Bss104 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL: Bss104 (Bone structure and strength QTL 104) Rattus norvegicus

Symbol: Bss104
Name: Bone structure and strength QTL 104
RGD ID: 5685004
Trait: tibia area   (VT:1000281)    
Measurement Type: tibia area measurement   (CMO:0001382)    
LOD Score: 3.9
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X113,805,422 - 126,975,220RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0X121,442,246 - 134,627,946RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0X121,580,137 - 134,700,747RGDRnor5.0
RGSC_v3.4X10,563,466 - 134,157,626RGDRGSC3.4
Cross Type: Not Available
Strains Crossed: GK/KyoSwe F344/DuCrlSwe 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View
osteoporosis  (IAGP)

Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait
tibia area  (IDA)

Rat Strain
F344/DuCrlSwe  (IEA)
GK/KyoSwe  (IEA)

References

References - curated
1. Lagerholm S, etal., PLoS One. 2011;6(7):e22462. Epub 2011 Jul 27.

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
3295Rhox5Rhox homeobox family member 5X116536207116541972Rat
70890Pgrmc1progesterone receptor membrane component 1X115832865115841060Rat
3593Rpl39ribosomal protein L39X116327183116330211Rat
70958Gria3glutamate ionotropic receptor AMPA type subunit 3X120238515120504106Rat
708510Akap14A-kinase anchoring protein 14X116395512116410697Rat
620692XiapX-linked inhibitor of apoptosisX120890537120938413Rat
2990Lamp2lysosomal-associated membrane protein 2X117173097117222090Rat
628741Il13ra1interleukin 13 receptor subunit alpha 1X115348860115408682Rat
620994Atp1b4ATPase Na+/K+ transporting family member beta 4X117087284117108023Rat
727965Wdr44WD repeat domain 44X114481890114587307Rat
620353Slc25a5solute carrier family 25 member 5X116031896116034963Rat
1305365Tesltestis derived transcript-likeX114680227114693795Rat
727788Tmem255atransmembrane protein 255AX116970793117035008Rat
1559646Klhl13kelch-like family member 13X113942309114107355Rat
1563789Rhox12Rhox homeobox family member 12X116890562116897981Rat
1561445RGD1561445similar to novel proteinX115675412115725950Rat
1563975Tex13cTEX13 family member CX122469125122471627Rat
1563150RGD1563150similar to B-cell translocation gene 1X116749728116754643Rat
1561678Tenm1teneurin transmembrane protein 1X121400466122289877Rat
1559928Slc25a43solute carrier family 25, member 43X115977437116011789Rat
1311230C1galt1c1C1GALT1-specific chaperone 1X117378123117382620Rat
1563873Dcaf12l1DDB1 and CUL4 associated factor 12-like 1X123695286123698905Rat
1566035RGD1566035similar to protein tyrosine phosphatase 4a1X116789584116790544Rat
1563189Rhox7Rhox homeobox family member 7X116627645116635721Rat
1359693Rnf113a1ring finger protein 113A1X116428037116429164Rat
1562408Sh2d1aSH2 domain containing 1AX121373693121401923Rat
1563291Rhox10reproductive homeobox 10X116850460116854898Rat
1561047Rhox8reproductive homeobox 8X116584742116588365Rat
1563086Sowahdsosondowah ankyrin repeat domain family member DX116292030116293660Rat
1560264Upf3bUPF3B, regulator of nonsense mediated mRNA decayX116335308116353332Rat
1562042Stag2stromal antigen 2X120974687121105677Rat
1359534Ube2aubiquitin-conjugating enzyme E2AX116114339116125076Rat
1564707Dock11dedicator of cytokinesis 11X115131720115314854Rat
1560119RGD1560119similar to actin alpha 1 skeletal muscle proteinX121159206121162455Rat
1560124RGD1560124similar to ribosomal protein L10aX117620592117621326Rat
