTD PMID:22171008 zinc(0) increases expression ISO PHGDH (Homo sapiens) 6480464 Zinc deficiency results in increased expression of PHGDH mRNA CTD PMID:22171008 zoledronic acid decreases expression ISO PHGDH (Homo sapiens) 6480464 zoledronic acid results in decreased expression of PHGDH mRNA CTD PMID:24714768 and PMID:25596134