C14h4orf19 (similar to human chromosome 4 open reading frame 19) - Rat Genome Database

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Gene: C14h4orf19 (similar to human chromosome 4 open reading frame 19) Rattus norvegicus
Analyze
Symbol: C14h4orf19
Name: similar to human chromosome 4 open reading frame 19
RGD ID: 1561612
Description: Orthologous to human C4orf19 (chromosome 4 open reading frame 19); INTERACTS WITH 17beta-estradiol (ortholog); 3-methylcholanthrene (ortholog); 4,4'-sulfonyldiphenol (ortholog).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ADP/ATP translocase 3; ADP/ATP translocase 3-like; hypothetical protein LOC498368; LOC100909799; LOC498368; similar to RIKEN cDNA 0610040J01; uncharacterized protein C4orf19 homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81444,740,965 - 44,832,180 (-)NCBIGRCr8
mRatBN7.21444,387,386 - 44,478,344 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1444,387,393 - 44,478,041 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1444,750,308 - 44,774,441 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01446,050,240 - 46,074,373 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01444,530,364 - 44,554,499 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01446,050,752 - 46,134,770 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1446,050,750 - 46,054,022 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01445,855,971 - 45,858,411 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41447,040,366 - 47,158,361 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1443,528,486 - 43,618,262 (-)NCBICelera
Cytogenetic Map14p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
cholestasis  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Genomics

Comparative Map Data
C14h4orf19
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81444,740,965 - 44,832,180 (-)NCBIGRCr8
mRatBN7.21444,387,386 - 44,478,344 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1444,387,393 - 44,478,041 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1444,750,308 - 44,774,441 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01446,050,240 - 46,074,373 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01444,530,364 - 44,554,499 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01446,050,752 - 46,134,770 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1446,050,750 - 46,054,022 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01445,855,971 - 45,858,411 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41447,040,366 - 47,158,361 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1443,528,486 - 43,618,262 (-)NCBICelera
Cytogenetic Map14p11NCBI
C4orf19
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38437,453,255 - 37,593,510 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl437,453,925 - 37,623,495 (+)EnsemblGRCh38hg38GRCh38
GRCh37437,455,547 - 37,595,132 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36437,131,947 - 37,271,527 (+)NCBINCBI36Build 36hg18NCBI36
Celera437,895,413 - 38,034,606 (+)NCBICelera
Cytogenetic Map4p14NCBI
HuRef436,779,258 - 36,919,665 (+)NCBIHuRef
CHM1_1437,454,676 - 37,594,129 (+)NCBICHM1_1
T2T-CHM13v2.0437,421,994 - 37,562,645 (+)NCBIT2T-CHM13v2.0
0610040J01Rik
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39563,969,833 - 64,056,968 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl563,969,706 - 64,056,968 (+)EnsemblGRCm39 Ensembl
GRCm38563,811,657 - 63,899,626 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl563,812,363 - 63,899,625 (+)EnsemblGRCm38mm10GRCm38
MGSCv37564,203,734 - 64,290,858 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36564,091,499 - 64,178,754 (+)NCBIMGSCv36mm8
Celera561,110,672 - 61,191,582 (+)NCBICelera
Cytogenetic Map5C3.1NCBI
cM Map532.8NCBI
CUNH4orf19
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554439,540,825 - 9,565,119 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554439,540,047 - 9,628,483 (-)NCBIChiLan1.0ChiLan1.0
C3H4orf19
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2337,642,593 - 37,784,421 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1437,833,958 - 37,976,357 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0431,781,515 - 31,922,413 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1437,742,659 - 37,778,767 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl437,742,659 - 37,808,076 (+)Ensemblpanpan1.1panPan2
C3H4orf19
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1374,570,092 - 74,656,732 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl374,570,708 - 74,572,454 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha377,117,898 - 77,202,337 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0375,351,437 - 75,436,158 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1374,617,844 - 74,702,239 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0374,764,882 - 74,849,234 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0375,142,817 - 75,227,298 (-)NCBIUU_Cfam_GSD_1.0
CUNH4orf19
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528540,683,694 - 40,777,942 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364825,520,275 - 5,614,537 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364825,592,667 - 5,614,527 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
C8H4orf19
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl829,013,082 - 29,103,160 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1829,012,884 - 29,103,163 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2830,428,959 - 30,516,355 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CUNH4orf19
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12712,690,136 - 12,821,129 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2712,690,608 - 12,694,799 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604759,110,635 - 59,152,378 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in C14h4orf19
315 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:90
Count of miRNA genes:71
Interacting mature miRNAs:84
Transcripts:ENSRNOT00000002982
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313089Bss81Bone structure and strength QTL 813.40.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)143766971982669719Rat
1581500Renag1Renal agenesis QTL 1kidney development trait (VT:0000527)percentage of study population developing unilateral renal agenesis during a period of time (CMO:0000940)14817066868298175Rat
10755459Coatc15Coat color QTL 150.01681coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)141983694464836944Rat
70214Niddm28Non-insulin dependent diabetes mellitus QTL 284.06blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)143999825175582726Rat
1300154Bp189Blood pressure QTL 1893.04arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)143088377768757901Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143032009280829842Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)144079346098037301Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin14826709053267090Rat
2313100Bss82Bone structure and strength QTL 8230.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143766971982669719Rat
7387267Uae42Urinary albumin excretion QTL 420.61urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)142216796767167967Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
2313397Coatc1Coat color QTL1coat/hair pigmentation trait (VT:0010463)coat/hair color measurement (CMO:0001808)141854133263541332Rat
2313048Bss84Bone structure and strength QTL 843.10.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143766971982669719Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144226252995023211Rat
2302045Pia39Pristane induced arthritis QTL 394.90.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G2a level (CMO:0002116)14826709053267090Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143905723783368335Rat
2313084Bss83Bone structure and strength QTL 832.90.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143766971982669719Rat