1563844Rhox9reproductive homeobox 9X116641863116644714Rat
1560768Dcaf12l2DDB1 and CUL4 associated factor 12-like 2X123293761123296550Rat
1359559Actrt1actin-related protein T1X125584102125585455Rat
1359439Zcchc12zinc finger CCHC-type containing 12X115433444115436691Rat
1585082Septin6septin 6X116153255116230334Rat
1586045LOC367694similar to Fumarate hydratase, mitochondrial precursor (Fumarase)X118692571118694745Rat
1565430RGD1565430similar to RIKEN cDNA 1700001F22X126731780126732483Rat
1585073LOC691344similar to Breast carcinoma amplified sequence 2 homolog (DNA amplified in mammary carcinoma 1 protein)X116026387116027059Rat
1566390Mcts1MCTS1, re-initiation and release factorX117350723117362504Rat
1566363Akap17bA kinase (PRKA) anchor protein 17BX115843263115881597Rat
1583847LOC302804hypothetical LOC302804X126904676126906513Rat
1564494Cul4bcullin 4BX117287481117326688Rat
1566387RGD1566387similar to hypothetical proteinX114972836115005286Rat
1563524Hspd1-ps21heat shock protein 1, pseudogene 21X125679740125680618Rat
1587436LOC691151similar to 40S ribosomal protein S2X120749512120753948Rat
1565032RGD1565032similar to transcription elongation factor B (SIII), polypeptide 2X115936938115937292Rat
1565955NkapNFKB activating proteinX116373031116392677Rat
1566309Zbtb33zinc finger and BTB domain containing 33X116963337116970547Rat
1561623Thoc2THO complex 2X120634966120749569Rat
1560927RGD1560927RGD1560927X116441825116444647Rat
1560955Ndufa1NADH:ubiquinone oxidoreductase subunit A1X116424223116427875Rat
1566129RGD1566129similar to Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)X124880957124888417Rat
1564332Rhox11Rhox homeobox family member 11X116871847116880098Rat
1584677LOC681067similar to RIKEN cDNA 1700001F22X124788553124789270Rat
1564541Steep1STING1 ER exit protein 1X116087626116114159Rat
1565307Rhox4greproductive homeobox 4GX116472094116477855Rat
1566184RGD1566184similar to Testis derived transcriptX114757064114815923Rat
1565451Lonrf3LON peptidase N-terminal domain and ring finger 3X115565214115603886Rat
1588662LOC691030similar to RIKEN cDNA 1700001F22X123264998123265711Rat
1594344LOC503425similar to 40S ribosomal protein S15 (RIG protein)X115101013115101602Rat
1586289LOC691215hypothetical protein LOC691215X117556991117756327Rat
1583341Prr32proline rich 32X123977960123979917Rat
1586244LOC691267similar to Protein C20orf155 homologX116707078116712324Rat
1590912LOC298327similar to testis derived transcript isoform 1X114872762114873984Rat
1586264Rhox13Rhox homeobox family member 13X116911157116917938Rat
1586238LOC691273similar to Protein C20orf155 homologX116677939116679090Rat
1586239LOC691272similar to reproductive homeobox on X chromosome, 11X116688163116695111Rat
1596590LOC683903similar to High mobility group protein 1 (HMG-1) (High mobility group protein B1) (Amphoterin) (Heparin-binding protein p30)X125866402125867050Rat
1593267LOC298175similar to stem cell derived neuronal survival protein precursorX119699856119700275Rat
1597157LOC305639similar to heat shock protein 8X124067885124069814Rat
1596788LOC681300similar to CXXC finger 5X126891110126892526Rat
1596967LOC678717similar to eukaryotic translation initiation factor 3, subunit 12X120567963120568598Rat
1588607Rhox2Rhox homeobox family member 2X116507488116514240Rat
1594336LOC503477similar to L-lactate dehydrogenase A chain (LDH-A) (LDH muscle subunit) (LDH-M)X124938528124939351Rat
1594337LOC503475similar to HMG2 like isoform 1X124791570124792075Rat
