Pgrmc1 (progesterone receptor membrane component 1) - Rat Genome Database

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Gene: Pgrmc1 (progesterone receptor membrane component 1) Rattus norvegicus
Analyze
Symbol: Pgrmc1
Name: progesterone receptor membrane component 1
RGD ID: 70890
Description: Predicted to enable heme binding activity and protein homodimerization activity. Involved in several processes, including learning or memory; modification of synaptic structure; and negative regulation of synapse organization. Located in neuron projection; neuronal cell body; and synapse. Orthologous to human PGRMC1 (progesterone receptor membrane component 1); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 25-Dx; 25Dx; acidic 25 kDa protein; membrane-associated progesterone receptor component 1; membrane-bound progesterone receptor; MPR; VEMA; ventral midline antigen
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X120,698,610 - 120,706,805 (+)NCBIGRCr8
mRatBN7.2X115,832,865 - 115,841,060 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX115,832,884 - 115,888,682 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX117,934,866 - 117,943,066 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X121,504,010 - 121,512,210 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X119,050,166 - 119,058,365 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X123,205,869 - 123,213,880 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX123,205,869 - 123,213,882 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X123,352,144 - 123,360,155 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X8,265,543 - 8,273,667 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X8,271,098 - 8,279,223 (-)NCBI
CeleraX115,065,055 - 115,073,267 (+)NCBICelera
Cytogenetic MapXq34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrotoluene  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-hydroxypropanoic acid  (ISO)
3-chloropropane-1,2-diol  (EXP)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
afimoxifene  (ISO)
amiodarone  (EXP)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsenite(3-)  (ISO)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
captan  (ISO)
carbamazepine  (EXP)
carbon nanotube  (ISO)
cetrorelix  (ISO)
CGP 52608  (ISO)
cisplatin  (ISO)
clofibrate  (EXP)
clozapine  (EXP)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
deoxynivalenol  (ISO)
desogestrel  (ISO)
diethyl maleate  (ISO)
dioxygen  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
enzyme inhibitor  (ISO)
felbamate  (EXP)
fipronil  (EXP)
flavonoids  (EXP)
flutamide  (EXP)
folic acid  (ISO)
folpet  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
gefitinib  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
inulin  (ISO)
isotretinoin  (ISO)
ivermectin  (ISO)
L-ethionine  (EXP)
menadione  (ISO)
nefazodone  (EXP)
nimesulide  (EXP)
omeprazole  (EXP)
oxaliplatin  (EXP)
p-toluidine  (EXP)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (EXP)
phenytoin  (EXP)
picoxystrobin  (ISO)
pirinixic acid  (EXP)
pregnenolone 16alpha-carbonitrile  (EXP)
procymidone  (EXP)
progesterone  (EXP)
quercetin  (ISO)
rac-lactic acid  (ISO)
resveratrol  (EXP)
rotenone  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
tamoxifen  (ISO)
testosterone  (EXP)
testosterone enanthate  (ISO)
thapsigargin  (EXP,ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
trichloroethene  (EXP)
triphenyl phosphate  (ISO)
valproic acid  (ISO)
venlafaxine hydrochloride  (EXP)
vincaleukoblastine  (ISO)
vinclozolin  (EXP)
zinc atom  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Alzheimer's therapeutics targeting amyloid beta 1-42 oligomers I: Abeta 42 oligomer binding to specific neuronal receptors is displaced by drug candidates that improve cognitive deficits. Izzo NJ, etal., PLoS One. 2014 Nov 12;9(11):e111898. doi: 10.1371/journal.pone.0111898. eCollection 2014.
4. Alzheimer's therapeutics targeting amyloid beta 1-42 oligomers II: Sigma-2/PGRMC1 receptors mediate Abeta 42 oligomer binding and synaptotoxicity. Izzo NJ, etal., PLoS One. 2014 Nov 12;9(11):e111899. doi: 10.1371/journal.pone.0111899. eCollection 2014.
5. Gene Data Set MGD Curation, June 12, 2002
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Cloning and expression of VEMA: a novel ventral midline antigen in the rat CNS. Runko E, etal., Mol Cell Neurosci 1999 Dec;14(6):428-43.
9. Isolation and characterization of a novel gene induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in rat liver. Selmin O, etal., Carcinogenesis 1996 Dec;17(12):2609-15.