Markers in Region
D14Rat120  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21444,428,380 - 44,428,522 (+)MAPPERmRatBN7.2
Rnor_6.01446,083,897 - 46,084,038NCBIRnor6.0
Rnor_5.01445,885,797 - 45,885,938UniSTSRnor5.0
RGSC_v3.41447,091,611 - 47,091,753RGDRGSC3.4
RGSC_v3.41447,091,612 - 47,091,753UniSTSRGSC3.4
RGSC_v3.11447,094,002 - 47,094,144RGD
Celera1443,568,586 - 43,568,727UniSTS
SHRSP x BN Map1428.2599RGD
SHRSP x BN Map1428.2599UniSTS
Cytogenetic Map14p11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000002982   ⟹   ENSRNOP00000002982
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1444,387,393 - 44,478,041 (-)Ensembl
Rnor_6.0 Ensembl1446,050,750 - 46,054,022 (-)Ensembl
RefSeq Acc Id: NM_001017500   ⟹   NP_001017500
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81444,740,971 - 44,831,613 (-)NCBI
mRatBN7.21444,387,392 - 44,478,041 (-)NCBI
Rnor_6.01446,050,752 - 46,134,770 (-)NCBI
Rnor_5.01445,855,971 - 45,858,411 (-)NCBI
RGSC_v3.41447,040,366 - 47,158,361 (+)RGD
Celera1443,528,486 - 43,618,262 (-)RGD
Sequence:
RefSeq Acc Id: XM_039092290   ⟹   XP_038948218
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81444,740,965 - 44,831,763 (-)NCBI
mRatBN7.21444,387,386 - 44,478,233 (-)NCBI
RefSeq Acc Id: XM_039092291   ⟹   XP_038948219
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81444,765,047 - 44,832,173 (-)NCBI
mRatBN7.21444,389,805 - 44,478,344 (-)NCBI
RefSeq Acc Id: XM_063273466   ⟹   XP_063129536
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81444,775,646 - 44,832,180 (-)NCBI
RefSeq Acc Id: NP_001017500   ⟸   NM_001017500
- UniProtKB: Q6AYA8 (UniProtKB/Swiss-Prot),   A6JDI0 (UniProtKB/TrEMBL),   A6JDH8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000002982   ⟸   ENSRNOT00000002982
RefSeq Acc Id: XP_038948218   ⟸   XM_039092290
- Peptide Label: isoform X1
- UniProtKB: Q6AYA8 (UniProtKB/Swiss-Prot),   A6JDI0 (UniProtKB/TrEMBL),   A6JDH8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038948219   ⟸   XM_039092291
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063129536   ⟸   XM_063273466
- Peptide Label: isoform X2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AYA8-F1-model_v2 AlphaFold Q6AYA8 1-313 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561612 AgrOrtholog
BioCyc Gene G2FUF-15694 BioCyc
Ensembl Genes ENSRNOG00000002191 Ensembl, UniProtKB/Swiss-Prot
  ENSRNOG00055017870 UniProtKB/Swiss-Prot
  ENSRNOG00060015662 UniProtKB/Swiss-Prot
  ENSRNOG00065014106 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000002982.6 UniProtKB/Swiss-Prot
  ENSRNOT00055030239 UniProtKB/Swiss-Prot
  ENSRNOT00060026831 UniProtKB/Swiss-Prot
  ENSRNOT00065023286 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7126862 IMAGE-MGC_LOAD
InterPro DUF4699 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:498368 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:94129 IMAGE-MGC_LOAD
NCBI Gene 498368 ENTREZGENE
PANTHER CHROMOSOME 4 OPEN READING FRAME 19 UniProtKB/Swiss-Prot
  CHROMOSOME 4 OPEN READING FRAME 19 UniProtKB/TrEMBL
  CHROMOSOME 4 OPEN READING FRAME 19 UniProtKB/TrEMBL
  PTHR16106 UniProtKB/Swiss-Prot
Pfam DUF4699 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen C14h4orf19 PhenoGen
RatGTEx ENSRNOG00000002191 RatGTEx
  ENSRNOG00055017870 RatGTEx
  ENSRNOG00060015662 RatGTEx
  ENSRNOG00065014106 RatGTEx
UniProt A6JDH8 ENTREZGENE, UniProtKB/TrEMBL
  A6JDI0 ENTREZGENE, UniProtKB/TrEMBL
  CD019_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 C14h4orf19  similar to human chromosome 4 open reading frame 19  LOC498368  similar to RIKEN cDNA 0610040J01  Symbol and Name Changed 1299863 APPROVED
2021-03-09 LOC498368  similar to RIKEN cDNA 0610040J01  LOC100909799  ADP/ATP translocase 3-like  Data merged from RGD:6501590 737654 PROVISIONAL
2012-07-05 LOC100909799  ADP/ATP translocase 3-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-02-09 LOC498368  similar to RIKEN cDNA 0610040J01      Symbol and Name status set to provisional 70820 PROVISIONAL