1598239LOC367975similar to B-cell translocation gene 1X116794228116805478Rat
1598248LOC367925similar to glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)-likeX124948493124949499Rat
2301305Rhox3reproductive homeobox on X chromosome 3X116482945116487394Rat
2319295LOC100361883mitochondrial ribosomal protein L30X115956680115957166Rat
2322277LOC100360376hypothetical LOC100360376X123861955123865635Rat
2322526LOC100360224hypothetical LOC100360224X122505315122506003Rat
2321855LOC100364002reproductive homeobox 9-likeX116560244116562636Rat
2321936LOC100360521mitochondrial ribosomal protein S36-likeX122467665122467913Rat
2322721LOC100360128CDNA sequence BC049702-likeX117151627117153132Rat
2323548LOC100363191tubulin, gamma 1-likeX119455925119456663Rat
2324802LOC100363087estrogen receptor binding site associated antigen 9-likeX121289238121289878Rat
6489636LOC100911920zinc finger protein ZPR1-likeX119774008119781347Rat
6502223LOC100909656glyceraldehyde-3-phosphate dehydrogenase-likeX124869932124870723Rat
6500424NkrfNFKB repressing factorX116126341116144577Rat
7519078Ct47b1cancer/testis antigen family 47, member B1X115651472115655191Rat
7506435LOC102555213uncharacterized LOC102555213X124466651124468789Rat
7663400LOC102548382glyceraldehyde-3-phosphate dehydrogenase-likeX118185012118206590Rat
7650932LOC102553553uncharacterized LOC102553553X115025996115030878Rat
7642968LOC102549210L-lactate dehydrogenase A chain-likeX122549678122552543Rat
7611199LOC102550812uncharacterized LOC102550812X125223196125303856Rat
7669826LOC102553384protein crumbs homolog 1-likeX126583668126588654Rat
9081780LOC103690899histidine triad nucleotide-binding protein 1 pseudogeneX114629601114636435Rat
9345774LOC103690894uncharacterized LOC103690894X114922993114939876Rat
11359441LOC10834925260S ribosomal protein L23 pseudogeneX121754412121754975Rat
11454080LOC108349247uncharacterized LOC108349247X113934651113951129Rat
11417755LOC108349198cytochrome c oxidase subunit NDUFA4 pseudogeneX126399588126399833Rat
11373868LOC108349149igE-binding protein-likeX116664953116666436Rat
11409794LOC108349250actin, cytoplasmic 2-likeX117902835117903594Rat
11387321LOC108349153glyceraldehyde-3-phosphate dehydrogenase pseudogeneX123195230123198628Rat
11391862LOC10834919560S ribosomal protein L7a pseudogeneX118279924118280718Rat
11478890LOC108349193glyceraldehyde-3-phosphate dehydrogenase pseudogeneX114319412114321561Rat
11518088LOC108349199glyceraldehyde-3-phosphate dehydrogenase pseudogeneX126965477126966448Rat
41354497LOC120099455small nucleolar RNA SNORA42/SNORA80 familyX117874309117874425Rat
41378756LOC120099264protein SEC13 homologX123733294123742416Rat
41355609LOC120099489small nucleolar RNA SNORA17X117548920117549051Rat
41284281LOC120099346heat shock protein HSP 90-beta-likeX124335515124337028Rat
41383546LOC120099269uncharacterized LOC120099269X124406821124447609Rat
41279441LOC120099252GTPase NRas-likeX116756806116763275Rat
41325721LOC120099203uncharacterized LOC120099203X125508395125647104Rat
41385866LOC120099452small nucleolar RNA SNORA36 familyX116009779116009910Rat
41388056LOC120099476small nucleolar RNA SNORA48X115916685115916825Rat
41146332NEWGENE_40938314transfer RNA serine (anticodon AGA)X121251163121251237Rat
41388172LOC12009935740S ribosomal protein S27-likeX120201439120201694Rat
41093266LOC120093120high mobility group protein B4-likeX126735348126736018Rat
41146938LOC120099169keratinocyte proline-rich protein-likeX116572842116577387Rat