10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:11087948   PMID:15033482   PMID:15207350   PMID:15489334   PMID:15570619   PMID:15934950   PMID:16279947   PMID:16641100   PMID:17991724   PMID:19946888   PMID:20144686   PMID:20977928  
PMID:21148105   PMID:21730960   PMID:22147012   PMID:22719051   PMID:22778217   PMID:23211561   PMID:23242527   PMID:23376485   PMID:23653459   PMID:25002582   PMID:25253729   PMID:26335282  
PMID:26988023   PMID:27599036   PMID:31748741   PMID:34645803   PMID:34970218  


Genomics

Comparative Map Data
Pgrmc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X120,698,610 - 120,706,805 (+)NCBIGRCr8
mRatBN7.2X115,832,865 - 115,841,060 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX115,832,884 - 115,888,682 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX117,934,866 - 117,943,066 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X121,504,010 - 121,512,210 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X119,050,166 - 119,058,365 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X123,205,869 - 123,213,880 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX123,205,869 - 123,213,882 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X123,352,144 - 123,360,155 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X8,265,543 - 8,273,667 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X8,271,098 - 8,279,223 (-)NCBI
CeleraX115,065,055 - 115,073,267 (+)NCBICelera
Cytogenetic MapXq34NCBI
PGRMC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X119,236,285 - 119,244,466 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX119,236,245 - 119,244,466 (+)EnsemblGRCh38hg38GRCh38
GRCh37X118,370,248 - 118,378,429 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X118,254,291 - 118,262,457 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X118,152,144 - 118,160,310NCBI
CeleraX118,824,941 - 118,833,159 (+)NCBICelera
Cytogenetic MapXq24NCBI
HuRefX107,864,078 - 107,872,271 (+)NCBIHuRef
CHM1_1X118,281,446 - 118,289,662 (+)NCBICHM1_1
T2T-CHM13v2.0X117,614,039 - 117,622,220 (+)NCBIT2T-CHM13v2.0
Pgrmc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X35,861,846 - 35,869,732 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX35,861,859 - 35,869,732 (+)EnsemblGRCm39 Ensembl
GRCm38X36,598,193 - 36,606,079 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX36,598,206 - 36,606,079 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X34,138,220 - 34,146,074 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X33,029,670 - 33,037,524 (+)NCBIMGSCv36mm8
CeleraX23,322,277 - 23,330,131 (+)NCBICelera
Cytogenetic MapXA3.3NCBI
cM MapX21.0NCBI
Pgrmc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955534698,734 - 706,946 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955534698,895 - 706,586 (-)NCBIChiLan1.0ChiLan1.0
PGRMC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X118,631,349 - 118,639,583 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X118,634,953 - 118,643,187 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X108,282,958 - 108,291,187 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X118,711,495 - 118,719,714 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX118,711,495 - 118,719,714 (+)Ensemblpanpan1.1panPan2
PGRMC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X91,329,243 - 91,337,951 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX91,329,243 - 91,337,951 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX77,405,200 - 77,413,908 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X93,069,899 - 93,078,605 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX93,069,840 - 93,078,601 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X90,522,743 - 90,531,448 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X92,281,492 - 92,290,197 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X92,010,000 - 92,018,705 (+)NCBIUU_Cfam_GSD_1.0
Pgrmc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X90,353,427 - 90,361,506 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647910,625,889 - 10,634,136 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647910,625,989 - 10,634,058 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PGRMC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX97,735,244 - 97,743,423 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X97,735,402 - 97,743,424 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X113,925,761 - 113,933,800 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PGRMC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366606531,998,876 - 32,007,022 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pgrmc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248953,264,798 - 3,273,529 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248953,265,326 - 3,273,531 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pgrmc1
29 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:311
Count of miRNA genes:188
Interacting mature miRNAs:235
Transcripts:ENSRNOT00000017101
