Gene: Phgdh (phosphoglycerate dehydrogenase) Rattus norvegicus
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Symbol: Phgdh
Name: phosphoglycerate dehydrogenase
Description: ENCODES a protein that exhibits phosphoglycerate dehydrogenase activity; INVOLVED IN G1 to G0 transition (ortholog); gamma-aminobutyric acid metabolic process (ortholog); glial cell development (ortholog); PARTICIPATES IN dihydropyrimidine dehydrogenase deficiency pathway; dimethylglycine dehydrogenase deficiency pathway; nonketotic hyperglycinemia pathway; ASSOCIATED WITH 3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 Deficiency (ortholog); amino acid metabolic disorder (ortholog); Breast Neoplasms (ortholog); INTERACTS WITH (R)-adrenaline; 1-bromopropane; 17alpha-ethynylestradiol
AGR Description: Exhibits phosphoglycerate dehydrogenase activity; predicted to be involved in several processes, including G1 to G0 transition, carboxylic acid metabolic process, and nervous system development; orthologous to human PHGDH (phosphoglycerate dehydrogenase).
Merged Description: Exhibits phosphoglycerate dehydrogenase activity; predicted to be involved in several processes, including G1 to G0 transition, carboxylic acid metabolic process, and nervous system development; orthologous to human PHGDH (phosphoglycerate dehydrogenase); PARTICIPATES IN dihydropyrimidine dehydrogenase deficiency pathway; dimethylglycine dehydrogenase deficiency pathway; nonketotic hyperglycinemia pathway; INTERACTS WITH (R)-adrenaline; 1-bromopropane; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 3-PGDH; 3-phosphoglycerate dehydrogenase; D-3-phosphoglycerate dehydrogenase; MGC105399
Orthologs:
Homo sapiens (human) : PHGDH (phosphoglycerate dehydrogenase)  HGNC  Alliance
Mus musculus (house mouse) : Phgdh (3-phosphoglycerate dehydrogenase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Phgdh (phosphoglycerate dehydrogenase)
Pan paniscus (bonobo/pygmy chimpanzee) : PHGDH (phosphoglycerate dehydrogenase)
Canis lupus familiaris (dog) : LOC608055 (D-3-phosphoglycerate dehydrogenase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Phgdh (phosphoglycerate dehydrogenase)
Sus scrofa (pig) : PHGDH (phosphoglycerate dehydrogenase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02200,484,245 - 200,513,564 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02219,959,693 - 219,989,012 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42193,147,943 - 193,177,137 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12193,110,696 - 193,139,891 (-)NCBI
Celera2178,395,133 - 178,424,307 (-)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Phgdh
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 61987
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.