41149933LOC120099459small nucleolar RNA SNORA1X116020859116020995Rat
41331878LOC120099449small nucleolar RNA SNORA69X116327776116327909Rat
41370240LOC120099528U2 spliceosomal RNAX121161958121162061Rat
41183603LOC120099417U6 spliceosomal RNAX115600746115600818Rat
41185080LOC120099499small nucleolar RNA SNORA17X121544402121544533Rat
41185184LOC120099448small Cajal body-specific RNA 13X115087944115088214Rat
41270159LOC120099173tyrosine-protein kinase Fer-likeX120637118120638167Rat
41130514LOC120099418U6 spliceosomal RNAX114663691114663792Rat
41130542LOC120099176igE-binding protein-likeX123925106123930062Rat
41295416LOC120099175uncharacterized LOC120099175X123357769123362512Rat
40975408LOC120099475small nucleolar RNA SNORA48X116931587116931725Rat
41341586NEWGENE_40926764transfer RNA proline (anticodon AGG)X116027434116027514Rat
41014667LOC120099174MLV-related proviral Env polyprotein-likeX122620730122623492Rat
40930597LOC120099172high mobility group protein B1-likeX118058455118059327Rat
40983609LOC120099404U6 spliceosomal RNAX125329941125330045Rat
40960803LOC120099217uncharacterized LOC120099217X116791039116793489Rat
41009708LOC120099216myelin-associated neurite-outgrowth inhibitor-likeX116834576116835163Rat
40970234LOC120099168proline-rich extensin-like protein EPR1X116571246116572833Rat
41046912LOC120099301uncharacterized LOC120099301X114425480114471782Rat
41078949LOC120099170intraflagellar transport protein 52 homologX116594807116598029Rat
41338750LOC120099282cysteine-rich perinuclear theca protein 1-likeX118533863118534605Rat
41041398LOC120099550U4 spliceosomal RNAX123006992123007124Rat
41041497LOC120099177FUN14 domain-containing protein 2-likeX124496808124497966Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
33893D7Mit15150X124600195124600383Ratregion
37078DXRat22227X122067615122067837Ratregion
34783DXRat21148X125812805125812949Ratregion
34825DXRat20175X113805422113805597Ratregion
39724DXRat103133X126975089126975220Ratregion
39996DXRat101156X120948681120948841Ratregion
41396DXRat100157X115075611115075776Ratregion
41624DXRat99145X117002093117002232Ratregion
43151DXRat132201X116926119116926150Ratregion
43406DXGot57260X120556020120556280Ratregion
43947DXWox3130X120568566120568734Ratregion
43950DXGot56163X121375172121375335Ratregion
43955DXGot54126X126441996126442122Ratregion
60686DXGot48250X116647192116647444Ratregion
60687DXGot4998X116904115116904211Ratregion
60688DXGot50148X115310181115310329Ratregion
60689DXGot51204X116074418116074624Ratregion
60690DXGot52167X117722055117722222Ratregion
60690DXGot52167X117722055117722222Ratregion
60691DXGot53257X116199160116199418Ratregion
60692DXGot58133X126421699126421832Ratregion
60695DXGot63147X116269250116269397Ratregion
66722DXMco2277X121505375121505657Ratregion
1636110DXGot166298X122933940122934238Ratregion
1633894DXWox35244X116539292116539536Ratregion
7205926PMC28413P1115X116761789116761904Ratregion
5035581DBX87X116167281116167369Ratregion
5035610DXS8324122X117362343117362465Ratregion
5031214DXS790682X120977573120977655Ratregion
5033845RH140330146X115436518115436664Ratregion
5028615AI451128287X113942335113942622Ratregion
7205800D1S2012E0X115210686115211098Ratregion
5028757RH142214155X116541446116541601Ratregion
5034213RH141795195X117289193117289388Ratregion
5034323AI029857182X116482893116484406Ratregion
5034916AI008298220X116393490116393710Ratregion
5028305DXMit238114X115320656115320770Ratregion
5031193RH102301153X115314413115314566Ratregion
