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Gene: Pgrmc1 (progesterone receptor membrane component 1) Mus musculus
Symbol: Pgrmc1
Name: progesterone receptor membrane component 1
Description: Exhibits heme binding activity. Predicted to be involved in several processes, including heme biosynthetic process; learning or memory; and positive regulation of protein localization to plasma membrane. Localizes to mitochondrial outer membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Used to study non-alcoholic fatty liver disease. Orthologous to human PGRMC1 (progesterone receptor membrane component 1); INTERACTS WITH 1,2-dichloroethane; 17alpha-ethynylestradiol; 2,3',4,4',5-Pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA415812; HPR6.6; membrane-associated progesterone receptor component 1; mPR; PPMR; Vema
Homo sapiens (human) : PGRMC1 (progesterone receptor membrane component 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pgrmc1 (progesterone receptor membrane component 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pgrmc1 (progesterone receptor membrane component 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PGRMC1 (progesterone receptor membrane component 1)
Canis lupus familiaris (dog) : PGRMC1 (progesterone receptor membrane component 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pgrmc1 (progesterone receptor membrane component 1)
Sus scrofa (pig) : PGRMC1 (progesterone receptor membrane component 1)
Chlorocebus sabaeus (African green monkey) : PGRMC1 (progesterone receptor membrane component 1)
Heterocephalus glaber (naked mole-rat) : Pgrmc1 (progesterone receptor membrane component 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 EnsemblX36,598,206 - 36,606,079 (+)EnsemblGRCm38mm10GRCm38
GRCm38X36,598,193 - 36,606,079 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37X34,138,220 - 34,146,074 (+)NCBIGRCm37mm9NCBIm37
MGSCv36X33,029,670 - 33,037,524 (+)NCBImm8
CeleraX23,322,277 - 23,330,131 (+)NCBICelera
Cytogenetic MapXA3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Pgrmc1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736221
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.