Prediction methods:Miranda, Pita, Pita,Targetscan, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598856Memor1Memory QTL 11.9exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)X103312877148312877Rat
1598872Memor14Memory QTL 144.5exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X93956491138956491Rat
1598809Memor15Memory QTL 154.4exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X103312877148312877Rat
738025Stresp3Stress response QTL 34.610.0066stress-related behavior trait (VT:0010451)defensive burying - approachX100567703150256146Rat
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat
738029Stresp2Stress response QTL 23.40.0004stress-related behavior trait (VT:0010451)defensive burying - approachX112934952138400867Rat
61431Cia19Collagen induced arthritis QTL 194.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X65612192120568734Rat
5685004Bss104Bone structure and strength QTL 1043.9tibia area (VT:1000281)tibia area measurement (CMO:0001382)X113805422126975220Rat
10059603Bw174Body weight QTL 1743.40.025body mass (VT:0001259)body weight (CMO:0000012)X113937816152453651Rat
724551Glom1Glomerulus QTL 12.80.0004kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)X75294106120294106Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X41052407146860749Rat

Markers in Region
RH139267  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21930,511,961 - 30,512,089 (+)MAPPERmRatBN7.2
Rnor_6.01934,204,203 - 34,204,330NCBIRnor6.0
Rnor_5.01945,084,621 - 45,084,748UniSTSRnor5.0
RGSC_v3.41932,324,466 - 32,324,593UniSTSRGSC3.4
Celera1929,992,287 - 29,992,414UniSTS
RH 3.4 Map19234.8UniSTS
Cytogenetic Map19q11UniSTS
Cytogenetic MapXq12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000017101   ⟹   ENSRNOP00000017101
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX115,832,884 - 115,888,682 (+)Ensembl
Rnor_6.0 EnsemblX123,205,869 - 123,213,882 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000079231   ⟹   ENSRNOP00000071066
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX123,205,891 - 123,212,727 (+)Ensembl
RefSeq Acc Id: NM_021766   ⟹   NP_068534
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X120,698,610 - 120,706,805 (+)NCBI
mRatBN7.2X115,832,865 - 115,841,060 (+)NCBI
Rnor_6.0X123,205,869 - 123,213,880 (+)NCBI
Rnor_5.0X123,352,144 - 123,360,155 (+)NCBI
RGSC_v3.4X8,265,543 - 8,273,667 (-)RGD
CeleraX115,065,055 - 115,073,267 (+)RGD
Sequence:
RefSeq Acc Id: NP_068534   ⟸   NM_021766
- UniProtKB: P70580 (UniProtKB/Swiss-Prot),   O70606 (UniProtKB/Swiss-Prot),   Q549C4 (UniProtKB/Swiss-Prot),   A6JMF3 (UniProtKB/TrEMBL),   A0A0H2UHK2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000071066   ⟸   ENSRNOT00000079231
Ensembl Acc Id: ENSRNOP00000017101   ⟸   ENSRNOT00000017101
Protein Domains
Cytochrome b5 heme-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P70580-F1-model_v2 AlphaFold P70580 1-195 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701981
Promoter ID:EPDNEW_R12504
Type:multiple initiation site
Name:Pgrmc1_1
Description:progesterone receptor membrane component 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X123,205,872 - 123,205,932EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:70890 AgrOrtholog
BioCyc Gene G2FUF-1318 BioCyc
Ensembl Genes ENSRNOG00000012786 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055025275 UniProtKB/Swiss-Prot
  ENSRNOG00060019057 UniProtKB/Swiss-Prot
  ENSRNOG00065010138 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000017101 UniProtKB/TrEMBL
  ENSRNOT00000017101.7 UniProtKB/Swiss-Prot
  ENSRNOT00055043581 UniProtKB/Swiss-Prot
  ENSRNOT00060032952 UniProtKB/Swiss-Prot
  ENSRNOT00065016336 UniProtKB/Swiss-Prot
Gene3D-CATH 3.10.120.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:5599449 IMAGE-MGC_LOAD
InterPro Cyt_B5-like_heme/steroid-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyt_B5-like_heme/steroid_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cytochrome_b5-MAPR/VMP1_fams UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:291948 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72462 IMAGE-MGC_LOAD
NCBI Gene 291948 ENTREZGENE
PANTHER MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Cyt-b5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pgrmc1 PhenoGen
RatGTEx ENSRNOG00000012786 RatGTEx
  ENSRNOG00055025275 RatGTEx
  ENSRNOG00060019057 RatGTEx
  ENSRNOG00065010138 RatGTEx
SMART Cyt-b5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF55856 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0H2UHK2 ENTREZGENE, UniProtKB/TrEMBL
  A6JMF3 ENTREZGENE, UniProtKB/TrEMBL
  O70606 ENTREZGENE
  P70580 ENTREZGENE, UniProtKB/Swiss-Prot
  Q549C4 ENTREZGENE
UniProt Secondary O70606 UniProtKB/Swiss-Prot
  Q549C4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-07-09 Pgrmc1  progesterone receptor membrane component 1      Symbol and Name updated to reflect Human and Mouse nomenclature 70877 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_drugs mRNA expression is induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) 70623