5051611AW260253127X116970302116970429Ratregion
5054355RH143176113X120436857120436970Ratregion
5057514AA819641201X117178827117179028Ratregion
5055771RH143993205X117358385117358590Ratregion
5056655RH144503245X116226921116227165Ratregion
5052567AU023707168X115603531115603699Ratregion
5059988BE103656190X120674843120675033Ratregion
5050796RH134263210X116335393116335603Ratregion
5053769RH142840184X121514665121514849Ratregion
5054303RH143147137X115176803115176940Ratregion
5054651RH143347107X115204825115205309Ratregion
5045026RH130940197X116087909116088106Ratregion
5046464RH131768182X116970298116970480Ratregion
5047300RH132248200X116126415116126615Ratregion
5042888RH129704182X117057329117057511Ratregion
5043294RH129944157X121394412121394569Ratregion
5040060RH128066185X126894182126894368Ratregion
5041038RH128627208X119708403119708611Ratregion
5041038RH128627208X119708403119708611Ratregion
5076992RH139497180X115436360115436540Ratregion
5074828RH138242123X122297661122297784Ratregion
5077756RH139940196X115603643115603839Ratregion
5071270RH134985184X115314589115314773Ratregion
5073546RH137499202X117376837117377039Ratregion
5067692AU047593283X124194668124194946Ratregion
5067994AU047413142X121719358121719504Ratregion
5068024AU047395212X126609746126609953Ratregion
5068112AU047340148X122095371122095519Ratregion
5069528AU046438261X117344411117344672Ratregion
5069694AU046333175X121172635121172810Ratregion
5060140AI072432187X116156950116157137Ratregion
5062392BF397876161X115600212115600373Ratregion
5060100BF388493202X115844128115844330Ratregion
5061890BI294036164X115598521115598685Ratregion
5065140AI044873220X116395190116395411Ratregion
5065278BE121346101X116153470116153571Ratregion
5062394BE106633150X121436008121436158Ratregion
5063114BE107180214X117181960117182174Ratregion
5066374AU048395273X118590796118591071Ratregion
5084348AI408836243X116327367116327610Ratregion
5089691AU049305157X119726206119726363Ratregion
5089735AU049332266X122269668122269934Ratregion
5084872AI171612172X116124645116124817Ratregion
5082149BI280022171X117620601117620772Ratregion
5088509AU048612265X118411244118411509Ratregion
5088589AU048659156X126536618126536774Ratregion
5080958RH141881190X116393852116394042Ratregion
5084764AI00834292X116154493116154585Ratregion
5081615BE117640170X116339316116339486Ratregion
5502835KLHL13187X113974248113974984Ratregion
5503322UniSTS:238018319X120636361120636680Ratregion
5503210ha20280X125999885126000624Ratregion
5504054px-48d2169X115240001115240170Ratregion
5507741REN51965251X120977508120977759Ratregion
5507743REN51966258X120977746120978004Ratregion
5507745REN51964267X120977260120977527Ratregion
5507747REN52332218X121057921121058139Ratregion
5507749REN52504274X121095306121095580Ratregion
5507751REN52551258X121104358121104616Ratregion
5507753REN52552253X121104600121104853Ratregion
5507755REN52553262X121104812121105074Ratregion
5503996px-14c7137X116106432116106569Ratregion
5504060px-58a599X126688746126688845Ratregion
5505658UniSTS:4885321443X116292100116293543Ratregion
5506557ODZ1_364664X121404912121405576Ratregion
5501982MARC_21759-21760:1023907404:5752X116091612116092364Ratregion
5500292D20S1001100X116392481116392581Ratregion
5500332GDB:193196783X115306844115307626Ratregion
5500815stSG6336851139X121103852121104991Ratregion
5500495RH126553249X116088325116088574Ratregion
5503320UniSTS:238015122X116970304116970426Ratregion
5501309ECD13650587X120975484120976071Ratregion
5501540G16011149X117316169117316318Ratregion
5501247PMC166414P3170X120920962120921132Ratregion
Position Markers

Flank 1: (DXRat20)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X113,805,422 - 113,805,597 (+)MAPPER
Rnor_6.0X121,442,246 - 121,442,420NCBI
Rnor_5.0X121,580,137 - 121,580,311UniSTS
RGSC_v3.4X10,563,466 - 10,563,641RGD
RGSC_v3.4X10,563,467 - 10,563,641UniSTS
RGSC_v3.1X10,569,023 - 10,569,197RGD
CeleraX113,034,390 - 113,034,564UniSTS
SHRSP x BN MapX34.2699UniSTS
SHRSP x BN MapX34.2699RGD
Peak: (DXRat20)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X113,805,422 - 113,805,597 (+)MAPPER
Rnor_6.0X121,442,246 - 121,442,420NCBI
Rnor_5.0X121,580,137 - 121,580,311UniSTS
RGSC_v3.4X10,563,466 - 10,563,641RGD
RGSC_v3.4X10,563,467 - 10,563,641UniSTS
RGSC_v3.1X10,569,023 - 10,569,197RGD
CeleraX113,034,390 - 113,034,564UniSTS
SHRSP x BN MapX34.2699UniSTS
SHRSP x BN MapX34.2699RGD
Flank 2: (DXRat103)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X126,975,089 - 126,975,220 (+)MAPPER
Rnor_6.0X134,627,816 - 134,627,946NCBI
Rnor_5.0X134,700,617 - 134,700,747UniSTS
RGSC_v3.4X134,157,190 - 134,157,626RGD
RGSC_v3.4X134,157,230 - 134,157,360UniSTS
RGSC_v3.1X134,230,663 - 134,230,793RGD
CeleraX125,926,181 - 125,926,311UniSTS
RH 3.4 MapX907.8UniSTS
RH 3.4 MapX907.8RGD
SHRSP x BN MapX37.58UniSTS
SHRSP x BN MapX37.58RGD


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X41052407146860749Rat
61431Cia19Collagen induced arthritis QTL 194.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X65612192120568734Rat
724551Glom1Glomerulus QTL 12.80.0004kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)X75294106120294106Rat
1598872Memor14Memory QTL 144.5exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X93956491138956491Rat
738025Stresp3Stress response QTL 34.610.0066stress-related behavior trait (VT:0010451)defensive burying - approachX100567703150256146Rat
1598809Memor15Memory QTL 154.4exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X103312877148312877Rat
1598856Memor1Memory QTL 11.9exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)X103312877148312877Rat
738029Stresp2Stress response QTL 23.40.0004stress-related behavior trait (VT:0010451)defensive burying - approachX112934952138400867Rat
5685004Bss104Bone structure and strength QTL 1043.9tibia area (VT:1000281)tibia area measurement (CMO:0001382)X113805422126975220Rat
10059603Bw174Body weight QTL 1743.40.025body mass (VT:0001259)body weight (CMO:0000012)X113937816152453651Rat
634346Insul4Insulin level QTL 40blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)X126975089152453651Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_general number of animals used: 19 parental GK, 20 parental F344, 37 F1 and 206 F2 rats 5684953
qtl_general lineage: F1 animals from both the reciprocal crosses were used; 2 seperate F2 intercrosses were generated, one from grandmaternal GK and grandpaternal F344, the other from grandmaternal F344 and grandpaternal GK 5684953
qtl_general measurement method: at 215 days (mean age) rats kept under controlled conditions were sacrificed and left tibia was subjected to two-dimensional dual energy X-ray absorptiometry using a PIXImusTM densitometer (GE Lunar, Madison, WI) 5684953
qtl_general software used: user-defined region of bone area measured using GE Lunar software 5684953
qtl_general this region (52-74 cM) is determined in grandmaternal F344/grandpaternal GK and grandmaternal GK/grandpaternal F344 F2 female rats 5684953